5
Views
5
CrossRef citations to date
0
Altmetric
Original Article

Acetylcholine Induces Contraction in Vertebral Arteries from Treated Hypertensive Patients

, , &
Pages 87-99 | Received 02 Mar 1994, Accepted 24 Jul 1995, Published online: 03 Jul 2009

References

  • Dzau V. J., Gibbons G. H. Cell biology of vascular hypertrophy in systemic hypertension. Am J Cardiol 1988; 62: 30G–35G
  • Owens G. K., Schwartz S. M., McCanna M. Evaluation of medial hypertrophy in resistance vessels of spontaneously hypertensive rats. Hypertension 1988; 11: 198–207
  • Van de Voorde J., Leusen I. Endothelium-dependent and independent relaxation of aortic rings from hypertensive rats. Am J Physiol 1986; 250(Heart Circ Physiolo 19)H711–H717
  • Sim M. K., Chua M. E. Altered responsiveness of the aorta of hypertensive rats to histamine and acetylcholine. Japan J Pharmacol 1985; 39: 551–553
  • Osugi S., Shimamura K., Sunano S. Decreased modulation by endothelium of noradrenaline-induced contractions in aorta from stroke-prone spontaneously hypertensive rats. Arch Int Pharmacodyn 1990; 305: 86–99
  • Dzau V. J., Gibbons G. H. Autocrine-paracrine mechanisms of vascular myocytes in systemic hypertension. Am J Cardiol 1987; 60: 99I–103I
  • Papadopoulos S. M., Gilbert L. L., Webb R. C., D'Amato C. J. Characterization of contractile responses to endothelin in human cerebral arteries. Neurosurgery 1990; 810–815
  • Bruner C. A., Thompson L. P., Webb R. C. Vascular properties in hypertension: structural. functional and cellular changes. Blood Vessel Wall and Thrombosis, R Machovich. CRC Press Inc., Boca Raton, Florida 1988; 25–49
  • Charpie J. R., Schreur K. D., Papadopoulos S. M., Webb R. C. Endothelium dependency of contractile activity differs in infant and adult vertebral arteries. J Clin Invest 1994; 93: 1339–1343
  • Lüscher T. F., Raij L., Vanhoutte P. M. Endothelium-dependent vascular responses in normotensive and hypertensive Dahl rats. Hypertension 1987; 9: 157–163
  • Konishi M., Su C. Role of endothelium in dilator responses of spontaneously hypertensive rat arteries. Hypertension 1983; 5: 881–886
  • Winquist R. J., Bunting P. B., Baskin E. P., Wallace A. A. Decreased endothlium-dependent relaxation in New Zealand genetic hypertensive rats. J Hypertension 1984; 2: 541–546
  • Linder L., Kiowski W., Buhler F. R., Luscher T. F. Indirect evidence for the release of endothelium-derived relaxing factor in the human forearm circulation in vivo: blunted response in essential hypertension. Circulation 1990; 81: 1762–1767
  • Panza J. A., Quyyumi A. A., Brush J. E., Jr., Epstein S. E. Abnormal endothelium dependent vascular relaxation in patients with essential hypertension. N Engl J Med 1990; 323: 22–27
  • Taddei S., Virdis A., Mattei P., Salvetti A. Vasodilation to acetylcholine in primary and secondary forms of human hypertension. Hypertension 1993; 21: 929–933
  • Lüscher T. F., Vanhoutte P. M. Endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat. Hypertension 1986; 8: 344–348
  • Heagerty A. M., Bund S. J., Aalkjaer C. Effects of drug treatment on resistance arteriole morphology in essential hypertension: direct evidence for structural remodelling of resistance vessels. Lancet 1988; 2: 1209–1212
  • Aalkjaer C., Eiskjaer H., Mulvany M. J., Jespersen B., Kjaer K T, Sorensen S. S., Pedersen E. B. Abnormal structure and function of isolated subcutaneous resistance vessels from essential hypertensive patients despite antihypertensive treatment. J Hypertens 1989; 7: 305–310
  • Lee R. M.K.W., Smeda J. S. Primary versus secondary structural changes of the blood vessels in hypertension. Can J Physiol Pharmacol 1985; 63: 392–401
  • Hamilton T. C. Influence of anti-hypertensive drug treatment on vascular reactivity in spontaneously hypertensive rats. Br J Pharmacol 1975; 54: 429–436
  • Pang C. C.Y., Sutter M. C. Effect of chronic treatment of spontaneously hypertensive rats with D600. Hypertension 1981; 3: 657–663
  • Warshaw D. M., Root D. T., Halpern W. Effects of antihypertensive drug therapy on the morphology and mechanics of resistance arteries from spontaneously hypertensive rats. Blood Vessels 1980; 17: 257–270
  • Watts S. W., Traub O., Lamb F. S., Myers J. H., Webb R. C. Effect of ramipril on α-adrenoceptor-mediated oscillatory contractions in tail artery of hypertensive rats. Euro J Pharmacol 1993; 242: 245–253
  • Watts S. W., Traub O., Webb R. C. Effects of ramipril on contractile oscillations in arteries from genetically hypertensive rats. Clin Exper Hypertension 1994; 16(6)881–898
  • Traub O, Webb R. C. Angiotensin-converting enzyme inhibition during development alters calcium regulatioin in adult hypertensive rats. J Pharmacol Exper Therap 1993; 267(3)1503–1508
  • Dahlof B., Herlitz H., Aurell M., Hansson L. Reversal of cardiovascular structural changes when treating essential hypertension: the importance of the renin-angiotensin-aldosterone system. Am J Hypertens 1992; 5: 900–911
  • Schulman S. P., Weiss J. L., Becker L. C., et al. The effects of antihypertensive therapy on left ventricular mass in elderly patients. N Engl J Med 1990; 322: 1350–1356
  • Schiffrin E. L., Deng L. Y., Larochelle P. Effects of a beta-blocker or a ocnverting enzyme inhibitor on resistance arteries in essential hypertension. Hypertension 1994; 23: 83–91
  • Thybo N. K., Stephens N., Cooper A, Aalkjaer C., Heagerty A. M., Mulvany M. J. Effect of antihypertensive treatment on small arteries of patients with previously untreated essential hypertension. Hypertension 1995; 25(part 1)474–481
  • Barenbrock M., Spieker C., Hoeks A. P.G., Zidek W., Rahn K. H. Effect of lisinopril and metoprolol on arterial distensibility. Hypertension 1994; 23(suppl I)I161–I163
  • Shimamoto H, Shimamoto Y. Lisinopril improves aortic compliance and renal flow: comparison with nifiedipine. Hypertension 1995; 25: 327–334

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.