Advanced search
Publication Cover
Clinical and Experimental Hypertension Volume 18, 1996 - Issue 2
Submit an article Journal homepage
32
Views
35
CrossRef citations to date
0
Altmetric
Original Article

Vascular Reactivity to Phenylephrine and Angiotensin II in Hypertensive Rats Associated with Insulin Resistance

Shridhar N. Iyer Department of Pharmacodynamics College of Pharmacy, University of Florida Gainesville, FL, 32610
&
Michael J. Katovich Department of Pharmacodynamics College of Pharmacy, University of Florida Gainesville, FL, 32610
Pages 227-242 | Received 06 Jun 1995, Accepted 11 Oct 1995, Published online: 03 Jul 2009

References

  • Hwang I. S., Ho H., Hoffman B. B., Reaven G. M. Fructose-induced insulin resistance and hypertension in rats. Hypertension 1987; 10: 512–516
  • Reaven G. M., Ho H., Hoffman B. B. Attenuation of fructose-induced hypertension in rats by exercise training. Hypertension 1988; 12: 129–132
  • Bhanot S., McNeill J., Bryer-Ash M. Vanadyl sulfate prevents fructose-induced hyperinsulinemia and hypertension in rats. Hypertension 1994; 23: 308–312
  • Dai S., Todd M. E., Lee S., McNeill J. H. Fructose feeding induces cardiovascular and metabolic changes in nondiabetic and diabetic rats. Can J Physiol Pharmacol. 1994; 72: 771–781
  • Reaven G. M., Hoffman B. B. Somatostatin inhibits fructose-induced hypertension. Hypertension 1989; 14: 117–120
  • Kaufman L. N., Hui-Yun L., Peterson M. M., Gilardy A. K. Adrenal medulla as a mediator of diet-induced hypertension. Am J Physiol. 1993; 265: R1–R6
  • Iimura O., Shimamoto K., Matsuda K., Masuda A., Takizawa H., Higashiura K., Miyazaki Y., Hirata A., Ura N., Nakagawa M. Effects of angiotensin receptor antagonist and angiotensin converting enzyme inhibitor on insulin sensitivity in Fructose-fed hypertensive rats and essential hypertensives Am J. Hypertens. 1995; 8: 353–357
  • Iyer S. N., Katovich M. J. Effect of chronic Losartan Potassium treatment on Fructose-induced hypertension. Life Sci. 1994; 55: PL 139–PL 144
  • Iyer S. N., Raizada M. K., Katovich M. J. Changes in Angiotensin AT1 receptor density during hypertension in Fructose-fed rats. Recent advances in angiotensin receptors. Plenum Press Co., New York 1995, (in press).
  • Soltis E. E., Jewell A. L., Dwoskin L. P., Cassis L. A. Acute and Chronic effects of Losartan (DUP 753) on blood pressure and vascular reactivity in normotensive rats Clin. and Exper. Hypertension 1993; 15: 171–184
  • Brands M. W., Garrity C. A., Holman M. G., Keen H. L., Alonso-Galicia M., Hall J. E. High-fructose feeding does not raise 24 hour mean blood pressure in rats. Am J Hypertens 1994; 7: 104–109
  • Bell R. S., Lewis J., Ryan E. A., Finegood D. J. Effects of fructose feeding on insulin and blood pressure level. FASEB J. 1995; 9: A152
  • Preuss M. B., Preuss H. G. The effects of sucrose and sodium on blood pressures in various substrains of Wistar rats. Lab Invest. 1980; 43: 101–107
  • Kobayashi R., Nagano M., Nakamura P., Hiyaki J., Fujioka Y., Ikegami H., Mikanni H., Kawaguchi N, Onishi S., Ogihara T. Role of Angiotensin II in high fructose-induced left ventricular hypertrophy in rats. Hypertension 1993; 21: 1051–1055
  • Smith C. D., Pearlmutter F., Szkrybalo M., Katovich M. J. Changes in vascular vasopressin receptors and responsivenessin DOCA-NaCl-treated rats Clin. Exper. Hypertension 1985; A10: 629–648
  • Schiffrin E. L., Thome F. S., Genest J. Vascular angiotensin II receptors in renal and DOCA-Salt hypertensive rats. Hypertension 1983; 5(Suppl V)V-16–V-21
  • Schiffrin E. L., Franks D. J., Gutkowska J. Effects of aldosterone on vascular angiotensin II receptors in the rat. Can J Physiol Pharmacol. 1985; 64: 1522–1527
  • Douglas J. G., Brown G. P. Effect of prlonged low dose infusion of Angiotensin II and aldosterone on rat smooth muscle and adrenal angiotensin II receptors. Endocrinology 1981; 111: 988–999
  • Trovati M., Massucco P., Anfossi G., Cavalot F., Mularoni E., Mathello L., Rocca G., Emanuelli G. Insulin influences the renin-angiotensin-aldosterone system in humans. Metabolism 1989; 38(6)501–503
  • Henrion D., Laher I., Laporte R., Bevan J. A. Angiotensin II amplifies arterial contractile response to norepinephrine without increasins Ca2+ influx: Role of Protein Kinase C. J Pharmacol Exp Ther. 1992; 261: 835–842
  • Gaboury C. L., Simonson D. C., Seely E. W., Hollenberg N. K., Williams G. H. Relation of pressor responsiveness to Angiotensin II and insulin resistance in hypertension. J Clin Invest. 1994; 94: 2295–2300
  • Baron A. D., Brechtel G., Johnson A., Fineberg N., Henry D. P., Steinburg H. O. Interactions between insulin and norepinephrine on blood pressure and insulin sensitivity. J Clin Invest. 1994; 93: 2453–2462
  • Gans R. O.B., Bilo H. J.G., Maarschalkerweer W. W.A.V., Heine R. J., Nauta J. J.P., Donker A. J.M. Exogenous insulin augments in healthy volunteers the cardiovascular reactivity to Noradrenaline but not to Angiotensin II. J Clin Invest 1991; 88: 512–518
  • Baron A. D., Brechtel G. Insulin differentially regulates systemic and skeletal muscle vascular resistance. Am J Physiol. 1993; 265: E61–E67

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.