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Review Article

Autonomous and Interleukin-2-Responsive Growth of Leukemic Cells in Adult T-cell Leukemia (ATL): A Review of the Clinical Significance and Molecular Basis of ATL Cell Growth

Pages 479-487 | Accepted 10 Oct 1996, Published online: 01 Jul 2009

References

  • Yoshida M., Miyoshi I., Hinuma Y. Isolation and characterization of retrovirus (ATLV) from cell lines of adult T cell leukemia and its implication in the disease. Proc Natl Acad Sci USA 1982; 79: 2031–5
  • Seiki M., Hattori S., Hirayama Y., Yoshida M. Human adult T cell leukemia virus: Complete nucleotide sequence of the provirus genome integrated in leukemia cell DNA. Proc Natl Acad Sci USA 1983; 80: 3618–22
  • Seiki M., Eddy R., Shows T. B., Yoshida M. Nonspecific integration of the HTLV provirus genome into adult T-cell leukaemia cells. Nature 1984; 309: 640–2
  • Morgan D. A., Ruscetti F. W., Gallo R. Selective in vitro growth of T-lymphocytes from normal human bone marrows. Science 1976; 193: 1007–8
  • De Larco J. E., Todaro G. J. Growth factors from murine sarcoma virus-transformed cells. Proc Natl Acad Sci USA 1978; 75: 4001–5
  • Gordon J., Ley S. C., Melamed M. D., English L. S., Hughes-Jones N. C. Immortalized B lymphocytes produce cell growth factor. Nature 1984; 310: 145–7
  • Duprez V. G., Lenoir G., Dautry-Varsat A. Autocrine growth stimulation of a human T-cell lymphoma cell line by interleukin 2. Proc Natl Acad Sci USA 1985; 82: 6932–6
  • Arya S. K., Wong-Staal F., Gallo R. C. T-cell growth factor gene: lack of expression in human T-cell leukemia-lymphoma virus-infected cells. Science 1984; 223: 1086–7
  • Yodoi J., Uchiyama T., Maeda M. T-cell growth factor receptor in adult T-cell leukemia (letter). Blood 1983; 62: 509–11
  • Uchiyama T., Hori T., Tsudo M., et al. Interleukin-2 receptor (Tac antigen) expressed on adult T cell leukemia cells. J Clin Invest 1985; 76: 446–53
  • Arima N., Daitoku Y., Ohgaki S., et al. Autocrine growth of interleukin 2-producing leukemic cells in a patient with adult T cell leukemia. Blood 1986; 68: 779–82
  • Arima N., Daitoku Y., Yamamoto Y., et al. Heterogeneity in response to interleukin 2 and interleukin 2-producing ability of adult T cell leukemic cells. J Immunaal 1987; 138: 3069–74
  • Gordon J., Aman P., Rosen A., Ernberg I., Ehlin-Henriksson B., Klein G. Capacity of B-lympho-cytic lines of diverse tumor origin to produce and respond to B-cell growth factors: a progression model for B-cell lym-phomagenesis. Int J Cancer 1985; 35: 251–6
  • Schrader J. W. Role of a single haemopoietic growth factor in multiple proliferative disorders of haemopoietic and related cells. Lancet 1984; 2(8395)133–6
  • Tokunaga M., Tokudome T., Hasui K., Sato E. Immunohistopathology of Adult T-cell Leukemia/Lymphoma. Proc ICML, Kyoto, Hanaoka, Watanabe. Field and Wood, Philadelphia, PA. 1989; 117
  • Noma T., Nakamura T., Maeda M., et al. Interleukin 1 alpha mRNA in virus-transformed T and B cells. Biochem Biophys Res Commun 1986; 139: 353–60
  • Wano Y., Hattori T., Matsuoka M., et al. Interleukin 1 gene expression in adult T cell leukemia. J Clin Invest 1987; 80: 911–6
  • Yamashita U., Shirakawa F., Nakamura H. Production of interleukin 1 by adult T cell leukemia (ATL) cell lines. J Immunol 1987; 138: 3284–9
  • Kodaka T., Uchiyama T., Umadome H., Uchino H. Expression of cytokine mRNA in leukemic cells from adult T cell leukemia patients. Jpn J Cancer Res 1989; 80: 531–6
  • Azuma C., Tanabe T., Konishi M., et al. Cloning of cDNA for human T-cell replacing factor (interleukin-5) and comparison with the murine homologue. Nuclei Acids Res 1986; 25: 9146–58
  • Lal R. B., Rudolph D. L. Constitutive production of interleukin-6 and tumor necrosis factor-alpha from spontaneously proliferating T cells in patients with human T-cell lymphotropic virus type-I/II. Blood 1991; 78: 571–4
  • Srivastava M. D., Srivastava R., Srivastava B. I. Constitutive production of interleukin-8 (IL-8) by normal and malignant human B cells and other cell types. Leuk Res 1993; 17: 1063–1069
  • Burton J. D., Bamford R. N., Peters C., et al. A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells. Proc Natl Acad Sci USA 1994; 91: 4935–4939
  • Niitsu Y., Urushizaki Y., Koshida Y., et al. Expression of TGF-beta gene in adult T cell leukemia. Blood 1988; 71: 263–266
  • Tschachler E., Robert-Guroff M., Gallo R. C., Reitz M. S., Jr. Human T-lymphotropic virus I-infected T cells constitutively express lymphotoxin in vitro. Blood 1989; 73: 194–201
  • Kawasaki C., Okamura S., Omori F., et al. Both granulocyte-macrophag colony-stimulating factor and mono-cytic colony-stimulating factor are produced by the human T-cell line HUT 102. Exp Hematol 1990; 18: 1090–1093
  • Honda S., Yamaguchi K., Miyake Y., et al. Production of parathyroid hormone-related protein in adult T-cell leukemia cells. Jpn J Cancer Res 1988; 79: 1264–1268
  • Noma T., Nakakubo H., Sugita M., et al. Expression of different combinations of interleukins by human T cell leukemic cell lines that are clonally related. J Exp Med 1989; 169: 1853–1858
  • Farrar J. J., Mizel S. B., Fuller-Farrar J., Farrar W. L., Hilfiker M. L. Macrophage-independent activation of helper T cells. I. Production of interleukin 2. J Immunol 1980; 125: 793–798
  • Arima N., Daitoku Y., Hidaka S., et al. Interleukin-2 production by primary adult T cell leukemia tumor cells is macrophage dependent. Am J Hematol 1992; 41: 258–263
  • Matsushita K., Arima N., Fujiyoshi T., et al. Interleukin-2-mediated growth of leukemic cells in lymph nodes of patients with adult T-cell leukernia/lymphoma. Leukemia Res 1996; 20: 135–141
  • Imada K., Takaori-Kondo A., Akagi T., et al. Tumorigenicity of human T-cell leukemia virus type I-infected cell lines in severe combined immunodeficient mice and characterization of the cells proliferating in vivo. Blood 1995; 86: 2350–2357
  • Kawano F., Yamaguchi K., Nishimura H., Tsuda H., Takatsuki K. Variation in the clinical courses of adult T-cell leukemia. Cancer 1985; 55: 851–856
  • Shimoyama M. Diagnostic criteria and classification of clinical subtypes of adult T-cell leukemia-lymphoma. Bri J Haematol 1991; 79: 428–437, members of the Lymphoma Study Group
  • Arima N., Hidaka S., Fujiwara H., et al. Relation of autonomous and interleukin-2-responsive growth of leukemic cells to survival in adult T-cell leukemia. Blood 1996; 87: 2900–2904
  • Lowenberg B., Van Putten W. L., Touw I. P., Delwel R., Santini V. Autonomous proliferation of leukemic cells in vitro as a determinant of prognosis in adult acute myeloid leukemia. N Engl J Med 1993; 328: 614–619
  • Hunter A. E., Rogers S. Y., Roberts I. A., Barrett A. J., Russell N. Autonomous growth of blast cells is associated with reduced survival in acute myeloblastic leukemia. Blood 1993; 82: 899–903
  • Preisler H. D., Raza A., Kukla C., Larson R., Goldberg J., Bowman G. Interleukin-1 B expression and treatment outcome in acute myelogenous leukemia (letter). Blood 1991; 78: 849–850
  • Bradbury D., Rogers S., Reilly I. A., Kozlowski R., Russell N. H. Role of autocine and paracrine production of granulocyte-macrophage colony stimulating factor and interleukin-lβ in the autonomous growth of acute myueloblas-tic leukemia cells-studies using purifgied CD34-positive cells. Leukemia 1992; 6: 562–566
  • Tsuda H., Huang R. W., Takatsuki K. Interleukin-2 prevents programmed cell death in adult T-cell leukemia cells. Jpn J Cancer Res 1993; 84: 431–437
  • Shirakawa F., Tanaka Y., Oda S., Eto S., Yamashita U. Autocrine stimulation of interleukin 1 alpha in the growth of adult human T-cell leukemia cells. Cancer Res 1989; 49: 1143–1147
  • Uchiyama T., Kamio M., Kodaka T., et al. Leukemic cells from some adult T-cell leukemia patients proliferate in response to interleukin-4. Blood 1988; 72: 1182–1186
  • Grabstein K. H., Eisenman J., Shanebeck K., et al. Cloning of a T cell growth factor that interacts with the b chain of the interleukin-2 receptor. Science 1994; 264: 965–968
  • Souza L. M., Boone T. C., Gabrilove J. C., et al. Recombinant human G-CSF: effect on normal and leukemic myeloid cells. Science 1986; 232: 61–65
  • Berdel W. E., Riedl S. R., Steinhauser G., Witon E. F. Various human hematopoietic growth factor (inter-leukin-3, GM-CSF, G-CSF) stimulate clonal growth of non-hematopoietic tumor cells. Blood 1989; 73: 7380–7383
  • Watari K., Asano S., Shirafuji N., et al. Serum granulocyte colony-stimulating factor levels in healthy volunteers and patients with various disorders estimated by enzyme immuno-assay. Blood 1989; 73: 117–122
  • Kawakami M., Tsutsumi H., Kumakawa T., et al. Levels of serum granulocyte colony-stimulating factor in patients with infections. Blood 1990; 76: 1962–7
  • Sodroski J., Rosen C., Goh W. C., Haseltine W. A transcriptional activator protein encoded by the x-lor region of human T-cell leukemia virus. Science 1985; 228: 1430–1434
  • Siekevitz M., Feinberg M. B., Holbrook N., Wong-Staal F., Greene W. C. Activation of interleukin-2 and interleukin-2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, Type I. Proc Natl Acad Sci USA 1987; 84: 5389–5393
  • Nirner S. D., Gasson J. C., Hu K., et al. Activation of the GM-CSF promoter by HTLV-I and -II Tax proteins. Oncogene 1989; 4: 671–676
  • Fujii M., Sassone-Corsi P., Verma I. M. c-fos promoter transactivation by the tax, protein of human T-cell leukemia virus type I. Proc Natl Acad Sci USA 1988; 85: 8526–8530
  • Jeang K. T., Boros I., Brady J., Radonovich M., Khoury G. Characterization of cellular factors that interact with the human T-cell leukemia virus type I p40x-responsive 21 base-pair sequence. J Viol 1988; 62: 4499–4509
  • Ballard D. W., Bohnlein E., Lowental J. W., et al. HTLV-I Tax induces cellular proteins that activate the kB element in the IL-2 receptor-rr gene. Science 1988; 241: 1652–1655
  • Leung K., Nabel G. J. HTLV-I transactivator induces interleukin-2 receptor expression through and NF-kB-like factor. Nature 1988; 33: 776–778
  • Maruyama M., Shibuya H., Harada H., et al. Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-I encloded p40x and T3/Ti complex triggering. Cell 1987; 48: 343–350
  • Migone T-S., Lin J-X., Cereseto A., et al. Constitutively activated Jak-Stat pathway in T cells transformed with HTLV-I. Science 1995; 269: 79–81
  • Sherr C. J., Roberts J. M. Inhibitions of mammalian G1 cyclin-dependent kinase. Genes & Dev 1994; 9: 1149–1163
  • Yokota J., Wada M., Shimosato Y., Terada M., Sugimura T. Loss of heterozygosity on chromosomes 3, 13, and 17 in small-cell carcinoma and on chromosome 3 in adenocarcinoma of the lung. Proc Natl Acad Sci USA 1987; 84: 9252–9256
  • Kamb A., Gruis N. A., Weaver-Feldhaus K., et al. A cell cycle regulator potentially involved in genesis of many tumor types. Science 1994; 264: 436–440
  • Nobori T., Miura K., Wu D. J., Lois A., Takabayashi K., Carson D. A. Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature 1994; 386: 753–756
  • Sakashita A., Hattori T., Miller C. W., et al. Mutations of the p53 gene in adult T-cell leukemia. Blood 1992; 79: 477–480
  • Hatta Y., Hirama T., Miller C. W., et al. Homozygous deletions of the p15 (MTS2) and p16 (CDKN2/MTSl) genes in adult T-cell leukemia. Blood 1995; 85: 2699–2704
  • Jeang K. T., Widen S. G., Semmes O. J., Wilson S. H. HTLV-I trans-activator protein, tax, is a trans-repressor of the human β-polymerase gene. Science 1990; 247: 1082–4
  • Yokota J., Sugimura T. Multiple steps in carcino-genesis involving alterations of multiple tumor suppressor genes. FASEB J 1993; 7: 920–5
  • Okamoto T., Ohno Y., Tsugane S., et al. Multistep carcinogenesis model for adult T-cell leukemia. Jpn J Cancer Res 1989; 80: 191–5

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