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Original Article

Amplification of third-Complementary-Determining-Region (CDR-III) of heavy chain immunoglobulin gene (IgH) in one hundred adult acute leukemias

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Pages 131-139 | Received 26 Sep 1996, Published online: 05 Aug 2009

References

  • Van Dongen J. J. M., Wolvers Tettero I. L.M. Analysis of immunoglobulin and T-cell receptor genes. Part I: Basic and technical aspects. Clin. Chim. Acta 1991; 198: 1–91
  • Tonegawa S. S. Somatic generation of antibody diversity. Nature 1983; 302: 575–581
  • Alt F. W., Blackwell T. K., DePinho R. A., Reth M. G., Yancopoulos G. D. Regulation of genome rearrangement events during lymphocyte differentiation. Immunology Reviews 1986; 89: 5–29
  • Yamada M., Hudson S., Tournay O., Bittenbender S., Shane S. S., Lange B., Tsujimoto Y., Caton A. J., Rovera G. Detection of minimal disease in hematopoietic malignancies of the B-cell lineage by using third-complementarity-determining region (CDR-III)-specific probes. Proc. Natl. Acad. Sci. USA 1989; 86: 5123–5127
  • Ravetch J. V., Slebenlist U., Korsmeyer S., Waldman T., Leder P. Structure of the human immunoglobulin, u locus: characterization of embryonic and rearranged J and D genes. Cell 1981; 27: 583–591
  • Wright J. J., Poplack D. G., Bakshi A., Reaman G., Cole D., Jensen J. P., Korsmeyer S. J. Gene rearrangement as markers of clonal variation and minimal residual disease in acute lymphoblastic leukemia. J. Clin. Oncol 1987; 5: 735–741
  • Brisco M. J., Tan L. W., Orsborn A. M., Morley A. A. Development of a highly sensitive assay, based on the polymerase chain reaction, for rare B-lymphocyte clones in a polyclonal population. Br. J. Haematol 1990; 75: 163–167
  • Bregni M., Siena S., Neri A., Bassan R., Barbui T., Delia D., Bonadonna G., Dalla Favera R., Gianni A. M. Minimal residual disease in acute lymphoblastic leukemia detected by immune selection and gene rearrangement analysis. J. Clin. Oncol 1989; 7: 338–343
  • Campana D., Coustan-Smith E., Janossy G. The immunological detection of minimal residual disease in acute leukaemia. Blood 1990; 76: 163–171
  • Chessells J. M. Acute leukaemia in children. Clinics in Haematology 1990; 15: 727–753
  • Crescenzi M., Seto M., Herzig G. P., Weiss P. D., Griffith R. C., Korsmeyer S. J. Thermostable DNA polymerase chain amplification of t(14:18) chromosome breakpoints and detection of minimal residual disease. Proc. Natl. Acad. Sci. USA 1988; 85: 4869–4873
  • d'Auriol L., Macintyre E., Galibert F., Sigaux F. In vitro amplification of T-cell gene rearrangements: a new tool for the assessment of minimal residual disease in acute lymphoblastic leukaemias. Leukaemia 1989; 3: 155–158
  • Campana D., Pui C. H. Detection of minimal residual disease in acute leukemia: methodologic advances and clinical significance. Blood 1995; 85: 1416–1434
  • Deane M., Norton J. D. Immunoglobulin gene “fingerprinting”: an approach to analysis of B lymphoid clonality in lymphoroliferative disorders. Br. J. Haematol 1991; 77: 274–281
  • Yamada M., Wasserman R., Lange B., Reichard B. A., Womer R. B., Rovera G. F. Minimal residual disease in childhood B- lineage lymphoblastic leukemia. N. Eng. J. Med 1990; 323: 448–454
  • Tomlison I. M., Walter G., Marks J. D., Llewelyn M. B., Winter G. The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops. J. Mol. Biol 1993; 227: 776–798
  • Clearly M. L., Smith S. D., Sklar J. Cloning and structural analysis of cDNAs from bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation. Cell 1986; 47: 19–28
  • Leiber M. R. The mechanism of V(D)J recombination: a balance of diversity, specificity, and stability. Cell 1992; 70: 873
  • Clearly M. L., Meeker T. C., Levy S., Lee E., Trela M., Sklar J., Levy R. Clustering of extensive somatic mutations in the variable region of an immunoglobulin heavy chain gene from a human B cell lymphoma. Cell 1986; 44: 97–106
  • Foon K. A., Todd R. F. Immunological classification of leukemia and lymphoma. Blood 1986; 68: 1–31
  • Martinelli G., Gasparini P., Ambrosetti A., Battista R., Perona G., Pignatti P. F. Molecular genetic analysis of bcr breakpoint in Philadelphia chromosome rearrangements and correlation with prognosis and age of chronic myelogenus leukaemia patients. Genetics of Hematological Disorders. Publishing Corporation., Hemisphere Washington, D.C. 1990; 185–193
  • Martinelli G., Zaccaria A., Farabegoli P., Buzzi M., Testoni N., Bragliani M., Panzica G., Tura S. Structural organization of BCR-ABL gene in chronic phase and blast transformation in chronic myeloid leukemia patients. Leuk. Lymph 1993; 11: 51–56
  • Nizet Y., Martiat P., Vaerman J. L., Philippe M., Wildmann C., Staelens J. P., Cornu G., Ferrant A., Michaux J. L., Sokal G. Follow-up of residual disease (MRD) in B lineage acute leukaemias using a simplified PCR strategy: evolution of MRD rather than its detection is correlated with clinical outcome. Br. J. Haematol 1991; 79: 205–210
  • Billadeau D., Blackstadt M., Greipp P., Kyle R. A., Oken M. M., Kay N., Ness B. Analysis of B-lymphoid malignancies using allele-specific polymerase chain reaction: a technique for sequential quantitation of residual disease. Blood 1991; 78: 3021–3029
  • Deane M., Norton J. D. Detection of immunoglobulin gene rearrangement in B lymphoid malignancies by polymerase chain reaction gene amplification. Br. J. Haematol 1990a; 74: 251–256
  • Bartram C. R. Detection of minimal residual leukemia by the polymerase chain reaction: potential implications for therapy. Clin. Chim. Acta 1993; 217: 75–83
  • Beishuizen A., Haehlen K., Hagemeijer A., Verhoeven M. A. J., Hooijkaas H., Adriaansen H. J., Wolvers-Tettero I. L. M., Van Wering E. R., Van Dongen J. J.M. Multiple rearranged immunoglobulin genes in childhood acute lymphoblastic leukemia of precursor-B-cell origin. Leukemia 1991; 5: 657–667
  • Bird J., Galili N., Link M., Stites D., Sklar J. Continuing rearrangement but absence of somatic hypermutation in immunoglobulin genes of human B cell precursor leukemia. J. Exp. Med 1988; 168: 229–245

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