9
Views
5
CrossRef citations to date
0
Altmetric
Original Article

Renin and Renin Inhibition in Anephric Man

, , , &
Pages 289-306 | Received 25 Mar 1992, Accepted 08 Sep 1992, Published online: 03 Jul 2009

References

  • Frohlich E.D., Iwata T., Sasaki O. Clinical and physiologic significance of local tissue renin-angiotensin systems. Am J Med. 1989; 87(Suppl 6B)19S–23S
  • Skinner S.L. Improved assay methods for renin “concentration” and “activity” in human plasma. Circ Res. 1967; 20: 391–402
  • Capelli J.P., Wesson L.G., Aponte G.E., Faraldo C., Jaffe E. Characterization and source of a renin-like enzyme in anephric humans. J Clin Endocr. 1968; 28: 221–230
  • McKenzie J.K., Montgomerie J.Z. Renin-like activity in the plasma of anephric men. Nature 1969; 223: 1156
  • Medina A., Bell P.R.F., Briggs J.D., et al. Changes of blood pressure, renin, and angiotensin after bilateral nephrectomy in patients with chronic renal failure. Br Med J. 1972; 4: 694–696
  • Yu R., Anderton J., Skinner S.L., Best J.B. Renin in anephric man: Case report with physiologic studies. Am J Med. 1972; 52: 707–711
  • Weidmann P., Horton R., Maxwell M.H., Franklin S.S., Fichman M. Dynamic studies of aldosterone in anephric man. Kidney Int. 1973; 4: 289–298
  • Williams G.H., Bailey G.L., Hampers C.L., et al. Studies on the metabolism of aldosterone in chronic renal failure and anephric man. Kidney Int. 1973; 4: 280–288
  • Deheneffe J., Cuesta V., Briggs J.D., et al. Response of aldosterone and blood pressure to angiotensin II infusion in anephric man: Effect of sodium deprivation. Circ Res. 1976; 39: 183–190
  • Sealey J.E., White R.P., Laragh J.H., Rubin A.L. Plasma prorenin and renin in anephric patients. Circ Res. 1977; 41(suppl 2)II-17–II-21
  • Sealey J.E., Moon C., Laragh J.H., Atlas S.A. Plasma prorenin in normal, hypertensive, and anephric subjects and its effect on renin measurements. Circ Res. 1977; 40(Suppl I)I-41–I-45
  • Weinberger M.H., Wade M.B., Aoi W., et al. An extrarenal source of “renin-like” activity in anephric man. Circ Res. 1977; 40(suppl 1)I-1–I-4
  • Konrads A., Hummerich W., Wambach G., Böttcher W., Meurer K.A. Extrarenal prorenin and renin in anephric patients. Klin Wochenschr. 1980; 58: 233–236
  • Leslie B.R., Case D.B., Sullivan J.F., Vaughan E.D., Jr. Absence of blood-pressure lowering effect of captopril in anephric patients. Br Med J. 1980; 280: 1067–1068
  • Man in't Veld A.J., Schicht I.M., Derkx F.H.M., deBruyn J.H.B., Schalekamp M. A.D.H. Effects of an angiotensin-converting enzyme inhibitor (captopril) on blood pressure in anephric subjects. Br Med J. 1980; 280: 288–290
  • Konrads A., Hummerich W., Vlaho M., Meurer K.A. Effects of furosemide and orthostasis on active and inactive renin in normal and anephric man. Eur J Clin Invest. 1981; 11: 105–109
  • Taylor G.M., Carmichael D.J.S., Peart W.S. Active and inactive renin in anephric man: A comparison of molecular weight studies with normal human plasma and the effect of a specific monoclonal anti-renin antibody. J Hypertens. 1986; 4: 703–712
  • Wenting G.J., Blankestijn P.J., Poldermans D., et al. Blood pressure response of nephrectomized subjects and patients with essential hypertension to ramipril: Indirect evidence that inhibition of tissue angiotensin converting enzyme is important. Am J Cardiol. 1987; 59: 92D–97D
  • Derkx F.H.M., Schalekamp M. A.D.H. Human prorenin: Pathophysiology and clinical implications. Clin and Exper Hyper-Theory and Practice 1988; A10(6)1213–1225
  • Blankenstijn P.J., Derkx F.H.M., Van Geelen J.A., Dejong F.H., Schalekamp M. A.D.H. Increase in plasma prorenin during the menstrual cycle of a bilaterally nephrectomized woman. Br J Obstet Gynaecol. 1990; 97: 1038–1042
  • Mizuno K., Higashimori K., Stone W.J., Shimamoto K., Fukuchi S., Inagami T. Re-evaluation of the plasma renin-angiotensin system in anephric patients. Clin and Exper Hyper—Theory and Practice 1990; A12: 1135–1157
  • Campbell D.J., Kladis A., Skinner S.L., Whitworth J.A. Characterization of angiotensin peptides in plasma of anephric man. J Hypertens. 1991; 9: 265–274
  • Wilkes B.M., Mento P.F., Pearl A.R., et al. Plasma angiotensins in anephric humans: Evidence for an extrarenal angiotensin system. J Cardiovasc Pharmacol. 1991; 17: 419–423
  • Sealey J.E. Plasma renin activity and plasma prorenin assays. Clin Chem 1991; 37/10(B)1811–1819
  • Nicar M.J. Specimen processing and renin activity in plasma. Clin Chem 1991; 38: 598
  • Lenz T., Sealey J.E., Lappe R.W., et al. Infusion of recombinant human prorenin into rhesus monkeys: Effects on hemodynamics, renin-angiotensin-aldosterone axis and plasma testosterone. Am J Hypertens. 1990; 3: 257–261
  • Kim S., Hosoi M., Ikemoto F., Murakami K., Ishizuka Y., Yamamoto K. Conversion to renin of exogenously administered recombinant human prorenin in liver and kidney of monkeys. Am J Physiol. 1990; 258: E451–E458, Endocrinol Metab 21
  • Lenz T., Sealey J.E., Maack T., et al. Half-life, hemodynamic, renal, and hormonal effects of prorenin in cynomolgus monkeys. Am J Phys. 1991; 260: R804–R810, Regulatory Integrative Comp Physiol 29
  • Eggena P., Barrett J.D., Wiedeman C.E., Golub M.S., Thananopavarn C., Villarreal H., Sambhi M.P. Isoelectric heterogeneity of active and inactive renin-like enzymes in human plasma and tissues. Heterogeneity of Renin and Renin-Substrate, Sambhi. Elsevier, North Holland 1981; 215–225
  • Sealey J.E., Rubattu S. Prorenin and renin as separate mediators of tissue and circulating systems. Am J Hypertens. 1989; 2: 358–366

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.