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Research Article

Alrp, a survival factor that controls the apoptotic process of regenerating liver after partial hepatectomy in rats

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Pages 534-549 | Received 31 Aug 2010, Accepted 29 Dec 2010, Published online: 04 Feb 2011

References

  • Francavilla A, Hagiya M, Porter KA, Polimeno L, Ihara I, Starzl TE. Augmenter of liver regeneration: its place in the universe of hepatic growth factors. Hepatology 1994;20: 747–757.
  • Hagiya M, Francavilla A, Polimeno L, Ihara I, Sakai H, Seki T, Shimonishi M, Porter KA, Starzl TE. Cloning and sequence analysis of the rat augmenter of liver regeneration (ALR) gene: expression of biologically active recombinant ALR and demonstration of tissue distribution. Proc Natl Acad Sci USA 1994;91:8142–8146.
  • Francavilla A, Ove P, Polimeno L, Coetzee M, Makowka L, Rose J, Van Thiel DH, Starzl TE. Extraction and partial purification of a hepatic stimulatory substance in rats, mice, and dogs. Cancer Res 1987;47:5600–5605.
  • Polimeno L, Pesetti B, Giorgio F, Moretti B, Resta L, Rossi R, Annoscia E, Patella V, Notarnicola A, Mallamaci R, Francavilla A. Expression and localization of augmenter of liver regeneration in human muscle tissue. Int J Exp Pathol 2009;90:423–430.
  • Polimeno L, Lisowsky T, Francavilla A. From yeast to man–from mitochondria to liver regeneration: a new essential gene family. Ital J Gastroenterol Hepatol 1999;31:494–500.
  • Senkevich TG, White CL, Koonin EV, Moss B. A viral member of the ERV1/ALR protein family participates in a cytoplasmic pathway of disulfide bond formation. Proc Natl Acad Sci USA 2000;97:12068–12073.
  • Klebes A, Sustar A, Kechris K, Li H, Schubiger G, Kornberg TB. Regulation of cellular plasticity in Drosophila imaginal disc cells by the Polycomb group, trithorax group and lama genes. Development 2005;13:3753–3765.
  • Thasler WE, Schlott T, Thelen P, Hellerbrand C, Bataille F, Lichtenauer M, Schlitt HJ, Jauch KW, Weiss TS. Expression of augmenter of liver regeneration (ALR) in human liver cirrhosis and carcinoma. Histopathology 2005;47:57–66.
  • Di Fonzo A, Ronchi D, Lodi T, Fassone E, Tigano M, Lamperti C, Corti S, Bordoni A, Fortunato F, Nizzardo M, Napoli L, Donadoni C, Salani S, Saladino F, Moggio M, Bresolin N, Ferrero I, Comi GP. The mitochondrial disulfide relay system protein GFER is mutated in autosomal-recessive myopathy with cataract and combined respiratory-chain deficiency. Am J Hum Genet 2009;84:594–604.
  • Levitan A, Danon A, Lisowsky T. Unique features of plant mitochondrial sulphydryl oxidase. J Biol Chem 2004;279: 20002–20008.
  • Lisowsky T. ERV1 is involved in the cell-division cycle and the maintenance of mitochondrial genomes in Saccharomyces cerevisiae. Curr Gen 1994;26:15–20.
  • Lisowsky T. Removal of an intron with unique 3' branch site creates an amino-terminal protein sequence directing the scERV1 gene product to mitochondria. Yeast 1996;12:1501–1510.
  • Klissenbauer M, Winters S, Heinlein UA, Lisowsky T. Accumulation of the mitochondrial form of the sulphydryl oxidase Erv1p/Alrp during the early stages of spermatogenesis. J Exp Biol 2002;205:1979–1986.
  • Todd LR, Damin MN, Gomathinayagam R, Horn SR, Means AR, Sankar U. Growth factor erv1-like modulates Drp1 to preserve mitochondrial dynamics and function in mouse embryonic stem cells. Mol Biol Cell 2010;21:1225–1236.
  • Lisowsky T, Lee JE, Polimeno L, Francavilla A, Hofhaus G. Mammalian augmenter of liver regeneration protein is a sulfhydryl oxidase. Dig Liver Dis 2001;33:173–180.
  • Francavilla A, Starzl TE, Porter K, Foglieni CS, Michalopoulos GK, Carrieri G, Trejo J, Azzarone A, Barone M, Zeng QH. Screening for candidate hepatic growth factors by selective portal infusion after canine Eck's fistula. Hepatology 1991;14: 665–670.
  • Polimeno L, Capuano F, Marangi LC, Margiotta M, Lisowsky T, Ierardi E, Francavilla R, Francavilla A. The augmenter of liver regeneration induces mitochondrial gene expression in rat liver and enhances oxidative phosphorylation capacity of liver mitochondria. Dig Liver Dis 2000;32:510–517.
  • Polimeno L, Pesetti B, Lisowsky T, Iannone F, Resta L, Giorgio F, Mallamaci R, Buttiglione M, Santovito D, Vitiello F, Mancini ME, Francavilla A. Protective effect of augmenter of liver regeneration on hydrogen peroxide-induced apoptosis in SH-SY5Y human neuroblastoma cells. Free Radic Res 2009;43:865–875.
  • Thirunavukkarasu C, Wang LF, Harvey SA, Watkins SC, Chaillet JR, Prelich J, Starzl TE, Gandhi CR. Augmenter of liver regeneration: an important intracellular survival factor for hepatocytes. J Hepatol 2008;48:578–588.
  • Cao Y, Fu YL, Yu M, Yue PB, Ge CH, Xu WX, Zhan YQ, Li CY, Li W, Wang XH, Wang ZD, Li YH, Yang XM. Human augmenter of liver regeneration is important for hepatoma cell viability and resistance to radiation-induced oxidative stress. Free Radic Biol Med 2009;47:1057–1066.
  • Liao XH, Zhang L, Liu Q, Sun H, Peng CM, Guo H. Augmenter of liver regeneration protects kidneys from ischaemia/reperfusion injury in rats. Nephrol Dial Transplant 2010;25:2921–2929.
  • Ilowski M, Kleespies A, de Toni E, Donabauer B, Jauch KW, Hengstler JG, Thasler WE. Augmenter of liver regeneration (ALR) protects human hepatocytes against apoptosis. Biochem Biophys Res Commun 2011 Jan 7; 404 (1):148–152.
  • Polimeno L, Margiotta M, Marangi L, Lisowsky T, Azzarone A, Ierardi E, Frassanito MA, Francavilla R, Francavilla A. Molecular mechanisms of augmenter of liver regeneration as immunoregulator: its effect on interferon-gamma expression in rat liver. Dig Liver Dis 2000;32:217–225.
  • Francavilla A, Vujanovic NL, Polimeno L, Azzarone A, Iacobellis A, Deleo A, Hagiya M, Whiteside TL, Starzl TE. The in vivo effect of hepatotrophic factors augmenter of liver regeneration, hepatocyte growth factor, and insulin-like growth factor-II on liver natural killer cell functions. Hepatology 1997;25:411–415.
  • Wu CK, Dailey TA, Dailey HA, Wang BC, Rose JP. The cristal structure of Augmenter of liver regeneration: a mammalian FAD-dependent sulfhydryl oxidase. Protein Sci 2003;12: 1109–1118.
  • Gao CF, Zhou FG, Wang H, Huang YF, Ji Q, Chen J. Genetic recombinant expression and characterization of human augmenter of liver regeneration. Dig Dis Sci 2009; 54:530–537.
  • Higgins GM, Anderson RM. Experimental pathology of the liver. I. Restoration of the liver of the white rat following partial surgical removal. Arch Pathol 1931;12:186–202.
  • Ohkawa H, Ohishi N, Magi K. Assay of lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979;95:352–358.
  • Levine RL, Williams JA, Stadtman EP, Shacter E. Carbonyl assays for determination of oxidatively modified proteins. Meth Enzymol 1994;233:346–357.
  • Millonig G. Laboratory manual of biological electron microscopy. Saviolo M. Vercelli, Italy;1976 59.
  • Reynolds ES. The use of lead citrate at high pH as an electronopaque stain in electron microscopy. J Cell Biol 1963;17: 208–212.
  • Shannan B, Seifert M, Boothman DA, Tilgen W, Reichrath J. Clusterin and DNA repair: a new function in cancer for a key player in apotosis and cell cycle control. J Mol Hist 2006;37: 183–188.
  • Yang XM, Xie L, Wu ZZ, Wu CT, He FC. Increase in the level of augmenter of liver regeneration mRNA in the rat regenerating liver after partial hepatectomy. Sheng Li Xue Bao 1997;49:599–601.
  • Yang X, Xie L, Qiu Z, Wu Z, He F. Human augmenter of liver regeneration: molecular cloning, biological activity and roles in liver regeneration. Sci China C Life Sci 1997;40: 642–647.
  • Fan G, Kren BT, Steer CJ. Regulation of apoptosis-associated genes in the regenerating liver. Semin Liver Dis 1998;18: 123–140.
  • Sakamoto T, Liu Z, Murase N, Ezure T, Yokomuro S, Poli V, Demetris AJ. Mitosis and apoptosis in the liver of interleukin-6-deficient mice after partial hepatectomy. Hepatology 1999; 29:403–411.
  • Akcali KC, Dalgic A, Ucar A, Haj KB, Guvenc D. Expression of bcl-2 gene family during resection induced liver regeneration: comparison between hepatectomized and sham groups. World J Gastroenterol 2004;10:279–283.
  • Kren BT, Trembley JH, Krajewski S, Behourens TW, Reed JC, Steer CJ. Modulation of apoptosis-associated genes Bcl-2, Bcl-x and Bax during rat liver regeneration. Cell Growth Differ 1996;7:1633–1642.
  • Gandhi CR, Kuddus R, Subbotin VM, Prelich J, Murase N, Rao AS, Nalesnik MA, Watkins SC, DeLeo A, Trucco M, Starzl TE. A fresh look at augmenter of liver regeneration in rats. Hepatology 1999;29:1435–1445.
  • Xu CS, Chang CF, Yuan JY, Li WQ, Han HP, Yang KJ, Zhao LF, Li YC, Zhang HY, Rahman S, Zhang JB. Expressed genes in regenerating rat liver after partial hepatectomy. World J Gastroenterol 2005;11:2932–2940.
  • Wilson MR, Easterbrook-Smith SB. Clusterin is a secreted mammalian chaperon. Trends Biochem Sci 2000;25:95–98.
  • Bursch W, Gleeson T, Kleine L, Tenniswood M. Expression of clusterin (testosterone-repressed prostate message-2) mRNA during growth and regeneration of rat liver. Arch Toxicol 1995;69:253–258.
  • Carnovale CE, Scapini C, Alvarez ML, Favre C, Monti J, Carrillo MC. Nitric oxide release and enhancement of lipid peroxidation in regenerating rat liver. J Hepatol 2000;32: 798–804.
  • Ronco MT, de Alvarez ML, Monti J, Carrillo MC, Pisani G, Lugano MC, Carnovale CE. Modulation of balance between apoptosis and proliferation by lipid peroxidation (LPO) during rat liver regeneration. Mol Med 2002;8:808–817.
  • Kirimlioglu H, Ecevit A, Yilmaz S, Kirimlioglu V, Karabulut AB. Effect of resveratrol and melatonin on oxidative stress enzymes, regeneration, and hepatocyte ultrastructure in rats subjected to 70% partial hepatectomy. Transplant Proc 2008;40:285–289.
  • Kirimlioglu V, Karakayali H, Turkoglu S, Haberal M. Effect of resveratrol on oxidative stress enzymes in rats subjected to 70% partial hepatectomy. Transplant Proc 2008;40: 293–296.
  • Shen HM, Shi CY, Lee HP, Ong CN. Aflatoxin B1-induced lipid peroxidation in rat liver. Toxicol Appl Pharmacol 1994;127:145–150.
  • Pinkus R, Weiner LM, Daniel V. Role of oxidants and antioxidants in the induction of AP-1, NF-kappaB, and glutathione S-transferase gene expression. J Biol Chem 1996;271:13422–13429.
  • Factor VM, Laskowska D, Jensen MR, Woitach JT, Popescu NC, Thorgeirsson SS. Vitamin E reduces chromosomal damage and inhibits hepatic tumor formation in a transgenic mouse model. Proc Natl Acad Sci USA 2000;97: 2196–2201.
  • Horváth ME, González-Cabello R, Blázovics A, van der Looij M, Barta I, Müzes G, Gergely P, Fehér J. Effect of silibinin and vitamin E on restoration of cellular immune response after partial hepatectomy. J Ethnopharmacol 2001;77: 227–232.
  • Simula MP, De Re V. Hepatitis C virus-induced oxidative stress and mitochondrial dysfunction: a focus on recent advances in proteomics. Proteomics Clin Appl 2010;4:782–793.
  • Lin W, Wu G, Li S, Weinberg EM, Kumthip K, Peng LF, Mendez-Navarro J, Chen WC, Jilg N, Zhao H, Goto K, Zhang L, Brockman MA, Schuppan D, Chung RT. HIV and HCV cooperatively promote hepatic fibrogenesis via induction of reactive oxygen species and NF{kappa}B. J Biol Chem. 2011 Jan 28;286(4):2665–74.
  • Pradeep K, Raj Mohan CV, Gobianand K, Karthikeyan S. Protective effect of Cassia fistula Linn. on diethylnitrosamine induced hepatocellular damage and oxidative stress in ethanol pretreated rats. Biol Res 2010;43:113–125.
  • Sakaguchi S, Takahashi S, Sasaki T, Kumagai T, Nagata K. Progression of alcoholic or non-alcoholic steatohepatitis; common metabolic aspects of innate immune system and oxidative stress. Drug Metab Pharmacokinet 2010 [Epub ahead of print].

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