34
Views
16
CrossRef citations to date
0
Altmetric
Original Article

Current Aspects of Drug Therapy in Philadelphia-positive CML: Correlation of Tumor Burden with Survival

&
Pages 161-167 | Received 18 Mar 1996, Published online: 01 Jul 2009

References

  • Griffin J. D., Todd R. F., Ritz J., Nadier L. M., Canellos G. P., Rosenthal D., Gallivon M., Beveridge R. P., Weinstein H., Karp D., Schlossman S. F. Differentiation Patterns in the Blastic Phase of Chronic Myeloid Leukemia. Blood 1983; 61: 85–91
  • Thomas E. D., Clift R. A. Indications for Marrow Transplantation in Chronic Myelogenous Leukemia. Blood 1989; 73: 861–864
  • Armitage J. O. Bone Marrow Transplantation. N. Engl. J. Med. 1994; 330: 827–838
  • Beatty P. G., Anasetti C., Hansen J. A., Longton G. M., Sanders J. E., Martin P. J., Mickelson E. M., Choo S. Y., Petersdorf E. W., Pepe M. S., Applebaum F. R., Bearman S. I., Buckner C. D., Clift R. A., Petersen F. B., Singer J., Stewart P. S., Storb R. F., Sullivan K. M., Tesler M. C., Witherspoon R. P., Thomas E. D. Marrow Transplantation From Unrelated Donors for Treatment of Hematologic Malignancies: Effects of Mismatching for One HLA Locus. Blood 1993; 81: 249–253
  • Kernan N. A., Bartsch G., Ash R. C., Beatty P. G., Champlin R., Filipovich A., Gajewski J., Hansen J. A., Henslee-Downey J., McCullough J., McGlave P., Perkins H. A., Phillips G. L., Sanders J., Stroncek D., Thomas E. D., Blume K. G. Analysis of 462 Transplantations from Unrelated Donors Facilitated by the National Marrow Donor Program. New Engl. J. Med., 328: 593–602
  • Haut A., Abbott W. S., Wintrobe M. M., Cartwright G. E. Busulfan in the Treatment of Chronic Myelocytic Leukemia: the Effect of Long Term Intermittent Therapy. Blood 1961; 17: 1–19
  • Galton D. A. G. Chemotherapy of Chronic Myelocytic Leukemia. Semin. Hematol. 1969; 6: 323–343
  • Müller L., Hehlmann R. 24 Jahre Überlebenszeit bei chronisch myeloischer Leukämie. Klin. Wochenschr. 1987; 65: 673–676
  • Brodsky I., Fuscaldo K. E., Kahn S. B., Conroy J. F. Myeloproliferative Disorders. II. CML: Clonal Evolution and its Role in Management. Leuk. Res. 1979; 3: 379–393
  • Cunningham I., Gee T., Dowling M., Chaganti R., Bailey R., Hopfan S., Bowden L., Turnbull A., Knapper W., Clarkson B. Results of Treatment of Ph1+ Chronic Myelogenous Leukemia with an Intensive Treatment Regimen (L-5 Protocol). Blood 1979; 53: 375–395
  • Goto T., Nishikori M., Arlin Z., Gee T., Kempin S., Burchenal J., Strife A., Wisniewski D., Lambek C., Little C., Jhanwar S., Chaganti R., Clarkson B. Growth Characteristics of Leukemic and Normal Hematopoietic sells in Ph1+ Chronic Myelogenous Leukemia and Effects of Intensive Treatment. Blood 1982; 59: 793–808
  • Sharp J. C., Joyner M. V., Wayne A. W., Kemp J., Crofts M., Birch A. D. J., McArthur G., Lai S., Sterndale H., Williams Y. Karyotypic Conversion in Ph-1-positive Chronic Myeloid Leukemia with Combination Chemotherapy. Lancet 1979; 1: 1370–1372
  • Kantarjian H. M., Vellekoop L., McCredie K. B., Keating M. J., Hester J., Smith T., Barlogie B., Trujillo J., Freireich E. J. Intensive Combination Chemotherapy (ROAP 10) and Splenectomy in the Management of Chronic Myelogenous Leukemia. J. Clin. Oncol. 1985; 3: 192–200
  • Kantarjian H. M., Talpaz M., Kurzrock R., Keating M. J., McCredie K. B., Gutterman J., Freireich E. J. Intensive Combination Chemotherapy and Interferons in the Management of Chronic Myelogenous Leukemia. Acta. haemat. 1987; 78((suppl. 1))70–74
  • Hehlmann R. Cytostatic Therapy in Chronic Myelogenous Leukemia: Review and Perspectives. Chronic Myelocytic Leukemia and Interferon, D. Huhn, K. P. Hellriegel, N. Niederle. Springer Verlag, Berlin 1988; 102–112
  • Kennedy B. J. Hydroxyurea Therapy in Chronic Myelogenous Leukemia. Cancer 1972; 29: 1052–1056
  • Bolin R. W., Robinson W. A., Sutherland J., Hamman R. F. Busulfan Versus Hydroxyurea in Long-term Therapy of Chronic Myelogenous Leukemia. Cancer 1982; 50: 1683–1687
  • Rushing D., Goldman A., Gibbs G., Howe R., Kennedy B. J. Hydroxyurea versus Busulfan in the Treatment of Chronic Myelogenous Leukemia. Am. J. Clin. Oncol. (CCT) 1982; 5: 307–313
  • Hehlmann R., Heimpel H., Hasford J., Kolb H. J., Pralle H., Hossfeld D. K., Queiβer W., Löffler H., Heinze B., Georgii A., Wussow Pv., Bartram C. R., Grießhammer M., Bergmann L., Essers U., Falge C., Hochhaus A., Queißer U., Sick C., Meyer P., Schmitz N., Verpoort K., Eimermacher H., Walther F., Westerhausen M., Kleeberg U. R., Heilein A., Käbisch A., Barz C., Zimmermann R., Meuret G., Tichelli A., Berdel W. E., Kanz L., Anger B., TiggesSchmid F. J., Brockhaus W., Zankovich R., Schläfer U., Weißenfels I., Mainzer K., Tobler A., Perker M., Hohnloser J., Messerer D., Thiele J., Buhr T., Ansari H. and the German CML Study Group. (1993) Randomized Comparison of Busulfan and Hydroxyurea in Chronic Myelogenous Leukemia (CML): Prolongation of Survival by Hydroxyurea. Blood, 82: 398–407
  • Talpaz M., McCredie K., Mavligit G. M., Gutterman J. U. Leukocyte Interferon-induced Myeloid Cytoreduction in Chronic Myelogenous Leukemia. Blood 1983; 62: 689–692
  • Talpaz M., Kantarjian H. M., McCredie K., Trujillo J. M., Keating M. J., Gutterman J. U. Hematologic Remission and Cytogenetic Improvement Induced by Recombinant Human Interferon alpha in Chronic Myelogenous Leukemia. N. Engl. J. Med. 1986; 314: 1065–1069
  • Talpaz M., Kantarjian H., Kurzrock R., Trujillo J. M., Gutterman J. U. Interferon Alpha Produces Sustained Cytogenetic Responses in Chronic Myelogenous Leukemia. Ann. Intern. Med. 1991; 114: 532–538
  • Hehlmann R., Heimpel H., Hasford J., Kolb H. J., Pralle H., Hossfeld D. K., Queißer W., Löffler H., Hochhaus A., Heinze B., Georgii A., Bartram C. R., Grießhammer M., Bergmann L., Essers U., Falge C., Queißer U., Meyer P., Schmitz N., Eimermacher H., Walther F., Fett W., Kleeberg U. R., Käbisch A., Nerl C., Zimmermann R., Meuret G., Tichelli A., Kanz L., Tigges F. J., Schmid L., Brockhaus W., Tobler A., Reiter A., Perker M., Emmerich B., Verpoort K., Zankovich R., Wussow P., Prümmer O., Thiele J., Buhr T., Carbonell F., Ansari H., the German CML Study Group. Randomized Comparison of Interferon-alpha with Busulfan and Hydroxyurea in Chronic Myelogenous Leukemia (CML). Blood, 84: 4064–4077
  • Anderson P. K. Conditional Power Calculations as an Aid in Decision whether to Continue a Clinical Trial. Controlled Clin. Trial 1987; 8: 67–74
  • Simon R., Makuch R. W. A Non-parametric Graphical Representation of the Relationship Between Survival and the Occurence of an Event: Application to Responder Versus Non-responder Bias. Stat. Med. 1984; 3: 35
  • Griesshammer M., Hehlmann R., Hochhaus A., Talpaz M., Tura S., Stryckmans P., Allan N. C., Tanzer J., Kolb H. J., Heimpel H. Interferon in Chronic Myelogenous Leukemia. A Workshop Report. Ann. Hematol. 1993; 67: 101–106
  • The Italian Cooperative Study Group on Chronic Myeloid Leukemia. Interferon alfa-2a as Compared with Conventional Chemotherapy for the Treatment of Chronic Myeloid Leukemia. N. Engl. J. Med. 1994; 330: 820–825
  • Allan N. C., Richards S. M., Shepherd P. C. A. UK Medical Research Council Randomized, Multicentre Trial of Interferon-αn1 for Chronic Myeloid Leukaemia is not Confined to Patients with Cytogenetic Response: Improved Survival Irrespective of Cytogenetic Response. Lancet 1995; 345: 1392–1397
  • Kloke O., Niederle N., Qiu J. Y., Moritz T., Nagel-Hiemke M., Opalka B., Seeber S., Becher R. Impact of Interferon Alpha-induced Cytogenetic Improvement on Survival in Chronic Myelogenous Leukaemia. Brit. J. Haematol. 1993; 83: 399–403
  • Ozer H., George S. L., Schiffer C. A., Rao K., Rao P. N., Wurster-Hill D. H., Arthur D. D., Powell B., Gottlieb A., Peterson B. A., Rai K., Testa J. R., LeBeau M., Tantravahi R., Bloomfield C. D. Prolonged Subcutaneous Administration of Recombinant α 2b Interferon in Patients With Previously Untreated Philadelphia Chromosome-Positive Chronic-Phase Chronic Myelogenous Leukemia: Effect on Remission Duration and Survival: Cancer and Leukemia Group B Study 8583. Blood 1993; 82: 2975–2984
  • Kantarjian H. M., Smith T. L., O'Brien S., Beran M., Pierce S., Talpaz M. Prolonged Survival in Chronic Myelogenous Leukemia Following Cytogenetic Response to Alpha Interferon Therapy. Ann. Intern. Med. 1995; 122: 254–261
  • Sokal J. E., Cox E. B., Baccarani M., Tura S., Gomez G. A., Robertson J. E., Tso C. Y., Braun T. J., Clarkson B. D., Cervantes F., Rozman C., the Italian Cooperative CML Study Group. Prognostic Discrimination in “Good-Risk” Chronic Granulocytic Leukemia. Blood, 63: 789–799
  • Hehlmann R., Heimpel H., Hasford J., the German CML Study Group. Randomized Comparison of Interferon alpha, Hydroxyurea and Busulfan in CML. Blood, 85: 3000–3002
  • Mahon F. X., Montastruc M., Faberes C., Reiffers J. Predicting Complete Cytogenetic Response in Chronic Myelogenous Leukemia Patients Treated with Recombinant Interferon α. Blood 1994; 84: 3592–3594
  • Kantarjian H. M., Talpaz M., Keating M. J., Estey E. H., O'Brien S., Beran M., McCredie K. B., Gutterman J., Freireich E. J. Intensive Chemotherapy Induction followed by Interferon-Alpha Maintenance in Patients With Philadelphia Chromosome-Positive Chronic Myelogenous Leukemia. Cancer 1991; 68: 1201–1207
  • Hoyle C., Gray R., Goldman J. Autografting for patients with CML in chronic phase: an update. Brit. J. Haematol. 1994; 86: 76–81
  • Carella A. M., Podesta M., Frassoni F., Raffo M. R., Pollicardo N., Pungolino E., Vimercati R., Sessarego M., Parodi C., Rabitti C., Ferrero R., Benvenuto F., Figari O., Carlier P., Levcasic G., Valbonesi M., Vitale V., Giordano D., Pierluigi D., Nati S., Guerraçio A., Rosso C., Saglio G. Collection of ‘normal’ blood repopulating cells during early hemopoietic recovery after intensive conventional chemotherapy in chronic myelogenous leukemia. Bone Marrow Transplantation 1993; 12: 267–271
  • Carella A. M., Frassoni F., Pollicardo N., Pungolino E., Ferrero R., Vasallo F., Soracco M., Giordano D., Figari O., Benvenuto F., Florio G., Carlier P., Valbonesi M. Philadelphia-chromosome-negative peripheral blood stem cells can be mobilized in the early phase of recovery after a myelosuppressive chemotherapy in Philadelphia-chromosome-positive acute lymphoblastic leukemia. Brit. J. Haematol. 1995; 89: 535–538
  • Simonsson B., öberg G., Killander A., Björeman M., Björkholm M., Gahrton G., Hast R., Turesson I., Udén A. M., Malm C., Vilén L., Wahlin A., Löfvenberg E., Carneskog J., Westin J. Intensive Treatment in Order to Minimize the Ph-Positive Clone in Chronic Myelogenic Leukemia. Stem Cells 1993; 11((suppl 3))73–76
  • McGlave P. B., De Fabritiis P., Deisseroth A., Goldman J., Barnett M., Reiffers J., Simonsson B., Carella A., Aeppli D. Autologous transplants for chronic myelogenous leukaemia: results from eight transplant groups. Lancet. 1994; 343: 1486–1488
  • Gale R. P., Baccarani M., Horowitz M. M., Zhang M. J. Is the Course of Chronic Myelogenous Leukemia Affected by Bone Marrow Transplantation? An Analysis in Patients Relapsing after Bone Marrow Transplants. Blood 1993; 92(Suppl. 1)167a
  • Horowitz M. Annual Meeting of the German CML Study Group, Wachenburg/Weinheim, June 23/24, 1995

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.