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Original Article

Molecular Cytogenetic Analysis of RB-1 Deletions in Chronic B-Cell Leukemias

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Pages 97-103 | Received 17 Feb 1994, Published online: 01 Jul 2009

References

  • Pittman S., Catovsky D. Prognostic significance of chromosome abnormalities in chronic lymphocytic leukemia. Br. J. Haematol. 1984; 58: 649–660
  • Han T., Sadamori N., Block A. M. W., Xiao H., Henderson E. S., Emrich L., Sandberg A. A. Cytogenetic studies in chronic lymphocytic leukemia, prolymphocytic leukemia and hairy cell leukemia: A progress report. Nouv. Rev. Fr. Hematol. 1988; 30: 393–395
  • Oscier D. G., Fitchett M., Hamblin T. J. Chromosomal abnormalities in B-CLL. Nouv. Rev. Fr. Hematol. 1988; 30: 397–398
  • Juliusson G., Oscier D. G., Fitchett M., Ross F. M., Stockdill G., Mackie M. J., Parker A. C., Castoldi G. L., Cuneo A., Knuutila S., Elonen E., Gahrton G. Prognostic subgroups in B-cell chronic lymphocytic leukemia defined by specific chromosomal abnormalities. N. Engl. J. Med. 1990; 323: 720–724
  • Juliusson G., Oscier D., Gahrton G., For the International Working Party on Chromosomes in CLL (IWCCLL). Cytogenetic findings and survival in B-cell chronic lymphocytic leukemia. Second IWCCLL compilation of data on 662 patients. Leukemia and Lymphoma 1991; 5: 21–25
  • Knuutila S., Elonen E., Teerenhovi L., Rossi L., Leski-nen R., Bloomfield C. D., de la Chapelle A. Trisomy 12 in B cells of patients with B-cell chronic lymphocytic leukemia. N. Engl. J. Med. 1986; 314: 865–869
  • Perez Losada A., Wessman M., Tiainen M., Hopman A. H. N., Willard H. F., Sole F., Caballin M. R., Woessner S., Knuutila S. Trisomy 12 in chronic lymphocytic leukemia: An interphase cytogenetic study. Blood 1991; 78: 775–779
  • Lichter P., Boyle A. L., Cremer T., Ward D. C. Analysis of genes and chromosomes by nonisotopic in situ hybridization. GATA 1991; 8: 24–35
  • Tkachuk D. C., Pinkel D., Kuo W. L., Weier H. U., Gray J. W. Clinical applications of fluorescence in situ hybridization. GATA 1991; 8: 67–74
  • Cremer T., Landegent J., Bruckner A., Scholl H. P., Schardin M., Hager H. D., Devilee P., Pearson P., van der Ploeg M. Detection of chromosome aberrations in the human interphase nucleus by visualization of specific target DNAs with radioactive and non-radioactive in situ hybridization techniques: diagnosis of trisomy 18 with probe LI.84. Hum. Genet. 1986; 74: 346–352
  • Dohner H., Pohl S., Bulgay-Morschel M., Stilgenbauer S., Bentz M., Lichter P. Trisomy 12 in chronic lymphoid leukemias-a metaphase and interphase cytogenetic analysis. Leukemia 1993; 7: 516–520
  • Anastasi J., Le Beau M. M., Vardiman J. W., Fernald A. A., Larson R. A., Rowley J. D. Detection of trisomy 12 in chronic lymphocytic leukemia by fluorescence in situ hybridization to interphase cells: A simple and sensitive method. Blood 1992; 79: 1796–1801
  • Cuneo A., Wlodarska I., Sayed Aly M L, Piva N., Carli M. G., Faglioli F., Tallarico A., Pazzi I., Ferrari L., Cas-siman J. J., van den Berghe H., Castoldi G. L. Non-radioactive in situ hybridization for the detection and monitoring of trisomy 12 in B-cell chronic lymphocytic leukaemia. Br. J. Hematol. 1992; 81: 192–196
  • Raghoebier S., Kibbelaar R. E., Kleiverda K., Kluin-Nele-mans J. C., van Krieken J. H. J.M., Kok F., Kluin Ph. M. Mosaicism of trisomy 12 in chronic lymphocytic leukemia detected by non-radioactive in in situ hybridisation. Leukemia 1992; 6: 1220–1226
  • Escudier S. M., Pereira-Leaby J. M., Drach J. W., Weier H. U., Goodacre A. M., Cork M. A., Trujillo J. M., Keating M. J., Andreeff M. Fluorescence in situ hybridization and cytogenetic studies of trisomy 12 in chronic lymphocytic leukemia. Blood 1993; 81: 2702–2707
  • Que T. H., Garcia Marco J., Ellis J., Matutes E., Brito Babapulle V., Boyle S., Catovsky D. Trisomy 12 in chronic lymphocytic leukemia detected by fluorescence in situ hybridization: Analysis by stage, immunophenotype, and morphology. Blood 1993; 82: 571–575
  • Fitchett M., Griffiths M. J., Oscier D. G., Johnson S., Seabright M. Chromosome abnormalities involving band 13q14 in hematologic malignancies. Cancer Genet. Cy-togenet. 1987; 24: 143–150
  • Zech L., Mellstedt H. Chromosome 13-A new marker for B-cell chronic lymphocytic leukemia. Hereditas 1988; 108: 77–84
  • Peterson L. C., Lindquist L. L., Church S., Kay N. E. Frequent clonal abnormalities of chromosome band 13q14 in B-cell chronic lymphocytic leukemia: Multiple clones, subclones, and nonclonal alterations in 82 Midwestern patients. Genes Chrom. Cancer. 1992; 4: 273–280
  • Stilgenbauer S., Dohner H., Bulgay-Morschel M., Weitz S., Bentz M., Lichter P. High frequency of monoallelic retinoblastoma gene deletion in B-cell chronic lymphoid leukemia shown by interphase cytogenetics. Blood 1993; 81: 2118–2124
  • Bennett J. M., Catovsky D., Daniel M. T., Flandrin G., Galton D. A. G., Gralnick H. R., Sultan C, The French-American-British (FAB) Cooperative Group Proposals for the classification of chronic (mature) B and T lymphoid leukaemias. J. Clin. Pathol. 1989; 42: 567–584
  • Wiggs J., Nordenskjold M., Yandell D., Rapaport J., Grondin V., Janson M., Werelius B., Petersen R., Craft A., Riedel K., Liberfarb R., Walton D., Wilson W., Dryja T. P. Prediction of the risk of hereditary retinoblastoma, using DNA polymosphisms within the retinoblastoma gene. N. Engl. J. Med. 1988; 318: 151–157
  • Kay N. E., Suen R., Ranheim E., Peterson L. C. Confirmation of Rb gene defects in B-CLL clones and evidence for variable predominance of the Rb defective cells within the CLL clone. Br. J. Haematol. 1992; 84: 257–264
  • Ahuja H. G., Jat P. S., Foti A., Bar-Eli M., Cline M. J. Abnormalities of the retinoblastoma gene in the pathogenesis of acute leukemia. Blood 1991; 78: 3259–3268
  • Ginsberg A. M., Raffeld M., Cossman J. In-activation of the retinoblastoma gene in human lymphoid neoplasms. Blood 1991; 77: 833–840
  • Raghoebier S., van Krieken J. H. J.M., Kluin-Nelemans J. C., Gillis A., van Ommen G. J. B., Ginsberg A. M., Raffeld M., Kluin P. M. Oncogene rearrangements in chronic B-cell leukemia. Blood 1991; 77: 1560–1564
  • Liu Y., Grander D., Soderhall S., Juliusson G., Gahrton G., Einhorn S. Retinoblastoma gene deletions in B-cell chronic lymphocytic leukemia. Genes Chrom. Cancer 1992; 4: 250–256
  • Abramson D. H., Ellsworth R. M., Kitchin D., Tung G. Second nonocular tumors in retinoblastoma survivors. Ophthalmology 1984; 91: 1351–1355
  • Brown A. G., Ross F. M., Dunne E. M., Steel C. M., Weit-Thompson E. M. Evidence for a new tumour suppressor locus (DBM in human B-cell neoplasia telomeric to the retinoblastoma gene. Nature Genet. 1993; 3: 67–72
  • Hawthorn L. A., Chapman R., Oscier D., Cowell J. K. The consistent 13q14 translocation breakpoint seen in chronic B-cell leukaemia involves deletion of the D13S25 locus which lies distal to the retinoblastoma predisposition gene. Oncogene 1993; 8: 1415–1419
  • Liu Y., Szekely L., Grander D., Soderhall S., Juliusson G., Gahrton G., Linder S., Einhorn S. Chronic lymphocytic leukemia cells with allelic deletions at 13q14 commonly have one intact RBI gene: Evidence for a role of an adjacent locus. Proc. Natl. Acad. Sci. USA 1993; 90: 8697–8701
  • Joos S., Falk M. H., Lichter P., Haluska F. G., Henglein B., Lenoir G. M., Bornkamm G. W. Variable breakpoints in Burkitt lymphoma cells with chromosomal t(8;14) translocation separate c-myc and the IgH locus up to several hundred kb. Hum. Molec. Genet. 1992; 1: 625–632
  • Henglein B., Synovzik H., Groitl P., Bornkamm G. W., Hartl P., Lipp M. Three breakpoints of variant t(2;8) translocations in Burkitt's lymphoma cells fall within a region 140 kilobases distal from c-myc. Mol. Cell. Biol. 1989; 9: 2105–2113

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