Aberrant DNA Methylation of Genomic Regions Translocated in Myeloid Malignancies

References

• Adams R. L. P. DNA Methylation: The effect of minor bases on DNA-protein interactions. Biochem J 1990; 265: 309–320
   PubMed Web of Science ®Google Scholar
• Jones P. A., Buckley J. D. The role of DNA methylation in cancer. Adv Cancer Res 1990; 54: 1
   PubMedGoogle Scholar
• Riggs A. D. DNA methylation and late replication probably aid cell memory, and type I DNA reeling could aid chromosome folding and enhancer function. Phil Trans R Soc Lond B 1990; 326: 285–297
   PubMed Web of Science ®Google Scholar
• Bird A. The essentials of DNA methyalation. Cell 1992; 70: 5–8
   PubMed Web of Science ®Google Scholar
• Weissbach A. Eukaryotic DNA methylation and demethylation-sequence and strand specificity. Bioessays 1987; 7: 243
   PubMed Web of Science ®Google Scholar
• Weissbach A., Ward C., Bolden A. Eukaryotic DNA methylation and gene expression. Current Topics Cell Reg, 30: 1–21
   PubMedGoogle Scholar
• Mather E., Perry R. Methylation status and DNasel sensitivity of immunoglobulin genes: changes associated with rearrangement. Proc Natl Acad Sci USA 1983; 80: 4689–4693
   PubMed Web of Science ®Google Scholar
• Storb U., Arp B. Methylation patterns of immunoglobulin genes in lymphoid cells: correlation of expression and differentiation with undermethylation. Proc Natl Acad Sci USA 1983; 80: 6642–6646
   PubMed Web of Science ®Google Scholar
• Persiani D., Seising E. DNasel sensitivity of immunoglobulin light chain genes in Ableson murine leukemia virus transformed pre-B cell lines. Nucl Acids Res 1989; 17: 5339–5348
   PubMed Web of Science ®Google Scholar
• Foroni L., Boehm T., Lampert F., Kaneko Y., Raimondi S., Rabbits T. Multiple methylation free islands flank a small breakpoint cluster region on 11p13 in the t(11;14)(p13;q11) translocation. Genes Chroma Cancer 1990; 1: 301–309
   PubMed Web of Science ®Google Scholar
• Tauchi T., Ohyashiki J., Ohyashiki K., et al. Methylation status of T-cell receptor β chain gene in B precursor acute lymphoblastic leukemia: correlation with hypomethylation and gene rearrangement. Cancer Res 1991; 51: 2917–2921
   PubMed Web of Science ®Google Scholar
• Ohyashiki J., Ohyashiki K., Kawakubo K., et al. T-cell recptor β chain gene rearrangement in acute myeloid leukemia always occurs at the allele that contains under-methylated Jbl region 1. Cancer Res 1992; 52: 6598–6602
   PubMed Web of Science ®Google Scholar
• Hsieh C., Lieber M. CpG methylated minichromosomes become inaccessible for V(D)J recombination after undergoing replication. EMBO J 1992; 11: 315–325
   PubMed Web of Science ®Google Scholar
• Hagerman P. J. Pyrimidine 5-methyl groups influence the magnitude of DNA curvature. Biochemistry 1990; 29: 1980–1983
   PubMed Web of Science ®Google Scholar
• Zacharias W., Jaworski A., Wells R. D. Cytosine methylation enhances Z-DNA formation in vivo. J Bacteriol 1990; 172: 3278–3283
   PubMed Web of Science ®Google Scholar
• Litz C. E., Goldfarb A. N., Stickler J. G., Brunning R. D. Presence of cell lineage specific hypomethylated sites in the major breakpoint cluster region. Cancer Res 1990; 50: 4984–4990
   PubMed Web of Science ®Google Scholar
• Litz C. E., McClure J. S., Coad J. E., Goldfarb A. N., Brunning R. D. Methylation status of the major breakpoint cluster region (M-bcr) in Philadelphia chromosome negative leukemias. Leukemia 1992; 6: 35–41
   PubMed Web of Science ®Google Scholar
• Litz C. E., Vos J. A., Copenhaver C. M. Aberrant methylation of the major breakpoint cluster region in chronic myeloid leukemia. Blood 1996; 88: 2241–2249
   PubMed Web of Science ®Google Scholar
• Etzell J., Litz C. E. Aberrant methylation of the RARA gene in acute promyelocytic leukemia. 1997, Manuscript in preparation).
   Google Scholar
• Nowell P., Hungerford D. A minute chromsome in human chronic granulocytic leukemia. Science 1960; 132: 1497
   Web of Science ®Google Scholar
• Rowley J. D. A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining. Nature 1973; 243: 290–293
   PubMed Web of Science ®Google Scholar
• Groffen J., Stephenson J. R., Heisterkamp N., De Klein A., Bartram C. R., Grosveld G. Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22. Cell 1984; 36: 93–99
   PubMed Web of Science ®Google Scholar
• Kurzrock R., Gutterman J. U., Talpaz M. The molecular genetics of Philadelphia chromosome-positive leukemias. N Engl J Med 1988; 319: 990–998
   PubMed Web of Science ®Google Scholar
• Heisterkamp N., Stam K., Groffen J. Structural organization of the bcr gene and its role in the Ph' translocation. Nature 1985; 315: 758–761
   PubMed Web of Science ®Google Scholar
• Shtivelman E., Lifshitz B., Gale R. P., Canaani E. Fused transcript of abl and bcr genes in chronic myelogenous leukaemia. Nature 1985; 315: 550–554
   PubMed Web of Science ®Google Scholar
• Daley G. Q., Van E. R., Baltimore D. Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome. Science 1990; 247: 824–30
   PubMed Web of Science ®Google Scholar
• Saglio G., Guerrasio A., Rosso C., ZaccarÍA A., Tassinari A., Serra A., Rege-Cambrin G., Mazza U., Gavosto F. New type of BCR/abl junction in Philadelphia chromosome-positive chronic myelogenous leukemia. Blood 1990; 76: 1819–1824
   PubMed Web of Science ®Google Scholar
• Groffen J., Stephenson J. R., Heisterkamp N., Deklein A., Bartram C. R., Grosveld G. Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22. Cell 1984; 36: 93–99
   PubMed Web of Science ®Google Scholar
• Schaefer-Rego K., Dudek H., Popenoe D., Arlin Z., Mears J. G., Bank A., Leibowitz D. CML patients in blast crisis have breakpoints localized to a specific region of the BCR. Blood 1987; 70: 448–455
   PubMed Web of Science ®Google Scholar
• Benn P., Grossman A., Soper L., Hall B., Silver R., Coleman M., Arlin Z., Gascon P. Limited heterogeneity of chromosome 22 breakpoints in chronic myeloid leukemia (CML). Am J Hum Genet 1988; 43: A75
   PubMedGoogle Scholar
• Torelli G., Selleri L., Giovanni E., Narni F., Colo A., Zucchini P., Donelli A., Venturelli D., Torelli U. Molecular study of the Philadelphia translocation in chronic myelogeneous leukemia in different stages of disease. Haematologica 1987; 72: 201–208
   PubMedGoogle Scholar
• Mills K. I., Mackenzie E. D., Birnie G. D. The site of the breakpoint within the bcr is a prognostic factor in Philadelphia positive CML patients. Blood 1988; 72: 1237–1241
   PubMed Web of Science ®Google Scholar
• Shtalrid M., Talpaz M., Kurzrock R., Kantarjian H., Trujillo J., Gutterman J., Yoffe G., Blick M. Analysis of breakpoints within the bcr gene and their correlation with the clinical course of Philadelphia-positive chronic myelogenous leukemia. Blood 1988; 72: 485–490
   PubMed Web of Science ®Google Scholar
• Mills K. I., Sproul A. M., Burnett A. K. Methylation of the major breakpoint cluster region (M-bcr) in Philadelphia chromosome positive CML. Leukemia 1993; 7: 707–711
   PubMed Web of Science ®Google Scholar
• Ohyashiki J., Ohyashiki K., Kawakubo K., Tauchi T., Shimamoto T., Toyama K. The methylation status of the major breakpoint cluster region in human leukemia cells, including Philadelphia chromosome-positive cells, is linked to the lineage of hematopoietic cells. Leukemia 1993; 7: 801–807
   PubMed Web of Science ®Google Scholar