References
- McCord JM, Fridovich I. Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). J Biol Chem 1969;244:6049–6055.
- Toyokuni S. Role of iron in carcinogenesis: cancer as a ferrotoxic disease. Cancer Sci 2009;100:9–16
- Wang J, Pantopoulos K. Regulation of cellular iron metabolism. Biochem J 2011;434:365–381.
- Hentze MW, Kühn LC. Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress. Proc Natl Acad Sci U S A 1996;93:8175–8182.
- Mueller S, Pantopoulos K, Hübner CA, Stremmel W, Hentze MW. IRP1 activation by extracellular oxidative stress in the perfused rat liver. J Biol Chem 2001;276:23192–231926.
- Styś A, Galy B, Starzyński RR, Smuda E, Drapier JC, Lipiński P, . Iron regulatory protein 1 outcompetes iron regulatory protein 2 in regulating cellular iron homeostasis in response to nitric oxide. J Biol Chem 2011;286:22846–22854.
- Hanson ES, Leibold EA. Regulation of iron regulatory protein 1 during hypoxia and hypoxia/reoxygenation. J Biol Chem 1998;273:7588–7593.
- Pantopoulos K, Hentze MW. Activation of iron regulatory protein-1 by oxidative stress in vitro. Proc Natl Acad Sci U S A 1998;95:10559–10563.
- Pantopoulos K, Hentze MW. Rapid responses to oxidative stress mediated by iron regulatory protein. EMBO J 1995; 14:2917–2924.
- Matzuk MM, Dionne L, Guo Q, Kumar TR, Lebovitz RM. Ovarian function in superoxide dismutase 1 and 2 knockout mice. Endocrinol 1998;139:4008–4011.
- Ho YS, Gargano M, Cao J, Bronson RT, Heimler I, Hutz RJ, . Reduced fertility in female mice lacking copper-zinc superoxide dismutase. J Biol Chem 1998;273:7765–7769.
- Curry-McCoy TV, Osna NA, Nanji AA, Donohue TM Jr. Chronic ethanol consumption results in atypical liver injury in copper/zinc superoxide dismutase deficient mice. Alcohol Clin Exp Res 2010;34:251–261.
- Elchuri S, Oberley TD, Qi W, Eisenstein RS, Jackson Roberts L, Van Remmen H, . CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life. Oncogene 2005;24:367–380.
- Keithley EM, Canto C, Zheng QY, Wang X, Fischel-Ghodsian N, Johnson KR, . Cu/Zn superoxide dismutase and age-related hearing loss. Hear Res 2005;209:76–85.
- Uchiyama S, Shimizu T, Shirasawa T. CuZn-SOD deficiency causes ApoB degradation and induces hepatic lipid accumulation by impaired lipoprotein secretion in mice. J Biol Chem 2006;281:31713–31719.
- Yamanobe T, Okada F, Iuchi Y, Onuma K, Tomita Y, Fujii J, . Deterioration of ischemia/reperfusion-induced acute renal failure in SOD1-deficient mice. Free Radic Res 2007; 41:200–207.
- Iuchi Y, Okada F, Onuma K, Onoda T, Asao H, Kobayashi M, . Elevated oxidative stress in erythrocytes due to a SOD1 deficiency causes anaemia and triggers autoantibody production. Biochem J 2007;402:219–227.
- Sentman ML, Granström M, Jakobson H, Reaume A, Basu S, Marklund SL, . Phenotypes of mice lacking extracellular superoxide dismutase and copper- and zinc- containing superoxide dismutase. J Biol Chem 2006;281: 6904–6909.
- Starzynski RR, Lipinski P, Drapier JC, Diet A, Smuda E, Bartlomiejczyk T, . Down-regulation of iron regulatory protein 1 activities and expression in superoxide dismutase 1 knock-out mice is not associated with alterations in iron metabolism. J Biol Chem 2005;280:4207–4212.
- Starzyński RR, Canonne-Hergaux F, Willemetz A, Gralak MA, Woliński J, Styś A, . Haemolytic anaemia and alterations in hepatic iron metabolism in aged mice lacking Cu,Zn-superoxide dismutase. Biochem J 2009;420:383–390.
- Yoshihara D, Fujiwara N, Ookawara T, Kato S, Sakiyama H, Yokoe S, . Protective role of glutathione S-transferase A4 induced in copper/zinc-superoxide dismutase knockout mice. Free Radic Biol Med 2009;47:559–567.
- Eisenstein RS, Tuazon PT, Schalinske KL, Anderson SA, Traugh JA. Iron-responsive element-binding protein. Phosphorylation by protein kinase C. J Biol Chem 1993;268: 27363–27370.
- Schalinske KL, Eisenstein RS. Phosphorylation and activation of both iron regulatory proteins 1 and 2 in HL-60 cells. J Biol Chem 1996;271:7168–7176.
- Zhang D, Meyron-Holtz E, Rouault TA. Renal iron metabolism: transferrin iron delivery and the role of iron regulatory proteins. J Am Soc Nephrol 2007;18:401–406.
- Veuthey T, D'Anna MC, Roque ME. Role of the kidney in iron homeostasis: renal expression of Prohepcidin, Ferroportin, and DMT1 in anemic mice. Am J Physiol Renal Physiol 2008;295:F1213–F1221.
- Wang J, Pantopoulos K. Regulation of cellular iron metabolism. Biochem J 2011;434:365–381.
- Harada N, Kanayama M, Maruyama A, Yoshida A, Tazumi K, Hosoya T, . Nrf2 regulates ferroportin 1-mediated iron efflux and counteracts lipopolysaccharide-induced ferroportin 1 mRNA suppression in macrophages. Arch Biochem Biophys 2011;508:101–109.
- Mastrogiannaki M, Matak P, Keith B, Simon MC, Vaulont S, Peyssonnaux C, . HIF-2alpha, but not HIF-1alpha, promotes iron absorption in mice. J Clin Invest 2009;119:1159–1166.
- Taylor M, Qu A, Anderson ER, Matsubara T, Martin A, Gonzalez FJ, . Hypoxia-inducible factor-2a mediates the adaptive increase of intestinal ferroportin during iron deficiency in mice. Gastroenterol 2011;140:2044–2055.
- Haase VH. Hypoxia-inducible factors in the kidney. Am J Physiol Renal Physiol 2006;291:F271–F281.
- Haase VH. Hypoxic regulation of erythropoiesis and iron metabolism. Am J Physiol Renal Physiol 2010;299: F1–F13.
- Poss KD, Tonegawa S. Heme oxygenase 1 is required for mammalian iron reutilization. Proc Natl Acad Sci U S A. 1997;94:10919–1024.
- Brown NM, Anderson SA, Steffen DW, Carpenter TB, Kennedy MC, Walden WE, . Novel role of phosphorylation in Fe-S cluster stability revealed by phosphomimetic mutations at Ser-138 of iron regulatory protein 1. Proc Natl Acad Sci U S A 1998;95:15235–15240.
- Fillebeen C, Chahine D, Caltagirone A, Segal P, Pantopoulos K. A phosphomimetic mutation at Ser-138 renders iron regulatory protein 1 sensitive to iron-dependent degradation. Mol Cell Biol 2003;23:6973–6981.
- Fillebeen C, Caltagirone A, Martelli A, Moulis JM, Pantopoulos K. IRP1 Ser-711 is a phosphorylation site, critical for regulation of RNA-binding and aconitase activities. Biochem J 2005;388:143–150.
- Konishi H, Tanaka M, Takemura Y, Matsuzaki H, Ono Y, Kikkawa U, . Activation of protein kinase C by tyrosine phosphorylation in response to H2O2. Proc Natl Acad Sci U S A 1997;94:11233–11237.
- Schalinske KL, Anderson SA, Tuazon PT, Chen OS, Kennedy MC, Eisenstein RS, . The iron-sulfur cluster of iron regulatory protein 1 modulates the accessibility of RNA binding and phosphorylation sites. Biochemistry 1997;36: 3950–3958.