Differentiation of Leukemic Cells Induced by Short-Course High-Dose Methylprednisolone in Children with Different Subtypes of Acute Myeloblastic Leukemia

References

• Paran M., Sachs L., Barak Y., Resnitzky P. In vitro induction of granulocyte differentiation in hematopoie‐tic cells from leukemic and nonleukemic patients. Proc. Natl. Acad. Sci. USA 1970; 67: 1542–1549
   PubMed Web of Science ®Google Scholar
• Sachs L. Control of normal cell differentiation and phenotypic reversion of malignancy in myeloid leukemia. Nature 1978; 274: 535–539
   PubMed Web of Science ®Google Scholar
• Breitman T. R., Selonic S. E., Collins S. J. Induction of differentiation of the human promyelocytic leukemia cell line ( HL‐60) by retinoic acid. Proc. Natl. Acad. Sci. 1980; 77: 2936–2940
   PubMed Web of Science ®Google Scholar
• Sachs L. Differentiation of myeloid leukemia cells : new possibilities for therapy. Br. J. Haematol. 1978; 40: 509–517
   PubMed Web of Science ®Google Scholar
• Huang M. E., Ye Y. C., Chen S. R., Chai J. R., Lu J. X., Zhao L., Gu L. J., Wang Z. Y. Use of all‐trans retinoic acid in the treatment of acute promyelocytic leukemia. Blood 1988; 72: 567–572
   PubMed Web of Science ®Google Scholar
• Degos L., Dombret H., Chomienne C., Daniel M., Miclea J., Chastang C., Castaigne S., Fenaux P. All‐trans‐retinoic acid as a differentiating agent in the treatment of acute promyelocytic leukemia. Blood 1995; 85: 2643–2653
   PubMed Web of Science ®Google Scholar
• Koeffler H. P. Induction of differentiation of the human acute myelogenous leukemia cells; therapeutic implications. Blood 1983; 62: 709–721
   PubMed Web of Science ®Google Scholar
• Hozumi M. Fundamentals of myeloid leukemia by induction of leukemia cell differentiation. Adv. Cancer Res. 1983; 38: 121–169
   PubMed Web of Science ®Google Scholar
• Lotem J., Sachs L. Induction of specific changes in the surface membrane of myeloid leukemic cells by steroid hormones. Int. J. Cancer 1975; 15: 731–740
   PubMed Web of Science ®Google Scholar
• Honma Y., Kasukabe T., Okabe J., Hozumi M. Glucocorticoid induced differentiation of cultured mouse myeloid leukemic cells. Gann 1977; 68: 241–246
   PubMedGoogle Scholar
• Honma Y., Kasukabe T., Okabe J., Hozumi M. Prolongation of survival time of mice inoculated with myeloid leukemia cells by inducers of normal differentiation. Cancer Res. 1979; 39: 3167–3171
   PubMed Web of Science ®Google Scholar
• Kasukabe T., Honma Y., Hozumi M., Suda T., Nishii Y. Control of proliferating potential of myeloid leukemia cells during long term treatment with vitamin D3 analoques and other differentiation inducers in combination with anti‐leukemic drugs. In vitro and in vivo studies. Cancer Res. 1987; 47: 567–572
   PubMed Web of Science ®Google Scholar
• Honma Y., Kasukabe T., Okabe J., Hozumi M. Glucocorticoid binding and mechanism of resistance in some clones of mouse myeloid leukemic cells resistant to induction of differentiation by dexamethasone. J. Cell Physiol. 1977; 93: 227–236
   PubMed Web of Science ®Google Scholar
• Hiçsönmez G., Özsoylu S., Tuncer A. M. Differentiation of myeloid leukemic cells induced by high‐dose methylprednisolone in patients with acute myeloblastic leukemia and its therapeutic potential. Leuk. Res. 1991; 15: 537–541
   PubMed Web of Science ®Google Scholar
• Hiçsöanmez G., Özsoylu Ş., Gürgey A., Zamani V. P., Irken G. High‐dose methylprednisolone for remission induction in children with acute nonlymphoblastic leukemia. Eur J. Haematol. 1989; 42: 498–500
   PubMed Web of Science ®Google Scholar
• Hiponmez G., Tuncer A. M., Güler E., Tan E., Teke‐lioElu M. The potential role of high‐doae methylprednisolone on the maturation of leukemic cells in children with acute promyelocytic leukemia (APL). Exp. Hematol. 1993; 21: 599–601
   PubMed Web of Science ®Google Scholar
• Hiçsönmez G., Özsoylu Ş., Tuncer A. M., Ertürk G., Özbek N., Karadeniz N. Direct niorphologic evidence of high‐dose methylprednisolone induced maturation of leukemic cells in children with acute nonlymphoblastic leukemia. Exp. Hematol. 1991; 19: 232–233
   PubMed Web of Science ®Google Scholar
• Bennett J. M., Catovsky D., Daniel M. T., Flandrin G., Gal‐ton D. A., Gralnick H. R., Sultan C. Proposals for the clasification of the acute leukeiniaa : French‐ American‐British (FAB) co‐operative group. Br J. Haematol. 1976; 33: 451–458
   PubMed Web of Science ®Google Scholar
• Kawada H., Ichikawa Y., Watanabe S., Nagao T., Ari‐mori S. Flow cytometric analysis of cell‐surface antigen expressions on acute myeloid leukemia cell populations according to their cell‐size. Leuk. Res. 1994; 18: 29–35
   PubMed Web of Science ®Google Scholar
• Hiçsönmez G., Özsoylu Ş., Onat N., Zainani V. P., Gümrük F., Tuncer M. High‐dose inelhylprednisolone in resistant and relapsed children with acute lymphoblastic leukemia. Med. Pediatr Oncol. 1994; 22: 68–69
   PubMedGoogle Scholar
• Hiçsönmez G., Gümrük F., Zainani V. P., Tuncer A. M., Yetgin S., Gürgey A., Özsoylu Ş. High‐dose methylprednisolone for children with acute lymphoblastic leukemia and unfavorable presenting features. Eur. J. Haematol. 1997; 58: 26–31
   PubMed Web of Science ®Google Scholar
• Granville N. B., Rubio E., Unugur A., Schulman E., Dameshek W. Treatment of acute leukemia in adults with massive doses of prednisone and prednisolone. N. Engl. J. Med. 1958; 259: 207–213
   PubMed Web of Science ®Google Scholar
• Shanbrom E., Miller S. Critical evaluation of massive steroid therapy ot acute leukemia. N Engl. J Med 1962; 266: 1354–1358
   PubMed Web of Science ®Google Scholar
• Hiçsönmez G., Tuncer A. M., Cetin M., Cümrük F., Kara A., Yalçin S. Morphologic evidence of in vivo differentiation in acute myeloblastic leukemia. Acta. Haematol. 1993; 90: 214–215
   PubMed Web of Science ®Google Scholar
• Hiçsönmez G., Gümrük F. Giant dysplastic neutrophils Possible morphologic evidence of in viva differentiation of leukemic cells in acute myeloblastic leukemia. Am. J. Hematol. 1995; 49: 168–170
   PubMed Web of Science ®Google Scholar
• Castaigne S., Chomienne C., Daniel M. T., Berger R., Fenaux P., Degos L. All trans‐retinoic acid as a differentiating therapy for acute promyelocytic leukemias, I Clinical results. Blood 1990; 76: 1704–1709
   PubMed Web of Science ®Google Scholar
• Sachs L., Lotem J. Control of programmed cell death in normal and leukemic cells: New implications for therapy. Blood 1993; 82: 15–21
   PubMed Web of Science ®Google Scholar
• Martin S. J., Bradley J. G., Cotter T. G. HL‐60 cells induced to differentiate towards neutrophils suhsequently die via apoptosis. Clin. Exp. Immunol. 1990; 79: 448–453
   PubMed Web of Science ®Google Scholar
• Hiçsönmez G., Erdemli E., TekelioElu M., Tuncer A. M., Ozbek N., Çetin M., Cotter M T.G. Morphologic evidence of apoptosis in childhood acute myeloblastic leukemia treated with high‐dose methylprednisolone. Leuk Lymph. 1996; 22: 91–96
   PubMed Web of Science ®Google Scholar
• Hiçsönmez G., Çetin M., Tunç B., Tuncer A. M., Günirük F., Yenicesu I. Dramatic resolution of pleural effusion in children with chronic myelomonocytic leukemia following short‐course high‐dose methylprednisolone. Leuk Lymph. 1998; 29: 617–623
   PubMed Web of Science ®Google Scholar
• Miyoshi H., Ohki M., Nakagawa T., Honma Y. Glucocorticoids induce apoptosis in acute myeloid leukemia cell lines with a t(8;21) chromosome translocation. Leuk. Res. 1997; 21: 45–50
   PubMed Web of Science ®Google Scholar
• Hiçsönmez G., Karadeniz N., Zamani V. P., Tuncer A. M., Gümrük F., Ertürk G., Gürgey A., Özsoylu Ş. High remission rate in acute myeloblastic leukemia in chiidren treated with high‐dose methylprednisolonc. Eur. J. Hatmatol. 1992; 48: 215–220
   PubMed Web of Science ®Google Scholar
• Hiçsönmez G., Tuncer A. M., Şayli T., Güler E., Çetin M., Mufti G. J. High‐dose methylprednisolone, low‐dose cytosine arabinoside and mitoxantrone in children with myelodysplastic syndromes. Hematol. Pathol. 1995; 9: 185–193
   PubMedGoogle Scholar
• Kita K., Nakase K., Miwa H., Masuya M., Nishii K., Morita N., Takakura N., Otuji A., Shirakawa S., Ueda T., Nasu K., Kyo T., Dohy H., Kamada N. Pheno‐typical charasteristics of acute niyelocytic leukemia associated with the t( 8, 21) (q22;q22) chromosomal abnormality : Frequent expression of immature B‐cell antigen CD19 together with stem cell antigen CD34. Blood 1992; 80: 470–477
   PubMed Web of Science ®Google Scholar
• Hiçsönmez G., Onat N., Albayrak D., Yetgin S., Özsoylu Ş. Acceleration of leukocyte recovery by administration of short‐course high‐dose methylprednisolone in children with acute lymphoblastic leukemia. Pediatr. Hematol/Oncol. 1991; 8: 193–197
   PubMed Web of Science ®Google Scholar
• Çetin M., Hiçsönmez G., Tuncer A. M., Kansu E., Can‐pinar H. The effect of short‐course high‐dose corti‐costeroid therapy on peripheral blood CD34 positive progenitor cells in children with acute leukemia. Exp. Hematol. 1996; 24: 963–966
   Google Scholar
• Tuncer A. M., Hiçsönmez G., Gümrük F., Şayli T., Güler E., Çetin M., Okur H. Serum TNF‐alfa, gamma‐INF, G‐CSF and GM‐CSF level in neutropenic children with acute leukemia treated with short‐ course high‐dose methylprednisolone. Leuk. Res. 1996; 20: 265–269
   PubMed Web of Science ®Google Scholar