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Clinical and Experimental Hypertension. Part A: Theory and Practice Volume 9, 1987 - Issue sup1
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Original Article

Blood Pressure Changes in SPO Ntaneously Hypertensive and Normotensive Rats with Neonatal Streptozotocin Induced Type 2 Diabetes

M Iwase Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, 812, Japan
,
M Kikuchi Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, 812, Japan
,
K Nunoi Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, 812, Japan
,
M Wakisaka Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, 812, Japan
,
Y Maki Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, 812, Japan
,
S Sadoshima Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, 812, Japan
&
M Fujishima Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, 812, Japan
 show all
Pages 2157-2168 | Published online: 03 Jul 2009

References

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  • Modan M, Halkin H, Almog S, Lusky A, Eshkol A, Shefi M, Shitrit A, Fuchs Z. Hyperinsulinemia. A link between hypertension obesity and glucose intolerance. J Clin Invest 1985; 75: 809–817
  • Kawashima H, Igarashi T, Nakajima Y, Akiyama Y, Usuki K, Ohtake S. Chronic hypertension induced by streptozotocin in rats. Naunyn-Schmiedeberg's Arch Pharmacol 1978; 305: 123–126
  • Kohler L, Boillat N, Luthi P, Atkinson J, Peters-Haefeli L. Influence of streptozotocin-induced diabetes on blood pressure and on renin formation and release. Naunyn-Schmiedeberg's Arch Pharmacol 1980; 313: 257–261
  • Bunag R D., Tomita T, Sasaki S. Streptozotocin diabetic rats are hypertensive despite reduced hypothalamic responsiveness. Hypertension 1982; 4: 556–565
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  • Lams S G., Wexler B C. Alloxan diabetes in spontaneously hypertensive rats. Gravimetric, metabolic and histopathological alterations. Br J exp Path 1977; 58: 177–199
  • Somani P, Singh H P., Saini R K., Rabinovitch A. Streptozotocin-induced diabetes in the spontaneously hypertensive rat. Metabolism 1979; 28: 1075–1077
  • Cavaliere T A., Taylor D G., Kerwin L J., Antonaccio M J. Cardiovascular effects of alloxan diabetes in normotensive and spontaneously hypertensive rats. Pharmacology 1980; 20: 211–223
  • Rodgers R L., Breault P H., Sessa W C., Jr, Chichester C O. Depressor effect of diabetes in spontaneously hypertensive rat. Role of vascular reactivity and prolyl hydroxylase and lysyl oxidase activities. Life Science 1985; 37: 2237–2247
  • Iwase M, Kikuchi M, Nunoi K, Wakisaka M, Maki Y, Sadoshiraa S, Fujishima M. A new model of type 2 (non-insulin-dependent) diabetes mellitus in spontaneously hypertensive rats. Diabetes induced by neonatal streptozotocin treatment. Diabetologia 1986; 29: 808–811
  • Iwase M, Kikuchi M, Nunoi K, Wakisaka M, Maki Y, Sadoshima S, Fujishima M. Diabetes induced by neonatal streptozotocin treatment in spontaneously hypertensive and noriaotensive rats. Metabolism

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