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Research Article

Erythropoietin, but Not Asialoerythropoietin or Carbamyl-Erythropoietin, Attenuates Monocrotaline-Induced Pulmonary Hypertension in Rats

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Pages 575-581 | Received 05 Feb 2012, Accepted 24 Mar 2012, Published online: 04 May 2012

REFERENCES

  • Fishman AP. Changing concepts of the pulmonary plexiform lesion. Physiol Res 2000; 49:485–492.
  • Limsuwan A, Pakakasama S, Hongeng S. Reversible course of pulmonary arterial hypertension related to bone marrow transplantation. Heart Vessels 2011; 26:557–561.
  • Galiè N, Manes A, Branzi A. Prostanoids for pulmonary arterial hypertension. Am J Respir Med 2003; 2:123–137.
  • Sitbon O, Humbert M, Jaïs X, . Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension. Circulation 2005; 111:3105–3111.
  • Galiè N, Ghofrani HA, Torbicki A, . Sildenafil citrate therapy for pulmonary arterial hypertension. N Engl J Med 2005; 353:2148–2157.
  • Chang SA, Jang SY, Ki CS, Kang IS, Kim DK. Successful bosentan therapy for pulmonary arterial hypertension associated with hereditary hemorrhagic telangiectasia. Heart Vessels 2011; 26:231–234.
  • Newman JH, Fanburg BL, Archer SL, . Pulmonary arterial hypertension: future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop. Circulation 2004; 109:2947–2952.
  • Hilliker KS, Bell TG, Roth RA. Pneumotoxicity and thrombocytopenia after single injection of monocrotaline. Am J Physiol 1982; 242:H573–H577.
  • Maiese K, Li F, Chong ZZ. New avenues of exploration for erythropoietin. JAMA 2005; 293:90–95.
  • Chong ZZ, Kang JQ, Maiese K. Erythropoietin is a novel vascular protectant through activation of Akt1 and mitochondrial modulation of cysteine proteases. Circulation 2002; 106:2973–2979.
  • Zhande R, Karsan A. Erythropoietin promotes survival of primary human endothelial cells through PI3K-dependent, NF-kappaB-independent upregulation of Bcl-xL. Am J Physiol Heart Circ Physiol 2007; 292:H2467–H2474.
  • Beleslin-Cokic BB, Cokic VP, Yu X, Weksler BB, Schechter AN, Noguchi CT. Erythropoietin and hypoxia stimulate erythropoietin receptor and nitric oxide production by endothelial cells. Blood 2004; 104:2073–2080.
  • Satoh K, Kagaya Y, Nakano M, . Important role of endogenous erythropoietin system in recruitment of endothelial progenitor cells in hypoxia-induced pulmonary hypertension in mice. Circulation 2006; 113:1442–1450.
  • van Albada ME, du Marchie Sarvaas GJ, Koster J, Houwertjes MC, Berger RM, Schoemaker RG. Effects of erythropoietin on advanced pulmonary vascular remodelling. Eur Respir J 2008; 31:126–134.
  • Umar S, Steendijk P, Ypey DL, . Novel approaches to treat experimental pulmonary arterial hypertension: a review. J Biomed Biotechnol 2010; 2010:702836.
  • Ozawa T, Toba K, Kato K, . Erythroid cells play essential roles in angiogenesis by bone marrow cell implantation. J Mol Cell Cardiol 2006; 40:629–638.
  • Mitsuma W, Ito M, Kodama M, . Cardioprotective effects of recombinant human erythropoietin in rats with experimental autoimmune myocarditis. Biochem Biophys Res Commun 2006; 344:987–994.
  • Dong YJ, Kung C, Goldwasser E. Receptor binding of asialoerythropoietin. J Cell Biochem 1992; 48:269–272.
  • Brines M, Grasso G, Fiordaliso F, . Erythropoietin mediates tissue protection through an erythropoietin and common beta-subunit heteroreceptor. Proc Natl Acad Sci USA 2008; 101:14907–14912.
  • Matsuda Y, Hoshikawa Y, Ameshima S, . Effects of peroxisome proliferator-activated receptor gamma ligands on monocrotaline-induced pulmonary hypertension in rats. Nihon Kokyuki Gakkai Zasshi 2005; 43:283–288.
  • Yoshida T, Hanawa H, Toba K, . Expression of immunological molecules by cardiomyocytes and inflammatory and interstitial cells in rat autoimmune myocarditis. Cardiovasc Res 2005; 68:278–288.
  • Weigel PH, Yik JH. Glycans as endocytosis signals: the cases of the asialoglycoprotein and hyaluronan/chondroitin sulfate receptors. Biochim Biophys Acta 2002; 1572:341–363.
  • McMahon FG, Vargas R, Ryan M, . Pharmacokinetics and effects of recombinant human erythropoietin after intravenous and subcutaneous injections in healthy volunteers. Blood 1990; 76:1718–1722.
  • Nasuno A, Toba K, Ozawa T, . Expression of coxsackievirus and adenovirus receptor in neointima of the rat carotid artery. Cardiovasc Pathol 2004; 13:79–84.
  • Runo JR, Loyd JE. Primary pulmonary hypertension. Lancet 2003; 361:1533–1544.
  • Zhao YD, Courtman DW, Deng Y, Kugathasan L, Zhang Q, Stewart DJ. Rescue of monocrotaline-induced pulmonary arterial hypertension using bone marrow-derived endothelial-like progenitor cells: efficacy of combined cell and eNOS gene therapy in established disease. Circ Res 2005; 96:442–450.
  • Heeschen C, Aicher A, Lehmann R, . Erythropoietin is a potent physiologic stimulus for endothelial progenitor cell mobilization. Blood 2003; 102:1340–1346.
  • Imai N, Higuchi M, Kawamura A, . Physicochemical and biological characterization of asialoerythropoietin. Suppressive effects of sialic acid in the expression of biological activity of human erythropoietin in vitro. Eur J Biochem 1990; 194:457–462.
  • Erbayraktar S, Grasso G, Sfacteria A, . Asialoerythropoietin is a nonerythropoietic cytokine with broad neuroprotective activity in vivo. Proc Natl Acad Sci USA 2003; 100:6741–6746.
  • Yokomaku Y, Sugimoto T, Kume S, . Asialoerythropoietin prevents contrast-induced nephropathy. J Am Soc Nephrol 2008; 19:321–328.
  • Lancrin C, Sroczynska P, Serrano AG, . Blood cell generation from the hemangioblast. J Mol Med 2010; 88:167–172.

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