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Research Article

Pharmacokinetics and pharmacodynamics of chlorambucil delivered in long-circulating nanoemulsion

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Pages 125-133 | Received 14 Jun 2009, Accepted 05 Aug 2009, Published online: 12 Jan 2010

References

  • Benita S, Levy MY. (1993). Submicron emulsions as colloidal drug carriers for intravenous administration: comprehensive physicochemical characterization. J Pharm Sci, 82(11): 1069–1079.
  • Collins-Gold LC, Lyons RT, Bartholow LC. (1990). Parenteral emulsions for drug delivery. Adv Drug Deliv Rev, 5(3): 189–208.
  • Desai A, Vyas T, Amiji M. (2008). Cytotoxicity and apoptosis enhancement in brain tumor cells upon coadministration of paclitaxel and ceramide in nanoemulsion formulations. J Pharm Sci, 97(7): 2745–2756.
  • Dorr R, Fritz W. (1982). Cancer Chemotherapy Handbook. New York: Elsevier Science.
  • Driscoll DF. (2006). Lipid injectable emulsions: 2006. Nutr Clin Pract, 21(4): 381–386.
  • Francis GE, Delgado C, Fisher D, Malik F, Agrawal AK. (1996). Polyethylene glycol modification: relevance of improved methodology to tumour targeting. J Drug Target, 3(5): 321–340.
  • Gabizon A, Goren D, Horowitz AT, Tzemach D, Lossos A, Siegal T. (1997). Long-circulating liposomes for drug delivery in cancer therapy: a review of biodistribution studies in tumor-bearing animals. Adv Drug Deliv Rev, 24(2-3): 337–344.
  • Galton D, Israels L, Nabarro J, Till M. (1965). Clinical trials of p.di (2-chloroethylamine)-phenylbutyric acid (CB1348) in malignant lymphoma. BMJ, II: 1172.
  • Ganta S, Amiji M. (2009). Coadministration of paclitaxel and curcumin in nanoemulsion formulations to overcome multidrug resistance in tumor cells. Mol Pharm, 6(3): 928–939.
  • Ganta S, Devalapally H, Baguley BC, Garg S, Amiji M. (2008a). Microfluidic preparation of chlorambucil nanoemulsion formulations and evaluation of cytotoxicity and pro-apoptotic activity in tumor cells. J Biomed Nanotechnol, 4: 165–173.
  • Ganta S, Paxton JW, Baguley BC, Garg S. (2008b). Pharmacokinetics and pharmacodynamics of chlorambucil delivered in parenteral emulsion. Int J Pharm, 360(1-2): 115–121.
  • Hall AG, Tilby MJ. (1992). Mechanisms of action of, and modes of resistance to, alkylating agents used in the treatment of haematological malignancies. Blood Rev, 6(3): 163–173.
  • Handa T, Saito H, Miyajima K. (1990). Phospholipid monolayers at the triolein-saline interface: production of microemulsion particles and conversion of monolayers to bilayers. Biochemistry, 29(11): 2884–2890.
  • Hultin M, Carneheim C, Rosenqvist K, Olivecrona T. (1995). Intravenous lipid emulsions: removal mechanisms as compared to chylomicrons. J Lipid Res, 36: 2174–2184.
  • Igarashi R, Takenaga M, Matsuda T. (1996). Distribution of lipid microsphere preparations. Adv Drug Deliv Rev, 20(2-3): 147–154.
  • Jain RK. (1994). Barriers to drug delivery in solid tumors. Sci Am, 271(1): 58–65.
  • Khandavilli S, Panchagnula R. (2007). Nanoemulsions as versatile formulations for paclitaxel delivery: peroral and dermal delivery studies in rats. J Invest Dermatol, 127: 154–162.
  • Lundberg BB, Mortimer BC, Redgrave TG. (1996). Submicron lipid emulsions containing amphipathic polyethylene glycol for use as drug-carriers with prolonged circulation time. Int J Pharm, 134(1-2): 119–127.
  • Lundberg BB, Griffiths G, Hansen HJ. (1999). Conjugation of an anti-B-cell lymphoma monoclonal antibody, LL2, to long-circulating drug-carrier lipid emulsions. J Pharm Pharmacol, 51: 1099–1105.
  • Maeda H, Matsumura Y. (1989). Tumoritropic and lymphotropic principles of macromolecular drugs. Crit Rev Ther Drug Carrier Syst, 6: 193–210.
  • Maeda H, Wu J, Sawa T, Matsumura Y, Hori K. (2000). Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J Control Release, 65(1–2): 271–284.
  • Mizushima Y, Hoshi K. (1993). Recent advances in lipid microspheres technology for targeting prostaglandin delivery. J Drug Target, 1: 93–100.
  • Moghimi SM, Hunter AC, Murray JC. (2001). Long-circulating and target-specific nanoparticles: theory to practice. Pharmacol Rev, 53(2): 283–318.
  • Oku N, Namba Y. (1994). Long-circulating liposomes. Crit Rev Ther Drug Carrier Syst, 11: 231–270.
  • Ozono S, Miyao N, Igarashi T, Marumo K, Nakazawa H, Fukuda M, Tsushima T, Tokuda N, Kawamura J, Murai M. (2004). Tumor doubling time of renal cell carcinoma measured by CT: collaboration of Japanese Society of Renal Cancer. Jpn J Clin Oncol, 34(2): 82–85.
  • Patlolla RR, Vobalaboina V. (2005a). Pharmacokinetics and tissue distribution of etoposide delivered in long circulating parenteral emulsion. J Drug Target, 13(10): 543–553.
  • Patlolla RR, Vobalaboina V. (2005b). Pharmacokinetics and tissue distribution of etoposide delivered in parenteral emulsion. J Pharm Sci, 94(2): 437–445.
  • Rossi J, Giasson S, Khalid MN, Delmas P, Allen C, Leroux J-C. (2007). Long-circulating poly(ethylene glycol)-coated emulsions to target solid tumors. Eur J Pharm Biopharm, 67(2): 329–338.
  • Sarker DK. (2005). Engineering of nanoemulsions for drug delivery. Curr Drug Deliv, 2: 297–310.
  • Seki J, Sonoke S, Saheki A, Fukui H, Sasaki H, Mayumi T. (2004). A nanometer lipid emulsion, lipid nano-sphere (LNS), as a parenteral drug carrier for passive drug targeting. Int J Pharm, 273(1–2): 75–83.
  • Shimada K, Miyagishima A, Sadzuka Y, Nozawa Y, Mochizuki Y, Ohshima H, Hirota S. (1995). Determination of the thickness of the fixed aqueous layer around polyethyleneglycol-coated liposomes. J Drug Target, 3(4): 283–289.
  • Storm G, Belliot SO, Daemen T, Lasic DD. (1995). Surface modification of nanoparticles to oppose uptake by the mononuclear phagocyte system. Adv Drug Deliv Rev, 17(1): 31–48.

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