328
Views
10
CrossRef citations to date
0
Altmetric
Original Article

Inhibitory effect of epirubicin-loaded lipid microbubbles with conjugated anti-ABCG2 antibody combined with therapeutic ultrasound on multiple myeloma cancer stem cells

, , , , , , , , & show all
Pages 34-46 | Received 26 Mar 2015, Accepted 13 May 2015, Published online: 23 Jul 2015

References

  • Borrello I. Can we change the disease biology of multiple myeloma? Leuk Res 2012;36:S3–S12
  • Bladé J, Cibeira MT, Fernández de Larrea C, et al. Multiple myeloma. Ann Oncol 2010;21: vii313–19
  • Saini N, Mahindra A. Therapeutic strategies for the treatment of multiple myeloma. Discov Med 2013;15:251–8
  • Chou T. Multiple myeloma: recent progress in diagnosis and treatment. J Clin Exp Hematopathol 2012;52:149–59
  • Paíno T, Ocio EM, Paiva B, et al. CD20 positive cells are undetectable in the majority of multiple myeloma cell lines and are not associated with a cancer stem cell phenotype. Haematologica 2012;97:1110–14
  • Agarwal JR, Matsui W. Multiple myeloma: a paradigm for translation of the cancer stem cell hypothesis. Anti-Cancer Agents Med Chem 2010;10:116–20
  • Ghosh N, Matsui W. Cancer stem cells in multiple myeloma. Cancer Lett 2009;277:1–7
  • Fratino L, Rupolo M, Mazzuccato M, et al. Autologous stem cell transplantation and multiple myeloma cancer stem cells. Anticancer Agents Med Chem 2013;13:1419–29
  • Matsui W, Huff CA, Wang Q, et al. Characterization of clonogenic multiple myeloma cells. Blood 2004;103:2332–6
  • Hajek R, Okubote SA, Svachova H. Myeloma stem cell concepts, heterogeneity and plasticity of multiple myeloma. Br J Haematol 2013;163:551–64
  • Villa R, Cerroni B, Viganò L, et al. Targeted doxorubicin delivery by chitosan-galactosylated modified polymer microbubbles to hepatocarcinoma cells. Colloids Surf B Biointerfaces 2013;110:434–42
  • Geers B, De Wever O, Demeester J, et al. Targeted liposome-loaded microbubbles for cell-specific ultrasound-triggered drug delivery. Small 2013;9:4027–35
  • Ren ST, Liao YR, Kang XN, et al. The antitumor effect of a new docetaxel-loaded microbubble combined with low-frequency ultrasound in vitro: preparation and parameter analysis. Pharm Res 2013;30:1574–85
  • Sorace AG, Warram JM, Umphrey H, et al. Microbubble-mediated ultrasonic techniques for improved chemotherapeutic delivery in cancer. J Drug Target 2012;20:43–54
  • Azmin M, Harfield C, Ahmad Z, et al. How do microbubbles and ultrasound interact? Basic physical, dynamic and engineering principles. Curr Pharm Des 2012;18:2118–34
  • Wang Y, Bai WK, Shen E, et al. Sonoporation by low-frequency and low-power ultrasound enhances chemotherapeutic efficacy in prostate cancer cells in vitro. Oncol Lett 2013;6:495–8
  • Liu H, Chang S, Sun J, et al. Ultrasound-mediated destruction of LHRHa-targeted and paclitaxel-loaded lipid microbubbles induces proliferation inhibition and apoptosis in ovarian cancer cells. Mol Pharm 2014;11:40–8
  • Abe M, Harada T, Matsumoto T. Concise review: defining and targeting myeloma stem cell-like cells. Stem Cells 2014;32:1067–73
  • Lu CT, Zhao YZ, Wu Y, et al. Experiment on enhancing antitumor effect of intravenousepirubicin hydrochloride by acoustic cavitation in situ combined with phospholipid-based microbubbles. Cancer Chemother Pharmacol 2011;68:343–8
  • Tinkov S, Coester C, Serba S, et al. New doxorubicin-loaded phospholipid microbubbles for targeted tumor therapy: in vivo characterization. J Control Release 2010;148:368–72
  • Tinkov S, Winter G, Coester C, Bekeredjian R. New doxorubicin-loaded phospholipid microbubbles for targeted tumor therapy: Part I – formulation development and in vitro characterization. J Control Release 2010;143:143–50
  • Yang F, Zhang M, He W, et al. Controlled release of Fe3O4 nanoparticles in encapsulated microbubbles to tumor cells via sonoporation and associated cellular bioeffects. Small 2011;7:902–10
  • Wang C, Yang F, Xu Z, et al. Intravenous release of NO from lipidic microbubbles accelerates deep vein thrombosis resolution in a rat model. Thromb Res 2013;131:e31–8
  • Yang F, Gu N, Chen D, et al. Experimental study on cell self-sealing during sonoporation. J Control Release 2008;131:205–10
  • Wang L, Li L, Guo Y, et al. Construction and in vitro/in vivo targeting of PSMA-targeted nanoscale microbubbles in prostate cancer. Prostate 2013;73:1147–58
  • Niu C, Wang Z, Lu G, et al. Doxorubicin loaded superparamagnetic PLGA-iron oxide multifunctional microbubbles for dual-mode US/MR imaging and therapy of metastasis in lymph nodes. Biomaterials 2013;34:2307–17
  • Yang CP, Xiong F, Wang J, et al. Anti-ABCG2 monoclonal antibody in combination with paclitaxel nanoparticles against cancer stem-like cell activity in multiple myeloma. Nanomedicine 2014;9:45–60
  • Yang CP, Wang J, Chen D, et al. Paclitaxel-Fe3O4 nanoparticles inhibits the growth of CD138−CD34− tumor stem-like cells in multiple myeloma bearing mice. Int J Nanomed 2013;8:1439–49
  • Dou J, Pan M, Wen P, et al. Isolation and identification of cancer stem like cells from murine melanoma cell lines. Cell Mol Immunol 2007;4:467–72
  • Chen DY, Wang J, Zhang Y, et al. Effect of downregulated transcriptional repressor ZEB1 on the epithelial-mesenchymal transition of ovarian cancer cells. Int J Gynecol Cancer 2013;23:1357–66
  • Lo YL, Ho CT, Tsai FL. Inhibit multidrug resistance and induce apoptosis by using glycocholic acid and epirubicin. Eur J Pharm Sci 2008;35:52–67
  • Lo Y-L. A potential daidzein derivative enhances cytotoxicity of epirubicin on human colon adenocarcinoma Caco-2 cells. Int J Mol Sci 2013;14:158–76
  • Chen JS, Wang J, Zhang Y, et al. Analysis of ovarian cancer stem cell behavior and drug resistance in a three dimensional cell culture. J Biosci Bioeng 2014;118:214–22
  • Zhang Y, Hu H, Song L, et al. Epirubicin-mediated expression of miR-302b is involved in osteosarcoma apoptosis and cell cycle regulation. Toxicol Lett 2013;222:1–9
  • Sun WL, Chen J, Wang YP, et al. Autophagy protects breast cancer cells from epirubicin-induced apoptosis and facilitates epirubicin-resistance development. Autophagy 2011;7:1035–44
  • Villa CH, Dao T, Ahearn I, et al. Single walled carbon nanotubes deliver peptideantigen into dendritic cells and enhance IgG responses to tumor-associated antigens. ACS Nano 2011;5:5300–11
  • Cirstea D, Hideshima T, Rodig S, et al. Dual inhibition of akt/mammaliantarget of rapamycin pathway by nanoparticle albumin-bound–rapamycin and perifosine induces antitumor activity in multiple myeloma. Mol Cancer Ther 2010;9:963–75
  • Hu W, Wang J, Dou J, et al. Augmenting therapy of ovarian cancer efficacy by secreting IL-21 human umbilical cordblood stem cells in nude mice. Cell Transplant 2011;20:669–80
  • Yang CP, He XF, Chen JS, et al. Fe3O4 nanoparticle loaded paclitaxel induce multiple myeloma apoptosis by cell cycle arrest and increase cleavage of caspases in vitro. J Nanopart Res 2013;15:1840
  • Twomey C, McCarthy JV. Pathways of apoptosis and importance in development. J Cell Mol Med 2005;9:345–59
  • Li P, Nijhawan D, Budihardjo I, et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997;91:479–89

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.