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Research Article

Protective role of D-saccharic acid-1,4-lactone in alloxan induced oxidative stress in the spleen tissue of diabetic rats is mediated by suppressing mitochondria dependent apoptotic pathway

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Pages 240-252 | Received 22 Nov 2011, Accepted 13 Dec 2011, Published online: 23 Jan 2012

References

  • Baynes JW. Role of oxidative stress in development of complication of diabetes. Diabetes 2009;40:405–412.
  • Nogichi H. Stem cells for the treatment of diabetes. Endocr J 2007;54:7–16.
  • Oberley LW. Free radicals and diabetes. Free Radiac Biol Med 1988;5:113–124.
  • Robertson RP. Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes. J Biol Chem 2004;279:42351–42354.
  • Geerlings SE, Hoepelman AI. Immune dysfunction in patients with diabetes mellitus (DM). FEMS Immunol Med Microbiol 1999;26:259–265.
  • Chang FY, Shaio MF. Decreased cell-mediated immunity in patients with noninsulin dependent diabetes mellitus. Diabetes Res Clin Pract 1999;528:137–146.
  • Thorvaldson L, Holstad M, Sandler S. Cytokine release by mueine spleen cells following multiple low dose streptozotocin-induced diabetes and treatment with a TNFa transcriptional inhibitor. Int Immunopharmacol 2003;3: 1609–1617.
  • Manna P, Ghosh J, Das J, Sil, PC. Streptozotocin induced activation of oxidative stress responsive splenic cell signaling pathways: protective role of arjunolic acid. Toxicol Appl Pharmacol 2010;244:114–129.
  • Graves DT, Kayal RA. Diabetic complications and dysregulated innate immunity. Front Biosci 2011;13:1227–1239.
  • Manna P, Sinha M, Sil PC. Protective role of arjunolic acid in response to streptozotcin-induced type-I diabetes via the mitochondrial dependent and independent pathways. Toxicology 2009;257:53–63.
  • Hanausek M, Walaszek Z, Slaga TJ. Detoxifying cancer causing agents to prevent cancer. Integr Cancer Therap 2003;2:139–144.
  • Horton D, Walaszek Z. Conformations of the D-glucarolactones and D-glucaric acid in solution. Carbohyd Res 1982;105:95–109.
  • Walaszek Z, Szemraj J, Hanausek M, Adams AK, Sherman U. D-glucaric acid content of various fruits and vegetables and cholesterol-lowering effects of dietary D-glucarate in the rat. Nutr Res 1996;16:673–681.
  • Saluk-Juszcak J, Olas B, Nowak P, Staron A, Wachowicz B. Protective effects of D-glucaro 1,4-lactone against oxidative modifications in blood platelets. Nutr Metab Cardiovas 2008;18:422–428.
  • Bhattacharya S, Chatterjee S, Manna P, Das J, Ghosh J, Gachhui R, Sil PC. 2011. Prophylactic role of D-saccharic acid-1,4-lactone in Tertiary Butyl Hydroperoxide induced cytotoxicity and cell death of murine hepatocytes via mitochondria dependent pathways. J Biochem Mol Toxicol 2011;25:341–354.
  • Bhattacharya S, Manna P, Gachhui R, Sil PC. D-saccharic acid-1,4-lactone ameliorates alloxan-induced Diabetes mellitus and oxidative stress in rats through inhibiting pancreatic beta-cells from apoptosis via mitochondrial dependent pathway. Toxicol Appl Pharmacol 2011;257: 272–283.
  • Kim JS, Ju JB, Choi CW, Kim SC. Hypoglycemic and antihyperlipidemic effect of four Korean medicinal plants in alloxan induced diabetic rats. Am J Biochem Biotechnol 2008;2:154–160.
  • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72: 248–254.
  • Nayak SS, Pattabiraman TN. A new colorimetric method for the estimation of glycosylated hemoglobin. Clin Chim Acta 1981;109:267–274.
  • Das J, Vasan V, Sil PC. Taurine exerts hypoglycemic effect in alloxan-induced diabetic rats, improves insulin-mediated glucose transport signaling pathway in heart and ameliorates cardiac oxidative stress and apoptosis. Toxicol Appl Pharmacol 2011; doi:10.1016/j.taap.2011.11.009.
  • Das J, Ghosh J, Manna P, Sinha M, Sil PC. Taurine protects rat testes against NaAsO2-induced oxidative stress and apoptosis via mitochondrial dependent and independent pathways. Toxicol Lett 2009;187:201–210.
  • Ghosh J, Das J, Manna P, Sil PC. Taurine prevents arsenic-induced cardiac oxidative stress and apoptotic damage: role of NF-κB, p38 and JNK MAPK pathway. Toxicol Appl Pharmacol 2009;240:73–87.
  • Sinha M, Manna P, Sil, PC. Protective effect of arjunolic acid against arsenic-induced oxidative stress in mouse brain. J Biochem Mol Toxicol 2008;22:15–26.
  • Sinha M, Manna P, Sil PC. Taurine, a conditionally essential amino acid, ameliorates arsenic-induced cytotoxicity in murine hepatocytes. Toxicol In Vitro 2007;21:1419–1425.
  • Sinha M, Manna P, Sil PC. Cadmium induced neurological disorders: prophylact ic role of taurine. J Appl Toxicol 2008;28:974–986.
  • Ellman GL. Tissue sulfhydryl group. Arch Biochem Biophys 1959;82:70–77.
  • Manna P, Das J, Ghosh J, Sil PC. Contribution of type 1 diabetes to rat liver dysfunction and cellular damage via activation of NOS, PARP, IκBα/NF-κB, MAPKs, and mitochondria-dependent Prophylactic role of arjunolic acid. Free Radic Biol Med 2010;48:1465–1484.
  • Rotem R, Heyfets A, Fingrut O, Blickstein D, Shaklai M, Flescher E. Jasmonates: novel anticancer agents acting directly and selectively on human cancer cell mitochondria. Cancer Res 2005;65:1984–1993.
  • Pal PB, Pal S, Das J, Sil PC. Modulation of mercury-induced mitochondria-dependent apoptosis by glycine in hepatocytes. Amino Acids 2011; DOI 10.1007/s00726-011-0869-3.
  • Kornberg A. Lactic dehydrogenase of muscle. Methods Enzymol 1955;1:441–443.
  • Manna P, Sinha M, Sil PC. Prophylactic role of arjunolic acid in response to streptozotocin mediated diabetic renal injury: activation of polyol pathway and oxidative stress responsive signaling cascades. Chem Biol Interact 2009;181: 297–308.
  • Hashemi M, Dostar Y, Rohani SR, AziziSaraji AR, Bayat M. Influence of aloxanes on the apoptosis of pancreas B-cells of rat. World J Med Sci 2009;4:70–73.
  • Kim JO, Lee GD, Kwon JH, Kim KS. Anti-diabetic effects of new herbal formula in neonatally streptozotocin-induced diabetic rats. Biol Pharm Bull 2009;32:421–426.
  • Bunn HF, Shapiro R, McManus M, Garrick L, McDonald MJ, Gallop PM, Gabbay KH. Structural heterogeneity of human hemoglobin A due to nonenzymatic glycosylation. J Biol Chem 1979;254:3892–3898.
  • Konrad P, Forsgren A, Husberg BS, Nilsson L. The immunosuppressive effect of streptozotocin-induced diabetes in rats. Res Exp Med 1986;186:455–462.
  • Mandrup-Poulsen T. 2003 Apoptotic signal transduction pathways in diabetes. Biochem Pharmacol 2003;66:1433–1440.
  • Takayanagi R, Inoguchi T, Ohnaka K. Clinical and experimental evidence for oxidative stress as an exacerbating factor of diabetes mellitus. J Clinical Biochem Nutr 2010;48:72–77.
  • Manabe E, Handa O, Naito Y, Mizushima K, Akagiri S, Adachi S, . Astaxanthin protects mesangial cells from hyperglycemia-induced oxidative signaling. J Cell Biochem 2008;103(6):1925–1937.
  • Rahman I, MacNee W. Oxidative stress and regulation of glutathione in lung inflammation. Eur Respir J 2000;16:524–554.
  • Fridovich I. Superoxide radical and superoxide dismutase. Acc Chem Res 1972;5:321–326.
  • Jones P, Suggett A. The catalase–hydrogen peroxide system. A theoretical appraisal of the mechanism of catalase action. Biochem J 1968;110:621–625.
  • Ketterer B. Detoxification reactions of glutathione and glutathione reductase. Xenobiotica 1986;16:957–975.
  • Fuliang HU, Hepburn HR, Xuan H, Chen M, Daya S, Radloff SE. Effects of propolis on blood glucose, blood lipid and free radicals in rats with diabetes mellitus. Pharmacol Res 2005;51:147–152.
  • Singh N, Anand S. Cell death by apoptosis. Indian J Exp Biol 1994;32:843–847.
  • Gross A, McDonnell JM, Korsmeyer SJ. BCL-2 family members and the mitochondria in apoptosis. Genes Dev 1999;13:1899–1911.
  • Cain K, Bratton SB, Cohen GM. The Apaf-1 apoptosome: a large caspase activating complex. Biochimie 2002;84: 203–214.
  • Slee EA, Harte MT, Kluck RM, Wolf BB, Casiano CA, Newmeyer DD, . Ordering the cytochrome c-initiated Caspase cascade: hierarchical activation of Caspases-2, -3, -6, -7, -8, and -10 in a Caspase-9- dependent manner. J Cell Biol 1999;144:281–292.

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