Altered Renal α₂-Adrenoceptor Density in Dahl Rats Prenatally Exposed to a High Salt Diet

References

• Edwards E., McCaughran J. A, Jr., Friedman R., Schechter N. Cholinergic receptor site binding, choline acetyltransferase, and acetylcholinesterase activity in the forebrain and brainstem of the Dahl rat model of essential hypertension. Clin Exp Hyper-Theory and Prac. 1983; A5: 1683–1702
   Google Scholar
• Iwai J., Dahl L. K., Knudsen K. D. Genetic influence on the renin-angiotension system. Low renin activities in the hypertensive prone rats. Cir Res. 1973; 32: 678–684
   PubMed Web of Science ®Google Scholar
• Takeshita A., Mark A. L. Neurogenic contribution to hindquarters vasoconstriction during high sodium intake in the Dahl strain of genetically hypertensive rat. Cir Res. 1978; 43(suppl I)86–91
   Google Scholar
• Tobian L., Lange J., Azar S., Iwai J., Koop D., Coffee K., Johnson M. A. Reduction of natriuretic capacity and renin-release in isolated blood perfused kidneys of Dahl hypertension-prone rats. Cir Res. 1978; 43(suppl I)92–98
   PubMed Web of Science ®Google Scholar
• McCaughran J. A., Jr, Edwards E., Friedman R., Schechter N. Myocardial cholinergic receptor sites and enzyme activity in the Dahl model of essential hypertension. Clin Exp Hyper-Theory and Prac. 1984; A6: 811–826
   Google Scholar
• Saavedra J. M., McCarty R., Fernandez-Pardal J., Guicheney P., Weise V., Iwai J. Role of the peripheral sympathetic system in the Dahl salt-sensitive rats. Abstracts from 4th International Symposium on Rats with Spontaneous Hypertension, Heidelberg, 1981; 28
   Google Scholar
• McCaughran J. A., Jr., Juno C. J., Friedman R., Zylan K., O'Malley E. Pre- and neonatal exposure to a high salt diet and the susceptibility to hypertension in the Dahl rat. Clin Exp Hyper-Hyper Pregn 1986, Submitted
   Google Scholar
• Fink G. D., Takeshita A., Mark A. L., Brody M. J. Determinants of renal vascular resistance in the Dahl strain of genetically hypertensive rat. Hypertens. 1980; 2: 274–280
   PubMed Web of Science ®Google Scholar
• Toblan L., Johnson-Hanion S., Zltar M., Iwai J. Total nephrectomy alters circulating humoral agents in salt-fed, low-renln Dahl S rats to favour reduced vasoconstriction in an isolated, perfused bioassay hindquarters. Clin Sci. 1982; 635: 227–230
   Google Scholar
• Takeshita A., Mark A. L., Brody M. J. Prevention of salt-induced hypertension in the Dahl strain by 6-hydroxydopamine. Amer J Physiol. 1979; 236: H48–H52
   PubMed Web of Science ®Google Scholar
• Friedman R., Tassinari L. J., Heine M., Iwai J. Differential development of salt-induced and renal hypertension in Dahl hypertension-sensitive rats after neonatal sympathectomy. Clin Exper Hyper. 1979; 1: 779–799
   PubMed Web of Science ®Google Scholar
• Dibona G. F., Sawin L. L. Renal nerve activity in conscious rats during volume expansion and depletion. Am J Physiol. 1985; 248: F15–F23
   PubMed Web of Science ®Google Scholar
• Dibona G. F. Neurogenic regulation of renal tubular sodium reabsorption. Am J Physiol. 1977; 233: 73–81
   PubMed Web of Science ®Google Scholar
• Starke K. Adrenoceptor subclassification. Rev Physiol Biochem Pharmacol. 1981; 88: 199–236
   PubMedGoogle Scholar
• Starke K. Regulation of noradrenaline release by presynaptic receptor systems. Rev Physiol Biochem Pharmacol. 1977; 77: 1–124
   PubMed Web of Science ®Google Scholar
• Pettinger W. A., Gandler T., Sanchez A., Saavedra J. M. Dietary sodium and renal -adrenergic receptors in Dahl hypertensive rats. Clin Exper Hyper. 1982; A4: 819–828
   Google Scholar
• Pettinger W. A., Sanshez A., Saavedra J., Haywood J. R., Gandler T., Rodes T. Altered renal alpha 2-adrenergic receptor regulation in genetically hypertensive rats. Hypertens. 1982; 4(suppl II)188–192
   PubMedGoogle Scholar
• Fukuda K., Kuchii M., Hano T., Mohara O., Miyamoto Y., Nishio I., Masuyama Y. Changes in renal a–adrenoceptor in experimental hypertension in rats. Jpn Cir J. 1983; 47(10)1221–1226
   PubMedGoogle Scholar
• Summers R. J. Renal a adrenoceptors. Fed Proc. 1984; 43: 2917–2922
   PubMedGoogle Scholar
• Perry B. D., U'Prichard D. C. [3H]Rauwolsclne (α-yohimbine). A specific antagonist radioligand for brain a.-adrenergic receptors. Eur J Pharmacol. 1981; 76: 461–464
   PubMedGoogle Scholar
• Tanaka T., Ashida T., Deguchi F., Ikeda M. 3H-clonidine and3H rauwolsclne binding to membranes from rat cerebral cortex and kidney. Jpn J Pharmacol. 1983; 33: 713–716
   PubMedGoogle Scholar
• Rapp J. P., Dene H. Development and characteristics of Inbred strains of Dahl salt-sensitive (S/JR) and salt-resistant (R/JR) rats. Hypertens. 1985; 7: 340–349
   PubMed Web of Science ®Google Scholar
• McCaughran J. A. Jr., Edwards E., Friedman R., Schechter N. Alpha 1- and alpha 2-adrenoceptor binding in the Dahl rat model of hypertension. Brain Res Bull. 1984; 12: 697–702
   PubMed Web of Science ®Google Scholar
• Lowry D., Rosenbrough N., Farr A., Randall R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951; 193: 265–275
   PubMed Web of Science ®Google Scholar
• Scatchard G. The attractions of proteins for small molecules and ions. Ann of the NY Acad of Sci. 1949; 51: 660–672
   Web of Science ®Google Scholar
• Cheng T., Prusoff W. H. Relationship between the inhibition constant (Ki) and the concentration of the inhibitor that causes 50 percent inhibition (150) of an enzymatic reaction. Biochem Pharmacol. 1973; 22: 3099–3103
   PubMed Web of Science ®Google Scholar
• Rapp J. P. Dahl salt-susceptible and salt-resistant rats. Hypertens. 1983; 4: 753–763
   Google Scholar
• Friedman R., McCann M., Leder R., Iwai J. Genetic predisposition to hypertension and stress-induced alterations in heart rate. Behav Neural Biol. 1982; 35: 426–431
   PubMedGoogle Scholar
• Snavely M. D., Insel P. A. Characterization of alpha-adrenergic receptor subtypes in the rat renal cortex. Differential regulation of alpha - and alpha -adrenergic receptors by guanyl nucleotides and Na. Mol Pharmacol. 1982; 22: 532–546
   PubMedGoogle Scholar
• Pettinger W. A., Keeton T. K., Campbell W. B., Harper D. C. Evidence for a renal a-adrenergic receptor inhibiting renin release. Cir Res. 1976; 38(5)338–346
   PubMedGoogle Scholar
• McPherson G. A., Summers R. J. [3H]Prazosin and [3H]clonidine binding to aadrenoceptors in membranes prepared from regions of rat kidney. J Pharm Pharmacol. 1981; 33: 189–191
   PubMed Web of Science ®Google Scholar
• Young W. S., III, Kuhar M. J. α2-adrenergic receptors are associated with renal proximal tubules. Eur J Pharmacol. 1980; 67: 493–495
   PubMed Web of Science ®Google Scholar
• McPherson G. A., Summers R. J. Evidence from binding studies for α2adrenoceptors directly associated with glomeruli from rat kidney. Eur J Pharmacol. 1983; 90: 333–341
   PubMed Web of Science ®Google Scholar
• Roman R. J., Cowley A. W., Jr, Lechene C. Water diuretic and natriuretic effect of clonidine in the rat. J Pharmacol Exp Ther. 1979; 211: 385–393
   PubMedGoogle Scholar
• McCaughran J. A., Jr., Juno C. J., Friedman R. Pre- and neonatal exposure of the Dahl rat to NaCI: Development and regional distribution of myocardial a.-adrenergic and cholinergic receptor sites. J Autonom Nerv Syst. 1986, In press
   Google Scholar