High-Grade Transformation of Low-Grade Non-Hodgkin's Lymphomas: Mechanisms of Tumor Progression

References

• Foucar K., Knowles D. M. B cell chronic lymphocytic and prolymphocytic leukemia. Neoplastic Hematopathology. Williams & Wilkins., Baltimore 1992; 181–1208, 1
   Google Scholar
• Richter M. N. Generalized reticular cell sarcoma of lymph nodes associated with lymphatic leukemia. Am. J. Pathol. 1929; 4: 285–292
   Google Scholar
• Foon K. A., Gale R. P. Clinical transformation of chronic lymphocytic leukemia. Nouv. Rev. Fr Hematol. 1988; 30: 385–388
   PubMedGoogle Scholar
• Robertson L. E., Pugh W., O'Breien S., Kantarjian H., Hir-Sch-Ginsberg C., Cork A., McLaughlin P., Cabanillas F., Keating M. J. Richter's syndrome: a report on 39 patients. J. Clin. Oncol. 1993; 11: 1985–1989
   PubMed Web of Science ®Google Scholar
• Han T., Ohtaki K., Sadamori N., Block A. W., Badbey B., Ozer H., Sandberg A. A. Cytogenetic evidence for clonal evolution in B-cell chronic lymphocytic leukemia. Cancer Genet. Cytogenet. 1986; 23: 321–328
   PubMed Web of Science ®Google Scholar
• Miyamura K., Osada H., Yamauchi T., Itoh M., Kodera Y., Suchi T., Takahashi T., Ueda R. Single clonal origin of neoplastic B-cells with different immunoglobulin light chains in a patient with Richter's syndrome. Cancer 1990; 66: 140–144
   PubMed Web of Science ®Google Scholar
• Sun T., Susin M., Desner M., Pergolizzi R., Cuomo J., Koduru P. The clonal origin of two cell populations in Richter's syndrome. Hum. Parhol. 1990; 21: 722–728
   PubMed Web of Science ®Google Scholar
• Bernard D. J., Bignon Y. J., Pauchard J., Ramos F., Fonck Y., Courjar F., Chollet P., Plagne R. Genotypic analyses of Richter's syndrome. Cancer 1991; 67: 997–1002
   PubMed Web of Science ®Google Scholar
• Schots R., Dehou M. F., Jochmans K., Heirman C., De Waele M., Van Camp B., Thielemans K. Southem blot analysis in a case of Richter's syndrome. Evidence for a postrearrangement heavy chain gene deletion associated with the altered phenotype. Am. J. Clin. Pathol. 1991; 95: 571–577
   PubMed Web of Science ®Google Scholar
• Nakamine H., Masih A. S., Sanger W. G., Wickert R. S., Mitchell D. W., Armitage J. O., Weisenburger D. D. Richter's syndrome with different immunoglobulin light chain types. Molecular and cytogenetic features indicate a common clonal origin. Am. J. Clin. Pathol. 1992; 97: 656–663
   PubMed Web of Science ®Google Scholar
• Cherepakhin V., Baird S. M., Meisenholder G. W., Kipps T. J. Common clonal origin of chronic lymphocytic leukemia and high-grade lymphoma of Richter's syndrome. Blood 1993; 82: 3141–3147
   PubMed Web of Science ®Google Scholar
• Traweek S. T., Liu J., Johnson R. M., Winberg C. D., Rappaport H. High-grade transformation of chronic lymphocytic leukemia and low-grade non-Hodgkin's lymphoma. Genotypic confirmation of clonal identity. Am. J. Clin. Pathol. 1993; 100: 519–526
   PubMed Web of Science ®Google Scholar
• Koduru P. R. K., Lichtman S. M., Similari T. F., Sun T., Goh J. C., Karp L., Hall W., Hashimoto S., Chiorazzi N., Broome J. D. Serial phenotypic, cytogenetic and molecular genetic studies in Richter's syndrome: demonstration of lymphoma development from the chronic lymphocytic leukaemia cells. Br J. Haematol. 1993; 85: 613–616
   PubMed Web of Science ®Google Scholar
• Splitner T. A., Noorloos B. V., Van Heerde P. CLL and diffuse histiocytic lymphoma in one patient: clonal proliferation of two different B cells. Scand. J. Haematol. 1978; 20: 29–36
   PubMedGoogle Scholar
• Van Dongen J. J., Hooijkaas H., Michiels J. J., Grosveld G., De Klein A., Van Der Kwast T. H., Prins M. E., Abels J., Hagemejer A. Richter's syndrome with different immunoglobulin light chains and different heavy chain gene rearrangements. Blood 1984; 64: 571–575
   PubMed Web of Science ®Google Scholar
• McDonnell J. M., Beschorner W. E., Staal S. P., Spivak J. L., Mann R. B. Richter's syndrome with two different B-cell clones. Cancer; 1986; 58: 2031–2037
   PubMed Web of Science ®Google Scholar
• Trümper L., Matthaei-Maurer D. U., Knauf W., MÖLler P. Centroblastic lymphoma of the thyroid supervening long-lasting chronic lymphocytic leukemia (B-CLL) demonstration of biclonality by immunohistochemical and gene rearrangement analysis. Klin. Wochenschr 1988; 66: 736–124
   PubMedGoogle Scholar
• Ostrowski M., Minden M., Wang C., Bailey D. Immunophenotypic and gene probe analysis of a case of Richter's syndrome. Am. J. Clin. Pathol. 1989; 91: 215–221
   PubMed Web of Science ®Google Scholar
• Matolcsy A., Casali P., Knowles D. M. Different clonal origin of B-cell populations of chronic lymphocytic leukemia and large-cell lymphoma in Richter's syndrome. N. Y. Acad. Sci. 1995; 764: 496–503
   PubMed Web of Science ®Google Scholar
• Mederios L. J., Stetler-Stevenson M. Composite B-cell and T-cell lymphoma. Coincidental occurrence or related neoplasms?. Am. J. Clin. Pathol. 1992; 98: 387–389
   PubMed Web of Science ®Google Scholar
• Foon K. A., Thiruvengadam R., Saven A., Bernstein I., And P., Gale R. P. Genetic relatedness of lymphoid malignancies. Transformation of chronic lymphocytic leukemia as a model. Ann. Intern. Med. 1993; 119: 63–73
   PubMed Web of Science ®Google Scholar
• Kim H. Composite lymphoma and related disorders. Am. J. Clin. Pathol. 1992; 99: 445–451
   Web of Science ®Google Scholar
• Matolcsy A., Inghirami G., Knowles D. M. Molecular genetic demonstration of the diverse evolution of Richter's syndrome (chronic lymphocytic leukemia and sub-sequential large cell lymphoma). Blood 1994; 83: 1363–1372
   PubMed Web of Science ®Google Scholar
• Alt F. W., Oltz E. M., Young F., Gorman J., Taccioli G., Chen J. VDJ recombination. Immunol. Today 1992; 13: 306–314
   PubMedGoogle Scholar
• Travis L. B., Curtis R. E., Hankey B. F., Fraumeni J. F. Second cancers in patients with chronic lymphocytic leukemia. J. Natl. Cancer Inst. 1992; 84: 1422–1427
   PubMed Web of Science ®Google Scholar
• Volpe G., Gamberi B., Pastore C., Roetto A., Pautasso M., Parvis G., Camaschella C., Mazza U., Saglio G., Gaidano G. Analysis of microsatallite instability in chronic lymphoproliferative disorders. Ann. Hemutol. 1996; 72: 67–71
   PubMed Web of Science ®Google Scholar
• Brynes R. K., McCourty A., Sun N. C. J., Koo C. H. Trisomy 12 in Richter's transformation of chronic lymphocytic leukemia. Am. J. Clin. Pathol. 1995; 104: 199–203
   Web of Science ®Google Scholar
• Torelli U. L., Torelli G. M., Emilia G., Selleri L., Ven-Turelli D., Artusi T., Donelli A., Colo A., Fomieri C. Simultaneously increased expression of the c-myc and p chain genes in the acute blastic transformation of chronic lymphocytic leukaemia. Br J. HaematoL 1987; 65: 165–170
   PubMed Web of Science ®Google Scholar
• Ginsberg A. M., Raffeld M., Cossman J. Inacti-vation of the retinoblasoma gene in human lymphoid neoplasms. Blood 1991; 77: 833–840
   PubMed Web of Science ®Google Scholar
• Gaidano G., Ballerini P., Gong J. Z., Inghirami G., Neri A., Newcomb E. W., Magrath I. T., Knowles D. M., Dalla-Favera R. p53 mutations in human lymphoid malignances: association with Burkitt lymphoma and chronic lymphocytic leukemia. Proc. Natl. Acad. Sci. USA 1991; 88: 5413–5417
   PubMed Web of Science ®Google Scholar
• Ichikawa A., Hotta T., Takagi N., Tsushita K., Kinoshita T., Nagai H., Murakami Y., Hayashi K., Saito H. Mutation of p53 gene and their relations to disease progression in B-cell lymphoma. Blood 1992; 79: 2701–2707
   PubMed Web of Science ®Google Scholar
• Golay J., Luppi M., Songia S., Palvarini C., Lombardi L., Aiello A., Delia D., Lam K., Crawford D. H., Biondi A., Barbui T., Rambaldi A., Introna M. Expression of A-myb, but not c-myb and B-myb, is restricted to Burkitt's lymphoma, sIg+ B-acute lymphoblastic leukemia, and a subset of chronic lymphocytic leukemias. Blood 1996; 87: 1900–1911
   PubMed Web of Science ®Google Scholar
• Pinyol M., Cobo F., Bea S., Jares P., Nayach I., Fernandez P. L., Montserrat E., Cardesa A., Campo E. p16INK4a gene inactivation by deletions, mutations, and hyper-mathylation is associated with transformed and aggressive variants of non-Hodgkin's lymphomas. Blood 1998; 91: 2977–2984
   PubMed Web of Science ®Google Scholar
• Han T., Sadamori N., Ozer H., Gajera R., Gomez G. A., Henderson E. S., Bhargava A., Fitzpatrick J., Minowada J., Bloom M. L. Cytogenetic studies in 77 patients with chronic lymphocytic leukemia: correlations with clinical, immunologic, and phenotypic data. J. Clin. Oncol. 1984; 2: 1121–1134
   PubMed Web of Science ®Google Scholar
• Heben J., Jonveaux P., D'Agay M. F., Berger R. Cytogenetic studies in patients with Richter's syndrome. Cancer Genet. Cytogenet. 1994; 73: 65–68
   PubMed Web of Science ®Google Scholar
• Oscier D., Fitchett M., Herbert T., Lambert R. Karyotypic evolution in B-cell chronic lymphocytic leukaemia. Genes Chromosomes Cancer 1991; 3: 16–20
   PubMed Web of Science ®Google Scholar
• Matolcsy A., Chadburn A., Knowles D. M. De novo CD5-positive and Richter's syndrome-associated diffuse large B cell lymphomas are genotypically distinct. Am. J. Pathol. 1995; 147: 207–216
   PubMed Web of Science ®Google Scholar
• Ersbøll J., Schultz H. B., Perdersen-Bjergaard J., Nis-Sen N. J. Follicular low grade non-Hodglun's lymphoma: long-term outcome with or without tumor progression. Eur. J. Haematol. 1989; 42: 155–163
   PubMed Web of Science ®Google Scholar
• Harris N. L., Jaffe E. S., Stein H., Banks P. M., Chan J. K. C., Cleary M. L., Delsol G., Wolf-Peeters C. D., Falini B., Gatter K. C., Grogan T. M., Isaacson P. G., Knowles D. M., Mason D. Y., Muller-Hermelink H. K., Pileri S. A., Pins M. A., Ralfkiaer E., Warnke R. A. A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. Blood 1994; 84: 1361–1392
   PubMed Web of Science ®Google Scholar
• Cullen M. H., Lister T. A., Brearley R. L., Shand W. S., Stansfeld A. G. Histological transformation of non-Hodgkin's lymphoma. A prospective study. Cancer 1979; 44: 645–651
   PubMed Web of Science ®Google Scholar
• Garvin A. J., Simon R. M., Osbome C. K., Memll J., Young R. C., Berard. C. W. An autopsy study of histologic progression in non-Hodgkin's lymphomas. 192 cases from the National Cancer Institute. Cancer; 1983; 52: 393–398
   PubMed Web of Science ®Google Scholar
• Hubbard S. M., Chabner B. A., Devita V. J., Simon R., Berard C. W., Jones R. B., Garvin A. J., Canellos G. P., Osbome C. K., Young R. C. Histologic progression in non-Hodgkin's lymphoma. Blood 1982; 59: 258–264
   PubMed Web of Science ®Google Scholar
• Siegelman M. H., Cleary M. L., Wamke R., Sklar J. Frequent biclonality and Ig gene alterations among B cell lymphomas that show multiple histologic forms. J. Exp. Med. 1985; 161: 850–863
   PubMed Web of Science ®Google Scholar
• Zelenetz A. D., Chen T. T., Levy R. Histologic transformation of follicular lymphoma to diffuse lymphoma represents tumor progression by a single malignant B cell. J. Exp. Med. 1991; 173: 197–207
   PubMed Web of Science ®Google Scholar
• Matolcsy A., Casali P., Warnke R. A., Knowles D. M. Morphologic transformation of follicular lymphoma is associated with somatic mutation of the translocated bcl-2 gene. Blood 1996; 88: 3937–3944
   PubMed Web of Science ®Google Scholar
• Price C. G. A., Tuszynski A., Watt S. M., Murdoch S. J., Lister T. A., Young B. D. Detection of additional JH/BCL2 translocations in follicular lymphoma. Leukemia 1991; 5: 548–557
   PubMed Web of Science ®Google Scholar
• Yunis J. J., Frizzera G., Oken M. M., McKenna J., Theologides A., Amesen M. Multiple recurrent gre-nomic defects in follicular lymphoma. A possible model for cancer. N. Engl. J. Med., 316: 79–84
   PubMed Web of Science ®Google Scholar
• Richardson M. E., Quanguang C., Filippa D. A., Offit K., Hampton A., Koduru P. R. K., Jhanwar S. C., Lieberman P. H., Clarkson B. D., Chaganti R. S. K. Intermediate-to high-grade histology of lymphomas carrying t(14;18) is associated with additional nonrandom chromosome changes. Blood 1987; 70: 444–447
   PubMed Web of Science ®Google Scholar
• Armitage J. O., Sanger W. G., Weisenburger D. D., Harrington D. S., Linder J., Bierman P. J., Vose J. M., Purtilo D. T. Correlation of secondary cytogenetic abnormalities with histologic appearance in non-Hodgkin's lymphomas bearing t(14;18)(q32;q21). J. Natl. Cancer, Inst. 1988; 80: 576–580
   PubMed Web of Science ®Google Scholar
• Whang-Peng J., Knutsen T., Jaffe E. S., Steinberg S. M., Raffeld M., Zhao W. P., Duffey P., Condron K., Yano T., Longo D. L. Sequential analysis of 43 patients with non-Hodgkin's lymphoma: clinical correlations with cytogenetic, histologic, immunophenotyping, and molecular studies. Blood 1995; 85: 203–216
   PubMed Web of Science ®Google Scholar
• Johansson B., Mertens E, Mitelman F. Cytogenetic evolution patterns in non-Hodgkin's lymphoma. Blood 1995; 86: 3905–3914
   PubMed Web of Science ®Google Scholar
• Bernell P., Jacobsson B., Liliemark J., Hjalmar V., Arvids-Son I., Hast R. Gain of chromosome 7 marks the progression from indolent to aggressive follicle centre lymphoma and is a common finding in patients with diffuse large B-cell lymphoma: a study by FISH. Br. J. Haemarol. 1998; 101: 487–491
   PubMed Web of Science ®Google Scholar
• Bentz M., Wemer C. A., DÖHner H., Joos S., Barth T. F., Siebert R., Schroder M., Stilgenbauer S., Fischer K., MÖLler P., Lichter P. High incidence of chromosomal imbalances and gene amplifications in the classical follicular variant of follicle center lymphoma. Blood 1996; 88: 1437–1444
   PubMed Web of Science ®Google Scholar
• Raghoebier S., Broos L., Kramer M. H. H., Van Krieken J. H. J. M., Kluin-Nelemans J. C., Van Ommen, And Kluin G. J. B., Ph. M. Histological conversion of follicular lymphoma with structural alterations of t(14;18) and immunoglobulin genes. Leukemia 1995; 9: 1748–1755
   PubMed Web of Science ®Google Scholar
• Reed J. C., Tanaka S. Somatic point mutations in the translocated bcl-2 genes of non-Hodgkin's lymphomas and lymphocytic leukemias: implications for mechanisms of tumor progression. Leukemia Lymphoma 1993; 10: 157–163
   PubMed Web of Science ®Google Scholar
• Yang E., Korsmeyer S. J. Molecular thanatopsis: a discourse on the BCL2 family and cell death. Blood 1996; 88: 386–401
   PubMed Web of Science ®Google Scholar
• De Jong D., Voetdijk B. M., Beverstock G. C., Van Ornmer G. J. B., Willemze R., Kluin P. M. Activation of the c-myc oncogene in a precursor-B-cell blast crisis of follicular lymphoma presenting as a composite Iymphoma. N. Engl. J. Med. 1988; 318: 1373–1378
   PubMed Web of Science ®Google Scholar
• Gauwerky C. E., Haluska F. G., Tsujimoto Y., Nowell P. C., Croce C. M. Evolution of B-cell malignancy: pre-B-cell leukemia resulting from MYC activation in a B-cell neoplasm with a rearranged BCL2 gene. Proc. Natl. Acad. Sci. USA 1988; 85: 8548–8552
   PubMed Web of Science ®Google Scholar
• Lee J. T., Innes D. J., Williams M. E. Sequential bcl-2 and c-myc oncogene rearrangements associated with the clinical transformation of non-Hodglun's lymphoma. J. Clin. Invest. 1989; 84: 1454–1459
   PubMed Web of Science ®Google Scholar
• Fiedler W., Weh H. J., Zeller W., Fonatsch C., Hillion J., Larsen C., WÖRmann B., Hossfeld D. K. Trans-location (14;18) and (8;22) in three patients with acute leuke-mia/lymphoma following centrocytic/centroblastic non-Hodgkin's lymphoma. Ann. Hematol. 1991; 63: 282–287
   PubMed Web of Science ®Google Scholar
• Yano T., Jaffe E. S., Longo D. L., Raffeld M. MYC rearrangements in histologically progressed follicular lymphomas. Blood 1992; 80: 758–767
   PubMed Web of Science ®Google Scholar
• Strasser A., Harris A. W., Bath M. L., Cory S. Novel primitive lymphoid tumors induced in transgenic mice by cooperation between myc and bcl-2. Nature 1990; 348: 331–333
   PubMed Web of Science ®Google Scholar
• Martin M. C., Hsu B., Stephens L. C., Brisbay S., McDonnell T. J. The functional basis of c-myc and bcl-2 complementation during multistep lymphomagenesis in vivro. Exp. Cell. Res. 1995; 217: 240–247
   PubMed Web of Science ®Google Scholar
• Lo Coco F., Gaidano G., Louie D. C., Offit K., Chaganti R. S. K., Dalla-Favera R. p53 mutations are associated with histologic transformation of follicular lymphoma. Blood 1993; 82: 2289–2295
   PubMed Web of Science ®Google Scholar
• Sander C. A., Yano T., Clark H. M., Harris C., Longo D. L., Jaffe E. S., Raffeld M. p53 mutation is associated with progression in follicular lymphomas. Blood 1993; 82: 1994–2004
   PubMed Web of Science ®Google Scholar
• Symmans W. F., Katz R. L., Ordonez N. G., Dalton H., Romaguera J. E., Cabanillas F. Transformation of follicular lymphoma. Expression of p53 and bcl-2 oncoprotein, apoptosis and cell proliferation. Acta Cytol 1995; 39: 673–682
   PubMed Web of Science ®Google Scholar
• Elenitoba-Johnson K. S. J., Gascoyne R. D., Lim M. S., Chhanabai M., Jaffe E. S., Raffeld M. Homoxy-gous deletions at chromosome 9p21 involving p16 and p15 are associated with histologic progression in follicle center lymphoma. Blood 1998; 91: 4677–4685
   PubMed Web of Science ®Google Scholar
• Villuendas R., SÁNchez-Beato M., Martinez J. C., Saez A. I., Martinez-Delgado B., Garcia J. F., Mateo M. S., Sanchez-Verde L., Benitez J., Martinez P., Pins M. A. Loss of p16/INK4A protein expression in non-Hodgkin's lymphomas is a frequent finding associated with tumor progression. Am. J. Pathol. 1998; 153: 887–897
   PubMed Web of Science ®Google Scholar
• Banks P. M., Chan J., Cleary M. L., Clew M. L., Delsol G., De Wolf-Peeters C., Gatter K., Grogan T. M., Harris N. L., Isaacson P. G., Jaffe E. S., Mason D., Pileri S., Ralskiaer E., Stein H., Warnke R. A. Mantle cell lymphoma. A proposal for unification of morphologic, immunologic, and molecular data. Am. J. Surg. Pathol. 1992; 16: 637–640
   PubMed Web of Science ®Google Scholar
• Williams M. E., Westermann C. D., Swerdlow S. H. Genotypic characterization of centrocytic lymphoma: frequent rearrangement of the chromosome 11 bcl-1 locos. Blood 1990; 76: 1387–1391
   PubMed Web of Science ®Google Scholar
• Ott G., Kalla J., Ott M., Schryen B., Katzenberger T., Muller J. G., Muller-Hermelink H. K. Blastoid variants of mantle cell lymphoma: frequent bcl-1 rearrangements at the major translocation cluster region and tetraploid chromosome clones. Blood 1997; 89: 1421–1429
   PubMed Web of Science ®Google Scholar
• Kaleem Z., Wakoff A. R., Smith R. P., Hess J. L. Blastic transformation of mantle cell lymphoma. Arch. Pathol. Lab. Med. 1996; 120: 577–580
   PubMed Web of Science ®Google Scholar
• Norton A. J., Matthews J., Pappa V., Shamash J., Love S., Rohatiner A. Z., Lister T. A. Mantle cell lymphoma: natural history defined in a serially biopsied population over 20-year period. Ann. Oncol. 1995; 6: 249–256
   PubMed Web of Science ®Google Scholar
• Lardelli P., Bookman M. A., Sundeen J., Longo D. L., Jaffe E. S. Lymphocytic lymphoma of intermediate differentiation. Morphologic and immunophenotypic spectrum and clinical correlations. Am. J. Surg. Pathol. 1990; 14: 752–763
   PubMed Web of Science ®Google Scholar
• Hernandez L., Fest T., Cazorla M., Teruya-Feldstein C., Bosch F., Peinado M. A., Pins M. A., Montserratm E., Cardesa A., Jaffe E. S., Campo E., Raffeld M. p53 gene mutations and protein overexpression are associated with aggressive variants of mantle cell lymphomas. Blood 1996; 87: 3351–3359
   PubMed Web of Science ®Google Scholar
• Issacson P. G. Lymphomas of mucosa-associated lymphoid tissue (MALT). Histopathol. 1990; 16: 617–619
   PubMed Web of Science ®Google Scholar
• Chan J. K. C., Ng C. S., Isaacson P. G. Relationship between high-grade lymphoma and low grade B-cell mucosa-associated lymphoid tissue lymphoma (MALToma) of the stomach. Am. J. Pathol. 1990; 136: 1153–1164
   Web of Science ®Google Scholar
• Montalbin C., Manzanal A., Castrillo J. M., Escribano L., Bellas C. Low grade gastric B-cell MALT lymphoma progressing into high grade lymphoma. Clonal identity of the two stages of the tumor, unusual bone involvment and leukaemic dissemination. Histopathol. 1995; 27: 89–91
   PubMed Web of Science ®Google Scholar
• Matolcsy A., Nagy M., Kisfaludy N., KelÉNyi G. Distinct clonal origin of low-grade MALT-type and high-grade lesions of a multifocal gastric lymphoma. Histopathol. 1998, in print)
   Web of Science ®Google Scholar
• Peng H., Diss T., Isaacson P. G., Pan L. c-myc gene abnormalities in mucosa-associated lymphoid tissue (MALT) lymphomas. J. Pathol. 1997; 181: 381–386
   PubMed Web of Science ®Google Scholar
• Du M., Peng H., Singh N., Isaacson P. G., Pan L. The accumulation of p53 abnormalities is associated with progression of mucosa-associated lymphoid tissue lymphoma. Blood 1995; 86: 4587–4593
   PubMed Web of Science ®Google Scholar
• Omonishi K., Yoshino T., Sakuma I., Kobayashi K., Moriyama M., Akagi T. bcl-6 protein is identified in high-grade but not low-grade mucosa-associated lymphoid tissue lymphomas of the stomach. Mod. Pathol. 1998; 11: 181–185
   PubMed Web of Science ®Google Scholar
• Peng H., Chen G., Du M., Singh N., Isaacson P. G., Pan L. Replication emor phenotype and p53 gene mutation in lymphomas of mucosa-associated lymphoid tiussue. Am. J. Pathol. 1996; 148: 643–648
   PubMed Web of Science ®Google Scholar
• Rosin M. P., Anwar W. A., Ward A. J. Inflamation, chromosomal instability, and cancer: the schistosomiasis model. Cancer Res. 1994; 54: 1929–1933
   PubMed Web of Science ®Google Scholar
• Enno A., O'Rourke J., Braye S., Howlett R., Lee A. Antigen-dependent progression of mucosa-associated lymphoid tissue (MALT)-type lymphoma in the stomach. Am. J. Pathol. 1998; 152: 1625–1632
   PubMed Web of Science ®Google Scholar
• Schroeder H. W., Dighiero G. The pathogenesis of chronic lymphocytic leukemia: analysis of the antibody repertoire. Immunol. Today 1994; 15: 288–294
   PubMedGoogle Scholar
• Houldsworth J., Chaganti R. S. K. Comparative genomic hybridization: an overview. Am. J. Pathol. 1994; 145: 1253–1260
   PubMed Web of Science ®Google Scholar
• Lisitsyn N., Lisitsyn N., Wigler M. Clonong the differences between two complex genomes. Science 1993; 259: 946–950
   PubMed Web of Science ®Google Scholar