7
Views
5
CrossRef citations to date
0
Altmetric
Original Article

New Directions in the Biology and Therapy of Chronic Myeloid Leukemia

, , , , , , , , , , , , , , , , , , , , , , , , , , & show all
Pages 89-95 | Received 30 Jun 1991, Published online: 01 Jul 2009

References

  • Strife A., Clarkson B. Introduction to the Biological and Clinical Understanding of CML. Chronic Myelogenous Leukemia: Molecular Approaches to Research and Therapy, A. Deisseroth, R. Arlinghaus. Marcel Dekker, Inc., New York 1990; 90, 1
  • Talpaz M., Kantarjian H., McCredie K. Hematological Remission and Cytogenetic Improvement Induced by Recombinant Human Interferon Alpha in CML. N. Eng. J. Med 1986; 314: 1065–1069
  • Thomas E. D., Clift R., Fefer A. Marrow Transplantation for the Treatment of CML. Ann. Int. Med 1986; 104: 155–163
  • Bacto-Babapulle F. Complete Remission After Autografting for CML. Leukemia Research 1987; 11: 1115–1117
  • Carroll M., Boswell H. S., Gabig T., Rapp U., Clark-Lewis I., May W. S. An Amplified IL-3 Induced c-raf Phosphorylation Accompanies the Mutant H-ras Induced Growth Acceleration by an IL-3 Dependent Myeloid Cell Line. Blood 1989; 74: 173a
  • Bischoff J. R., Friedman P. N., Marshak D. R., Prives C., Beach D. Human P53 is phosphorylated by p60-cdc2 and cyclin B-cdc2. Proc. Natl. Acad. Sci. USA 1990; 87: 4766–4770
  • DeCaprio J. A., Ludlow J. W., Lynch D., Furukawa Y., Griffen J., Warnes H. P., Huang C. M., Livingston D. M. The Product of the Retinoblastoma Susceptibility Gene has the Properties of a Cell Cycle Regulatory Element. Cell 1989; 58: 1085–95
  • Buchkovich K., Duffy C. A., Harlow E. The retinoblastoma protein is phosphorylated during specific phases of the cell cycle. Cell 1989; 58: 1097–1105
  • Kessler D. S., Levy D. E., Darnell J. E., Jr. Two interferon-induced nuclear factors bind a single promoter element in interferon-stimulated genes. Proc. Natl. Acad. Science USA 1988; 85: 8521–8525
  • Wedrychowski A., Seong D., Paslidis N., Johnson E., Howard O. M. Z., Sims S., Talpaz M., Kantarjian J. H., Hester J., Turpin J., Lopez-Berestein G., Gutterman J., Freireich E., Deisseroth A. Characterization of nuclear proteins which bind to interferon-inducible transcriptional enhancers in hematopoietic cells. J. Biol. Chem 1990; 265: 21433–21440
  • Upadhayaya G., Guba S. C., Sih S. A., Feinberg A. P., Tolporz M., Kavlayian H., Deisseroth A., Emerson S. Interferon alpha restores the deficient expression of the globohesion *** LFA 3 by CML progeniterales. ICI 1991, in press
  • Daley G., Baltimore D. Transformation of an Interleukin 3-Dependent Hematopoietic Cell Line by the CML-Specific P210bcr-abl protein. Proc. Natl. Acad. Sci. USA 1988; 85: 9312–9316
  • Hariharan I. K., Adams J. M., Cary S. Bcr-abl Oncogene Renders Myeloid Cell Line Factor Independent: Potential Autocrine Mechanism in CML. Oncogene Research 1988; 3: 387–399
  • Talpaz M. Interferon-alpha produces sustained cytogenetic responses in chronic myelogenous leukemia. Ann. Int. Med 1991; 114: 532–538, 1991.
  • Howard O. M. Z., Talpaz M., Kantarjian H., Seong D., Wedrychowski A., Paslidis N., Hester J., Cork A., Turpin J., Lopez-Berestein G., Trujillo J., Guterman J., Freireich E., Deisseroth A. Interferon Affects Nuclear Proteins in Cells of Clinically Sensitive CML Patients. Blood 1990; 75: 1117–1130
  • Seong D., Sims S., Johnson E., Howard O. M. Z., Reiter B., Hester J., Talpaz M., Kantarjian H., Deisseroth A. A Phosphatase Activity Present in Peripheral Blood Myeloid Cells of CML Patients but not Normal Individuals Alters Nuclear Protein Binding to Transcriptional Enhancers of Interferon-Inducible Genes. J. Clin. Invest 1990; 86: 1664–1670
  • Seong D., Sims S., Johnson E., Lyding J., Lopez A., Garovoy M., Talpaz M., Lopez-Berestein G., Reading C., Deisseroth A. Activation of Class I HLA Expression is Mediated by TNF-Alpha and Gamma-Interferon Through Protein Kinase C-Dependent Pathway in CML Cell Lines. Brit. J. Haematol 1991; 78: 359–367, 1991.
  • Wedrychowski A., Henzel W., Huston J., Paslidis N., Ellerson D., Seong D., Howard O. M. Z., Deisseroth A. Identification of Proteins Binding to Interferon-Inducible Transcriptional Enhancers in Hematopoietic Cells. 1991, preparation
  • Gao P. Q., Sims S., Deisseroth A. Functional Characterization of the Proteins Which Bind to the Interferon-Inducible Transcriptional Enhancers. 1991, Preparation
  • Johnson E., Deisseroth A. Analysis of Proteins Which Alters Interferon Sensitivity. 1991, preparation
  • Kantarjian H., Talpaz M., LeMaistre C. F., Spinolo J., Spitzer G., Yau J., Dicke K., Yagannath S., Dassuoth A. Structure Combination Chemotherapy and Autotegous Bone Marrow Transplantation Leads to the Reappearance of Philadelphia Chromosome Negative Cells in CML. Cancer 1991; 67: 2959–2965
  • Kantarjian H., Talpaz M., Gutterman J., Kantoyiannis D., Keating M., Estey E., O'Brien S., Rios M., Beran M., Deisseroth A. Treatment of CML in Accelerated and Blastic Phases with Daunorubicin, Cytosine Arabinoside, and GMCSF. 1991, Submitted
  • Deisseroth A. Integration of Molecular Biology and Genetics with Biological and Chemotherapeutic Approaches to the Management of Chronic Myelogenous Leukemia (CML). 4th International Management Symposium in ABMT, K. Dicke, J. Armitage, M. J. Evinger-Hodges, 1991; 229–237
  • Gordon M. Y., Dowding C. R., Riley G. P., Goldman J. M., Greaves M. F. Altered adhesive interactions with marrow stroma of haematopoietic progenitor cells in chronic myeloid leukaemia. Nature 1987; 288: 342–345
  • Yuan T. Y., Chen, Hanchun, Herst C. V., Guo J. Q., Reading C., Liu J., Arlinghaus R., Deisseroth A. In Vitro Antisense Oligonucleotides Homologous to BCR-ABL mRNA Inhibit Growth of Philadelphia Chromosome Positive Cell Lines. 1991, Preparation
  • Caracciolo D., Valtrero M., Venturelli D., Pesche C., Gewirtz A., Calabretta B. Lineage Specific Requirement of c-abl Function in Normal Myeloid Cells. Science 1989; 245: 1107–1110
  • Cornetta K., Moen R., Culver K., Morgan R., McLachlin J., Sturm S., Sclegue J., Lonshon W., Blaise M., Anderson W. F. Human Gene Therapy 1990; 1: 15–30

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.