Methylglyoxal induces oxidative stress and mitochondrial dysfunction in osteoblastic MC3T3-E1 cells

References

• Phillips SA, Thornalley PJ. The formation of methylglyoxal from triose phosphates. Investigation using a specific assay for methylglyoxal. Eur J Biochem 1993;212:101–105.
   PubMedGoogle Scholar
• Zou Z, Wu L, Ding H, Wang Y, Zhang Y, Chen X, et al. MicroRNA-30a sensitizes tumor cells to cis-platinum via suppressing beclin 1-mediated autophagy. J Biol Chem 2012; 287:4148–4156.
   PubMed Web of Science ®Google Scholar
• Chaplen FW, Fahl WE, Cameron DC. Detection of methylglyoxal as a degradation product of DNA and nucleic acid components treated with strong acid. Anal Biochem 1996;236:262–269.
   PubMed Web of Science ®Google Scholar
• Wang J, Chang T. Methylglyoxal content in drinking coffee as a cytotoxic factor. J Food Sci 2010;75:H167–171.
   PubMed Web of Science ®Google Scholar
• Munch G, Thome J, Foley P, Schinzel R, Riederer P. Advanced glycation endproducts in ageing and Alzheimer's disease. Brain Res Rev 1997;23:134–143.
   PubMed Web of Science ®Google Scholar
• Ahmed N. Advanced glycation endproducts–role in pathology of diabetic complications. Diabetes Res Clin Pract 2005;67: 3–21.
   PubMed Web of Science ®Google Scholar
• Raj DSC, Choudhury D, Welbourne TC, Levi M. Advanced glycation end products: a nephrologist's perspective. Am J Kidney Dis 2000;35:365–380.
   PubMed Web of Science ®Google Scholar
• Bonnefont-Rousselot D. Glucose and reactive oxygen species. Curr Opin Clin Nutr Metab Care 2002;5:561–568.
   PubMed Web of Science ®Google Scholar
• Petersen DR, Doorn JA. Reactions of 4-hydroxynonenal with proteins and cellular targets. Free Radical Biol Med 2004; 37:937–945.
   PubMed Web of Science ®Google Scholar
• McLellan AC, Thornalley PJ, Benn J, Sonksen PH. Glyoxalase system in clinical diabetes mellitus and correlation with diabetic complications. Clin Sci (London) 1994;87: 21–29.
   PubMed Web of Science ®Google Scholar
• Chaplen FW, Fahl WE, Cameron DC. Evidence of high levels of methylglyoxal in cultured Chinese hamster ovary cells. Proc Natl Acad Sci USA 1998;95:5533–5538.
   PubMed Web of Science ®Google Scholar
• Chang T, Wang R, Wu L. Methylglyoxal-induced nitric oxide and peroxynitrite production in vascular smooth muscle cells. Free Radic Biol Med 2005;38:286–293.
   PubMed Web of Science ®Google Scholar
• Addabbo F, Ratliff B, Park HC, Kuo M, Ungvari Z, Csiszar A, et al. The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach. Am J Pathol 2009;174:34–43.
   PubMed Web of Science ®Google Scholar
• Nisoli E, Clementi E, Paolucci C, Cozzi V, Tonello C, Sciorati C, et al. Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide. Science 2003;299:896–899.
   PubMed Web of Science ®Google Scholar
• Nisoli E, Falcone S, Tonello C, Cozzi V, Palomba L, Fiorani M, et al. Mitochondrial biogenesis by NO yields functionally active mitochondria in mammals. Proc Natl Acad Sci USA 2004;101:16507–16512.
   PubMed Web of Science ®Google Scholar
• Nisoli E, Tonello C, Cardile A, Cozzi V, Bracale R, Tedesco L, et al. Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. Science 2005;310: 314–317.
   PubMed Web of Science ®Google Scholar
• Thornalley PJ. The glyoxalase system in health and disease. Mol Aspects Med 1993;14:287–371.
   PubMed Web of Science ®Google Scholar
• Uotila L. Glutathione thiol esterases. In: Dolphin D, Poulson R, Avramovic O. (eds.). Glutathione: Chemical, biochemical and medical aspects, coenzymes and cofactors. New York: Wiley-Interscience; 1989. pp. 767–804.
   Google Scholar
• Ahmed N, Battah S, Karachalias N, Babaei-Jadidi R, Horanyi M, Baroti K, et al. Increased formation of methylglyoxal and protein glycation, oxidation and nitrosation in triosephosphate isomerase deficiency. Biochim Biophys Acta 2003;1639: 121–132.
   PubMedGoogle Scholar
• Hipkiss AR. Carnosine, a protective, anti-ageing peptide?Int J Biochem Cell Biol 1998;30:863–868.
   PubMed Web of Science ®Google Scholar
• Munch G, Kuhla B, Luth HJ, Arendt T, Robinson SR. Anti-AGEing defences against Alzheimer's disease. Biochem Soc Trans 2003;31:1397–1399.
   PubMed Web of Science ®Google Scholar
• Webster J, Urban C, Berbaum K, LoskeC, Alpar A, Gartner U, et al. The carbonyl scavengers aminoguanidine and tenilsetam protect against the neurotoxic effects of methylglyoxal. Neurotox Res 2005;7:95–101.
   PubMed Web of Science ®Google Scholar
• Thornalley PJ. Glyoxalase I-structure, function and a critical role in the enzymatic defence against glycation. Biochem Soc Trans 2003;31:1343–1348.
   PubMed Web of Science ®Google Scholar
• Kikuchi S, Shinpo K, Moriwaka F, Makita Z, Miyata T, Tashiro K. Neurotoxicity of methylglyoxal and 3-deoxyglucosone on cultured cortical neurons: synergism between glycation and oxidative stress, possibly involved in neurodegenerative diseases. J Neurosci Res 1999;57: 280–289.
   PubMed Web of Science ®Google Scholar
• Shinpo K, Kikuchi S, Sasaki H, Ogata A, Moriwaka F, Tashiro K. Selective vulnerability of spinal motor neurons to reactive dicarbonyl compounds, intermediate products of glycation, in vitro: implication of inefficient glutathione system in spinal motor neurons. Brain Res 2000;861:151–159.
   PubMed Web of Science ®Google Scholar
• Du J, Suzuki H, Nagase FA, Akhand A, Yokoyama T, Miyata T, et al. Methylglyoxal induces apoptosis in Jurkat leukemia cells by activating c-Jun N-terminal kinase. Cell Biochem 2000;77:333–344.
   PubMed Web of Science ®Google Scholar
• de Arriba SG, Krugel U, Ralf R, Vissiennon Z, Verdaguer E, Lewerenz A, et al. Carbonyl stress and NMDA receptor activation contribute to methylglyoxal neurotoxicity. Free Radic Biol Med 2006;40:779–790.
   PubMed Web of Science ®Google Scholar
• Bouillon R. Diabetic bone disease. Calcif Tissue Int 1991; 49:155–160.
   PubMed Web of Science ®Google Scholar
• Kayath MJ, Tavares EF, Dib SA, Vieira JG. Prospective bone mineral density evaluation in patients with insulin-dependent diabetes mellitus. J Diabet Complications 1998;12:133–139.
   Google Scholar
• Nicodemus KK, Folsom AR. Type 1 and type 2 diabetes and incident hip fractures in postmenopausal women. Diabetes Care 2001;24:1192–1197.
   PubMed Web of Science ®Google Scholar
• Yamagishi S, Nakamura K, Inoue H. Possible participation of advanced glycation end products in the pathogenesis of osteoporosis in diabetic patients. Med Hypotheses 2005; 65:1013–1015.
   PubMed Web of Science ®Google Scholar
• Chan WH, Wu HJ, Shiao NH. Apoptotic signaling in methylglyoxal-treated human osteoblasts involves oxidative stress, c-Jun N-terminal kinase, caspase-3, and p21-activated kinase 2. J Cell Biochem 2007;100:1056–1069.
   PubMed Web of Science ®Google Scholar
• Jakubowski W, Bartosz G. 2,7-Dichlorofluorescin oxidation and reactive oxygen species: What does it measure?Cell Biol Int 2000;24:757–760.
   PubMed Web of Science ®Google Scholar
• Schroeder P, Pohl C, Calles C, Marks C, Wild S, Krutmann J. Cellular response to infrared radiation involves retrograde mitochondrial signaling. Free Radic Biol Med 2007;43: 128–135.
   PubMed Web of Science ®Google Scholar
• Nomura K, Imai T, Kobayashi T, Nakagawa Y. Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis. Biochem J 2000;351:183–193.
   PubMed Web of Science ®Google Scholar
• Wang H, Meng QH, Chang T, Wu L. Fructose-induced peroxynitrite production is mediated by methylglyoxal in vascular smooth muscle cells. Life Sci 2006;79:2448–2454.
   PubMed Web of Science ®Google Scholar
• Thornalley PJ, Tisdale MJ. Inhibition of proliferation of human promyelocytic leukaemia HL60 cells by S-D-lactoylglutathione in vitro. Leuk Res 1988;12:897–904.
   PubMed Web of Science ®Google Scholar
• Oyama Y, Hayashi A, Ueha T, Maekawa K. Characterization of 2′,7′-dichlorofluorescin fluorescence in dissociated mammalian brain neurons: estimation on intracellular content of hydrogen peroxide. Brain Res 1994;635:113–117.
   PubMed Web of Science ®Google Scholar
• Mukhopadhyay P, Rajesh M, Kashiwaya Y, Haskó G, Pacher P. Simple quantitative detection of mitochondrial superoxide production in live cells. Biochem Biophys Res Commun 2007;358:203–208.
   PubMed Web of Science ®Google Scholar
• Petit JM, Maftah A, Ratinaud MH, Julien R. 10N-nonyl acridine orange interacts with cardiolipin and allows the quantification of this phospholipid in isolated mitochondria. Eur J Biochem 1992;209:267–273.
   PubMedGoogle Scholar
• Sudo H, Kodama H, Amagai Y, Yamamoto S, Kasai S. In vitro differentiation and calcification in new clonal osteogenic cell line derived from newborn mouse calvariae. J Cell Biol 1983;96:191–198.
   PubMed Web of Science ®Google Scholar
• Ogawa N, Yamaguchi T, Yano S, Yamauchi M, Yamamoto M, Sugimoto T. The combination of high glucose and advanced glycation end-products (AGEs) inhibits the mineralization of osteoblastic MC3T3-E1 cells through glucose-induced increase in the receptor for AGEs. Horm Metab Res 2007; 39:871–875.
   Google Scholar
• Frye EB, Degenhardt TP, Thrope SR. Role of the Maillard reaction in aging of tissue proteins. J Biol Chem 1998;273:18714–18719.
   PubMed Web of Science ®Google Scholar
• Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger C. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J Immunol Methods 1995; 184:39–51.
   PubMed Web of Science ®Google Scholar
• Yamagishi S, Nakamura K, Matsui T. Advanced glycation end products (AGEs) and their receptor (RAGE) system in diabetic retinopathy. Curr Drug Discov Technol 2006;6:83–88.
   Google Scholar
• Yagihashi S, Diabetic neuropathy. Nippon Rinsho 2006;3: 155–160.
   Google Scholar
• Kurowski R, Mantitus J. Advanced glycation end products (AGEs) and renal failure. Przeql Lek 2006;63:203–208.
   Google Scholar
• Abordo EA, Minhas HS, Thornalley PJ. Accumulation of alpha-oxoaldehydes during oxidative stress: a role in cytotoxicity. Biochem Pharmacol 1999;58:641–648.
   PubMed Web of Science ®Google Scholar
• Sheader EA, Benson RS, Best L. Cytotoxic action of methylglyoxal on insulin-secreting cells. Biochem Pharmacol 2001;61:1381–1386.
   PubMed Web of Science ®Google Scholar
• Amicarelli F, Colafarina S, Cattani F, Cimini A, Di Ilio C, Ceru MP, Miranda M. Scavenging system efficiency is crucial for cell resistance to ROS mediated methylglyoxal injury. Free Radic Biol Med 2003;35:856–871.
   Google Scholar
• Wang H, Joseph JA. Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader. Free Radic Biol Med 1999;27:612–616.
   PubMed Web of Science ®Google Scholar
• Davidson SM, Duchen MR. Endothelial mitochondria: contributing to vascular function and disease. Circ Res 2007;100:1128–1141.
   PubMed Web of Science ®Google Scholar
• Nishikawa T, Edelstein D, Du XL, Yamagishi S, Matsumura T, Kaneda Y, et al. Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 2000;404:787–890.
   PubMed Web of Science ®Google Scholar
• Du Y, Miller CM, Kern TS. Hyperglycemia increases mitochondrial superoxide in retina and retinal cells. Free Radic Biol Med 2003;35:1491–1499.
   PubMed Web of Science ®Google Scholar
• Rosca MG, Mustata TG, Kinter MT, Ozdemir AM, Kern TS, Szweda LI, et al. Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation. Am J Physiol Renal Physiol 2005;289:420–430.
   PubMed Web of Science ®Google Scholar
• Hink U, Li H, Mollnau H, Oelze M, Matheis E, Hartmann M, et al. Mechanisms underlying endothelial dysfunction in diabetes mellitus. Circ Res 2001;88:e14–e22.
   PubMed Web of Science ®Google Scholar
• Kagan VE, Tyurin VA, Jiang J, Tyurina YY, Ritov VB, Amoscato AA, et al. Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors. Nat Chem Biol 2005;1:223–232.
   PubMed Web of Science ®Google Scholar
• Wiswedel I, Gardemann A, Storch A, Peter D, Schild L. Degradation of phospholipids by oxidative stress-exceptional significance of cardiolipin. Free Radic Res 2010;44: 135–145.
   PubMed Web of Science ®Google Scholar
• Paradies G, Petrosillo G, Paradies V, Ruggiero FM. Mitochondrial dysfunction in brain aging: role of oxidative stress and cardiolipin. Neurochem Int 2011;58:447–457.
   PubMed Web of Science ®Google Scholar
• Petrosillo G, Portincasa P, Grattagliano I, Casanova G, Matera M, Ruggiero FM, et al. Mitochondrial dysfunction in rat with nonalcoholic fatty liver Involvement of complex I, reactive oxygen species and cardiolipin. Biochim Biophys Acta 2007;1767:1260–1267.
   PubMed Web of Science ®Google Scholar
• Ly JD, Grubb DR, Lawen A. The mitochondrial membrane potential in apoptosis; an update. Apoptosis: An International Journal on Programmed Cell Death. Apoptosis 2003;8: 115–128.
   PubMed Web of Science ®Google Scholar
• Wang H, Liu J, Wu L. Methylglyoxal-induced mitochondrial dysfunction in vascular smooth muscle cells. Biochem Pharmacol 2009;77:1709–1716.
   PubMed Web of Science ®Google Scholar
• Gross SS, Wolin MS. Nitric oxide: pathophysiological mechanisms. Annu Rev Physiol 1995;57:737–769.
   PubMed Web of Science ®Google Scholar
• Brown GC, Cooper CE. Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase. FEBS Lett 1994;356: 295–298.
   PubMed Web of Science ®Google Scholar
• Almeida A, Moncada S, Bolanos JP. Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway. Nat Cell Biol 2004;6:45–51.
   PubMed Web of Science ®Google Scholar
• Beltrán B, Orsi A, Clementi E, Moncada S. Oxidative stress and S-nitrosylation of proteins in cells. Br J Pharmacol 2000;129:953–960.
   PubMed Web of Science ®Google Scholar
• Ihnat MA, Thorpe JE, Ceriello A. Hypothesis: the ‘metabolic memory’, the new challenge of diabetes. Diabet Med 2007; 24:582–586.
   PubMed Web of Science ®Google Scholar
• Carrington SJ, Douglas KT. The glyoxalase enigma-the biological consequences of a ubiquitous enzyme. IRCS Med Sci 1986;14:763–768.
   Google Scholar
• Zhong Q, Kowluru RA. Role of histone acetylation in the development of diabetic retinopathy and the metabolic memory phenomenon. J Cell Biochem 2010;110:1306–1313.
   Google Scholar
• Atkins TW, Thornalley PJ. Modification of the red blood cell glyoxalase system in genetically obese (ob/ob) and streptozotocin-induced diabetic mice. Diabetes Res 1989;11: 125–129.
   PubMedGoogle Scholar
• Thornalley PJ. The glyoxalase system: new developments towards functional characterization of a metabolic pathway fundamental to biological life. Biochem J 1990;269:1–11.
   PubMed Web of Science ®Google Scholar
• Sharma-Luthra R, Kale RK. Age related changes in the activity of the glyoxalase system. Mech Ageing Dev 1994;73:39–45.
   Google Scholar
• Leoncini G, Maresca M, Bonsignore A. The effect of methylglyoxal on glycolitic enzymes. FEBS Lett 1980;117: 17–18.
   PubMed Web of Science ®Google Scholar
• Schauenstein E, Esterbauer H, Zollner H.α-Dicarbonyls. Aldehydes in biological systems. London: Pion Ltd.; 1977. pp. 112–157.
   Google Scholar
• Baskaran S, Balasubramanian KA. Effect of methylglyoxal on protein thiol and amino groups in isolated rat erythrocytes and colonocytes and activity of various brush border enzymes. Indian J Biochem Biophys 1990;27:13–17.
   Google Scholar