Body temperature modulates the antioxidant and acute immune responses to exercise

References

• Ferrer MD, Tauler P, Sureda A, Tur JA, Pons A. Antioxidant regulatory mechanisms in neutrophils and lymphocytes after intense exercise. J Sports Sci 2009;27:49–58.
   PubMed Web of Science ®Google Scholar
• Tauler P, Aguilo A, Gimeno I, Guix P, Tur JA, Pons A, . Different effects of exercise tests on the antioxidant enzyme activities in lymphocytes and neutrophils. J Nutr Biochem 2004;15:479–484.
   PubMed Web of Science ®Google Scholar
• Ferrer MD, Tauler P, Sureda A, Pujol P, Drobnic F, Tur JA, . A soccer match's ability to enhance lymphocyte capability to produce ROS and induce oxidative damage. Int J Sport Nutr Exerc Metab 2009;19:243–258.
   PubMed Web of Science ®Google Scholar
• Sureda A, Ferrer MD, Tauler P, Romaguera D, Drobnic F, Pujol P, . Effects of exercise intensity on lymphocyte H2O2 production and antioxidant defences in soccer players. Br J Sports Med 2009;43:186–190.
   PubMed Web of Science ®Google Scholar
• Sureda A, Ferrer MD, Tauler P, Tur JA, Pons A. Lymphocyte antioxidant response and H2O2 production after a swimming session: gender differences. Free Radic Res 2008;42:312–319.
   PubMed Web of Science ®Google Scholar
• Sureda A, Ferrer MD, Tauler P, Maestre I, Aguilo A, Cordova A, . Intense physical activity enhances neutrophil antioxidant enzyme gene expression. Immunocytochemistry evidence for catalase secretion. Free Radic Res 2007;41: 874–883.
   PubMed Web of Science ®Google Scholar
• Khassaf M, McArdle A, Esanu C, Vasilaki A, McArdle F, Griffiths RD, . Effect of vitamin C supplements on antioxidant defence and stress proteins in human lymphocytes and skeletal muscle. J Physiol 2003;549:645–652.
   PubMed Web of Science ®Google Scholar
• Pedersen BK, Bruunsgaard H, Klokker M, Kappel M, MacLean DA, Nielsen HB, . Exercise-induced immunomodulation – Possible roles of neuroendocrine and metabolic factors. Int J Sports Med 1997;18:S2–S7.
   PubMed Web of Science ®Google Scholar
• Kayashima S, Ohno H, Fujioka T, Taniguchi N, Nagata N. Leucocytosis as a marker of organ damage induced by chronic strenuous physical exercise. Eur J Appl Physiol Occup Physiol 1995;70:413–420.
   PubMed Web of Science ®Google Scholar
• Lambert GP, Gisolfi CV, Berg DJ, Moseley PL, Oberley LW, Kregel KC, . Selected contribution: Hyperthermia- induced intestinal permeability and the role of oxidative and nitrosative stress. J Appl Physiol 2002;92:1750–1761; discussion 1749.
   PubMed Web of Science ®Google Scholar
• Pearson J, Low DA, Stohr E, Kalsi K, Ali L, Barker H, . Hemodynamic responses to heat stress in the resting and exercising human leg: insight into the effect of temperature on skeletal muscle blood flow. Am J Physiol Regul Integr Comp Physiol 2011;300:R663–R673.
   PubMed Web of Science ®Google Scholar
• Cheung SS, Sleivert GG. Multiple triggers for hyperthermic fatigue and exhaustion. Exerc Sport Sci Rev 2004;32:100–106.
   PubMed Web of Science ®Google Scholar
• Nybo L. Exercise and heat stress: cerebral challenges and consequences. Prog Brain Res 2007;162:29–43.
   PubMed Web of Science ®Google Scholar
• Gonzalez-Alonso J, Teller C, Andersen SL, Jensen FB, Hyldig T, Nielsen B, . Influence of body temperature on the development of fatigue during prolonged exercise in the heat. J Appl Physiol 1999;86:1032–1039.
   PubMed Web of Science ®Google Scholar
• Peake J, Peiffer JJ, Abbiss CR, Nosaka K, Okutsu M, Laursen PB, . Body temperature and its effect on leukocyte mobilization, cytokines and markers of neutrophil activation during and after exercise. Eur J Appl Physiol 2008;102:391–401.
   PubMed Web of Science ®Google Scholar
• McAnulty SR, McAnulty L, Pascoe DD, Gropper SS, Keith RE, Morrow JD, . Hyperthermia increases exercise- induced oxidative stress. Int J Sports Med 2005;26: 188–192.
   PubMed Web of Science ®Google Scholar
• Dieing A, Ahlers O, Hildebrandt B, Kerner T, Tamm I, Possinger K, . The effect of induced hyperthermia on the immune system. Prog Brain Res 2007;162:137–152.
   PubMed Web of Science ®Google Scholar
• Ahlers O, Hildebrandt B, Dieing A, Deja M, Bohnke T, Wust P, . Stress induced changes in lymphocyte subpopulations and associated cytokines during whole body hyperthermia of 41.8–42.2°C. Eur J Appl Physiol 2005;95:298–306.
   PubMed Web of Science ®Google Scholar
• Buhring M, Bork-Wolwer L, Krippner H. Peripheral T lymphocytopenia under exogenous thermal stress. Cancer 1978;42:2794–2797.
   PubMed Web of Science ®Google Scholar
• Dieing A, Ahlers O, Kerner T, Wust P, Felix R, Loffel J, . Whole body hyperthermia induces apoptosis in subpopulations of blood lymphocytes. Immunobiology 2003;207:265–273.
   PubMed Web of Science ®Google Scholar
• Mestre-Alfaro A, Ferrer MD, Sureda A, Tauler P, Martinez E, Bibiloni MM, . Phytoestrogens enhance antioxidant enzymes after swimming exercise and modulate sex hormone plasma levels in female swimmers. Eur J Appl Physiol 2011; 111:2281–2294.
   PubMed Web of Science ®Google Scholar
• Ferrer MD, Sureda A, Mestre A, Tur JA, Pons A. The double edge of reactive oxygen species as damaging and signaling molecules in HL60 cell culture. Cell Physiol Biochem 2010;25:241–252.
   PubMedGoogle Scholar
• Ferrer MD, Sureda A, Tauler P, Palacin C, Tur JA, Pons A, . Impaired lymphocyte mitochondrial antioxidant defences in variegate porphyria are accompanied by more inducible reactive oxygen species production and DNA damage. Br J Haematol 2010;149:759–767.
   PubMed Web of Science ®Google Scholar
• Shi T, Wang F, Stieren E, Tong Q. SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes. J Biol Chem 2005;280:13560–13567.
   PubMed Web of Science ®Google Scholar
• Schlicker C, Gertz M, Papatheodorou P, Kachholz B, Becker CF, Steegborn C, . Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5. J Mol Biol 2008;382:790–801.
   PubMed Web of Science ®Google Scholar
• North BJ, Sinclair DA. Sirtuins: a conserved key unlocking AceCS activity. Trends Biochem Sci 2007;32:1–4.
   PubMed Web of Science ®Google Scholar
• Boyum A. Separation of white blood cells. Nature 1964;204:793–794.
   PubMed Web of Science ®Google Scholar
• Aebi HE. Catalase. In: Bergmeyer H, (ed.), Methods in Enzymatic Analysis. Basel: Verlag Chemic; 1984. pp. 273–286.
   Google Scholar
• Goldberg DM SR. Glutathione reductase. In: Bergmeyer H, (ed.), Methods in enzymatic analysis. Basel: Verlag Chemic; 1984. pp. 258–265.
   Google Scholar
• Flohe L, Gunzler WA. Assays of glutathione peroxidase. Methods Enzymol 1984;105:114–121.
   PubMed Web of Science ®Google Scholar
• McCord JM, Fridovich I. Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). J Biol Chem 1969;244:6049–6055.
   PubMed Web of Science ®Google Scholar
• Erdelmeier I, Gerard-Monnier D, Yadan JC, Chaudiere J. Reactions of N-methyl-2-phenylindole with malondialdehyde and 4-hydroxyalkenals. Mechanistic aspects of the colorimetric assay of lipid peroxidation. Chem Res Toxicol 1998;11:1184–1194.
   PubMed Web of Science ®Google Scholar
• Cannon S, Blumberg J. Acute phase immune responses in exercise. In: Sen CK, Packer L, Hänninen O, (eds.), Handbook of Oxidants and Antioxidants in Exercise. Amsterdam: Elsevier Science B.V.; 2000. pp. 177–194.
   Google Scholar
• Mitchell JB, Dugas JP, McFarlin BK, Nelson MJ. Effect of exercise, heat stress, and hydration on immune cell number and function. Med Sci Sports Exerc 2002;34: 1941–1950.
   PubMed Web of Science ®Google Scholar
• Brenner I, Shek PN, Zamecnik J, Shephard RJ. Stress hormones and the immunological responses to heat and exercise. Int J Sports Med 1998;19:130–143.
   PubMed Web of Science ®Google Scholar
• McFarlin BK, Mitchell JB. Exercise in hot and cold environments: differential effects on leukocyte number and NK cell activity. Aviat Space Environ Med 2003;74:1231–1236.
   PubMed Web of Science ®Google Scholar
• Ostberg JR, Ertel BR, Lanphere JA. An important role for granulocytes in the thermal regulation of colon tumor growth. Immunol Invest 2005;34:259–272.
   PubMed Web of Science ®Google Scholar
• Gibbs BF. Human basophils as effectors and immunomodulators of allergic inflammation and innate immunity. Clin Exp Med 2005;5:43–49.
   PubMed Web of Science ®Google Scholar
• Howarth PH, Pao GJ, Church MK, Holgate ST. Exercise and isocapnic hyperventilation-induced bronchoconstriction in asthma: relevance of circulating basophils to measurements of plasma histamine. J Allergy Clin Immunol 1984;73:391–399.
   PubMed Web of Science ®Google Scholar
• Sureda A, Tauler P, Aguilo A, Cases N, Fuentespina E, Cordova A, . Relation between oxidative stress markers and antioxidant endogenous defences during exhaustive exercise. Free Radic Res 2005;39:1317–1324.
   PubMed Web of Science ®Google Scholar
• Tauler P, Ferrer MD, Sureda A, Pujol P, Drobnic F, Tur JA, . Supplementation with an antioxidant cocktail containing coenzyme Q prevents plasma oxidative damage induced by soccer. Eur J Appl Physiol 2008;104:777–785.
   PubMed Web of Science ®Google Scholar
• Shinkai S, Shore S, Shek PN, Shephard RJ. Acute exercise and immune function. Relationship between lymphocyte activity and changes in subset counts. Int J Sports Med 1992;13:452–461.
   PubMed Web of Science ®Google Scholar
• Onyango P, Celic I, McCaffery JM, Boeke JD, Feinberg AP. SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria. Proc Natl Acad Sci USA 2002;99:13653–13658.
   PubMed Web of Science ®Google Scholar
• Ahn BH, Kim HS, Song S, Lee IH, Liu J, Vassilopoulos A, . A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis. Proc Natl Acad Sci USA 2008;105:14447–14452.
   PubMed Web of Science ®Google Scholar
• Marfe G, Tafani M, Pucci B, Di Stefano C, Indelicato M, Andreoli A, . The effect of marathon on mRNA expression of anti-apoptotic and pro-apoptotic proteins and sirtuins family in male recreational long-distance runners. BMC Physiol 2010;10:7.
   PubMedGoogle Scholar
• Kregel KC. Heat shock proteins: modifying factors in physiological stress responses and acquired thermotolerance. J Appl Physiol 2002;92:2177–2186.
   PubMed Web of Science ®Google Scholar
• McClung JP, Hasday JD, He JR, Montain SJ, Cheuvront SN, Sawka MN, . Exercise-heat acclimation in humans alters baseline levels and ex vivo heat inducibility of HSP72 and HSP90 in peripheral blood mononuclear cells. Am J Physiol Regul Integr Comp Physiol 2008;294: R185–R191.
   PubMed Web of Science ®Google Scholar