Augmented nitric oxide generation in neutrophils: Oxidative and pro-inflammatory implications in hypertension

References

• Grundy SM. Inflammation, hypertension, and the metabolic syndrome. JAMA 2003;290:3000–3002.
   PubMed Web of Science ®Google Scholar
• Dhalla NS, Temsah RM, Netticadan T. Role of oxidative stress in cardiovascular diseases. J Hypertens 2000;18:655–673.
   PubMed Web of Science ®Google Scholar
• Ferroni P, Basili S, Paoletti V, Davi G. Endothelial dysfunction and oxidative stress in arterial hypertension. Nutr Metab Cardiovasc Dis 2006;16:222–233.
   PubMed Web of Science ®Google Scholar
• Li JJ, Chen JL. Inflammation may be a bridge connecting hypertension and atherosclerosis. Med Hypotheses 2005;64:925–929.
   PubMed Web of Science ®Google Scholar
• Olzinski AR, McCafferty TA, Zhao SQ, Behm DJ, Eybye ME, Maniscalco K, Bentley R, Frazier KS, Milliner CM, Mirabile RC, Coatney RW, Willette RN. Hypertensive target organ damage is attenuated by a p38 MAPK inhibitor:Role of systemic blood pressure and endothelial protection. Cardiovasc Res 2005;66:170–178.
   PubMed Web of Science ®Google Scholar
• Paffen E, deMaat MPM. C-reactive protein in atherosclerosis: a causal factor?. Cardiovasc Res 2006;71:30–39.
   PubMed Web of Science ®Google Scholar
• Grunfeld S, Hamilton CA, Mesaros S, McClain SW, Dominiczak AF, Bohr DF, Malinski T. Role of superoxide in the depressed nitric oxide production by the endothelium of genetically hypertensive rats. Hypertension 1995;26:854–857.
   PubMed Web of Science ®Google Scholar
• Hegde LG, Srivastava P, Kumari R, Dikshit M. Alterations in the vasoreactivity of hypertensive rat aortic rings: role of nitric oxide and superoxide radicals. Clin Exp Hypertension 1998;20:885–901.
   PubMed Web of Science ®Google Scholar
• Kerr S, Brosnan MJ, McIntyre M, Reid JL, Dominiczak AF, Hamilton CA. Superoxide anion production is increased in a model of genetic hypertension: role of the endothelium. Hypertension 1999;33:1353–1358.
   PubMed Web of Science ®Google Scholar
• Bouloumie A, Bauersachs J, Ling W, Scholkens BA, Wiemer G, Fleming I, Busse R. Endothelial dysfunction coincides with an enhanced nitric oxide synthase expression and superoxide anion production. Hypertension 1997;30:934–941.
   PubMed Web of Science ®Google Scholar
• Ulker S, McMaster D, McKeown PP, Bayraktutan U. Impaired activities of antioxidant enzymes elicit endothelial dysfunction in spontaneous hypertensive rats despite enhanced vascular nitric oxide generation. Cardiovasc Res 2003;59:488–500.
   PubMed Web of Science ®Google Scholar
• Salvemini D, de Nucci G, Gryglewski RJ, Vane JR. Human neutrophils and mononuclear cells inhibit platelet aggregation by releasing a nitric oxide-like factor. Proc Natl Acad Sci USA 1989;86:6328–6332.
   PubMed Web of Science ®Google Scholar
• Kristal B, Shurtz-Swirski R, Chezar J, Manaster J, Levy R, Shapiro G, Weissman I, Shasha SM, Sela S. Participation of peripheral polymorphonuclear leukocytes in the oxidative stress and inflammation in patients with essential hypertension. Am J Hypertens 1998;11:921–928.
   PubMed Web of Science ®Google Scholar
• Morton J, Coles B, Wright K, Gallimore A, Morrow JD, Terry ES, Anning PB, Morgan BP, Dioszeghy V, Kühn H, Chaitidis P, Hobbs AJ, Jones SA, O'Donnell VB. Circulating neutrophils maintain physiological blood pressure by suppressing bacteria and IFNgamma-dependent iNOS expression in the vasculature of healthy mice. Blood 2008;111:5187–5194.
   PubMed Web of Science ®Google Scholar
• Jackson MH, Collier A. Neutrophil count and activation in vascular disease. Scot Med J 1992;37:41–43.
   PubMedGoogle Scholar
• Nicolini FA, Mehta JL. Inhibitory effect of unstimulated neutrophils on platelet aggregation by release of a factor similar to endothelium-derived relaxing factor (EDRF). Biochem Pharmacol 1990;40:2265–2269.
   PubMed Web of Science ®Google Scholar
• Kosonen O, Kankaanranta H, Uotila J, Moilanen E. Inhibition by nitric oxide-releasing compounds of E-selectin expression in and neutrophil adhesion to human endothelial cells. Eur J Pharmacol 2000;394:149–156.
   PubMedGoogle Scholar
• Sethi S, Dikshit M. Modulation of polymorphonuclear leukocytes function by nitric oxide. Thromb Res 2000;100:223–247.
   PubMed Web of Science ®Google Scholar
• Chatterjee M, Saluja R, Kanneganti S, Chinta S, Dikshit M. Biochemical and molecular evaluation of neutrophil NOS in spontaneously hypertensive rats. Cell Mol Biol 2007;53:84–92.
   PubMed Web of Science ®Google Scholar
• Herrmann G, Hlushchuk R, Baum O, Scotti AL. Nitric oxide synthase protein levels, not the mRNA, are down-regulated in olfactory bulb interneurons of reeler mice. J Chem Neuroanat 2007;33:87–96.
   Google Scholar
• Sharma P, Barthwal MK, Dikshit M. NO synthesis and its regulation in the arachidonic-acid-stimulated rat polymorphonuclear leukocytes. Nitric Oxide 2002;7:119–126.
   PubMed Web of Science ®Google Scholar
• Pachori AS, Melo LG, Hart ML, Noiseux N, Zhang L, Morello F, Solomon SD, Stahl GL, Pratt RE, Dzau VJ. Hypoxia-regulated therapeutic gene as a preemptive treatment strategy against ischemia/reperfusion tissue injury. Proc Natl Acad Sci USA 2004;101:12282–12287.
   PubMed Web of Science ®Google Scholar
• Dejucq N, Dugast I, Ruffault A, van der Meide PH, Jegou B. Interferon-α and γ expression in the rat testis. Endocrinology 1995;136:4925–4931.
   PubMedGoogle Scholar
• van Tol EAF, Holt L, Li FL, Kong FM, Rippe R, Yamauchi M, Pucilowska J, Lund PK, Sartor RB. Bacterial cell wall polymers promote intestinal fibrosis by direct stimulation of myofibroblasts. Am J Physiol Gastrointest Liver Physiol 1999;277:G245–G255.
   PubMedGoogle Scholar
• Bredius RGM, de vries EE, Troelslral A, Alphen LV, Weening RS, Van de Winkle J, Out TA. Phagocytosis of Staphylococcus aureus and Hemophilus influenze Type B opsonized by polyclonal Human IgG1 and IgG2 antibodies. J Immunol 1993;151:1463–1472.
   PubMed Web of Science ®Google Scholar
• Graff G, Gamache DA, Brady MT, Spellman JM, Yanni JM. Improved myeloperoxidase assay for quantitation of neutrophil influx in a rat model of endotoxin-induced uveitis. J Pharmacol Toxicol Meth 1998;39:169–178.
   PubMed Web of Science ®Google Scholar
• Sela S, Shurtz-Swirski R, Farah R, Levy R, Shapiro G, Chezar J, Shasha SM, Kristal B. A link between polymorphonuclear leukocyte intracellular calcium, plasma insulin, and essential hypertension. Am J Hypertens 2002;15:1491–1502.
   Google Scholar
• Hur J, Kang MK, Park JY, Lee SY, Bae YS, Lee SH, Park YM, Kwak JY. Pro-apoptotic effect of high concentrations of histamine on human neutrophils. Int Immunopharmacol 2003;3:1491–1502.
   Google Scholar
• Kato T, Kitagawa S. Regulation of neutrophil functions by proinflammatory cytokines. Int J Hematol 2006;84:205–209.
   PubMed Web of Science ®Google Scholar
• Nathan C. Inducible nitric oxide synthase: what difference does it make?. J Clin Invest 1997;100:2417–2423.
   PubMed Web of Science ®Google Scholar
• Egan LJ, Mays DC, Huntoon CJ, Bell MP, Pike MG, Sandborn WJ, Lipsky JJ, McKean DJ. Inhibition of inter-leukin-1-stimulated NF-kappaB RelA/p65 phosphorylation by mesalamine is accompanied by decreased transcriptional activity. J Biol Chem 1999;274:26448–26453.
   PubMed Web of Science ®Google Scholar
• Lorsbach RB, Murphy W, Raval P, Snowman AM, Snyder SH, Russell SW. Expression of nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for synergy between interferon-γ and liposaccharide. J Biol Chem 1993;268:1908–1913.
   PubMed Web of Science ®Google Scholar
• Sethi S, Singh MP, Dikshit M. Nitric oxide-mediated augmentation of polymorphonuclear free radical generation after hypoxia-reoxygenation. Blood 1999;93:333–340.
   PubMed Web of Science ®Google Scholar
• Seth P, Kumari R, Dikshit M, Srimal RC. Modulation of rat peripheral polymorphonuclear leukocyte response by nitric oxide and arginine. Blood 1994;84:2741–2748.
   PubMed Web of Science ®Google Scholar
• Kim PK, Zamora R, Petrosko P, Billiar TR. The regulatory role of nitric oxide in apoptosis. Int Immunopharmacol 2001;1:1421–1441.
   PubMed Web of Science ®Google Scholar
• Sohn HY, Krotz F, Zahler S, Gloe T, Keller M, Theisen K, Schiele TM, Klauss V, Pohl U. Crucial role of local peroxynitrite formation in neutrophil-induced endothelial cell activation. Cardiovasc Res 2003;57:804–815.
   PubMed Web of Science ®Google Scholar
• Ofosu-Appiah W, Sfeir G, Smith D, Richard T. Neutrophil-mediated damage to vascular endothelium in the spontaneously hypertensive rat. Clin Immunol Immunopathol 1997;83:293–301.
   PubMedGoogle Scholar
• Cedergren J, Follin P, Forslund T, Lindmark M, Sundqvist T, Skogh T. Inducible nitric oxide synthase (NOS II) is constitutive in human neutrophils. APMIS 2003;111:963–968.
   PubMed Web of Science ®Google Scholar
• Greenberg SS, Ouyang J, Zhao X, Giles TD. Human and rat neutrophils constitutively express neural nitric oxide synthase mRNA. Nitric Oxide 1998;2:203–212.
   Google Scholar
• de Frutos, Sanchez dM, Farre J, Gomez J, Romero J, Marcos-Alberca P, Nunez A, Rico L, Lopez-Farre A. Expression of an endothelial-type nitric oxide synthase isoform in human neutrophils: modification by tumor necrosis factor-alpha and during acute myocardial infarction. J Am Coll Cardiol 2001;;37:800–807..
   Google Scholar
• Clapp BR, Hingorani AD, Kharbanda RK, Mohamed-Ali V, Stephens JW, Vallance P, MacAllister RJ. Inflammation-induced endothelial dysfunction involves reduced nitric oxide bioavailability and increased oxidant stress. Cardiovasc Res 2004;64:172–178.
   PubMed Web of Science ®Google Scholar
• Liu VWT, Huang PL. Cardiovascular roles of nitric oxide: A review of insights from nitric oxide synthase gene disrupted mice. Cardiovasc Res 2008;77:19–29.
   PubMed Web of Science ®Google Scholar
• Saini R, Patel S, Saluja R, Sahasrabuddhe AA, Singh MP, Habib S, Bajpai VK, Dikshit M. Nitric oxide synthase localization in the rat neutrophils: immunocytochemical, molecular, and biochemical studies. J Leukoc Biol 2006;79:519–528.
   PubMed Web of Science ®Google Scholar
• Hong HJ, Hsiao G, Cheng TH, Yen MH. Supplementation with tetrahydrobiopterin suppresses the development of hypertension in spontaneously hypertensive rats. Hypertension 2001;38:1044–1048.
   PubMed Web of Science ®Google Scholar
• Peluffo G, Radi R. Biochemistry of protein tyrosine nitration in cardiovascular pathology. Cardiovasc Res 2007;75:291–302.
   PubMed Web of Science ®Google Scholar
• Clempus RE, Griendling KK. Reactive oxygen species signaling in vascular smooth muscle cells. Cardiovasc Res 2006;71:216–225.
   PubMed Web of Science ®Google Scholar