Main Drug-Metabolizing Enzyme Systems in Human Non-Hodgkin's Lymphomas Sensitive or Resistant to Chemotherapy

References

• De Vita V.T., Hellman S., Rosenberg S.A. Cancer, principles and practice of oncology, Second edition. Lippincott JB Co., Philadelphia 1985
   Google Scholar
• Fisher R.I., Gaynor E.R., Dahlberg S., Oken M.M., Grogan T.M., Mize E.M., Glick J.H., Coltman C.A., Miller T.P. Comparison of a standard regimen (CHOP) with three intensive chemotherapy regimens for advanced non-Hodgkin's lymphoma. N. Engl, J. Med. 1993; 328: 1002–1006
   PubMed Web of Science ®Google Scholar
• De Vita V.T., Hubbard S.M., Longo D.L. The chemotherapy of lymphomas: looking back, moving forward—The Richard and Hinda Rosenthal Foundation Award Lecture. Cancer Res. 1987; 47: 5810–5824
   PubMed Web of Science ®Google Scholar
• Weick J.K., Dahlberg S., Fisher R.I., Dana B., Miller T.P., Balcerzak S.P., Pierce H.I. Combination chemotherapy of intermediaire-grade and high-grade non-Hodgkin's lymphoma with MACOP-B: A Southwest Oncology Group study. J. Clin. Oncol. 1991; 9: 748–753
   PubMed Web of Science ®Google Scholar
• Yi P.I., Coleman M., Saltz L., Norton L., Topilow A.A., Adler K., Bernhardt B. Chemotherapy for large cell lymphoma: A status update. Semin. Oncol. 1990; 17: 60–73
   PubMed Web of Science ®Google Scholar
• Guengerich F.P. Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy. Cancer Res. 1988; 48: 2946–2954
   PubMed Web of Science ®Google Scholar
• El Mouelhi M., Didolkar M.S., Elias E.G., Guengerich F.P., Kauffman F.C. Hepatic drug-metabolizing enzymes in primary and secondary tumors of human liver. Cancer Res. 1987; 47: 460–466
   PubMed Web of Science ®Google Scholar
• Clarke L., Waxmann D.J. Oxydative metabolism of cyclophosphamide: identification of the hepatic monooxygenase catalyst of drug activation. Cancer Rex 1989; 49: 2344–2350
   PubMed Web of Science ®Google Scholar
• Cowan K.H., Batist G., Tulpule A., Sinha B.K., Myers C.E. Similar biochemical changes associated with multidrug resistance in human breast cancer cells and carcinogen-induced resistance to xenobiotics in rats. Proc. Natl. Acad. Sci. 1986; 83: 9328–9332
   PubMed Web of Science ®Google Scholar
• Wolf R.C., Macpherson J.S., Smyth J.F. Evidence for the metabolism of Mitozantrone by microsomal glutathione transferases and 3-methylcholantrene glucuronosyl transferases. Biochem. Pharmacol. 1986; 35: 1577–1581
   PubMed Web of Science ®Google Scholar
• Robson C.N., Lewis A.D., Wolf C.R., Hayes J.D., Hall A., Proctor S.J., Harris A.L., Hickson I.D. Reduced levels of drug-induced DNA cross-linking in nitrogen-mustard resistant Chinese hamster ovary cells expressing elevated glutathione S-transferase activity. Cancer Rex 1987; 41: 6022–6027
   Google Scholar
• Gupta V., Singh S.V., Ahmad H., Medh R.D., Awasthi Y.C. Glutathione and glutathione S-transferases in human plasma cell line resistant to melphalan. Biochem. Phurmacol. 1989; 38: 1993–2000
   PubMed Web of Science ®Google Scholar
• Batist G., Tulpule A., Sinha B.K., Katki A.G., Myers C.E., Cowan K.H. Overexpression of a novel glutathione transferase in multidrug-resistant human breast cancer cells. J. Biol. Chem. 1986; 261: 15544–15549
   PubMed Web of Science ®Google Scholar
• McGrown A.T., Fox B.W. A proposed mecanism of resistance to cyclophosphamide and phosphoramide mustard in a Yoshiba cell line. in vitro. Cancer Chemother. Pharmacol. 1986; 17: 223–226
   PubMed Web of Science ®Google Scholar
• Lewis A.D., Hickson I.D., Robson C.N., Harris A.L., Hayes J.D., Griffiths S.A., Manson M.M., Hall A.E., Moss J.E., Wolf C.R. Amplification and increase of alpha class glutathione S-transferase-encoding genes associated with resistance to nitrogen mustards. Proc. Natl. Acad. Sci. 1988; 85: 8511–8515
   PubMed Web of Science ®Google Scholar
• Bolton M.G., Colvin O.M., Hilton J. Specificity of isoenzymes of murine hepatic glutathione S-transferase for the conjugation of glutathione with I-phenylalanine mustard. Cancer Res. 1991; 51: 2410–2415
   PubMed Web of Science ®Google Scholar
• Puchalski R.B., Fahl W.E. Expression of recombinant glutathione S-transferase p, Ya, or Yb1 confers resistance to alkylating agents. Proc. Natl. Acad. Sci. 1990; 87: 2443–2447
   PubMed Web of Science ®Google Scholar
• Lewis A.D., Duran G.E., Sikic B.I. Transfection of a full length human alpha class glutathione S-transferase cDNA confers resistance to chemotherapic agents. Proc. Am. Assoc. Cancer Res. 1992; 33: 497
   Google Scholar
• Beaune P.H., Flinois J.P., Kiffel L., Kremers P., Leroux J.P. Purification of a new cytochrome P-450 from human liver microsomes. Biochim. Biophys. Acta. 1985; 860: 364–370
   Web of Science ®Google Scholar
• Laemmli U.K. Cleavage of structural proteins during the assembly of head of bacteriophage T4. Nature (Lond.) 1970; 227: 680–685
   PubMed Web of Science ®Google Scholar
• Guengerich F.P., Dannan G.A., Wright S.T., Martin M.V., Kaminyky L.S. Purification and characterisation of liver microsomal cytochromes P-450: Electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isoenzymes isolated from rats treated with phenobarbital or β-naphtoflavone. Biochemistry 1982; 21: 6019–6030
   PubMed Web of Science ®Google Scholar
• Massaad L., De Waziers I., Ribrag V., Janot F., Leaune P.H., Morizet J., Gouyette A., Chabot G.G. Comparison of mouse and human colon tumors with regard to phase I and phase II drug-metabolizing enzyme systems. Cancer Res. 1992; 52: 6567–6515
   PubMed Web of Science ®Google Scholar
• Nebert D.W., Nelson D.R., Coon M.J., Estarbrook R.W., Feyereisen R., Fujii-Kuriyama Y., Gonzales F.J., Guengerich F.P., Gunsalus I.C., Johnson E.F., Loper J.C., Sato R., Waterman M.R., Waxmann D.J. The P-450 superfamily: update on new sequences, gene mopping, and recommended nomenclature. DNA und cell Biology 1991; 10: 1–14
   PubMed Web of Science ®Google Scholar
• Yoo J.S.H., Ning S.M., Patten C.J., Yang C.S. Metabolism and activation of N-nitrosodimethylamine by hamster and rat microsomes: comparative study with weanling and adults animals. Cancer Res. 1987; 47: 992–998
   PubMed Web of Science ®Google Scholar
• Beaune P.H., Kremers P., Letawe-Goujon F., Gielm J.E. Monoclonal antibodies against human liver cytochrome P-450. Biochem. Pharmacol. 1985; 34: 3547–3552
   PubMed Web of Science ®Google Scholar
• Shimada T., Misono K.S., Guengerich F.P. Human liver microsomal cytochrome P-450 mephenytoin 4-hydroxylase, a prototype of genetic polymorphism in oxidative metabolism. J. Biol. Chem. 1986; 261: 909–921
   PubMed Web of Science ®Google Scholar
• Beaune P.H., Cresteil T., Flinois J.P., Leroux J.P. Hydrophobic chromatography: A one step method for purification of human liver microsomal epoxide hydrolase. J. Chromatogr. Biomed. Appl. 1988; 426: 169–176
   Web of Science ®Google Scholar
• Habig W.H., Pabst M.J., Jakoby W.B. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 1964; 239: 2379–2385
   PubMedGoogle Scholar
• Akerboom T.P., Sies H. Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples. Methods Enzymol 1981; 77: 373–384
   PubMedGoogle Scholar
• Smith P.K., Krohn R.I., Hermanson G.T., Mallia A.K., Gartner F.H., Provenzano M.D., Fujimoto E.K., Goeke N M., Olson B.J., Klenk D.C. Measurement of protein using bicinchoninic acid. Anal. Biochem. 1985; 150: 76–85
   PubMed Web of Science ®Google Scholar
• Fisher R.I., Stiff P.J. Treatment options for recurrent lymphomas. Sem. Oncol. 1990; 17: 63–67
   PubMed Web of Science ®Google Scholar
• Chabner B.A. Salvage therapy for diffuse large cell lymphoma. Blood 1990; 76: 1267–1268
   PubMed Web of Science ®Google Scholar
• Kaizer H., Stuart R.K., Brookmeyer R., Beschorner W.E., Braine H.G., Bums W.H., Fuller D.J., Korbling MI., Mangan K.F., Saral R., Sensenbrenner L., Shadduck R.K., Shende A.C., Tutschka P.J., Yeager A.M., Zinkham W.H., Colvin O.M., Santos G.W. Autologous bone marrow transplantation in acute leukemia: a phase I study of in vitro treatment of marrow with 4-hydroxyper-oxycyclophosphamide to purge tumor cells. Blood 1985; 65: 1504–1510
   PubMed Web of Science ®Google Scholar
• Kovach J.S., Svingen P.A. Antiproliferative activity of 2-(N, N-bis (2-chloroethyl)-amino)-4-(2-sulfonatoethylthio)-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide cyclohexarnine (ASTA Z 7557, INN Mafosfamide) against human and murine tumor cells. in vitro, Invest, New Drugs 1984; 2: 155–159
   PubMed Web of Science ®Google Scholar
• van Ommen B., Van der Zee A.G.J., Meyer C., van Bladeren P.J., Hollema H., De Vries E.G.E. No role For glutathione S-transferase (GST) in in vivo drug resistance to cisplatinum/cyclophosphamide in ovarian cancer?. Proc. Am. Assoc. Cancer Res. 1992; 33: 463
   Google Scholar
• Mannervik B. The isoenzymes of glutathione S-transferase. Adv. Enzymol. 1985; 57: 357–417
   PubMedGoogle Scholar
• Moscow J.A., Towsend A.J., Cowan K.H. Elevation of pi class glutathione S-transferase activity in human breast cancer cells by transfection of the GST pi gene and its effect on sensitivity to toxins. Mol. Pharmacol. 1989; 36: 22–28
   PubMed Web of Science ®Google Scholar
• Nakagawa K., Saijo N., Tsushida S., Sakai M., Tsunokawa Y., Yokota J., Muramatsu M., Sato K., Terada M., Tew K.D. Glutathione S-transfernse pi as a determinant of drug resistance in transfectant cell lines. J. Biol. Chem. 1990; 265: 4296–4301
   PubMed Web of Science ®Google Scholar
• Jones S.M., Idle J.R., Hirom P.C. Differential expression of glutathione transferases by native and cultured human lymphocytes. Biochem. Pharmacol. 1988; 37: 4586–4590
   PubMed Web of Science ®Google Scholar
• Hall A., Foster S., Proctor S.J., Cattan A.R. Purification and characterisation of a pi class glutathione S-transferase from human leukemic cells. Br. J. Haematol. 1990; 76: 494–500
   PubMed Web of Science ®Google Scholar
• Moss K., Maessow P., Vigh W.S.P., Gall H., Bowen E., Pinedo H.M. Pharmacokinetics and metabolism of epidoxorubicin and doxorubicin in humans. J. Clin. Oncol. 1988; 6: 517–526
   PubMed Web of Science ®Google Scholar