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Research Article

Ebselen pretreatment attenuates ischemia/reperfusion injury and prevents hyperglycemia by improving hepatic insulin signaling and β-cell survival in gerbils

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Pages 864-874 | Received 06 Mar 2014, Accepted 17 Apr 2014, Published online: 19 May 2014

References

  • Danielisová V, Gottlieb M, Némethová M, Burda J. Activities of endogenous antioxidant enzymes in the cerebrospinal fluid and the hippocampus after transient forebrain ischemia in rat. J Neurol Sci 2007;253:61–65.
  • White BC, Sullivan JM, DeGracia DJ, O’Neil BJ, Neumar RW, Grossman LI, et al. Brain ischemia and reperfusion: molecular mechanisms of neuronal injury. J Neurol Sci 2000;179:S1–S33.
  • Zeng L, Wang Y, Liu J, Wang L, Weng S, Chen K, et al. Pro-inflammatory cytokine network in peripheral inflammation response to cerebral ischemia. Neurosci Lett 2013; 548:4–9.
  • Yan BC, Kim SK, Park JH, Ahn JH, Lee CH, Yoo KY, et al. Comparison of inflammatory cytokines changes in the hippocampal CA1 region between the young and adult gerbil after transient cerebral ischemia. Brain Res 2012;1461:64–75.
  • Capes SE, Hunt D, Malmberg K, Pathak P, Gerstein HC. Stress hyperglycemia and prognosis of stroke in nondiabetic and diabetic patients: a systematic overview. Stroke 2001; 32:2426–2432.
  • Pickup JC. Inflammation and activated innate immunity in the pathogenesis of type 2 diabletes. Diab Care 2004;27:813–823.
  • Baird TA, Parsons MW, Phanh T, Butcher KS, Desmond PM, Tress BM, et al. Persistent poststroke hyperglycemia is independently associated with infarct expansion and worse clinical outcome. Stroke 2003;34:2208–2214.
  • Yang HJ, Hwang JT, Kwon DY, Kim MJ, Kang S, Park S. Yuzu extract prevents cognitive decline and impaired glucose homeostasis in β-amyloid-infused rats. J Nutr 2013;143: 1093–1099.
  • DeFronzo RA, Abdul-Ghani MA. Preservation of β-cell function: the key to diabetes prevention. J Clin Endocrinol Metab 2011;96:2354–2366.
  • Seino S, Shibasaki T, Minami K. Dynamics of insulin secretion and the clinical implications for obesity and diabetes. J Clin Invest 2011;121:2118–2125.
  • Park S, Hong SM, Lee JE, Sung SR. Exercise improves glucose homeostasis impaired by a high fat diet through potentiating pancreatic β-cell function and mass through IRS2 in diabetic rats. J Appl Physiol 2007;103:1764–1771.
  • Herchuelz A, Nguidjoe E, Jiang L, Pachera N. β-Cell preservation and regeneration in diabetes by modulation of β-cell Ca²? homeostasis. Diabetes Obes Metab 2012;14:S136–S142.
  • Park S, Kim DS, Kang S, Kwon DY. Ischemic hippocampal cell death induces glucose dysregulation by attenuating glucose-stimulated insulin secretion and a high fat diet exacerbates this condition. Life Sci 2011;88:766–773.
  • Dinarello CA, Donath MY, Mandrup-Poulsen T. Role of IL-1beta in type 2 diabetes. Curr Opin Endocrinol Diabetes Obes 2010;17:314–321.
  • Donath MY, Böni-Schnetzler M, Ellingsgaard H, Halban PA, Ehses JA. Cytokine production by islets in health and diabetes: cellular origin, regulation and function. Trends Endocrinol Metab 2010;21:261–267.
  • Lenzen S. The mechanisms of alloxan- and streptozotocin-induced diabetes. Diabetologia 2008;51:216–226.
  • Tunc T, Uysal B, Atabek C, Kesik V, Caliskan B, Oztas E, et al. Erdosteine and ebselen as useful agents in intestinal ischemia/reperfusion injury. J Surg Res 2009;155:210–216.
  • Yamaguchi T, Sano K, Takakura K, Saito I, Shinohara Y, Asano T, Yasuhara H, et al.; for the Ebselen Study Group. Ebselen in acute ischemic stroke a placebo-controlled double-blind clinical trial. Stroke 1998;29:12–17.
  • Wang X, Vatamaniuk MZ, Roneker CA, Pepper MP, Hu LG, Simmons RA, et al. Knockouts of SOD1 and GPX1 exert different impacts on murine islet function and pancreatic integrity. Antioxid Redox Signal 2011;14:391–401.
  • Kirino T, Sano K. Fine structural nature of delayed neuronal death following ischemia in the gerbil hippocampus. Acta Neuropathol 1984;62:209–218.
  • Hudetz JA, Pagel PS. Neuroprotection by ketamine: a review of the experimental and clinical evidence. J Cardiothor Vasc Anesth 2010;24:131–142.
  • Langdon KD, Clarke J, Corbett D. Long-term exposure to high fat diet is bad for your brain: exacerbation of focal ischemic brain injury. Neuroscience 2011;182:82–87.
  • Lawner P, Laurent J, Simeone F, Fink E, Rubin E. Attenuation of ischemic brain edema by pentobarbital after carotid ligation in the gerbil. Stroke 1979;10:644–647.
  • Park S, Ahn IS, Kim DS. Central infusion of leptin improves insulin resistance and suppresses β-cell function, but not β-cell mass, primarily through the sympathetic nervous system in a type 2 diabetic rat model. Life Sci 2010;86:854–862.
  • Park S, Hong SM, Ahn IS. Can splenocytes enhance pancreatic β-cell function and mass in 90% pancreatectomized rats fed a high fat diet?Life Sci 2009;84:358–363.
  • Ahn EH, Kim DW, Shin MJ, Kwon SW, Kim YN, Kim DS, et al. Chlorogenic acid improves neuroprotective effect of PEP-1-ribosomal protein S3 against insult. Exp Neurobiol 2011;20:169–175.
  • Thanvi B, Robinson T. Complete occlusion of extracranial internal carotid artery: clinical features, pathophysiology, diagnosis and management. Postgrad Med J 2007;83: 95–99.
  • Hu J, Luo CX, Chu WH, Shan YA, Qian ZM, Zhu G, et al. 20-Hydroxyecdysone protects against oxidative stress-induced neuronal injury by scavenging free radicals and modulating NF-κB and JNK pathways. PLoS One 2012;7:e50764.
  • Drews G, Krippeit-Drews P, Düfer M. Oxidative stress and beta-cell dysfunction. Pflugers Arch 2010;460:703–718.
  • Henriksen EJ, Diamond-Stanic MK, Marchionne EM. Oxidative stress and the etiology of insulin resistance and type 2 diabetes. Free Radic Biol Med 2011;51:993–999.
  • Park S, Kim DS, Kang S. Exercise training attenuates cerebral ischemic hyperglycemia by improving hepatic insulin signaling and β-cell survival. Life Sci 2013;93:153–160.
  • Morel C, Standen CL, Jung DY, Gray S, Ong H, Flavell RA, et al. Requirement of JIP1-mediated c-Jun N-terminal kinase activation for obesity-induced insulin resistance. Mol Cell Biol 2010;30:4616–4625.
  • Tuncman G, Hirosumi J, Solinas G, Chang L, Karin M, Hotamisligil GS. Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance. Proc Natl Acad Sci USA 2006;103:10741–10746.
  • Goldstein BJ, Mahadev K, Wu X, Zhu L, Motoshima H. Role of insulin induced reactive oxygen species in the insulin signaling pathway. Antioxid Redox Signal 2005;7:1021–1031.
  • Loh K, Deng H, Fukushima A, Cai X, Boivin B, Galic S, et al. Reactive oxygen species enhance insulin sensitivity. Cell Metab 2009;10:260–272.
  • Iwakami S, Misu H, Takeda T, Sugimori M, Matsugo S, Kaneko S, Takamura T. Concentration-dependent dual effects of hydrogen peroxide on insulin signal transduction in H4IIEC hepatocytes. PLoS One 2011;6:e27401.

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