Advanced search
Publication Cover
Clinical and Experimental Hypertension Volume 15, 1993 - Issue 3
Submit an article Journal homepage
14
Views
15
CrossRef citations to date
0
Altmetric
Original Article

Beta-Alanine and Taurine Microinjected into the Rat Caudal Ventrolateral Medulla Increase Blood Pressure

T. Kubo Department of Pharmacology, Showa College of Pharmaceutical Sciences, Machida, Tokyo, 194, Japan
,
M. Amano Department of Pharmacology, Showa College of Pharmaceutical Sciences, Machida, Tokyo, 194, Japan
,
T. Ishizuka Department of Pharmacology, Showa College of Pharmaceutical Sciences, Machida, Tokyo, 194, Japan
&
S. Ozaki Department of Pharmacology, Showa College of Pharmaceutical Sciences, Machida, Tokyo, 194, Japan
Pages 585-597 | Received 07 Jan 1992, Accepted 04 Jan 1993, Published online: 03 Jul 2009

References

  • Blessing W. W., West M. J., Chalmers J. Hypertension, bradycardia, and pulmonary edema in the conscious rabbit after brainstem lesions coinciding with the Al group of catecholamine neurons. Circulation Res. 1981; 49: 949–958
  • Willette R. N., Barcas P. P., Krieger A. J., Sapru H. N. Vasopressor and depressor areas in the rat medulla. Identification by microinjection of L-glutamate. Neuropharmacology 1983; 22: 1071–1079
  • Blessing W. W., Reis D. J. Evidence that GABA and glycine-like inputs inhibit vasodepressor neurons in the caudal ventrolateral medulla of the rabbit. Neurosci Lett. 1983; 37: 57–62
  • Kihara M., Kubo T. Cardiovascular effects of GABA system activating drugs injected into the caudal ventrolateral medulla of the rat. Arch int Pharmacodyn Ther. 1988; 295: 67–79
  • Willette R. N., Krieger A. J., Barcas P. P., Sapru H. N. Medullary γ-aminobutyric acid (GABA) receptors and the regulation of blood pressure in the rat. J Pharmacol Exp Ther. 1983; 226: 893–899
  • Kubo T., Kihara M., Misu Y. Altered amino acid levels in brainstem regions of spontaneously hypertensive rats. Clin Exper Hyper. 1989; A11: 233–241
  • Kubo T., Kihara M., Misu Y. Genetically altered brain amino acid metabolism in spontaneously hypertensive rats: a study by using young spontaneously hypertensive rats and renal hypertensive rats. Clin Exper Hyper. 1990; A12: 1191–1201
  • Kubo T., Amano H. Vasopressin-induced pressor responses in rats to bilateral electrolytic lesioning of the caudal portion of the nucleus tractus solitarii. Brain Res. 1986; 363: 183–187
  • Kleinman L. I., Radford E. P. Ventilation standards for small mammals. J Appl Physiol. 1964; 19: 360–362
  • Kubo T., Kihara M. N-Methyl-D-aspartate receptors mediate tonic vasodepressor control in the caudal ventrolateral medulla of the rat. Brain Res. 1988; 451: 366–370
  • Philippu A., Przuntek H., Roensberg W. Superfusion of the hypothalamus with gamma-aminobutyric acid. Effects on release of noradrenaline and blood pressure. Naunyn-Schmiedeberg's Arch Pharmacol. 1973; 276: 103–118
  • Huxtable R. J., Sebring L. A. Towards a unifying theory for the actions of taurine. Trends Pharmacol Sci. 1986; 7: 481–484
  • Curtis D. R., Hosli Johnston L., Johnston G. A.R.I.H. The hyperpolarization of spinal motoneurons by glycine and related amino acids. Exp Brain Res. 1968; 5: 235–258
  • Haas H. L., Hosli L. The depression of brainstem neurons by taurine and its interaction with strychnine and bicuculline. Brain Res. 1973; 52: 399–402
  • Sonnhof U., Krumnikl P., Grafe J., Linder M., Schindler L. Inhibitory postsynaptic actions of taurine, GABA and other amino acids on motoneurons of the isolated spinal cord. Brain Res. 1975; 100: 327–341
  • Bousquet P., Feldman J., Bloch R., Schwartz J. Central cardiovascular effects of taurine: comparison with homotaurine and muscimol. J Pharmacol Exp Ther. 1981; 219: 213–218
  • Martin G. E., Bendesky R. J., Williams M. Further evidence for a selective antagonism of taurine by 6-aminomethyl-4H-1,2,4-benzothiadiazine-1,1-dioxide. Brain Res. 1981; 229: 530–535
  • Fujita T., Sato Y., Ando K. Changes in cardiac and hypothalamic noradrenergic activity with taurine in DOCA-salt rats. Am J Physiol. 1986; 251: H926–H933
  • Kuriyama K., Ida S., Ohkuma S. Alteration of cerebral taurine biosynthesis in spontaneously hypertensive rats. J Neurochem. 1984; 42: 1600–1606
  • Nara Yamori Y. Y., Lovenberg W. Effect of taurine on blood pressure in spontaneously hypertensive rats. Biochem Pharmacol. 1978; 27: 2689–2692
  • Gatti P. J., Souza J. D., DaNamath I. J., Silva A. M.T., Holtman J. R., Jr., Gillis R. Comparative cardiorespiratory effects produced by taurine and glycine applied to the ventral surface of the medulla. J Pharmacol Exp Ther. 1985; 235: 820–828
  • Korpi E. R., Kontro P., Nieminen K., Marnela K.-M., Oja S. S. Spontaneous and depolarization-induced efflux of hypotaurine from mouse cerebral cortex slices: comparisons with taurine and GABA. Life Sci. 1981; 29: 811–816
  • Smith L. F.P., Pycock C. J. Potassium-stimulated release of radiolabelled taurine and glycine from the isolated rat retina. J. Neurochem. 1982; 39: 653–658
  • Kontro P., Korpi E. R., Oja S. S. Taurine interacts with GABAA and GABAB receptors in the brain. Taurine: Functional Neurochemistry, Physiology, and Cardiology, H. Pasantes-Morales, D. L. Martin, W. Shain, R. Martin del Rio. Wiley-Liss, New York 1990; 83–94

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.