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Original Article

Treatment of Relapsed Adult Acute Lymphoblastic Leukemia with Fludarabine and Cytosine Arabinoside Followed by Granulocyte Colony-Stimulating Factor (FLAG-GCSF)

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Pages 579-583 | Received 14 Jul 1996, Published online: 01 Jul 2009

References

  • Hoelzer D., Thiel E., Loffler H., Buchner T., Ganser A., Heil G., Koch P., Freund M., Diedrich H., Ruhl H., Mashmeyer G., Lipp T., Nowrousian M. R., Burkerl M., Gerecke D., Pralle H., Muller U., Lunscken Ch., Fulle H., Ho A. D., Kuchler R., Bush F. W., Shneider W., Gorg Ch., Emmerich B., Brauman D., Vaupel H. A., Von Paleske A., Bartels H., Neiss Amesserer D. Prognostic factors in multicenter study for treatment of acute lymphoblastic leukemia in adults. Blood 1988; 71: 123–33
  • Linker C. A., Levitt L. J., O'Donnell M. Improved results of treatment of adult acute lymphoblastic leukemia. Blood 1987; 69: 1242–8
  • Suki S., Kantarjian H., Gandhi V., Estey E., O'Brien S., Bera M., Rios M. B., Plunkett W., Keating M. Fludarabine and Cytosine Arabinoside in the treatment of refractory or relapsed acute Lymphocitic leukemia. Cancer 1993; 72: 2155–2160
  • Hoelzer D., Gale R. P. Acute lymphoblastic leukemia in adults: recent progress, future directions. Semin, Hematol. 1987; 24: 27–39
  • Freund M., Diedrich H., Ganser A. Treatment of relapsed or refractory adult acute lymphoblastic leukemia. Cancer 1992; 69: 709–716
  • Freund M., De Boden, Diedrich H. Treatment of relapsed acute lymphocytic leukemia in adults. Haematology and Blood, J. Buchner, G. Schellong, W. Hiddeman, J. Ritter. Springer‐Verlag, Munster, FRG 1990; 432–436
  • Jacobs A. D., Gale R. P. Recent advances in the biology and treatment of acute lymphoblastic leukemia in adults. New Eng. J. Med. 1984; 311: 1219–1231
  • Mathé G., Misset J. L., De Vassal F. Phase II clinical trial with vindesine for remission induction in acute leukemia, blastic crisis of chronic myeloid leukemia, lymphosarcoma and Hodgkins disease: absence of cross‐resistance with vincristine. Cane. Treat. Reports. 1978; 62: 805–809
  • Kantarjian H. M., Walters R. L., Keating M. J., Estey E. H., O'Brien S., Schachner J., McCredie K. B., Freireiches J. Miloxantrone and high dose Cytosine arabinoside for the treatment of acute lymphocytic leukemia. Cancer 1990; 65: 5–8
  • Arlin Z. A., Felman E., Sandford K., Ahmed T., Mittelman A., Savona S., Ascensao J., Baskind P., Sullivan P., Fuhr H. G., Mertelsmann R. Amsacrine with high dose cytarabine is highly effective therapy for refractory and relapsed acute lymphoblastic leukemia in adults. Blood 1988; 72: 433–435
  • Kantarjian H. M., Estey E. H., O'Brien S., Anaissie E., Beran M., Rios M. B., Keating M. J., Gutterman J. Intensive chemotherapy with mitoxantrone and high‐dose cytosine arabinoside followed by granulocyte‐macrophage stimulating factor in the treatment of patients with acute myphocytic leukemia. Blood 1992; 79: 876–881
  • Gandhy V., Kemena A., Keating M. J. Fludarabine potentiates arabinosyl‐cytosine metabolism in lymphocites of patients with chronic lymphocytic leukemia. Cancer. Res. 1992; 52: 897–903
  • Antman K. S., Griffin J. D., Elias A., Socinsky M. A., Ryan L., Cannistra S. A., Oette D., Whitley M., Frei E., III, Schnipper L. E. Effect of recombinant human granulo‐cyte‐macrophage colony stimulating factor on chemotherapy‐induced myelosuppression. N. Engl. J. Med. 1988; 319: 593–595
  • Mortsyn G., Campbell L., Souza L. M., Alton N. K., Keech J., Green M., Sheridan W., Metcalf D., Fox R. Effect of granulocyle colony stimulating factor on neutropenia induced by cytoloxic chemotherapy. Lancet 1988; 1: 667–669
  • Nemunaitis J., Singer J. W., Buckner C. D., Hill R., Storb R., Thomas E. D., Applebaum F. R. Use of recombinant human granulocyte‐macrophage colony‐stimulating factor in autologus marrow transplantation for mymphoid malignancies. Blood 1988; 72: 834–836
  • Gianni A. M., Bregni M., Siena S., Orazi A., Stern A. C., Gandola L., Bonadonna G. Recombinant human granuloeyte‐macrophage colony‐stimulating factor reduces hematologic toxicity and widens clinical applicability of high dose cyclophosphamide treatment in breast cancer and non‐Hodgkins. Lymphoma. J. Clin. Oncol. 1990; 8: 768–778
  • Ohno R., Tomonaga M., Kobayashi T. Effect of granulocyte colony—stimulating factor after intensive induction chemotherapy in relapsed or refractory acute leukemia. N. Engl. J. Med. 1990; 323: 871–877
  • Scherre R., Geissler K., Kyrle P. A. Granulocyte colony stimulating factor (G‐CSF) as an adjuction to induction chemotherapy of adult acute lymphoblastic leukemia (ALL). Ann. Hematol. 1993; 66: 283–289
  • Warrel R., Berman E. Phase I and II study of fludarabine phosphate in leukemia: therapeutic efficacy with delayed central nervous system toxicity. J. Clin. Oncol. 1986; 4: 74–79
  • Chun H. G., Leyland‐Jones B. R., Caryk S. M., Hoth D. F. Central nervous system toxicity of fludarabine phosphate. Cancer Treat. Rep. 1986; 70: 1225–1228
  • Ibayashi Y., Ohyama H., Hashimoto Y., Sakatani K., Morimoto S., Takahashi H., Shibata K., Kashiwabara S., Tanabe S., Hashi K. A case report of interstitial pneumonia caused by granulocyte colony‐stimulating factor. No Shinkei Geka. 1994; 22: 169–174
  • Kane G. C., McMichhael A. J., Patrick H., Erslev J. Pulmonary toxicity and acute respiratory failure associated with fludarabine monophosphate. Respiratory Medicine 1992; 86: 261–263
  • Yang L. Y., Trujillo J. M., Keating M. J. Effect of fludarabine on the tumoricidal synergy produced by the combination of arabinosylcytosine and cisplatin in human LoVo colon carcinoma cells. Proc. Am. Assoc. Cancer Res. 1992; 33: 443
  • Robertson L. E., Kantarjian H., O'Brien S. Cisplatin. fludarabine and ara‐C: A regimen for advanced refractory chronic lymphocytic leukemia. Proc. Am. Assoc. Cancer Res. 1993; 34: 347
  • Keating M. J., O'Brien S., Robertson L. E., Kantarjian H., Dimopoulos M., McLaughlin P., Cabanillas F., Gregoire V., Yang L. Y., Gandhi V., Estey E., Plunkett W. New initiatives with fludarabine monophosphate in hematologic malignancies. Semin. Oncol. 1993; 5: 13–20

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