The alpha-fetoprotein third domain receptor binding fragment: in search of scavenger and associated receptor targets

References

• Mizejewski GJ. Alpha-fetoprotein structure and function: relevance to isoforms, epitopes, and conformational variants. Exp Biol Med 2001;226:377–408
   PubMed Web of Science ®Google Scholar
• Luft AJ, Lorscheider FL. Structural analysis of human and bovine alpha-fetoprotein by electron microscopy, image processing, and circular dichroism. Biochemistry 1983;22:5978–81
   PubMed Web of Science ®Google Scholar
• Mizejewski G. Mapping of structure-function peptide sites on the human alpha-fetoprotein amino acid sequence. Atlas Genet Cytogenet Oncol Haematol 2009:1–65 . Available at: http://AtlasGeneticsOncology.org/Deep/MappingAFPID20077.html
   Google Scholar
• Naidu S, Peterson ML, Spear BT. Alpha-fetoprotein related gene (ARG): a new member of the albumin gene family that is no longer functional in primates. Gene 2010;449:95–102
   PubMed Web of Science ®Google Scholar
• Mizejewski GJ. Physiology of alpha-fetoprotein as a biomarker for perinatal distress: relevance to adverse pregnancy outcome. Exp Biol Med 2007;232:993–1004
   PubMed Web of Science ®Google Scholar
• Mizejewski GJ. Mechanism of cancer growth suppression of alpha-fetoprotein derived growth inhibitory peptides (GIP): comparison of GIP-34 versus GIP-8 (AFPep). Updates and prospects. Cancers 2011;3:2709–33
   PubMedGoogle Scholar
• Mizejewski GJ. Biological role of alpha-fetoprotein in cancer: prospects for anticancer therapy. Expert Rev Anticancer Ther 2002;2:709–35
   PubMedGoogle Scholar
• Mizejewski GJ, MacColl R. Alpha-fetoprotein growth inhibitory peptides: potential leads for cancer therapeutics. Mol Cancer Ther 2003;2:1243–55
   PubMed Web of Science ®Google Scholar
• Mizejewski GJ, Mirowski M, Garnuszek P, et al. Targeted delivery of anti-cancer growth inhibitory peptides derived from human alpha-fetoprotein: review of an International Multi-Center Collaborative Study. J Drug Target 2010;18:575–88
   PubMed Web of Science ®Google Scholar
• Mizejewski GJ. Review of the putative cell-surface receptors for alpha-fetoprotein: identification of a candidate receptor protein family. Tumour Biol 2011;32:241–58
   PubMed Web of Science ®Google Scholar
• Mizejewski GJ. Review of the adenocarcinoma cell surface receptor for human alpha-fetoprotein; proposed identification of a widespread mucin as the tumor cell receptor. Tumour Biol 2013;34:1317–36
   PubMed Web of Science ®Google Scholar
• Atemezem A, Mbemba E, Marfaing R, et al. Human alpha-fetoprotein binds to primary macrophages. Biochem Biophys Res Commun 2002;296:507–14
   PubMed Web of Science ®Google Scholar
• Yamamoto M, Tatsumi T, Miyagi T, et al. Alpha-fetoprotein impairs activation of natural killer cells by inhibiting the function of dendritic cells. Clin. Exp Immunol 2011;165:211–19
   PubMed Web of Science ®Google Scholar
• Li M, Li H, Li C, et al. Cytoplasmic alpha-fetoprotein functions as a co-repressor in RA-RAR signaling to promote the growth of human hepatoma Bel 7402 cells. Cancer Lett 2009;285:190–9
   PubMed Web of Science ®Google Scholar
• Posypanova GA, Gorokhovets NV, Makarov VA, et al. Recombinant alpha-fetoprotein C-terminal fragment: the new recombinant vector for targeted delivery. J Drug Target 2008;16:321–8
   PubMed Web of Science ®Google Scholar
• Yabbarov NG, Posypanova GA, Vorontsov EA, et al. A new system for targeted delivery of doxorubicin into tumor cells. J Control Release 2013;168:135–41
   PubMed Web of Science ®Google Scholar
• Godovannyi AV, Vorontsov EA, Gukasova NV, et al. Targeted delivery of paclitaxel-loaded recombinant alpha-fetoprotein fragment-conjugated nanoparticles to tumor cells. Dokl Biochem Biophys 2011;439:158–60
   PubMed Web of Science ®Google Scholar
• Sharapova OA, Iurkova MS, Andronova SM, et al. High-efficient renaturation of immobilized recombinant C-terminal fragment of human alpha-fetoprotein. Prikl Biokhim Mikrobiol 2011;47:523–9
   PubMedGoogle Scholar
• Sharapova OA, Pozdnykova NV, Laurinavichyute DK, et al. High-efficient expression, refolding and purification of functional recombinant C-terminal fragment of human alpha-fetoprotein. Protein Expr Purif 2010;73:31–5
   PubMed Web of Science ®Google Scholar
• Sharapova OA, Pozdniakova NV, Laurinavichiute DK, et al. Purification and characterization of recombinant human alpha-fetoprotein fragment, corresponding to the C-terminal structural domain. Bioorg Khim 2010;36:760–8
   PubMedGoogle Scholar
• Festin SM, Bennett JA, Fletcher PW, et al. The recombinant third domain of human alpha-fetoprotein retains the antiestrotrophic activity found in the full-length molecule. Biochim Biophys Acta 1999;1427:307–14
   PubMed Web of Science ®Google Scholar
• Posypanova GA, Makarov VA, Savvateeva MV, et al. The receptor binding fragment of alpha-fetoprotein is a promising new vector for the selective delivery of antineoplastic agents. J Drug Target 2013;21:458–65
   PubMed Web of Science ®Google Scholar
• Carter DC, He XM, Munson SH, et al. Three-dimensional structure of human serum albumin. Science 1989;244:1195–8
   PubMed Web of Science ®Google Scholar
• Mizejewski G. Alpha-fetoprotein as a biomarker in immunodeficiency diseases: relevance to ATAXIA telangiectasia and related disorders. J Immunodefic Disor 2014;3:1–12
   Google Scholar
• Osmond RI, Das S, Crouch MF. Development of cell-based assays for cytokine receptor signaling, using an AlphaScreen SureFire assay format. Anal Biochem 2010;403:94–101
   PubMed Web of Science ®Google Scholar
• Palm NW, Medzhitov R. Pattern recognition receptors and control of adaptive immunity. Immunol Rev 2009;227:221–33
   PubMed Web of Science ®Google Scholar
• Mori T, Takahashi K, Naito M, et al. Endocytic pathway of scavenger receptors via trans-Golgi system in bovine alveolar macrophages. Lab Investig 1994;71:409–16
   PubMed Web of Science ®Google Scholar
• Sahoo D, Drover V. The role of scavenger receptors in signaling, inflammation, and atherosclerosis. In: Cheema SK, ed. Biochemistry of atherosclerosis. New York: Springer; 2006:53–69
   Google Scholar
• Huang Y, Zhu XY, Du MR, Li DJ. Human trophoblasts recruited T lymphocytes and monocytes into decidua by secretion of chemokine CXCL16 and interaction with CXCR6 in the first-trimester pregnancy. J Immunol 2008;180:2367–75
   PubMed Web of Science ®Google Scholar
• Matsumura T, Sakai M, Kobori S, et al. Two intracellular signaling pathways for activation of protein kinase C are involved in oxidized low-density lipoprotein-induced macrophage growth. Arterioscler Thromb Vasc Biol 1997;17:3013–20
   PubMed Web of Science ®Google Scholar
• Greaves DR, Gordon S. Thematic review series: the immune system and atherogenesis. Recent insights into the biology of macrophage scavenger receptors. J Lipid Res 2005;46:11–20
   PubMed Web of Science ®Google Scholar
• Tran-Thanh D, Done SJ. The role of stromal factors in breast tumorigenicity. Am J Pathol 2010;176:1072–4
   PubMed Web of Science ®Google Scholar
• Satoh H, Kiyota E, Terasaki Y, et al. Expression and localization of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in murine and human placentas. J Histochem Cytochem 2008;56:773–84
   PubMed Web of Science ®Google Scholar
• Silverstein RL, Baird M, Lo SK, Yesner LM. Sense and antisense cDNA transfection of CD36 (glycoprotein IV) in melanoma cells. Role of CD36 as a thrombospondin receptor. J Biol Chem 1992;267:16607–12
   PubMed Web of Science ®Google Scholar
• Czokalo M, Tomasiak M. Alpha fetoprotein inhibits aggregation of human platelets. Haematologia 1989;22:11–18
   PubMedGoogle Scholar
• Politz O, Gratchev A, McCourt PA, et al. Stabilin-1 and -2 constitute a novel family of fasciclin-like hyaluronan receptor homologues. Biochem J 2002;362:155–64
   PubMed Web of Science ®Google Scholar
• Irjala H, Elima K, Johansson EL, et al. The same endothelial receptor controls lymphocyte traffic both in vascular and lymphatic vessels. Eur J Immunol 2003;33:815–24
   PubMed Web of Science ®Google Scholar
• Ishii J, Adachi H, Aoki J, et al. SREC-II, a new member of the scavenger receptor type F family, trans-interacts with SREC-I through its extracellular domain. J Biol Chem 2002;277:39696–702
   PubMed Web of Science ®Google Scholar
• Beauvillain C, Meloni F, Sirard JC, et al. The scavenger receptors SRA-1 and SREC-I cooperate with TLR2 in the recognition of the hepatitis C virus non-structural protein 3 by dendritic cells. J Hepatol 2010;52:644–51
   PubMed Web of Science ®Google Scholar
• Paidassi H, Tacnet-Delorme P, Verneret M, et al. Investigations on the C1q-calreticulin-phosphatidylserine interactions yield new insights into apoptotic cell recognition. J Mol Biol 2011;408:277–90
   PubMed Web of Science ®Google Scholar
• Ramirez-Ortiz ZG, Pendergraft WF 3rd, Prasad A, et al. The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity. Nat Immunol 2013;14:917–26
   PubMed Web of Science ®Google Scholar
• Leito JT, Ligtenberg AJ, Nazmi K, et al. A common binding motif for various bacteria of the bacteria-binding peptide SRCRP2 of DMBT1/gp-340/salivary agglutinin. Biol Chem 2008;389:1193–200
   PubMed Web of Science ®Google Scholar
• Bikker FJ, Ligtenberg AJ, End C, et al. Bacteria binding by DMBT1/SAG/gp-340 is confined to the VEVLXXXXW motif in its scavenger receptor cysteine-rich domains. J Biol Chem 2004;279:47699–703
   PubMed Web of Science ®Google Scholar
• Koba H, Okuda K, Watanabe H, et al. Role of lysine in interaction between surface protein peptides of Streptococcus gordonii and agglutinin peptide. Oral Microbiol Immunol 2009;24:162–9
   PubMedGoogle Scholar
• Goncalves CM, Castro MA, Henriques T, et al. Molecular cloning and analysis of SSc5D, a new member of the scavenger receptor cysteine-rich superfamily. Mol Immunol 2009;46:2585–96
   PubMed Web of Science ®Google Scholar
• Miro-Julia C, Escoda-Ferran C, Carrasco E, et al. Expression of the innate defense receptor S5D-SRCRB in the urogenital tract. Tissue Antigens 2014;83:273–85
   PubMed Web of Science ®Google Scholar
• Juarez-Meavepena M, Carreon-Torres E, Lopez-Osorio C, et al. The Srb1+1050T allele is associated with metabolic syndrome in children but not with cholesteryl ester plasma concentrations of high-density lipoprotein subclasses. Metab Syndrome Relat Disord 2012;10:110–16
   PubMed Web of Science ®Google Scholar
• Canfran-Duque A, Ramirez CM, Goedeke L, et al. microRNAs and HDL life cycle. Cardiovasc Res 2014;103:414–22
   PubMed Web of Science ®Google Scholar
• Lavie M, Sarrazin S, Montserret R, et al. Identification of conserved residues in hepatitis C virus envelope glycoprotein E2 that modulate virus dependence on CD81 and SRB1 entry factors. J Virol 2014;88:10584–97
   PubMed Web of Science ®Google Scholar
• Bari MF, Weickert MO, Sivakumar K, et al. Elevated soluble CD163 in gestational diabetes mellitus: secretion from human placenta and adipose tissue. PLoS One 2014;9:e101327
   PubMed Web of Science ®Google Scholar
• Stilund M, Reuschlein AK, Christensen T, et al. Soluble CD163 as a marker of macrophage activity in newly diagnosed patients with multiple sclerosis. PloS One 2014;9:e98588
   PubMed Web of Science ®Google Scholar
• Zizkovsky V, Havranova M, Strop P, Korcakova J. A spectroscopic study of the hemin-human-alpha-fetoprotein system. Ann N Y Acad Sci 1983;417:57–60
   PubMed Web of Science ®Google Scholar
• Bartha JL, Comino-Delgado R, Arce F, et al. Relationship between alpha-fetoprotein and fetal erythropoiesis. J Reprod Med 1999;44:689–97
   PubMed Web of Science ®Google Scholar
• Hu J, Liu J, Yang D, et al. Physiological roles of asialoglycoprotein receptors (ASGPRs) variants and recent advances in hepatic-targeted delivery of therapeutic molecules via ASGPRs. Protein Peptide Lett 2014;21:1025–30
   PubMed Web of Science ®Google Scholar
• Yang SH, Heo D, Lee E, et al. Galactosylated manganese ferrite nanoparticles for targeted MR imaging of asialoglycoprotein receptor. Nanotechnology 2013;24:475103
   PubMed Web of Science ®Google Scholar
• Vincent PE, Sherwin SJ, Weinberg PD. The effect of the endothelial glycocalyx layer on concentration polarisation of low density lipoprotein in arteries. J Theor Biol 2010;265:1–17
   PubMed Web of Science ®Google Scholar
• Echavarria-Heras H, Leal-Ramirez C, Castillo O. Surface aggregation patterns of LDL receptors near coated pits III: potential effects of combined retrograde membrane flow-diffusion and a polarized-insertion mechanism. Theor Biol Med Model 2014;11:23
   PubMed Web of Science ®Google Scholar
• Zhang Y, Zhou L, Kong-Beltran M, et al. Calcium-independent inhibition of PCSK9 by affinity-improved variants of the LDL receptor EGF(A) domain. J Mol Biol 2012;422:685–96
   PubMed Web of Science ®Google Scholar
• Strom TB, Tveten K, Laerdahl JK, Leren TP. Mutation G805R in the transmembrane domain of the LDL receptor gene causes familial hypercholesterolemia by inducing ectodomain cleavage of the LDL receptor in the endoplasmic reticulum. FEBS Open Bio 2014;4:321–7
   PubMed Web of Science ®Google Scholar
• Martinez-Pomares L. The mannose receptor. J Leukocyte Biol 2012;92:1177–86
   PubMed Web of Science ®Google Scholar
• Raiber EA, Tulone C, Zhang Y, et al. Targeted delivery of antigen processing inhibitors to antigen presenting cells via mannose receptors. ACS Chem Biol 2010;5:461–76
   PubMed Web of Science ®Google Scholar
• Tjomsland V, Ellegard R, Kjolhede P, et al. Blocking of integrins inhibits HIV-1 infection of human cervical mucosa immune cells with free and complement-opsonized virions. Eur J Immunol 2013;43:2361–72
   PubMed Web of Science ®Google Scholar
• Holik AK, Rohm B, Somoza MM, Somoza V. N(epsilon)-Carboxymethyllysine (CML), a Maillard reaction product, stimulates serotonin release and activates the receptor for advanced glycation end products (RAGE) in SH-SY5Y cells. Food Funct 2013;4:1111–20
   PubMed Web of Science ®Google Scholar
• Charoonpatrapong K, Shah R, Robling AG, et al. HMGB1 expression and release by bone cells. J Cell Physiol 2006;207:480–90
   PubMed Web of Science ®Google Scholar
• Nimpf J, Schneider WJ. From cholesterol transport to signal transduction: low density lipoprotein receptor, very low density lipoprotein receptor, and apolipoprotein E receptor-2. Biochim Biophys Acta 2000;1529:287–98
   PubMed Web of Science ®Google Scholar
• Reddy SS, Connor TE, Weeber EJ, Rebeck W. Similarities and differences in structure, expression, and functions of VLDLR and ApoER2. Mol Neurodegener 2011;6:30
   PubMed Web of Science ®Google Scholar
• Mizejewski GJ. Alpha-fetoprotein as a biologic response modifier: relevance to domain and subdomain structure. Proc Soc Exp Biol Med 1997;215:333–62
   PubMed Web of Science ®Google Scholar
• Terentiev AA, Moldogazieva NT. Cell adhesion proteins and alpha-fetoprotein. Similar structural motifs as prerequisites for common functions. Biochem Biokhim 2007;72:920–35
   PubMed Web of Science ®Google Scholar
• Muehlemann M, Miller KD, Dauphinee M, Mizejewski GJ. Review of growth inhibitory peptide as a biotherapeutic agent for tumor growth, adhesion, and metastasis. Cancer Metastasis Rev 2005;24:441–67
   PubMed Web of Science ®Google Scholar
• Mizejewski GJ, Butterstein G. Survey of functional activities of alpha-fetoprotein derived growth inhibitory peptides: review and prospects. Curr Protein Pept Sci 2006;7:73–100
   PubMed Web of Science ®Google Scholar
• Mizejewski GJ. Therapeutic use of human alpha-fetoprotein in clinical patients: is a cancer risk involved? Int J Cancer 2011;128:239–42
   PubMed Web of Science ®Google Scholar
• Vakharia D, Mizejewski GJ. Human alpha-fetoprotein peptides bind estrogen receptor and estradiol, and suppress breast cancer. Breast Cancer Res Treat 2000;63:41–52
   PubMed Web of Science ®Google Scholar
• Lemmon MA, Schlessinger J, Ferguson KM. The EGFR family: not so prototypical receptor tyrosine kinases. Cold Spring Harbor Perspect Biol 2014;6:a020768
   PubMed Web of Science ®Google Scholar
• Pak V. The use of alpha-fetoprotein for the delivery of cytotoxic payloads to cancer cells. Ther Deliv 2014;5:885–92
   PubMedGoogle Scholar
• Yabbarov NG, Posypanova GA, Vorontsov EA, et al. Targeted delivery of doxorubicin: drug delivery system based on PAMAM dendrimers. Biochem Biokhim 2013;78:884–94
   PubMed Web of Science ®Google Scholar
• Pozdniakova NV, Gorokhovets NV, Gukasova NV, et al. New protein vector ApE1 for targeted delivery of anticancer drugs. J Biomed Biotechnol 2012;2012:469756
   PubMed Web of Science ®Google Scholar
• Lee YJ, Lee SW. Regression of hepatocarcinoma cells using RNA aptamer specific to alpha-fetoprotein. Biochem Biophys Res Commun 2012;417:521–7
   PubMed Web of Science ®Google Scholar
• Tatarinova ON, Gorokhovets NV, Makarov VA, et al. New protein vectors based on an alpha-fetoprotein fragment for targeted DNA delivery into cancer cells. Vestn Ross Akad Med Nauk 2010:3–8
   Google Scholar
• Severin ES, Posypanova GA. Molecular physiology of receptor mediated endocytosis and its role in overcoming multidrug resistance. Ross Fiziol Zh IM Sechenova 2011;97:553–65
   PubMedGoogle Scholar
• Pardee AD, Mizejewski GJ, Butterfield LH. Route of delivery dictates the immunostimulatory activity of DC-based vaccines for hepatocellular carcinoma (Abstract). University of Pittsburgh Annual Department of Immunology Retreat, November 25, 2014
   Google Scholar
• Bei R, Mizejewski GJ. Alpha fetoprotein is more than a hepatocellular cancer biomarker: from spontaneous immune response in cancer patients to the development of an AFP-based cancer vaccine. Curr Mol Med 2011;11:564–81
   PubMed Web of Science ®Google Scholar
• He Y, Hong Y, Mizejewski GJ. Engineering alpha-fetoprotein-based gene vaccines to prevent and treat hepatocellular carcinoma: review and future prospects. Immunotherapy 2014;6:725–36
   PubMed Web of Science ®Google Scholar
• Dauphinee MJ, Mizejewski GJ. Human alpha-fetoprotein contains potential heterodimerization motifs capable of interaction with nuclear receptors and transcription/growth factors. Med Hypotheses 2002;58:453–61
   PubMed Web of Science ®Google Scholar
• Mizejewski GJ. An apparent dimerization motif in the third domain of alpha-fetoprotein: molecular mimicry of the steroid/thyroid nuclear receptor superfamily. Bioessays 1993;15:427–32
   PubMed Web of Science ®Google Scholar