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Original Articles

Activation of upregulated angiotensin II type 2 receptors decreases carotid pulse pressure in rats with suprarenal abdominal aortic coarctation

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Pages 271-279 | Received 23 Jun 2014, Accepted 01 Aug 2014, Published online: 01 Oct 2014

References

  • de Gasparo M, Catt KJ, Inagami T, Wright W, Unger TH. International Union of Pharmacology. XXIII. The angiotensin II receptors. Pharmacol Rev 2000;52:415–72
  • Kim S, Iwao H. Molecular and cellular mechanisms of angiotensin II-mediated cardiovascular and renal diseases. Pharmacol Rev 2000;52:11–34
  • Lemarié CA, Schiffrin EL. The angiotensin II type 2 receptor in cardiovascular disease. J Renin Angiotensin Aldosterone Syst 2010;11:19–31
  • Li Y, Li XH, Yuan H. Angiotensin II type-2 receptor-specific effects on the cardiovascular system. Cardiovasc Diagn Ther 2012;2:56–62
  • Savoia C, D'Agostinoa M, Lauria F, Volpea M. Angiotensin type 2 receptor in hypertensive cardiovascular disease. Curr Opin Nephrol Hypertens 2011;20:125–32
  • Yayama K, Horii M, Hiyoshi H, et al. Up-regulation of angiotensin II type 2 receptor in rat thoracic aorta by pressure-overload. J Pharmacol Exp Ther 2004;308:736–43
  • Hiyoshi H, Yayama K, Takano M, Okamoto H. Stimulation of cyclic GMP production via AT2 and B2 receptors in the pressure-overloaded aorta after banding. Hypertension 2004;43:1258–63
  • Yayama K, Hiyoshi H, Imazu D, Okamoto H. Angiotensin II stimulates endothelial NO synthase phosphorylation in thoracic aorta of mice with abdominal aortic banding via type 2 receptor. Hypertension 2006;48:958–64
  • Hiyoshi H, Yayama K, Takano M, Okamoto H. Angiotensin type 2 receptor-mediated phosphorylation of eNOS in the aortas of mice with 2-kidney, 1-clip hypertension. Hypertension 2005;45:967–73
  • Fitch RM, Vergona R, Sullivan ME, Wang Y-X. Nitric oxide synthase inhibition increases aortic stiffness measured by pulse wave velocity in rats. Cardiovasc Res 2001;51:351–8
  • Fitch RM, Rutledge JC, Wang Y-X, et al. Synergistic effect of angiotensin II and nitric oxide synthase inhibitor in increasing aortic stiffness in mice. Am J Physiol Heart Circ Physiol 2006;290: H1190–8
  • Safar ME, Laurent P. Pulse pressure and arterial stiffness in rats: comparison with humans. Am J Physiol Heart Circ Physiol 2003;285:H1363–9
  • Nichols WW, O'Rourke MF. McDonald's blood flow in arteries. Theoretical, experimental and clinical principles. London: Hodder Arnold Publishers; 2005
  • Barber MN, Sampey DB, Widdop RE. AT(2) receptor stimulation enhances antihypertensive effect of AT(1) receptor antagonist in hypertensive rats. Hypertension 1999;34:1112–16
  • Siragy HM, de Gasparo M, Carey RM. Angiotensin type-2 receptor mediates valsartan-induced hypotension in conscious rats. Hypertension 2000;35:1074–7
  • Carey RM, Howell NL, Jin X-H, Siragy HM. 2001. Angiotensin type 2 receptor-mediated hypotension in angiotensin type-1 receptor-blocked rats. Hypertension 2001;38:1272–7
  • Li XC, Widdop RE. AT2 receptor-mediated vasodilatation is unmasked by AT1 receptor blockade in conscious SHR. Br J Pharmacol 2004;142:821–30
  • Ozono R, Matsumoto T, Shingu T, et al. Expression and localization of angiotensin subtype receptor proteins in the hypertensive rat heart. Am J Physiol Regul Integr Comp Physiol 2000;278:R781–9
  • Karpe PA, Gupta J, Marthong RF, et al. Insulin resistance induces a segmental difference in thoracic and abdominal aorta: differential expression of AT1 and AT2 receptors. J Hypertension 2012;30:132–46
  • Yu L, Zheng M, Wang W, et al. Developmental changes in AT1 and AT2 receptor-protein expression in rats. J Renin Angiotensin Aldosterone Syst 2010;11:214–21
  • Yayama K, Okamoto H. Angiotensin II-induced vasodilation via type 2 receptor: role of bradykinin and nitric oxide. Int Immunopharmacol 2008;8:312–18
  • Paul M, Mehr AP, Kreutz R. Physiology of local renin-angiotensin systems. Physiol Rev 2006;86:747–803
  • Macari D, Whitebread S, Cumin F, et al. Renal actions of the angiotensin AT2 receptor ligands CGP 42112 and PD 123319 after blockade of the renin-angiotensin system. Eur J Pharmacol 1994;259:27–36
  • Göhlke P, Pees C, Unger T. AT2 receptor stimulation increases aortic cyclic GMP in SHRSP by a kinin-dependent mechanism. Hypertension 1998;31:349–55
  • Li JS, Touyz RM, Schiffrin EL. Effects of AT1 and AT2 angiotensin receptor antagonists in angiotensin II-infused rats. Hypertension 1998;31:487–92
  • Champion HC, Czapla MA, Kadowitz PJ. Responses to angiotensin peptides are mediated by AT1 receptors in the rat. Am J Physiol Endocrinol Metab 1998;274:115–23
  • Schuijt MP, deVries R, Saxena PR, Dauser AH. No vasoactive role of the angiotensin II type 2 receptor in normotensive Wistar rats. J Hypertens 1999;17:1879–84
  • Santos RA, Ferreira AJ, Verano-Braga T, Bader M. Angiotensin-converting enzyme 2, angiotensin-(1-7) and Mas: new players of the renin–angiotensin system. J Endocrinol 2013;216:R1–17

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