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Original Article

Viral Infections in Leukemia and Bone Marrow Transplant Patients

Pages 115-125 | Published online: 01 Jul 2009

References

  • Saral R., Bums W. H., Laskin O. L., et al. Acy-clovir prophylaxis of herpes-simplex-virus infections. A randomized, double-blind, controlled trial in bone marrow transplant recipients. N. Engl. J. Med. 1981; 305: 63
  • Saral R., Ambinder R. F., Bums W. H., et al. Acyclovir prophylaxis against recrudescent herpes simplex virus infections in leukemia patients: a randomized, double-blind placebo controlled study. Ann. Intern. Med. 1983; 99: 773
  • Wingard J. R. Infectious and Noninfectious Systemic Consequences. Oral Complications of Cancer Therapies: Diagnosis, Prevention, and Treatment. NCI Monogr. 1990; 9: 21–26
  • Wade J. C., Newton B., Flournoy N., Meyers I. D. Oral acyclovir prophylaxis of herpes simplex virus infection after marrow transplant. Ann. Intern. Med. 1984; 100: 823
  • Shepp D. H., Newton B. A., Dandliker P. S., et al. Oral acyclovir therapy for mucocutaneous herpes simplex virus infection in immunocompromised marrow transplant recipients. Ann. Intern. Med. 1985; 102: 783
  • Meyers J. D., Wade J. C., Mitchell C. D., et al. Multicenter collaborative trial of intravenous acyclovir for the treatment of mucocutaneous herpes simplex virus infection in the immunocompromised host. Am. J. Med. 1982; 73A: 229
  • Mitchell C. D., Gentry S. R., Boen J. R., et al. Acyclovir therapy for mucocutaneous herpes simplex infections in immunocompromised patients. Lancet 1981; 2: 1389
  • Wade J. C., Newton B., McLaren C., et al. Treatment of mucocutaneous herpes simplex virus infection after marrow transplantation with intravenous acyclovir: a double-blind trial. Ann. Intern. Med. 1982; 96: 265
  • Selby P. J., Jameson B., Watson J. G., et al. Parenteral acyclovir therapy for herpes virus infections in man. Lancet 1980; 2: 1267
  • Wade J. C., McLaren C., Meyers J. D. Frequency and significance of acyclovir-resistant herpes simplex virus isolated from marrow transplant patients receiving multiple courses of treatment with acyclovir. J. Infect. Dis. 1983; 148: 1077–1082
  • Erlich K. S., Mills J., Chatis P., et al. Acyclovir-resistant herpes simplex virus infections in patients with the acquired immunodeficiency syndrome. N. Engl. J. Med. 1989; 320: 293–296
  • Wingard J. R., Piantadosi S., Bums W. H., et al. Cytomegalovirus Infections in Patients Treated by Intensive Cytoreductive Therapy with Marrow Transplant. Rev. Infect. Dis. 1990; 12(Suppl. 7)S805–S810
  • Winston D. J., Ho W. G., Champlin R. E. Cytomegalovirus infections after allogeneic bone marrow transplantation. Rev. Infect. Dis. 1990; 12(Suppl. 7)S776–S792
  • Meyers I. D., Floumoy N., Thomas E. D. Risk factors for cytomegalovirus infection after human marrow transplantation. J. Infect. Dis. 1986; 153: 478–488
  • Meyers J. D., Flournoy N., Thomas E. D. Non-bacterial pneumonia after allogeneic marrow transplantation: a review of ten years' experience. Rev. Infect. Dis. 1982; 4: 1119–1132
  • Paulin T., Ringden O., Lönnqvist B., Wahren B., Nilsson B. The importance of pre bone marrow transplantation serology in determining subsequent cytomegalovirus infection: analysis of risk factors. Scand. J. Infect. Dis. 1986; 18: 199–209
  • Henson D., Siegel S. E., Fucillo D. A., et al. Cytomegalovirus infections during acute childhood leukemia. J. Infect. Dis. 1972; 126: 469
  • Vaughan W. P., Saral R., Anderson L. R., Burke P. J. The frequency and pattern of cytomegalovirus (CMV) infection and shedding by patients who have received high dose times-sequential chemotherapy (TSC) for acute myelocytic leukemia (AML). Proc. 17th Annual Meeting Am. Soc. Clin. Oncol. 1981, 170, Abstract No. 673
  • Wade J. C., Bustamante C. I., Newman K. A., Devlin A. M. Cytomegalovirus: an important pathogen for adults receiving induction therapy for acute leukemia. 28th Annual Intersci. Conf. on Antimicrobial Agents and Chemotherapy. 1988, Abstract No. 1394
  • Wingard J. R., Chen D.H., Bums W. H., et al. Autologous Bone Marrow Transplantation: Comparison to Infection After Allogeneic Bone Marrow Transplantation. Blood 1988; 71: 1432–1437
  • Reusser P., Fisher L. D., Buckner C. D., Thomas E. D., Meyers J. D. Cytomegalovirus infection after autologous bone marrow transplantation: occurrence of cytomegalovirus disease and effect on engraftment. Blood 1990; 75: 1888–1894
  • Appelbaum F. R., Meyers J. D., Fefer A., et al. Nonbacterial nonfungal pneumonia following marrow transplantation in 100 identical twins. Transplantation 1982; 46: 61–65
  • Miller W., Flynn P., McCullough J., et al. Cytomegalovirus infection after bone marrow transplantation: an association with acute graft-versus-host disease. Blood 1986; 67: 1162–1167
  • Weiner R. S., Bortin M. M., Gale R. P., et al. Interstitial pneumonitis after bone marrow transplantation. Ann. Intern. Med. 1986; 104: 168–175
  • Wingard J. R., Mellits E. D., et al. Interstitial pneumonitis after allogeneic bone marrow transplantation: nine-year experience at a single institution. Medicine (Baltimore) 1988; 67: 175–186
  • Wade J. C., Hintz M., McGuffin R. W., et al. Treatment of cytomegalovirus pneumonia with high-dose acyclovir. Am. J. Med. 1982; 73A: 249
  • Shepp D. H., Dandliker P. S., de Miranda P., et al. Activity of 9– [2–hydroxy-l -(hydroxymethyl)ethoxymethyl] guanine in the treatment of cytomegalovirus pneumonia. Ann. Intern. Med. 1985; 103: 368
  • Meyers J. D., Flournoy N., Sanders J. E., et al. Prophylactic human leukocyte interferon after allogeneic marrow transplantation. Ann. Intern. Med. 1987; 107: 809
  • Reed E. C., Bowden R. A., Dandliker P. S., et al. Efficacy of cytomegalovirus immunoglobulin in marrow transplant recipients with cytomegalovirus pneumonia. J. Infect. Dis. 1987; 156: 641
  • Reed E. C., Bowden R. A., Dandliker P. S., et al. Treatment of cytomegalovirus pneumonia with ganciclovir and intravenous cytomegalovirus immunoglobulin in patients with bone marrow transplants. Ann. Intern: Med. 1988; 109: 783–788
  • Emanuel D., Cunningham I., Jules-Elysee K., et al. Cytomegalovirus pneumonia after bone marrow transplantation successfully treated with the combination of ganciclovir and high-dose intravenous immune globulin. Ann. Intern. Med. 1988; 109: 777–782
  • Schmidt G. M., Kovacs A., Zaia J. A., et al. Ganciclovir/Immunoglobulin combination therapy for the treatment of human cytomegalovirus-associated interstitial pneumonia in bone marrow allograft recipients. Transplantation 1988; 46: 905–907
  • Bratanow N. C., Ash R. C., Turner P. A. SUCcessful treatment of serious cytomegalovirus (CMV) disease with 9(1,3–dihydroxy-2–propoxymethyl)guanine (ganciclovir, DHPG) and intravenous immunoglobulin (IVIG) in bone marrow transplant (BMT) patients. Exp. Hematol. 1987; 15: 541, Abstract No. 254
  • Grundy J. E., Shanley J. D., Griffiths P. D. Is cytomegalovirus interstitial pneumonitis in transplant recipients an immunopathological condition. Lancet 1987; 2: 996
  • Aschan J., Ringden O., Ljungman P., Lönnqvist B., Ohlman S. Foscarnet for treatment of cytomegalovirus infections in bone marrow transplant recipients. Scand. J. Infect. Dis. 1992; 24: 143–150
  • Reed E. C., Wolford J. L., Kopecky K. J., et al. Ganciclovir for the treatment of cytomegalovirus gastroenteritis in bone marrow transplant patients. A randomized, placebo-controlled trial. Ann. Intern. Med. 1990; 112: 505–510
  • Winston D. J., Ho W. G., Lin C.H., et al. Intravenous immune globulin for prevention of cytomegalovirus infection and interstitial pneumonia after bone marrow transplantation. Ann. Intern. Med. 1987; 106: 12–18
  • Bowden R. A., Fisher L. D., Rogers K., Cays M., Meyers J. D. Cytomegalovirus (CMV)-specific intravenous immunoglobulin for the prevention of primary CMV infection and disease after marrow transplant. J. Infect. Dis. 1991; 164: 483–487
  • Bowden R. A., Sayers M., Flournoy N., et al. Cytomegalovirus immune globulin and seronegative blood products to prevent primary cytomegalovirus infection after marrow transplantation. N. Engl. J. Med. 1986; 314: 1006–1010
  • Winston D. J., Pollard R. B., Ho W. G., et al. Cytomegalovirus immune plasma in bone marrow transplant recipients. Ann. Intern. Med. 1982; 97: 11–18
  • Meyers J. D., Leszcynski J., Zaia J. A., et al. Prevention of cytomegalovirus infection by cytomegalovirus immune globulin after marrow transplantation. Ann. Intern. Med. 1983; 98: 442–446
  • O'Reilly R. J., Reich L., Gold J., et al. A randomized trial of intravenous hyperimmune globulin for the prevention of cytomegalovirus (CMV) infections following marrow transplantation: preliminary results. Transplant. Proc. 1983; 15: 1405–1411
  • Kubanek B., Ernest P., Ostendorf P., Schafer U., Woft H. Preliminary data of a controlled trial of intravenous hyperimmune globulin in the prevention of cytomegalovirus infection in bone marrow transplant recipients. Transplant. Prog. 1985; 17: 468–469
  • Winston D. J., Ho W. G., Lin C. H., et al. Intravenous immune globulin for prevention of cytomegalovirus infection and interstitial pneumonia after bone marrow transplantation. Ann. Intern. Med. 1987; 106: 12–18
  • Ringden O., Pihlstedt P., Volin L., et al. Failure to prevent cytomegalovirus infection by cytomegalovirus hyperimmune plasma: a randomized trial by the Nordic Bone Marrow Transplantation Group. Bone Marrow Transplant 1987; 2: 299–305
  • Sullivan K. M., Kopecky K. J., Jocum J., et al. Immunomodulatory and antimicrobial efficacy of intravenous immunoglobulin in bone marrow transplantation. N. Engl. J. Med. 1990; 323: 105–712
  • Bass E. B., Powe N. R., Graziano S. L., et al. Efficacy of Intravenous Immune Globulin in Preventing Complications of Bone Marrow Transplantation: A Meta Analysis. Bone Marrow Transplant 1992, In Press
  • Winston D. J., Ho W. G., Gale R. P., Champlin R. E. Treatment and prevention of interstitial pneumonia after bone marrow transplantation. Progress in bone marrow transplantation, R. P. Gale, R. E. Champlin. Alan R. Liss, New York 1987; 525–544
  • Miller W., McCullough J., Balfour H. H., et al. Prevention of CMV infection by blood products: a randomized trial (abstract # K128). J. Cell. Biochem. 1988; 12(Suppl. C)93
  • Bowden R. A., Sayers M., Slichter S. J., et al. Use of leukocyte-poor transfusions to prevent CMV infection after marrow transplant. Proceedings of the 2nd International CMV Workshop, San Diego, CA, 1989
  • Meyers J. D., Reed E. C., Shepp D. H., et al. Acyclovir for prevention of cytomegalovirus infection and disease after allogeneic marrow transplantation. N. Engl. J. Med. 1988; 318: 70
  • Schmidt G. M., Horak D. A., Niland J. C., et al. A randomized, controlled trial of prophylactic ganciclovir for cytomegalovirus pulmonary infection in recipients of allogeneic bone marrow transplant patients. N. Engl. J. Med. 1991; 324: 1005–1011
  • Goodrich J. M., Mori M., Cleaves C. A., et al. Early treatment with ganciclovir to prevent cytomegalovirus disease after allogeneic bone marrow transplant. N. Engl. J. Med. 1991; 325: 1601–1607
  • Goodrich J. M., Bowden R. A., Fisher L., et al. Ganciclovir prophylaxis to prevent cytomegalovirus disease after allogeneic marrow transplant. Ann. Intern. Med. 1993; 118: 173–178
  • Winston D. J., Ho W. G., Bartoni K., et al. Ganciclovir prophylaxis of cytomegalovirus infection and disease in allogeneic bone marrow transplant recipients. Ann. Intern. Med. 1993; 118: 179–184
  • Atkinson K., Downs K., Golenia M., et al. Prophylactic use of ganciclovir in allogeneic bone marrow transplantation: absence of clinical cytomegalovirus infection. Br. J. Haematol. 1991; 79: 57–52
  • Meyers J. D., Ljungman P., Fisher L. D. Cytomegalovirus excretion as a predictor of cytomegalovirus disease after marrow transplantation: importance of cytomegalovirus viremia. J. Infect. Dis. 1990; 162: 373–380
  • Cleaves C. A., Smith T. F., Shuster E. A., Pearson G. R. Comparison of standard tube and shell vial cell culture techniques for the detection of cytomegalovirus in clinical specimens. J. Clin. Microbiol. 1985; 21: 217
  • Crawford S. W., Bowden R. A., Hackman R. C., et al. Rapid detection of cytomegalovirus pulmonary infection by bronchoalveolar lavage and centrifugation culture. Ann. Intern. Med. 1988; 108: 180–185
  • Spector S. A., Memll R., Wolf D., et al. Detection of human cytomegalovirus in plasma of AIDS patients during acute visceral disease by DNA amplification. J. Clin. Microbiol. 1992; 30: 2359–2365
  • Brytting M., Xu W., Wahren B., et al. Cytomegalovirus DNA detection in sera from patients with active cytomegalovirus infections. J. Clin. Microbiol. 1992; 30: 1937–1941
  • Wolf D., Spector S. A. Early diagnosis of human cytomegalovirus disease in transplant recipients by DNA amplification in plasma. Abstracts of the Thirty-second Interscience Conference on Antimicrobial Agents and Chemotherapy, Atlanta, 1992, 317, Abstract #1241
  • Vlieger A. M., Boland G. J., Jiwa N. M., et al. Cytomegalovirus antigenemia assay or PCR can be used to monitor ganciclovir treatment in bone marrow transplant recipients. Bone Marrow Transplant 1992; 9: 247–253
  • van der Bij W., Torensma R., van Son W. J., et al. Rapid immunodiagnosis of active cytomegalovirus infection by monoclonal antibody staining of blood leucocytes. J. Med. Virol. 1988; 25: 179–188
  • Jiwa N. M., van de Rijke F. M., Mulder A., et al. An improved immunocytochemical method for detection of human cytomegalovirus antigens in peripheral blood leucocytes. Histochemistry 1989; 91: 345–349
  • Boeckh M., Boweden R. A., Goodrich J. M., et al. Cytomegalovirus antigen detection in peripheral blood leukocytes after allogeneic marrow transplantation. Blood 1992; 80: 1358–1364
  • Buller R. S., Bailey T. C., Ettinger N. A. Use of a modified shell vial technique to quantitate cytomegalovirus viremia in a population of solid-organ transplant recipients. J. Clin. Microbiol. 1992; 30: 2620–2624
  • Locksley P. R. M., Flournoy N., Sullivan K. M., Meyers J. D. Infection with varicella-zoster virus after marrow transplantation. J. Infect. Dis. 1985; 152: 1172–1181
  • Schiller G. J., Nimer S. D., Gajewski J. L., Golde D. W. Abdominal presentation of varicella-zoster infection in recipients of allogenic bone marrow transplantation. Bone Marrow Transplant 1991; 7: 489–491
  • Atkinson K., Meyers J. D., Storb R., Prentice R. L., Thomas E. D. Varicella-zoster virus infection after marrow transplantation for aplastic anemia or leukemia. Transplantation 1980; 29: 47
  • Atkinson K., Farewell V., Storb R., et al. Analysis of late infections after human bone marrow transplantation: role of genotypic nonidentity between marrow donor and recipient and of nonspecific suppressor cells in patients with chronic graft-versus-host disease. Blood 1982; 60: 714
  • Schuchter L. M., Wingard J. R., Piantadosi S., Bums W. H., Santos G. W., Saral R. Herpes Zoster Infection After Autologous Bone Marrow Transplantation. Blood 1989; 74: 1424–1427
  • Balfour H. H., Jr., Bean B., Laskin O. L., , the Burroughs Wellcome Collaborative Acyclovir Study Group, et al. Acyclovir halts progression of herpes zoster in immunocompromised patients. N. Engl. J. Med. 1983; 308: 1448–1453
  • Meyers J. D., Wade J. C., Shepp D. H., Newton B. Acyclovir treatment of varicella-zoster virus infection in the compromised host. Transplantation 1984; 37: 571
  • Serota F. T., Starr S. E., Bryan C. K., et al. Acyclovir treatment of herpes zoster infections, use in children undergoing bone marrow transplantation. J. Am. Med. Assoc. 1982; 247: 2132–2135
  • Ljungman P., Lönnqvist B., Ringdén O., Skinhöj P., Gahrton G., for the Nordic bone Marrow Transplant Group. A randomized trial of oral versus intravenous acyclovir for treatment of herpes zoster in bone marrow transplant recipients. Bone Marrow Transplant 1989; 4: 613–615
  • Shepp D. H., Dandliker P. S., Meyers J. D. Treatment of varicella-zoster virus infection in severely immunocompromised patients: a randomized comparison of acyclovir and vidarabine. N. Engl. J. Med. 1986; 314: 208–212
  • Zaia J. A., Levin M. J., Preblud S. R., et al. Evaluation of varicella-zoster immune globulin: protection of immunosuppressed children after household exposure to varicella. J. Infect. Dis. 1983; 147: 737
  • Gershon A. A. Live attenuated varicella vaccine: perspective. J. Infect. Dis. 1985; 152: 859
  • Gershon A. A. Live attenuated varicella vaccine. J. Pediatr. 1987; 110: 154
  • Gershon A. A., Steinberg S. P., The Varicella Vaccine Collaborative Study Group of the NIAID. Persistence of immunity of varicella in children with leukemia immunized with live attenuated varicella vaccine. N. Engl. J. Med. 1989; 320: 892
  • Gershon A. A., Steinberg S. P., the National Institute of Allergy and Infectious Diseases Varicella Vaccine Collaborative Study Group. Live attenuated varicella vaccine: protection in healthy adults compared with leukemic children. J. Infect. Dis. 1990; 161: 661
  • Lawrence R., Gershon A. A., Holzman R., et al. The risk of zoster after varicella vaccination in children with leukemia. N. Engl. J. Med. 1988; 318: 543
  • Diaz P. S., Au D., Smith S., et al. Lack of transmission of the live attenuated varicella vaccine virus to immunocompromised children after immunization of their siblings. Pediatrics 1991; 87: 166–170
  • Ljungman P., Lönnqvist B., Gahrton G., et al. Clinical and subclinical reactivations with varicella-zoster virus in immunocompromised patients. J. Infect. Dis. 1986; 153: 840–844
  • Ljungman P., Wilczek H., Gahrton G., et al. Long-term acyclovir prophylaxis in bone marrow transplant recipients and lymphocyte proliferation responses to herpes virus antigens in-vitro. Bone Marrow Transplant 1986; 1: 185–192
  • Perren T. J., Powles R. L., Easton D., et al. Prevention of herpes zoster in patients by long-term oral acyclovir after allogeneic bone marrow transplantation. Am. J. Med. 1988; 85: 99–101
  • Sempere A., Sanz G. F., Senent L., et al. Long-term acyclovir prophylaxis for prevention of varicella zoster virus infection after autologous blood stem cell transplantation in patients with acute leukemia. Bone Marrow Transplant 1992; 10: 495–498
  • Shanley J. D., Pesanti E. L., Nugent K. M. The pathogenesis of pneumonitis due to murine cytomegalovirus. J. Infect. Dis. 1982; 146: 388–96
  • Shanley J. D., Pomeroy C., Via C. S., Shearer G. M. Interstitial pneumonitis during murine cytomegalovirus infection and graft-versus-host reaction: effect of ganciclovir therapy. J. Infect. Dis. 1988; 158: 1391–1394
  • Shanley J. D., Pesanti E. L. The relation of viral replication to interstitial pneumonitis in murine cytomegalovirus lung infection. J. Infect. Dis. 1985; 151: 454–458
  • Shanley J. D. Murine cytomegalovirus pneumonitis in T cell deficient nude mice. Abstracts of the 12th Herpesvirus Workshop. 1987
  • Grundy J. E., Shanley J. D., Shearer G. M. Augmentation of graft versus host reaction by cytomegalovirus infection resulting in interstitial pneumonitis. Transplantation 1985; 39: 548–553
  • Quinnan G. V., Jr., Kirmani N., Rook A. H., et al. HLA-restricted T lymphocyte and non-T lymphocyte cytotoxic responses correlate with recovery from cytomegalovirus infection in bone marrow transplant recipients. N. Engl. J. Med. 1982; 307: 7–13
  • Quinnan G. V., Jr., Bums W. H., Kirmani N., et al. HLA-restricted cytotoxic T lymphocytes are an early immune response and important defense mechanism in cytomegalovirus infections. Rev. Infect. Dis. 1984; 6: 156–163
  • Greenberg P. D., Reusser P., Goodrich J. M., et al. Development of a treatment regimen for human cytomegalovirus (CMV) infection in bone marrow transplant recipients by adoptive transfer of donor-derived CMV-specific T cell clones expanded in vitro. Ann. NY Acad. Sci. 1991; 636: 184–195
  • Tricot G., De Clercq M. A., Boogaerts M. A., Verwilghen R. L. Oral Bromovinyldeoxyuridine therapy for herpes simplex and varicella-zoster virus infections in severely immunosuppressed patients: a preliminary clinical trial. J. Med. Virol. 1986; 18: 11–20
  • Machida H., Nishitani M. Drug susceptibilities of isolates of varicella-zoster virus in a clinical study of oral brovavir. Microbiol. Immunol. 1990; 34: 407–411
  • Leyland-Jones B., Donnelly H., Groshen S., et al. 2–Fluro-5–Iodo-arabinosylcytosine, a new potent antiviral agent: efficacy in immunosuppressed individuals with herpes zoster. J. Infect. Dis. 1986; 154: 430–436

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