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Clinical and Experimental Hypertension. Part A: Theory and Practice Volume 6, 1984 - Issue 1-2
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Original Article

Mechanism for Hypotensive Action of Angiotensin Converting Enzyme Inhibitors

C. I. Johnston Monash University, Department of Medicine Prince Henry's Hospital, Melbourne, Australia
,
B. Jackson Monash University, Department of Medicine Prince Henry's Hospital, Melbourne, Australia
,
R. Cubela Monash University, Department of Medicine Prince Henry's Hospital, Melbourne, Australia
&
L. Arnolda Monash University, Department of Medicine Prince Henry's Hospital, Melbourne, Australia
Pages 551-561 | Published online: 03 Jul 2009

References

  • Brunner H R, Gavras H, Waeber B. Clincai use of an orally acting converting enzyme inhibitor captopril. Hypertension 1980; 2: 558–564
  • Johnston C I, McGrath B P, Matthews P G, Jackson B. Treatment of hypertension with angiotensin converting enzyme inhibitors. Clin. & Exp. Pharmacol. & Physiol. Suppl. 1982; 7: 135–144
  • Ondetti M A, Rubin B, Cushman D W. Design of specific inhibitors of angiotensin-converting enzyme. a new class of orally antihypertensive agents 1977; 196: 4411–444
  • Waeber B, Brunner H R, Curtet A L, Turini G A, Gavras H. Discrepancy between antihypertensive effect and angiotensin converting enzyme inhibition by captopril. Hypertension. 1980; 2: 2236–242
  • Millar J A, McGrath B P, Matthews P G, Johnston C I. Acute effects of captopril on blood pressure and circulating hormone levels in salt replete and depleted normal subjects and essential hypertensive patients. Clin. Sci. 1981; 61: 75–83
  • Roulston J E, MacGregor G A. The measurement of angiotensin converting enzyme in subjects receiving Captopril. New Eng. J. Med. 1980; 303: 397
  • Cohen M L, Kurz K. Captopril & MK421: stability in storage distribution to central nervous system and onset of activity. Federation Proc. 1983; 42: 171–175
  • Jackson B, McGrath B P, Johnston C I. Correlation between angiotensin converting enzyme inhibition and the acute hypotensive response to MK421 in essential hypertension. Clin. & Exp. Pharmacol. & Physiol. 1982; 7: 99–104, supp
  • Gavras H, Waeber B, Gavras I, Biollaz J, Brunner H R, Davis R O. Antihypertensive effect of the new oral angiotensin converting enzyme inhibition MK421. Lancet 1981; ii: 543–546
  • Johnston C I, Jackson B, McGrath B P, Matthews P G, Arnolda L. Relationship of antihypertensive effect of enalapril to serum MK422 levels and angiotensin converting enzyme inhibition. J. Hypertension 1963, (in press)
  • Ulm E H. Enalapril maleate (MK421) a potent nonsulphydryl angiotensin-converting-enzyme inhibitor: Absorption disposition & metabolism in man. Drug Metabolism Rev. 1983; 14: 99–110
  • Johnston C I, Millar J A, Casley D J, McGrath B P, Matthews P G. Hormonal responses to angiotensin blockade. Comparison between receptor antagonism and converting enzyme inhibition. Circ. Res., Suppl. 1980; 1: 1128–1134
  • Fyhrquist F, Forslund T, Tikkaneen I, Gröhhage-Risken. Induction of angiotensin I converting enzyme in rat lung with captopril (SQ14,225). Eur. J. Pharmacol. 1980; 67: 473–475

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