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Review Article

Resistant hypertension: is renal denervation the current treatment of choice?

Pages 525-530 | Received 25 Nov 2013, Accepted 26 Dec 2013, Published online: 28 Mar 2014

References

  • World Health Organization. Global health risks: mortality and burden of disease attributable to selected major risks. Geneva: World Health Organization; 2009
  • Kearney PM, Whelton M, Reynolds K, et al. Global burden of hypertension: analysis of worldwide data. Lancet 2005;365:217–23
  • Go AS, Mozzaffarian D, Roger VL, et al. Heart disease and stroke statistics-2013 update: a report from the American Heart Association. Circulation 2013;127:e6–245
  • Sarafidis PA, Bakris GL. Resistant hypertension. An overview of evaluation and treatment. J Am Coll Cardiol 2008;52:1749–57
  • Calhoun DA, Jones DW, Textor S, et al. Resistant hypertension: diagnosis, evaluation, and treatment. A scientific statement from the American Heart Association Professional Educational Committee of the Council for High Blood Pressure Research. Hypertension 2008;51:1403–19
  • Schroeder C, Karsten H, Brinkmann J, et al. Truly refractory hypertension. Hypertension 2013;62:231–5
  • Persell SD. Prevalence of resistant hypertension in the United States, 2003–2008. Hypertension 2011;57:1076–80
  • Guyenet PG. The sympathetic control of blood pressure. Nat Rev Neurosci 2006;7:335–46
  • Fisher JP, Paton JFR. The sympathetic nervous system and blood pressure in humans: implications for hypertension. J Hum Hypertens 2012;26:463–75
  • Parati G, Esler M. The human sympathetic nervous system: its relevance in hypertension and heart failure. Eur Heart J 2012;33:1058–66
  • DiBona GF. Neural control of the kidney. Past, present, and future. Hypertension 2003;41:621–4
  • DiBona GF, Kopp UC. Neural control of renal function. Physiol Rev 1997;77:75–197
  • DiBona GF, Esler M. Translational medicine: the antihypertensive effect of renal denervation. Am J Physiol Regul Integr Comp Physiol 2010;298:R245–53
  • Esler M. The 2009 Carl Ludwig lecture: pathophysiology of the human sympathetic nervous system in cardiovascular diseases: the transition from mechanisms to medical management. J Appl Physiol 2010;108:227–37
  • Katholi RE, Rocha-Singh KJ. The role of sympathetic nerves in hypertension: has percutaneous renal denervation refocused attention on their clinical significance? Prog Cardiovasc Dis 2009;52:243–8
  • Converse RL Jr, Jacobsen TN, Toto RL, et al. Sympathetic overactivity in patients with chronic renal failure. N Engl J Med 1992;327:1912–18
  • Campese VM, Kogosov E, Koss M. Renal afferent denervation prevents the progression of renal disease in the renal ablation model of chronic renal failure in the rat. Am J Kidney Dis 1995;26:861–5
  • Campese VM, Ku E, Park J. Sympathetic renal innervation and resistant hypertension. Int J Hypertens 2011;2011:1–6
  • Morrissey DM, Brookes VS, Cooke WT. Sympathetectomy in the treatment of hypertension; review of 122 cases. Lancet 1953;1:403–8
  • Krum H, Schlaich M, Whitbourn R, et al. Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study. Lancet 2009;373:1275–81
  • Simplicity HTN-1 Investigators. Catheter-based renal sympathetic denervation for resistant hypertension. Durability of blood pressure reduction out to 24 months. Hypertension 2011;57:911–17
  • Simplicity HTN-2 Investigators. Renal sympathetic denervation in patients with treatment resistant hypertension (The Simplicity HTN-2 Trial): a randomized controlled trial. Lancet 2010;376:1903–9
  • Kandzari DE, Bhatt DL, Sobotka PA, et al. Catheter-based renal denervation for resistant hypertension: rationale and design of the SYMPLICITY HTN-3 trial. Clin Cardiol 2012;35:528–35
  • Worthley SG, Tsioufis CP, Worthley MI, et al. Safety and efficacy of a multi-electrode renal sympathetic denervation system in resistant hypertension: the EnligHTN 1 trial. Eur Heart J 2013;44:2132–40
  • Davis MI, Filion KB, Zang D, et al. Effectiveness of renal denervation therapy for resistant hypertension. A systematic review and meta-analysis. J Am Coll Cardiol 2013;62:231–41
  • Gosain P, Garimella PS, Hart PD, et al. Renal sympathetic denervation for treatment of resistant hypertension: a systematic review. J Clin Hypertens 2013;15:75–84
  • Ott C, Mahfoud F, Schmid A, et al. Renal denervation in moderate treatment resistant hypertension. J Am Coll Cardiol 2013;62:1880–6
  • Hering D, Mahfoud F, Walton AS, et al. Renal denervation in moderate to severe CKD. J Am Soc Nephrol 2012;23:1250–7
  • Schlaich MP, Bart B, Hering D, et al. Feasibility of catheter-based renal nerve ablation and effects on sympathetic nerve activity and blood pressure in patients with end-stage renal disease. Int J Cardiol 2013;168:2214–20
  • Ott C, Janka R, Schmid A, et al. Vascular and renal hemodynamic changes after renal denervation. Clin J Am Soc Nephrol 2013;8:1195–201
  • Dörr O, Liebetrau C, Möllmann H, et al. Renal sympathetic denervation does not aggravate functional or structural renal damage. J Am Coll Cardiol 2013;61:479–80
  • Mahfoud F, Cremers B, Janker J, et al. Renal hemodynamics and renal function after catheter-based renal sympathetic denervation in patients with resistant hypertension. Hypertension 2012;60:419–24
  • Brant MC, Mahfoud F, Reda S, et al. Renal sympathetic denervation reduces left ventricular hypertrophy and improves cardiac function in patients with resistant hypertension. J Am Coll Cardiol 2012;59:901–9
  • Mahfoud F, Schlaich M, Kindermann I, et al. Effect of renal sympathetic denervation on glucose metabolism in patients with resistant hypertension. A pilot study. Circulation 2011;123:1940–6
  • Witkowski A, Prejbisz A, Florczak E, et al. Effects of renal sympathetic denervation on blood pressure, sleep apnea course, and glycemic control in patients with resistant hypertension and sleep apnea. Hypertension 2011;58:599–65
  • Pokushalov E, Romanov A, Corbucci G, et al. A randomized comparison of pulmonary vein isolation with versus without concomitant renal artery denervation in patients with refractory symptomatic atrial fibrillation and resistant hypertension. J Am Coll Cardiol 2012;60:1163–70
  • Ukena C, Mahfoud F, Spies A, et al. Effects of renal sympathetic denervation on heart rate and atrioventricular conduction in patients with resistant hypertension. Int J Cardiol 2013;167:2846–51
  • Schlaich MP, Straznicky N, Grima M, et al. Renal denervation: a potential new treatment modality for polycystic ovary syndrome? J Hypertens 2011;29:991–8
  • Schlaich MP, Krum H, Sobotka PA, et al. Renal denervation and hypertension. Am J Hypertens 2011;24:635–42
  • Berog SC, Sobotka PA, Severt H. Renal denervation for hypertension. J Am Coll Cardiol Cardiovasc Intervent 2012;5:249–58
  • Mafeld S, Vasdev N, Haslam P. Renal denervation for treatment resistant hypertension. Ther Adv Cardiovasc Dis 2012;6:245–58
  • Pathak A, Girerd X, Azizi M, et al. Expert consensus: renal denervation for the treatment of hypertension. Diag Intervent Radiol 2012;93:386–94
  • Schmieder RE, Redon J, Grassi G, et al. ESH position paper: renal denervation-an interventional therapy of resistant hypertension. J Hypertens 2012;30:837–41
  • Jin Y, Persu A, Staessen JA. Renal denervation in the management of resistant hypertension: current evidence and perspective. Curr Opin Nephrol Hypertens 2013;22:511–18
  • Polimeni A, Curcio A, Indolfi C. Renal sympathetic denervation for treating resistant hypertension. Circ J 2013;77:857–63
  • Stouffer GA, DiBona GF, Patel A, et al. Catheter-based renal denervation in the treatment of resistant hypertension. J Mol Cell Cardiol 2013;62:18–23
  • Lakhanpal JP, Domanski MJ. Hypothesis: catheter-based renal sympathetic denervation should be the initial therapy for essential hypertension. Med Hypotheses 2012;78:482–4
  • Veelken R, Mann JFE. Renal sympathetic denervation as antihypertensive therapy – a reappraisal of first results. Nephrol Dial Transplant 2013;28:2698–701
  • Lohmeier TE, Hildebrandt DA, Dwyer TM, et al. Renal denervation does not abolish sustained baroreflex-mediated reductions in arterial pressure. Hypertension 2007;49:373–9
  • Kaltenbach B, Id D, Franke JC, et al. Renal artery stenosis after renal sympathetic denervation. J Am Coll Cardiol 2012;60:2694–5
  • Elmula FEMF, Hoffmann P, Fossum E, et al. Renal sympathetic denervation in patients with treatment-resistant hypertension after witnessed intake of medication before qualifying ambulatory blood pressure. Hypertension 2013;62:526–32

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