Overview: Studies on Spontaneous Hypertension - Development from Animal Models Toward Man

References

• Okamoto K., Aoki K. Development of a strain of spontaneously hypertensive rats. Jpn. Circ. J. 1963; 27: 282–293
   PubMedGoogle Scholar
• Yamori Y. Development of the spontaneously hypertensive rats (SHR) and of various spontaneous rat models, and their implications. Experimental and Genetic Models of Hypertension, W. de Jong. Elsevier, Amsterdam 1984; 224–239
   Google Scholar
• Yamori Y., Nagaoka A., Okamoto K. Importance of genetic factors in hypertensive cerebrovascular lesions: an evidence obtained by successive selective breeding of stroke-prone and-resistant SHR. Jpn. Circ. J. 1974; 38: 1095–1100
   PubMedGoogle Scholar
• Okamoto K., Yamori Y., Nagaoka A. Establishment of the stroke-prone SHR. Circ. Res. 1974; 34/35(Suppl. I)143–153
   Google Scholar
• Yamori Y. The stroke-prone spontaneously hypertensive rats: contribution to risk factor analysis and prevention of hypertensive diseases. Experimental and genetic models of hypertension, W. de Jong. Elsevier, Amsterdam 1984; 240–255
   Google Scholar
• Yamori Y. Physiopathology of the various strains of spontaneously hypertensive rats. Hypertension, J Genest, O. Kuchel, P. Hamet, et al. McGraw-Hill, Montréal 1983; 556–581
   Google Scholar
• Yamori Y. Prediction and preventive pathology of cardiovascular diseases. Acta Pathol. Jpn. 1989; 39: 683–705
   PubMedGoogle Scholar
• Yamori Y., Horie R., Nara Y., Tagami M., Kihara M., Mano M., Ishino H. Pathogenesis and dietary prevention of cerebrovascular diseases in animal models and epidemiological evidence for the applicability in man. Prevention of Cardiovascular Diseases: An Approach to Active Long Life, Y. Yamori, C. Lenfant. Elsevier, Amsterdam 1987; 163–177
   Google Scholar
• Yamori Y., Kihara M., Nara Y. Myocardial-ischemic rats (MIR): Coronary vascular alteration induced by a lipid-rich diet. Atherosclerosis 1982; 42: 15–20
   PubMed Web of Science ®Google Scholar
• Yamori Y., Tsubouchi T., Utagawa N., Nara Y., Mano M., Kihara M., Horie R. Spontaneously coronary vascular alterations in myocardial ischemic rats. J. Hypertension 1986; 4(Suppl. 3)S45–S46
   Google Scholar
• Yamori Y. Neural and non-neural mechanisms in spontaneous hypertension. Clin. Sci. Mol. Med. 1976; 51: 431s–434s
   Google Scholar
• Yamori Y., Ikeda K., Kulakowski E. C., McCarty R., Lovenberg W. Enhanced sympathetic-adrenal medullary response to cold exposure in spontaneously hypertensive rats. J. Hypertension 1985; 3: 63–66
   PubMed Web of Science ®Google Scholar
• Yamori Y., Mano M., Kihara M., Nara Y., Horie R., Kunishi H., Endo J. Studies on prediction of hypertension in spontaneously hypertensive rats (SHR). (1) Application of cold-induced adrenomedullary hyperresponsivness into men. Jpn. Heart J. 1985; 26: 630
   Google Scholar
• Yamori Y., Mori C., Nishio T., Ooshima A., Horie R., Ohtka N., Soeda T., Saito M., Abe K., Nara Y., Nakao Y., Kihara M. Cardiac hypertrophy in early hypertension. Am. J. Cardiol. 1979; 44: 964–969
   PubMed Web of Science ®Google Scholar
• Nishio T., Mori C., Saito M., Soeda T., Abe K., Nakao Y. Left ventricular hypertrophy in early hypertensive children: Its importance as a risk factor for hypertension. Shimane J. Med. Sci. 1979; 3: 71–79
   Google Scholar
• Nishio T., Mori C., Saito M. The relationship between blood pressure and left ventricular muscle volume in normal children and adolescents: The Shimane Heart Study. Jpn. Circ. J. 1984; 48: 1402–1405
   PubMedGoogle Scholar
• Yamori Y., Nara Y., Kihara M., Horie R., Ooshima A. Sodium and other dietary factors in experimental and human hypertension - the Japanese experience. Frontiers in Hypertension Research, J. H. Laragh, F. R. Bühler, D. W. Seldin. Springer-Verlag, New York/Heidelberg/Berlin 1981; 46–48
   Google Scholar
• Yamori Y., Horie R., Nara Y., Kihara M., Fujiwara K., Nabika T., Mano M., Ikeda K. Nutritional causation and prevention of cardiovascular diseases - experimental evidence in animal models and man. Nutritional Prevention of Cardiovascular Disease, W. Lovenberg, Y. Yamori. Academic Press, Orlando 1984; 37–51
   Google Scholar
• Folkow B., Hallbäck M., Lundgren Y., Silvertson R., Weiss L. Importance of adaptive changes in vascular design for establishment of primary hypertension studied in man and in spontaneously hypertensive rats. Circ. Res. 1975; 32/33(Suppl. I)2
   Google Scholar
• Yamori Y. Contribution of cardiovascular factors to the development of hypertension in spontaneously hypertensive rats. Jpn. Heart J. 1974; 15: 194–196
   PubMedGoogle Scholar
• Yamori Y. Interaction of neural and nonneural factors in the pathogenesis of spontaneous hypertension. The Nervous System in Arterial Hypertension, S. Julius, M. Esler. C. C. Thomas, Springfield 1976; 17–50
   Google Scholar
• Yamori Y., Igawa T., Kanbe T., Kihara M., Nara Y., Horie R. Mechanisms of structural vascular changes in genetic hypertension: Analyses on cultured vascular smooth muscle cells from spotnaneously hypertensive rats. Clin. Sci. 1981; 61(Suppl. 7)121s–123s
   PubMedGoogle Scholar
• Yamori Y., Igawa T., Kanbe T., Nara Y., Tagami M. Enhanced growth rate of cultured vascular smooth muscle cells from spontaneously hypertensive rats. Heart Vessels 1988; 4: 94–99
   PubMedGoogle Scholar
• Yamori Y., Kanbe T., Igawa T., Kihara M., Nara Y., Horie R. Electrolyte balance in cultured smooth muscle cells from the aorta of SHR. Hypertensive Mechanisms: the Spontaneously Hyeprtensive Rat as a Model to Study Human Hypertension, W. Rascher, D. Clough, D. Ganten. F. K. Schattauer Verlag, Stuttgart/New York 1982; 281–284
   Google Scholar
• Postnov Y. V., Orlov S. N. Cell membrane alteration as a source of primary hypertension. J. Hypertension 1984; 2: 1–6
   PubMedGoogle Scholar
• Yamori Y., Nara Y., Horie R. Ion permeability of erythrocyte membrane in SHR. Jpn. Heart J. 1977; 18: 604–605
   PubMedGoogle Scholar
• Nabika T., Nara Y., Endo J., Yamori Y. Effects of Na+ on kinetics of cell proliferation in cultured vascular smooth muscle cells. J. Hypertension 1986; 4(Suppl. 6)S303–S305
   Google Scholar
• Yamori Y., Horie R. Developmental course of hypertension and regional cerebral blood flow in stroke-prone spontaneously hypertensive rats. Stroke 1977; 8: 456–461
   PubMed Web of Science ®Google Scholar
• Yamori Y., Horie R. Experimental studies on the pathogenesis and prophylaxis of stroke in stroke-prone spotaneously hypertensive rats (SHR) (II) Prophylactic effect of moderate control of blood pressure on stroke. Jpn. Circ. J. 1975; 39: 616–621
   PubMedGoogle Scholar
• Rogers R. L., Meyer J. S., Mortel K. F. Additional predisposing risk factors for atherothrombotic cerebroascular diseases among treated hypertensive volunteers. Stroke 1987; 18: 335–341
   PubMed Web of Science ®Google Scholar
• Tagami M., Nara Y., Kubota A., Sunaga T., Maezawa H., Fujino H., Yamori Y. Ultrastructural characteristics of occluded perforating arteries in stroke-prone spontaneously hypertensive rats. Stroke 1987; 18: 733–740
   PubMed Web of Science ®Google Scholar
• Gown A. M., Tsukuda T., Ross R. Human atherosclerosis: immunocytochemical analysis of the cellular composition of human atherosclerotic lesions. Am. J. Pathol. 1986; 125: 191–207
   PubMed Web of Science ®Google Scholar
• Yamori Y., Nara Y., Tagami M., Mano M., Kihara M., Fujiwara K., Horie R., Kamino K. Common cellular disposition to hypertension and atherosclerosis. J. Hypertension 1984; 2(Suppl. 3)213–215
   Google Scholar
• Nara Y., Shimizu S., Yamada K., Sawamura M., Mano M., Kobayashi A., Horie R., Yamori Y. Lipid accumulation in cultured vascular smooth muscle cells (VSMC) from the aorta of stroke-prone SHR (SHRSP) under hypoxic condition. Jpn. Heart J. 1988; 29: 520
   Google Scholar
• Yamori Y. Environmental influences on the development of hypertensive vascular diseases in SHR and related models, and their relation to human diseases. New Trends in Arterial Hypertension, M. Worcel, J. P. Bonvalet, S. Z. Langer, J. Menard, J. Sassard. Elsevier, Amsterdam/New York/Oxford 1981; 305–320
   Google Scholar
• Tobian L., Lang J., Ulm K., Wold L., Iwai J. Potassium reduces cerebral hemorrhage and death rate in hypertensive rats, even when blood pressure is not lowered. Hypertension 1985; 7(suppl. 1)I110–I114
   PubMedGoogle Scholar
• Yamori Y., Nara Y., Ikeda K., Tsuchikura S., Eguchi T., Mano M., Horie R., Sugahara T. Recent advances in experimental studies on dietary prevention of cardiovascular diseases. New Horizons in Preventing Cardiovascular Diseases, Y. Yamori, T. Strasser. Elsevier, Amsterdam 1989; 1–11
   Google Scholar
• Horie R., Morioka S., Fujiwara K., Nagase H., Sano K., Kihara M., Nara Y., Moriyama K., Yamori Y. Shimane Intervention Study - effect of reducing dietary sodium to potassium ratio on blood pressure in the aged people. Nutritional Prevention of Cardiovascular Disease, W. Lovenberg, Y. Yamori. Academic Press, Orlando 1984; 211–216
   Google Scholar
• Yamori Y., Horie R., Akiguchi I., Ohtaka M., Nara Y., Fukase M. New models of SHR for studies on stroke and atherogenesis. Clin. Exp. Pharmacol. Physiol. 1976, Supl. 3: 199–203
   PubMedGoogle Scholar
• Yamori Y., Wang H., Ikeda K., Kihara M., Nara Y., Horie R. Role of sulfur amino acids in the prevention and regression of cardiovascular diseases. Sulfur Amino Acids: Biochemical Aspects. Alan R, K. Kuriyama, R. J. Huxtable, H. Iwata. Liss, Inc., New York 1983; 103–115
   Google Scholar
• Ikeda K., Nara Y., Horie R., Yamori Y. Diets modify pressor and catecholamine hypertensive rats (SHRSP). New Horizons in Preventing Cardiovascular Diseases, Y. Yamori, T. Strasser. Elsevier, Amsterdam 1989; 23–25
   Google Scholar
• CARDAIC. (Cardiovascular Diseases and Alimentary Comparison) study protocol. WHO Collaborating Center for Research on Primary Prevention of Cardiovascular Diseases. WHO, Shimane-Geneva 1986
   Google Scholar
• CARDIAC Study Group. Purpose and design of the CARDIAC Study: Hypertension and biological dietary markers in urine and blood - a progress from the CARDIAC Study Group. New Horizons in Preventing Cardiovascular Diseases, Y. Yamori, T. Strasser. Elsevier, Amsterdam 1989; 111–126
   Google Scholar
• Yamori Y. (on behalf of CARDIAC Study Group) Preliminary report of CARDIAC Study: Cross-sectional multicenter study on dietary factors of cardiovascular diseases. Clin. Exp. Hypertension 1989; 11: 957–972
   Web of Science ®Google Scholar
• Yamori Y., Nara Y., Mizushima S., Mano M., Sawamura M., Kihara M., Horie R., Hatano S. International cooperative study on the relationship between dietary factors and blood pressure: a report from the cardiovascular diseases and alimentary comparison study. J. Cardiovasc. Pharmacol. 1990; 16(Suppl. 8)s43–s47
   PubMedGoogle Scholar
• Fukuoka M., Yamori Y. A proposal for indirect and objective blood pressure measurement in adults. Prevention of cardiovascular disases: an approach to active long life, Y. Yamori, C. Lenfant. Elsevier, Amsterdam 1987; 127–137
   Google Scholar
• Yamori Y., Nara Y., Kihara M., Mano M., Horie R. Simple method for sampling consecutive 24-hour urine for epidemiological and clinical studies. Clin. Exp. Hypertension 1984; 6: 1161–1167
   Web of Science ®Google Scholar
• Nara Y., Kihara M., Mano M., Horie R., Yamori Y. “Aliquot cups”, simple method for collecting consecutive 24-hour urine samples for epidemiological and clinical studies. Nutritional Prevention of Cardiovascular Disease, W. Lovenberg, Y. Yamori. Academic Press, Orlando 1984; 211–216
   Google Scholar
• Yamori Y. The salt balance in Asia. Salt and Hypertension, R. Retting, D. Ganten, F. Luft. Springer-Verlag, Heidelberg 1988; 319–328
   Google Scholar
• Mtabaji J. P., Nara Y., Moriguchi Y., Yamori Y. Diet and hypertension in Tanzania. J. Cardiovasc. Pharmacol. 1990; 16(Suppl. 8)S3–S5
   PubMedGoogle Scholar