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Clinical and Experimental Hypertension Volume 18, 1996 - Issue 2
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Original Article

Does Combined Therapy of Ca-channel Blocker and Angiotensin Converting Enzyme Inhibitor Exceed Monotherapy in Renal Protection Against Hypertensive Injury in Rats?

Yoshihiko Kanno Department of Internal Medicinc, School of Medicine, Keio University, Tokyo
,
Hirokazu Okada Department of Internal Medicinc, School of Medicine, Keio University, Tokyo
,
Hiromichi Suzuki Department of Internal Medicinc, School of Medicine, Keio University, Tokyo
,
Hideki Ikenaga Department of Internal Medicinc, School of Medicine, Keio University, Tokyo
,
Naohito Ishii Department of Internal Medicinc, School of Medicine, Keio University, Tokyo; Department of Clinical Chemistry, School of Hygienic Sciences, Kitasato University, Kanagawa, Japan
,
Hajime Itoh Department of Internal Medicinc, School of Medicine, Keio University, Tokyo; Department of Clinical Chemistry, School of Hygienic Sciences, Kitasato University, Kanagawa, Japan
&
Takao Saruta Department of Internal Medicinc, School of Medicine, Keio University, Tokyo
 show all
Pages 243-256 | Received 05 Apr 1995, Accepted 05 Oct 1995, Published online: 03 Jul 2009

References

  • Weir M R. Hypertensive nephropathy: Is a more physiologic approach to blood pressure control an important concern for the preservation of renal function?. Am J Med 1992; 93(suppl 2A)27S–37S
  • 1992 Joint National Committee: The Fifth report of the Joint National Committee on Detection, evaluation, and treatment of high blood pressure. Arch Int Med 1993; 153: 154–183
  • Stornello M, Valvo E V, Scapellato L. Hemodynamic, renal, and humoral effects of the calcium entry blocker nicardipine and converting enzyme inhibitor captoril in hypertensive type II diabetic patients with nephrology. J Cardiovasc Pharmacol 1989; 14: 851–855
  • Wenzel U, Helmchen U, Schoeppe W, Schwietzer G. Combination treatment of enalapril with nitrendipine or in rats with renovascular hypertension. Hypertension 1994; 23: 114–122
  • Dworkin L D, Feiner H D, Parker M, Tolbert E. Effects of nifedipine and enalapril on glomerular structure and function in unincphrectomized SHR. Kidney Int 1991; 39: 1112–1117
  • Burges R A, Gardiner D G, Carter A J, McKay F F. Long term natriuretic and antihypertensive activity in spontaneous hypertensive rats with developing and established hypertension Ann. N.Y. Acad. Sci. 1988; 522: 516–8
  • Terzi F, Beaufils H, Laouari D, Burtin M, Kleinknecht C. Renal effect of anti-hypertensive drugs depends on sodium diet in the excision remnant kidney model. Kidney Int 1992; 42: 354–363
  • Pfeffer J M, Pfeffer M A, Frohlich E D. Validity of an indirect tail-cuff method for determining systolic arterial pressure in unanesthctized normotensive and spontaneously hypertensive rat J. Lab. Clin. Med. 1971; 78: 957–962
  • Peterson G L. A simplification of the protein assay method of Lowry Which is more generally applicable. Anal. Biochem. 1977; 83: 346–356
  • Ikenaga H, Suzuki H, Ishii N, Itoh H, Saruta T. Role of NO on pressure-natriuresis in Wistar-Kyoto and spontaneously hypertensive rats. Kidney Int 1993; 43: 205–211
  • Okada H, Suzuki H, Konishi K, Sakaguchi H, Saruta T. Histological alterations in renal specimens as indicators of prognosis of IgA nephropathy. Clin Nephrol 1992; 37: 235–238
  • Wallenstein S, Zucker C L, Fleiss J. Some statistical methods useful on circulation research. Circ Res 1980; 47: 1–9
  • Guazzi M D, De-Cesare N, Galli C, Salvioni A, Tramontana C, Tamborini G, Bartorelli A. Calcium- channel blockade with nifedipine and angiotensin converting-enzyme inhibition with captopril in the therapy of patients with severe primary hypertension. Circulation 1984; 70: 279–284
  • Anderson A, Morgan T. Interaction of enalapril with sodium restriction, diuretics, and slow-channel-calcium-blocking drugs Nephron 1990; 55(suppl. 1)70–72
  • Glorioso N, Manunta P, Troffa C, Pazzola A, Soro A, Pala F, Meris M G, Madeddu P, Tonolo G. Effects of nitrendipine on blood pressure, renin-angiotensin system, and kidney function in essential hypertension. J Cardiovasc Pharmacol 1988; 12(suppl 4)S142–S145
  • Kureya P, Beevers D G. The mechanisms of hypertension and the role of ACE inhibitors. J Hum Hypertens 1991; 5: 3–8
  • Reams G P, Lau A, Hamony A, Bauer H. Amlodipine therapy corrects renal abnormalities encountered in hypertensive state. Am J Kidney Dis 1987; 10: 446–451
  • Loutzenhiser R D, Epstein M, Fischetti F, Horton C. Effects of amlodipine on renal hemodynamics. Am J Cardiol 1989; 64: 1221–1281
  • Jackson B, Johnston C I. The contribution of systemic hypertension to progression of chronic renal failure in the rat remmnant kidney: effect of treatment with an angiotensin converting enzyme inhibitor or a calcium inhibitor. J Hypertens 1988; 6: 495–501
  • Brunner F P, Thiel G, Hermle M, Bock A, Mihatsch M J. Long-term enalapril and verapamil in rats with reduced renal mass. Kidney Int 1989; 36: 969–977
  • Ulm E H, Hichens M, Gomez H J, Till A E, Hand E, Vassil T C, Biollaz J, Brunner H R, Schelling J L. Enalapril malcate and a lysine analogue (MK-521) disposition in man. Br J Clin Pharmac 1982; 14: 357–362
  • Nurges R A, Dodd M G. Amlodipine. Cardiovascular Drug Reviews 1990; 8: 25–44
  • Marre M. Microalbuminuria and. ACE inhibition in non-hypertensive diabetics J Diabetic Complications 1990; 4: 84–5
  • Brunner H R, Menard J, Waeber B, Burnicr M, Biollaz J, Nussberger J, Bellet M. Treating the individual hypertensive patient:considerations on dose, sequential monotherapy and drug combinations. J Hypertens 1990; 8: 3–11
  • Frohlich E D, Chien Y, Sesoko S, Pegram B L. Relationship between dietary-sodium intake, hemodynamics, and cardiac mass in SHR and WKY rats. Am J Physiol 1993; 264: R30–R34

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