114
Views
126
CrossRef citations to date
0
Altmetric
Original Article

Fludarabine and Arabinosylcytosine Therapy of Refractory and Relapsed Acute Myelogenous Leukemia

, , , , &
Pages 343-350 | Received 08 Aug 1992, Published online: 01 Jul 2009

References

  • Freireich E. Arabinosyl cytosine: A 20-year Update. J. Clin. Oncol 1987; 5: 523–524
  • Chu M., Fischer G. Comparative studies of Leukemia cells sensitive and resistant to cytosine arabinoside. Biochem. Pharmacol 1965; 14: 333–341
  • Estey E., Plunkett W., Dixon D., Keating M., McCredie K., Freireich E. Variables predicting response to high dose cytosine arabinoside therapy in patients with refractory acute leukemia. Leukemia 1987; 1: 580–583
  • Gandhi V., Plunkett W. Modulation of arabinosyl nucleoside metabolism by arabinosylnucleotides in human Leukemia cells. Cancer Res 1988; 48: 329–334
  • Gandhi V., Estey E., Kemena A., Keating M., Plunkett W. Potentiation of arabinoslylcytosine triphosphate metabolism in Leukemia blasts by fludarabine monophosphate during therapy. Proc. Am. Soc. Clin. Oncol 1991; 10: 95
  • Gandhi V., Estey E., Keating M., Plunkett W. Biochemical modulation of arabinosycytosine for therapy of leukemias. Leukemia and Lymphoma 1992, (in press)
  • Warrell R., Berman E. Phase I and II study of fludarabine phosphate in leukemia: Therapeutic efficacy with delayed central nervous system toxicity. J. Clin. Oncol 1986; 4: 74–79
  • Spriggs D., Stopa E., Mayer R., Schoene W., Kufe D. Fludarabine phosphate (NSC 312878) infusions for the treatment of acute leukemia: Phase I and neuropathological study. Cancer Res 1986; 46: 5953–5958
  • Chun H., Leyland-Jones B., Caryk S., Hoth D. Central nervous system toxicity of fludarabine phosphate. Cancer Treat. Rept 1986; 70: 1225–1228
  • Keating M., Kantarjian H., O'Brien S., Roller C., Talpaz M., Schachner J., Childs C., Freireich E., McCredie K. Fludarabine: a new agent with marked cytoreductive activity in untreated chronic lymphocytic leukemia. J. Clin. Oncol 1991; 9: 44–49
  • Keating M., Kantarjian H., Smith T., Estey E., Walters R., Andersson B., Beian M., McCredie K., Freireich E. Response to salvage therapy and survival after relapse in acute myelogenous leukemia. J. Clin. Oncol 1989; 7: 1071–1080
  • Hiddemann W., Martin W.-R., Sauerland C.-M., Heineike A., Biichner T. Definition of refractoriness against conventional chemotherapy in acute myeloid leukemia: A proposal based on the results of retreatment by thioguanine, cytosine arabinoside, and daunorubicin (TAD 9) in 150 patients with relapse and standardized first line therapy. Leukemia 1990; 4: 184–188
  • Kantarjian H., Estey E., Plunkett W., Keating M., Walters R., Iacoboni M., McCredie K., Freireich E. Phase I–II clinical and pharmacologic studies of high-dose cytosine arabinoside in refractory leukemia. Am. J. Med 1986; 81: 387–394
  • Plunkett W., Liliemark J., Adams T., Nowak B., Estey E., Kantarjian H., Keating M. Saturation of l-b˜-D-arabinosylcytosine 5′-triphosphate accumulation in Leukemia cells during high dose l-b˜-D-arabinofuranosylcyto-sine therapy. Cancer Res 1987; 47: 3005–3011
  • Danhauser L., Plunkett W., Keating M. J., Cabanillas F. 9-b˜-D-Arabinofuranosyl-2-fluoroadenine 5′-monophos-phate pharmacokinetics in plasma and tumor cells of patients with relapsed Leukemia and lymphoma. Cancer Chemother. Pharmacol 1986; 18: 145–152
  • Estey E., Plunkett W., Keating M., McCredie K., Freireich E. Cytosine arabinoside in intermediate doses' as therapy for patients with acute myelogenous leukemia. Proc. Am. Assoc. Cancer Res 1988; 29: 209
  • Estey E., Plunkett W., Kantarjian H., Rios M., Keating M. 1992, Cytosine arabinoside in intermediate doses for patients with acute myeloid leukemia. Leukemia Lymphoma in press
  • Herzig R., Wolff S., Lazarus H., Phillips R., Karanes C., Herzig G. High-dose cytosine arabinoside therapy for refractory leukemia. Blood 1983; 62: 361–369
  • Preisler H., Epstein J., Barcos M., Priore R., Raza A., Growman R., Vogler R., Winton E., Grunwald H., Rai K., Brennan J., Bennett J., Goldberg A., Gottlieb A., Chervnick P., Joyce R., Miller K., Larson R., D'Arrigo P., Doeblin T., Stein M., Bloom M., Steel L., Lee H. Prediction of response of acute nonlymphocytic Leukemia to therapy with 'high-dose' cytosine arabinoside. Br. J. Haematol 1984; 58: 19–32
  • Vogler R., Preisler H., Winton H., Gottlieb A., Goldberg J., Brennan J., Grunwald H., Rai K., Growman G., Miller K., Chervenick P., Azarnia N. Randomized trial of high-dose cytarabine versus amsacrine in acute myelogenous Leukemia in relapse: A Leukemia intergroup study. Cancer Treat. Rpt 1986; 70: 455–459
  • Willemze R., Fibbe W., Zwaan F. Experience with intermediate and high dose cytosine arabinoside in refractory acute leukemia. Oncologia 1983; 6: 200–204
  • van Prooijen H., Dekker A., Punt K. The use of intermediate dose cytosine arabinoside (ID-AraC) in the treatment of acute non-lymphoblastic leukemia in relapse. Br. J. Haematol 1984; 57: 291–299
  • Estey E., Kantarjian H., Freireich E., McCredie K., Deisseroth A., Keating M. Long-term results with continuous-infusion high-dose ara-C as primary treatment of newly-diagnosed AML. Proc. Am. Soc. Clin. Oncol 1990; 9: 212
  • Samuels B., Larson R., Le Beau M., Daly K., Bitter M., Bardiman J., Barker C., Rowley J., Golumb H. Specific chromosomal abnormalities in acute nonlymphocytic leukemia correlate with drug susceptibility in vivo. Leukemia 1988; 2: 79–83
  • Keating M., Smith T., Kantarjian H., Cork A., Walters R., Trujillo J., McCredie K., Gehan E., Freireich E. Cytogenetic pattern in acute myelogenous leukemia. A major reproducible determinant of outcome. Leukemia 1988; 2: 403–412
  • Schiffer C., Lee E., Tomiyasu T., Wiernik P., Testa J. Prognostic impact of cytogenetic abnormalities in patients with de novo acute nonlymphocytic leukemia. Blood 1989; 73: 263–270
  • Koistinen P., Wang C., Yang G., Williams D., Lyman S., Minden M., McCulloch E. OCI/AML-4 an acute myeloblastic leukemia cell line: Regulation and response to cytosine arabinoside. Leukemia 1991; 5: 704–711

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.