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Clinical and Experimental Hypertension. Part A: Theory and Practice Volume 6, 1984 - Issue 6
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Original Article

The Effects of Chronic Treatment with Captopril in Spontaneously Hypertensive Rats (SHR) and their Offspring

M Chadelaud Department of Pharmacology, UER of Medicine of Rouen, B.P. 97, 76800, St-Etienne du Rouvray, France
,
N Moore Department of Pharmacology, UER of Medicine of Rouen, B.P. 97, 76800, St-Etienne du Rouvray, France
,
C Berland Department of Pharmacology, UER of Medicine of Rouen, B.P. 97, 76800, St-Etienne du Rouvray, France
,
C Saligaut Department of Pharmacology, UER of Medicine of Rouen, B.P. 97, 76800, St-Etienne du Rouvray, France
,
M Daoust Department of Pharmacology, UER of Medicine of Rouen, B.P. 97, 76800, St-Etienne du Rouvray, France
,
P Chretien Department of Pharmacology, UER of Medicine of Rouen, B.P. 97, 76800, St-Etienne du Rouvray, France
&
F Boismare Department of Pharmacology, UER of Medicine of Rouen, B.P. 97, 76800, St-Etienne du Rouvray, France
 show all
Pages 1179-1186 | Published online: 03 Jul 2009

References

  • Antonaccio M J, Rubin B, Horowitz Z P, Laffan R J, Goldberg M E, High J P, Harris D N, Zaidi I. Effects of chronic treatment with captopril (SQ 14, 225), an orally active inhibitor of angiotensin I-converting enzyme, in spontaneously hypertensive rats. Japan J. Pharmacol 1979; 29: 285
  • Byron J B, Wilson C A. A plethysmographic method for measu ring blood pressure in the rat. J. Physiol 1938; 93: 301
  • “Committee on Care and Use of SHR” : Spontaneously hypertensive rats : Guidelines for Breeding. Care and Use - Ilar News XIX 1976; 3
  • Ferrone R A, Antonaccio M J. Prevention of the development of spontaneous hypertension in rats by captopril (SQ 14, 225) European. J. Pharmacol 1979; 60: 131
  • Giudicelli J F, Freslon J L, Glasson S, Richer C. Captopril and hypertension development in the SHR. Clin, and Exper. Hyper 1980; 2((6))1083
  • Haber E, Koerner T, Page L B, Kliman B, Purnode A. Application of a radioimmunoassay for angiotensin I to the physiologic measurements of plasma renin activity in normal human subjects. J. Clin. Endocr. Met 1969; 29: 1349
  • Mikami H, Ogihara T, Ohde H, Naka T, Kumahara Y. Evaluation of hypotensive mechanisms of captopril in addition to its inhibition of the converting enzyme in spontaneously hypertensive rats. Japan Circ. J 1982; 46: 1154
  • Moore N, Chadelaud M, Gugi B, Saligaut C, Berland C, Chretien P, Daoust M, Boismare F. The effects of nicergoline on spontaneously hypertensive rats and their offspring. Clin, and Exper. Hyper. A 1983; 5(4)613
  • Okamoto K, Aoki K. Development of a strain of spontaneously hypertensive rats. Japan Circ. J 1963; 27: 282
  • Rubin B, Antonaccio M J. “Captopril”, in Pharmacology of Antihypertensive Drugs, A Scriabine. Raven Press, New York 1980; 21

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