Central and Peripheral Inhibition of Angiotensin Converting Enzyme (ACE) in the Shr: Correlation with the Antihypertensive Activity of ACE Inhibitors

Jon A. Norman Research Department, Pharmaceuticals Division, CIBA-GEIGY Corporation, Summit, New Jersey, 07901, USA

Monique Lehmann Research Department, Pharmaceuticals Division, CIBA-GEIGY Corporation, Summit, New Jersey, 07901, USA

Frank R. Goodman Research Department, Pharmaceuticals Division, CIBA-GEIGY Corporation, Summit, New Jersey, 07901, USA

Bryce W. Barclay Research Department, Pharmaceuticals Division, CIBA-GEIGY Corporation, Summit, New Jersey, 07901, USA

Mark B. Zimmerman Research Department, Pharmaceuticals Division, CIBA-GEIGY Corporation, Summit, New Jersey, 07901, USA

References

Cohen M. L., Kurz K. D. Angiotensin converting enzyme inhibition in tissues from spontaneously hypertensive rats after treatment with captopril or MK-421. J. Pharmacol. Exp. Ther. 1982; 220: 63–69
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Unger T., Kaufmann-Bühler I., Schölkens B., Ganten O. Brain converting enzyme inhibition: A possible mechanism for the antihypertensive action of captopril in spontaneously hypertensive rats. Eur. J. Pharmacol. 1981; 70: 467–478
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Central and Peripheral Inhibition of Angiotensin Converting Enzyme (ACE) in the Shr: Correlation with the Antihypertensive Activity of ACE Inhibitors

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Central and Peripheral Inhibition of Angiotensin Converting Enzyme (ACE) in the Shr: Correlation with the Antihypertensive Activity of ACE Inhibitors

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