Corticosterone-activated mineralocorticoid receptor contributes to salt-induced sympathoexcitation in pressure overload mice

References

• Levy D, Garrison RJ, Savage DD, et al. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Eng J Med 1990;322:1561–6
   PubMed Web of Science ®Google Scholar
• Schlaich MP, Kaye DM, Lambert E, et al. Relation between cardiac sympathetic activity and hypertensive left ventricular hypertrophy. Circulation 2003;108:560–5
   PubMed Web of Science ®Google Scholar
• Casale PN, Devereux RB, Milner M, et al. Value of echocardiographic measurement of left ventricular mass in predicting cardiovascular morbid events in hypertensive men. Ann Intern Med 1986;105:173–8
   PubMed Web of Science ®Google Scholar
• Iannini JP, Spinale FG. The identification of contributory mechanisms for the development and progression of congestive heart failure in animal models. J Heart Lung Transplant 1996;15:1138–50
   PubMed Web of Science ®Google Scholar
• Ito K, Hirooka Y, Sunagawa K. Acquisition of brain Na sensitivity contributes to salt-induced sympathoexcitation and cardiac dysfunction in mice with pressure overload. Circ Res 2009;104:1004–11
   PubMed Web of Science ®Google Scholar
• Ito K, Hirooka Y, Sunagawa K. Blockade of mineralocorticoid receptors improves salt-induced left-ventricular systolic dysfunction through attenuation of enhanced sympathetic drive in mice with pressure overload. J Hypertens 2010;8:1449–58
   Google Scholar
• Ito K, Hirooka Y, Nakano M, et al. Role of hypothalamic angiotensin type 1 receptors in pressure overload-induced mineralocorticoid receptor activation and salt-induced sympathoexcitation. Hypertens Res 2013;36:513–19
   PubMed Web of Science ®Google Scholar
• De Souza JT, Matsubara LS, Menani JV, et al. Higher salt preference in heart failure patients. Appetite 2012;58:418–23
   PubMed Web of Science ®Google Scholar
• Oshima N, Onimaru H, Takechi H, et al. Aldosterone is synthesized in and activates bulbospinal neurons through mineralocorticoid receptors and ENaCs in the RVLM. Hypertens Res 2013;36:504–12
   PubMed Web of Science ®Google Scholar
• Funder JW. Mineralocorticoid receptors: distribution and activation. Heart Fail Rev 2005;10:15–22
   PubMed Web of Science ®Google Scholar
• Fuller PJ, Young MJ. Mechanisms of mineralocorticoid action. Hypertension 2005;46:1227–35
   PubMed Web of Science ®Google Scholar
• Zhang ZH, Kang YM, Yu Y, et al. 11β-Hydroxysteroid dehydrogenase type 2 activity in hypothalamic paraventricular nucleus modulates sympathetic excitation. Hypertension 2006;48:127–33
   PubMed Web of Science ®Google Scholar
• Gomez-Sanchez EP, Gomez-Sanchez CE. Central regulation of blood pressure by the mineralocorticoid receptor. Mol Cell Endocrinol 2012;350:289–98
   PubMed Web of Science ®Google Scholar
• Lanz B, Kadereit B, Ernst S, et al. Angiotensin II regulates 11β-hydroxysteroid dehydrogenase type 2 via AT2 receptors. Kidney Int 2003;64:970–7
   PubMed Web of Science ®Google Scholar
• Ricketts ML, Stewart PM. Regulation of 11β-hydroxysteroid dehydrogenase type 2 by diuretics and the renin-angiotension-aldosterone axis. Clin Sci 1999;96:669–75
   PubMed Web of Science ®Google Scholar
• Lienhard D, Lauterburg M, Escher G, et al. High salt intake down-regulates colonic mineralocorticoid receptors, epithelial sodium channels and 11β-hydroxysteroid dehydrogenase type 2. PLoS ONE 2012;7:e37898
   PubMedGoogle Scholar
• Wei SG, Yu Y, Zhang ZH, et al. Angiotensin II-triggered p44/42 mitogen-activated protein kinase mediates sympathetic excitation in heart failure rats. Hypertension 2008;52:343–50
   Google Scholar
• Lowery EG, Spanos M, Navarro M, et al. CRF-1 antagonist and CRF-2 agonist decrease binge-like ethanol drinking in c57BL/6J mice independent of the HPA axis. Neuropsychopharmacology 2010;35:1241–52
   PubMed Web of Science ®Google Scholar
• Stranahan AM, Arumugam TV, Mattson MP. Lowering corticosterone levels reinstates hippocampal brain-derived neurotropic factor and Trkb expression without influencing deficits in hypothalamic brain-derived neurotropic factor expression in leptin receptor-deficient mice. Neuroendocrinology 2011;93:58–64
   PubMed Web of Science ®Google Scholar
• Ohtani T, Mano T, Hikoso S, et al. Cardiac steroidogenesis and glucocorticoid in the development of cardiac hypertrophy during the progression to heart failure. J Hypertens 2009;27:1074–83
   PubMed Web of Science ®Google Scholar
• Mihailidou AS, Loan Le TY, Mardini M, Funder JW. Glucocorticoids activate cardiac mineralocorticoid receptors during experimental myocardial infarction. Hypertension 2009;54:1306–12
   PubMed Web of Science ®Google Scholar
• Sheppard KE, Autelitano DJ. 11β-Hydroxysteroid dehydrogenase 1 transforms 11-dehydrocorticosterone into transcriptionally active glucocorticoid in neonatal rat heart. Endocrinology 2001;143:198–202
   Web of Science ®Google Scholar
• Zhang ZH, Yu Y, Wei SG, Felder RB. Aldosterone-induced brain MAPK signaling and sympathetic excitation are angiotensin II type-1 receptor dependent. Am J Physiol Heart Circ Physiol 2012;302:H742–51
   PubMed Web of Science ®Google Scholar
• Gomez-Sanchez EP, Ahmad N, Romero DG, Gomez-Sanchez CE. Is aldosterone synthesized within the rat brain? Am J Physiol Endocrinol Metab 2005;288:E342–6
   PubMed Web of Science ®Google Scholar
• Yu Y, Wei SG, Zhang ZH, et al. Does aldosterone upregulate the brain renin-angiotensin system in rats with heart failure? Hypertension 2008;51:727–33
   PubMed Web of Science ®Google Scholar
• Akers WS, Cross A, Speth R, et al. Renin-angiotensin system and sympathetic nervous system in cardiac pressure-overload hypertrophy. Am J Physiol Heart Circ Physiol 2000;279:H2797–806
   PubMed Web of Science ®Google Scholar
• Baker KM, Chernin MI, Wixson SK, Aceto JF. Renin-angiotensin system involvement in pressure-overload cardiac hypertrophy in rats. Am J Physiol Heart Circ Physiol 1990;259:H324–32
   PubMed Web of Science ®Google Scholar
• Hirano S, Imamura T, Onitsuka H, et al. Rapid increase in cardiac adrenomedullin gene expression caused by acute pressure overload – effect of renin-angiotensin system on gene expression. Circ J 2002;66:397–402
   PubMed Web of Science ®Google Scholar
• Leenen FH. The central role of the brain aldosterone – “ouabain” pathway in salt-sensitive hypertension. Biochim Biophys Acta 2010;1802:1132–9
   PubMed Web of Science ®Google Scholar
• Huang BS, White RA, Jeng AY, Leenen FH. Role of central nervous system aldosterone synthase and mineralocorticoid receptors in salt-induced hypertension in Dahl salt-sensitive rats. Am J Physiol Regul Integr Comp Physiol 2009;296:R994–1000
   PubMed Web of Science ®Google Scholar