Wilms Tumor Gene (WT1) as a New Marker for the Detection of Minimal Residual Disease in Leukemia

References

• Campana D., Pui C-H. Detection of minimal residual disease in acute leukemia: Methodologic advances and clinical significance. Blood 1995; 85: 1416–1434
   PubMed Web of Science ®Google Scholar
• Gray J. W., Kuo W. L., Liang J., Pinkel D., Van Den Engh G., Trask B., Tkachuk D., Waldman F., Westbrook C. Analytical approaches to detection and characterization of disease-linked chromosome aberrations. Bone Marrow Transplant 1990; 6: 14–19
   PubMed Web of Science ®Google Scholar
• Yamada M., Hudson S., Tournay O., Bittenbender S., Shane S. S., Lange B., Tsujimoto Y., Caton A. J., Rovera G. Detection of minimal disease in haemopoietic malignancies of the B-cell lineage by using third-complementarity-determining region (CDR-III)-specific probes. Proc. Natl. Acad. Sci. U.S.A. 1989; 86: 5123–5127
   PubMed Web of Science ®Google Scholar
• Maclntyre E. A., D'Auriol L., Duparc N., Leveger G., Galibert F., Sigaux F. Use of oligonucleotide probes directed against T-cell antigen receptor gamma delta variable (diversity)-joining junctional sequences as a general method for detecting minimal residual disease in acute lymphoblastic leukemias. J. Clin. Invest. 1990; 86: 2125–2135
   PubMed Web of Science ®Google Scholar
• Shtivelman E., Lifshitz B., Gale R. P., Canaani E. Fused transcript of abl and bcr genes in chronic myelogenous leukemia. Nature 1985; 315: 550–554
   PubMed Web of Science ®Google Scholar
• Fainstein E., Marcelle C., Rosner A., Canaani E., Gale R. P., Dreazen O., Smith S. D., Croce C. M. A new fused transcript in Philadelphia chromosome positive acute lymphocytic leukemia. Nature 1987; 330: 386–388
   PubMed Web of Science ®Google Scholar
• Kawasaki E. S., Clark S. S., Coyne M. Y., Smith S. D., Champlin R., Witte O. N., McCormick F. P. Diagnosis of chronic myeloid and acute lymphocytic leukemias by detection of leukemia-specific mRNA sequences amplified in vitro. Proc. Natl. Acad. Sci. U.S.A. 1988; 85: 5698–5702
   PubMed Web of Science ®Google Scholar
• Kakizuka A., Miller W. H., Jr, Umesono K., Warrell R. P., Jr, Frankel S. R., Murty V. V. V. S., Dmitovsky E., Evans R. M. Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RAR-α with a novel putative transcription factor, PML. Cell 1991; 66: 663–674
   PubMed Web of Science ®Google Scholar
• De ThÉ H., Lavau C., Marcio A., Chomienne C., Degos L., Dejean A. The PML-RAR-α fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR. Cell 1991; 66: 675–684
   PubMed Web of Science ®Google Scholar
• Giguere V., Ong E. S., Segui P., Evans R. M. Identification of a receptor for the morphogen retinoic acid. Nature 1987; 330: 624–629
   PubMed Web of Science ®Google Scholar
• Miller W. H., Jr, Kakizuka A., Frankel S. R., Warrell R. P., Jr, Deblasio A., Levine K., Evans R. M., Dmitovsky E. Reverse transcription polymerase chain reaction for the rearranged retinoic acid receptor α clarifies diagnosis and detects minimal residual disease in acute promyelocytic leukemia. Proc. Natl. Acad. Sci. USA. 1992; 89: 2694–2698
   PubMed Web of Science ®Google Scholar
• Downing J. R., Head D. R., Curcio-Brint A. M., Hulshof M. G., Motroni T. A., Raimondi S. C., Carroll A. J., Drabkin H. A., Willman C., Theil K. S., Civin C. I., Erickson P. An AML1/ETO fusion transcript is consistently detected by RNA-based polymerase chain reaction in acute myelogenous leukemia containing the (8;21)(q22;q22) translocation. Blood 1993; 81: 2860–2865
   PubMed Web of Science ®Google Scholar
• Inoue K., Sugiyama H., Ogawa H., Nakagawa M., Yamagami T., Miwa H., Kita K., Hiraoka A., Masaoka T., Nasu K., Kyo T., Dohy H., Nakauchi H., Ishidate T., Akiyama T., Kishimoto T. WT1 as new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia. Blood 1994; 84: 3071–3079
   PubMed Web of Science ®Google Scholar
• Call K. M., Glaser T., Ito C. Y., Buckler A. J., Pelletier J., Haber D. A., Rose E. A., Kral A., Yeger H., Lewis W. H., Jones C., Housman D. E. Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus. Cell 1990; 60: 509–520
   PubMed Web of Science ®Google Scholar
• Gessler M., Poustka A., Cavenee W., Neve R. L., Orkin S. H., Bruns G. A. P. Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping. Nature 1990; 343: 774–778
   PubMed Web of Science ®Google Scholar
• Coppes M. J., Campbell C. E., Williams B. R. G. The role of WT1 in Wilms tumorigenesis. FASEB J. 1993; 7: 886–895
   PubMed Web of Science ®Google Scholar
• Rauscher F. J., III. The WT1 Wilms tumor gene product: a developmentally regulated transcription factor in the kidney that functions as a tumor suppressor. FASEB J. 1993; 7: 896–903
   PubMed Web of Science ®Google Scholar
• Haber D. A., Park S., Maheswaran S., Englert C., Re G. G., Hazen-Martin D. J., Sens D. A., Garvin A. J. WT1-mediated growth suppression of Wilms tumor cells expressing a WT1 splicing variant. Science 1993; 262: 2057–2059
   PubMed Web of Science ®Google Scholar
• Drummond I. A., Madden S. L., Rohwer-Nutter P., Bell G. I., Sukhatme V. P., Rauscher F. J., III. Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1. Science 1992; 257: 674–678
   PubMed Web of Science ®Google Scholar
• Gashler A. L., Bontbron D. T., Madden S. L., Rauscher F. J., III, Collins T., Sukhatme V. P. Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1. Proc. Natl. Acad. Sci. U.S.A. 1992; 89: 10984–10988
   PubMed Web of Science ®Google Scholar
• Harrington M. A., Konicek B., Song A., Xia X-L., Fredericks W. J., Rauscher F. J., III. Inhibition of colony-stimulating factor-1 promoter activity by the product of the Wilms' tumor locus. J. Biol. Chem. 1993; 268: 21271–21275
   PubMed Web of Science ®Google Scholar
• Werner H., Re G. G., Drummond I. A., Sukhatme V. P., Rauscher F. J., III, Sens D. A., Garvin A. J., Leroith D., Roberts C. T., Jr. Increased expression of the insulin-like growth factor I receptor gene, IGF1R, in Wilms tumor is correlated with modulation of IGF1R promoter activity by the WT1 Wilms tumor gene product. Proc. Natl. Acad. Sci. U.S.A. 1993; 90: 5828–5832
   PubMed Web of Science ®Google Scholar
• Hewitt S. M., Hamada S., McDonnel T. J., Rauscher F. J., III, Saunders G. F. Regulation of the proto-oncogenes bcl-2 and c-myc by the Wilms' tumor suppressor gene WT1. Cancer Res. 1995; 55: 5386–5389
   PubMed Web of Science ®Google Scholar
• Haber D. A., Sohn R. L., Buckler A. J., Pelletier J., Call K. M., Housman D. E. Alternative splicing and genomic structure of the Wilms tumor gene WT1. Proc. Natl. Acad. Sci. U.S.A. 1991; 88: 9618–9622
   PubMed Web of Science ®Google Scholar
• Buckler A. J., Pelletier J., Haber D. A., Glaser T., Housman D. E. Isolation, characterization, and expression of the murine Wilms' tumor gene (WT1) during kidney development. Mol. Cell. Biol. 1991; 11: 1707–1712
   PubMed Web of Science ®Google Scholar
• Park S., Schalling M., Bernard A., Maheswaran S., Shipley G. C., Roberts D., Fletcher J., Shipman R., Rheinwald J., Demetri G., Griffin J., Minden M., Housman D. E., Haber D. A. The Wilms tumor gene WT1 is expressed in murine mesoderm-derived tissues and mutated in a human mesothelioma. Nature Genet. 1993; 4: 415–420
   PubMed Web of Science ®Google Scholar
• Miwa H., Beran M., Saunders G. F. Expression of the Wilms tumor gene (WT1) in human leukemias. Leukemia 1992; 6: 405–409
   PubMed Web of Science ®Google Scholar
• Miyagi T., Ahuja H., Kubota T., Kubonishi I., Koeffler H. P., Miyoshi I. Expression of the Candidate Wilms' tumor gene, WT1, in human leukemia cells. Leukemia 1993; 7: 970–977
   PubMed Web of Science ®Google Scholar
• Menssen H. D., Renkl H-J., Rodeck U., Maurer J., Notter M., Schwartz S., Reinhardt R., Thiel E. Presence of Wilms' tumor gene (wt1) transcripts and the WT1 nuclear protein in the majority of human acute leukemias. Leukemia 1995; 9: 1060–1067
   PubMed Web of Science ®Google Scholar
• Tamaki H., Ogawa H., Inoue K., Soma T., Yamagami T., Miyake S., Oka Y., Oji Y., Tatekawa T., Tsuboi A., Tagawa S., Kitani T., Miwa H., Kita K., Aozasa K., Kishimoto T., Sugiyama H. Increased expression of the Wilms tumor gene (WT1) at relapse in acute leukemia. Blood 1996; 88: 4396–4399
   PubMed Web of Science ®Google Scholar
• Brieger J., Weidmann E., Fenchel K., Mitrou P. S., Hoelzer D., Bergmann L. The expression of the Wilms' tumor gene in acute myelocytic leukemias as a possible marker for leukemic blast cells. Leukemia 1994; 8: 2138–2143
   PubMed Web of Science ®Google Scholar
• Inoue K., Ogawa H., Yamagami T., Soma T., Tani Y., Tatekawa T., Oji Y., Tamaki H., Kyo T., Dohy H., Hiraoka A., Masaoka T., Kishimoto T., Sugiyama H. Long-term follow-up of minimal residual disease in leukemia patients by monitoring WT1 (Wilms tumor gene) expression levels. Blood 1996; 88: 2267–2278
   PubMed Web of Science ®Google Scholar
• Inoue K., Ogawa H., Sonoda Y., Kimura T., Sakabe H., Oka Y., Miyake S., Tamaki H., Oji Y., Yamagami T., Tatekawa T., Soma T., Kishimoto T., Sugiyama H. Aberrant overexpression of the Wilms tumor gene (WT1) in human leukemia. Blood 1997; 89: 1405–1412
   PubMed Web of Science ®Google Scholar
• Yamagami T., Sugiyama H., Inoue K., Ogawa H., Tatekawa T., Hirata M., Kudoh T., Akiyama T., Murakami A., Maekawa T., Kishimoto T. Growth inhibition of human leukemic cells by WT1 (Wilmt tumor gene) anti-sense oligodeoxynucleotides: Implications for the involvement of WT1 in leukemogenesis. Blood 1996; 87: 2878–2884
   PubMed Web of Science ®Google Scholar
• King-Underwood L., Renshaw J., Pritchard-Jones K. Mutations in the wilms' tumor gene WT1 in leukemias. Blood 1996; 87: 2171–2179
   PubMed Web of Science ®Google Scholar