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Research Article

Calorie Restriction inhibits Sympathetic Nerve Activity via Anti-Oxidant Effect in the Rostral Ventrolateral Medulla of Obesity-Induced Hypertensive Rats

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Pages 240-245 | Received 31 Aug 2010, Accepted 12 Nov 2010, Published online: 24 Jun 2011

REFERENCES

  • Dandona P, Aljada A, Chaudhuri A, Mohanty P, Garg R. Metabolic syndrome: a comprehensive perspective based on interactions betweenobesity, diabetes, and inflammation. Circulation 2005;111:1448–1454.
  • Esler M, Straznicky N, Eikelis N, Masuo K, Lambert G, Lambert E. Mechanisms of sympathetic activation in obesity-related hypertension. Hypertension 2006;48:787–796.
  • Nagae A, Fujita M, Kawarazaki H, Matsui H, Ando K, Fujita T. Sympathoexcitation by oxidative stress in the brain mediates arterial pressure elevation in obesity-induced hypertension. Circulation 2009;119:978–986.
  • Dobrian AD, Davies MJ, Schriver SD, Lauterio TJ, Prewitt RL. Oxidative stress in a rat model of obesity-induced hypertension. Hypertension 2001;37:554–560.
  • Matsui H, Ando K, Kawarazaki H, Nagae A, Fujita M, Shimosawa T, Nagase M, Fujita T. Salt excess causes left ventricular diastolic dysfunction in rats with metabolic disorder. Hypertension 2008;52:287–294.
  • Smith AD, Brands MW, Wang MH, Dorrance AM. Obesity-induced hypertension develops in young rats independently of the renin-angiotensin-aldosterone system. Exp Biol Med (Maywood) 2006;231:282–287.
  • Holloszy JO, Fontana L. Caloric restriction in humans. Exp Gerontol 2007;42:709–712.
  • Pedrozo H, Bertrand HA, Herlihy JT. Caloric restriction alters arterialblood pressure and baroreflex responsiveness of the SHR. Age 1994;17:23–27.
  • Young JB, Mullen D, Landsberg L. Caloric restriction lowers bloodpressure in the SHR. Metab Clin Exp 1978;27:1711–1714.
  • Dampney RA. Functional organization of central pathways regulating the cardiovascular system. Physiol Rev 1994;74:323–364.
  • Guyenet PG. The sympathetic control of blood pressure. Nat Rev Neurosci 2006;7:335–346.
  • Kishi T, Hirooka Y, Kimura Y, Ito K, Shimokawa H, Takeshita A. Increased reactive oxygen species in rostral ventrolateral medulla contribute to neural mechanisms of hypertension in stroke-prone spontaneously hypertensive rats. Circulation 2004;109:3257–3262.
  • Kishi T, Hirooka Y, Konno S, Ogawa K, Sunagawa K. Angiotensin II type 1 receptor-activated caspase-3 through ras/mitogen-activated protein kinase/extracellular signal-regulated kinase in the rostral ventrolateral medulla is involved in sympathoexcitation in stroke-prone spontaneously hypertensive rats. Hypertension 2010;55:291–297.
  • Kishi T, Hirooka Y, Sakai K, Shigematsu H, Shimokawa H, Takeshita A. Overexpression of eNOS in the RVLM causes hypotension and bradycardia via GABA release. Hypertension 2001;38:896–901.
  • Hirooka Y, Sakai K, Kishi T, Takeshita A. Adenovirus-mediated gene transfer into the NTS in conscious rats. A new approach to examining the central control of cardiovascular regulation. Ann N Y Acad Sci 2001;940:197–205.
  • Hirooka Y, Kishi T, Sakai K, Shimokawa H, Takeshita A. Effect of overproduction of nitric oxide in the brain stem on the cardiovascular response in conscious rats. J Cardiovasc Pharmacol 2003;41:S119–S126.
  • Hirooka Y, Shigematsu H, Kishi T, Kimura Y, Ueta Y, Takeshita A. Reduced nitric oxide synthase in the brainstem contributes to enhanced sympathetic drive in rats with heart failure. J Cardiovasc Pharmacol 2003;42:S111–S115.
  • Sakai K, Hirooka Y, Shigematsu H, Kishi T, Ito K, Shimokawa H, Takeshita A, Sunagawa K. Overexpression of eNOS in brain stem reduces enhanced sympathetic drive in mice with myocardial infarction. Am J Physiol 2005;289:H2159–H2166.
  • Nozoe M, Hirooka Y, Koga Y, Sagara Y, Kishi T, Engelhardt JF, Sunagawa K. Inhibition of Rac1-derived reactive oxygen species in nucleus tractus solitarius decreases blood pressure and heart rate in stroke-prone spontaneously hypertensive rats. Hypertension 2007;50:62–68.
  • Nozoe M, Hirooka Y, Koga Y, Araki S, Konno S, Kishi T, Ide T, Sunagawa K. Mitochondria-derived reactive oxygen species mediate sympathoexcitation induced by angiotensin II in the rostral ventrolateral medulla. J Hypertens 2008;26:2176–2184.
  • Kishi T, Hirooka Y, Shimokawa H, Takeshita A, Sunagawa K. Atorvastatin reduces oxidative stress in the rostral ventrolateral medulla in stroke-prone spontaneously hypertensive rats. Clin Exp Hypertens 2008;30:1–9.
  • Kishi T, Hirooka Y, Ito K, Sakai K, Shimokawa H, Takeshita A. Cardivascular effects of overexpression of endothelial nitric oxide synthase in the rostral ventrolateral medulla in stroke-prone spontaneously hypertensive rats. Hypertension 2002;39:264–268.
  • Stocker SD, Meador R, Adams JM. Neurons of the rostral ventrolateral medulla contribute to obesity-induced hypertension in rats. Hypertension 2007;49:640–646.
  • Teske JA, Kotz CM. Effect of acute and chronic calonic restriction and metabolic glucoprivation on spontaneous physical activity in obesity-prone and obesity-resistance rats. Am J Physiol 2009;297:R176–R184.
  • Zhang X, Dong X, Ren J, Driscoll MJ, Culver B. High dietary fat induces NADPH oxidase-associated oxidative stress and inflammation in rat cerebral cortex. Exp Neurol 2005;191:318–325.
  • Zimmerman MC, Lazartigues E, Sharma RV, Davisson RL. Hypertension caused by angiotensin II infusion involves increased superoxide production in the central nervous system. Circ Res 2004;95:210–216.
  • Zimmerman MC, Lazartigues E, Lang JA, Sinnayah P, Ahmad IM, Spitz DR, Davisson RL. Superoxide mediates the actions of angiotensin II inthe central nervous system. Circ Res 2002;91:1038–1045.
  • Boustany CM, Bharadwaj K, Daugherty A, Brown DR, Randall DC, Cassis LA. Activation of the systemic and adipose renin-angiotensin system in rats with diet-induced obesity and hypertension. Am J Physiol 2004;287:R943–R949.
  • Delbosc S, Paizanis E, Magous R, Araiz C, Dimo T, Cristol JP, Cros G, Azay J. Involvement of oxidative stress and NADPH oxidase activation in the development of cardiovascular complications in a model of insulin resistance, the fructose-fed rat. Atherosclerosis 2005;179:43–49.
  • Dobrian AD, Schriver SD, Khraibi AA, Prewitt RL. Pioglitazone prevents hypertension and reduces oxidative stress in diet-induced obesity. Hypertension 2004;43:48–56.
  • Lauterio TJ, Davies MJ, DeAngelo M, Peyser M, Lee J. Neuropeptide Y expression and endogenous leptin concentrations in a dietary model of obesity. Obes Res 1999;7:498–505.
  • Ferguson AV, Washburn DL. Angiotensin II: a peptidergic neurotransmitter in central autonomic pathways. Prog Neurobiol 1998;54:169–192.

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