Mechanism of the anti-hypertensive property of the naturally occurring phenolic, malabaricone C in DOCA-salt rats

References

• World Health Organization. Mortality and burden of disease estimates for WHO member states in 2004, Geneva: WHO; 2004. Available from: http://www.whoint/entity/healthinfo/global_burden/disease/gbddeathdalycountryestimates 2004.xls [last accessed 18 Nov 2015].
   Google Scholar
• D’Agostino Sr. RB, Vasan RS, Pencina MJ, Wolf PA, Cobain M, Massaro JM, Kannel WB. General cardiovascular risk profile for use in primary care: the Framingham heart study. Circulation 2008;117:743–753.
   PubMed Web of Science ®Google Scholar
• Luscher TF. The endothelium and cardiovascular disease – a complex relation. N Engl J Med 1994;330:1081–1083.
   PubMed Web of Science ®Google Scholar
• Libby P. Current concepts of the pathogenesis of the acute coronary syndromes. Circulation 2001;104:365–372.
   PubMed Web of Science ®Google Scholar
• Hamilton CA, Miller WH, Al-Benna S, Brosnan MJ, Drummond RD, McBride MW, Dominiczak AF. Strategies to reduce oxidative stress in cardiovascular disease. Clin Sci 2004;106:219–234.
   PubMed Web of Science ®Google Scholar
• Luscher TF, Barton M. Biology of the endothelium. Clin Cardiol 1997;20:II–10.
   PubMed Web of Science ®Google Scholar
• Stanton HC. Experimental hypertension. In: Schwartz A, ed. Methods in pharmacology, vol. 1. New York: Appleton-Century Crofts, Educational Division, Meredith Corporation; 1975:125–150.
   Google Scholar
• Iyer A, Chan V, Brown L. The DOCA-salt hypertensive rat as a model of cardiovascular oxidative and inflammatory stress. Curr Cardiol Rev 2010;6:291–297.
   PubMedGoogle Scholar
• Vane JR, Anggard EE, Botting RM. Regulatory functions of the vascular endothelium. N Engl J Med 1990;323:27–36.
   PubMed Web of Science ®Google Scholar
• Moncada S, Vane JR. Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin. Pharmacol Rev 1978;30:293–331.
   PubMed Web of Science ®Google Scholar
• Kubo K, Kobayashi T, Kusama S, Sakai A, Ueda G. Effects of prostacyclin (PGI2) on hypoxic pulmonary vasoconstriction in the conscious adult sheep. Jpn Circ J 1985;49:685–691.
   PubMedGoogle Scholar
• Yu M, Gopalakrishnan V, Wilson TW, McNeill JR. Endothelin antagonist reduces hemodynamic responses to vasopressin in DOCA-salt hypertension. Am J Physiol Heart Circ Physiol 2001;281:H2511–H2517.
   Google Scholar
• Larivière R, Thibault G, Schiffrin EL. Increased endothelin-1 content in blood vessels of deoxycorticosterone acetate–salt hypertensive but not in spontaneously hypertensive rats. Hypertension 1993;21:294–300.
   PubMed Web of Science ®Google Scholar
• Yu M, Gopalakrishnan V, McNeill JR. Role of endothelin and vasopressin in DOCA-salt hypertension. Br J Pharmacol 2001;132:1447–1454.
   PubMed Web of Science ®Google Scholar
• Chan V, Hoey A, Brown L. Improved cardiovascular function with aminoguanidine in DOCA-salt hypertensive rats. Br J Pharmacol 2006;148:881–883.
   PubMed Web of Science ®Google Scholar
• Meng Z, Yu XH, Chen J, Li L, Li S. Curcumin attenuates cardiac fibrosis in spontaneously hypertensive rats through PPAR-γ activation. Acta Pharmacol Sin 2014;35:1247–1256.
   PubMed Web of Science ®Google Scholar
• Margetts BM, Beilin LJ, Vandongen R, Armstrong BK. Vegetarian diet in mild hypertension: a randomised controlled trial. BMJ 1986;293:1468–1471.
   PubMed Web of Science ®Google Scholar
• Appel LJ, Moore TJ, Obarzanek E, Vollmer WM, Svetkey LP, Sacks FM, et al. A clinical trial of the effects of dietary patterns on blood pressure. N Engl J Med 1997;33:1117–1124.
   Web of Science ®Google Scholar
• Hertog MG, Feskens EJ, Hollman PC, Katan MB, Kromhout D. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen elderly study. Lancet 1993;342:1007–1011.
   PubMed Web of Science ®Google Scholar
• Huxley RR, Neil HA. The relation between dietary flavonol intake and coronary heart disease mortality: a meta-analysis of prospective cohort studies. Eur J Clin Nutr 2003;57:904–908.
   PubMed Web of Science ®Google Scholar
• He FJ, Nowson CA, MacGregor GA. Fruit and vegetable consumption and stroke: meta-analysis of cohort studies. Lancet 2006;367:320–326.
   PubMed Web of Science ®Google Scholar
• Palani V, Senthilkumaran RK, Govindasamy S. Biochemical evaluation of antitumor effect of MuthuMarunthu (a herbal formulation) on experimental fibrosarcoma in rats. J Ethnopharmacol 1999;65:257–265.
   PubMed Web of Science ®Google Scholar
• Patro BS, Bauri AK, Mishra S, Chattopadhyay S. Antioxidant activity of Myristica malabarica extracts and their constituents. J Agric Food Chem 2005;53:6912–6918.
   PubMed Web of Science ®Google Scholar
• Banerjee D, Bauri AK, Guha RK, Bandyopadhyay SK, Chattopadhyay S. Healing properties of malabaricone B and malabaricone C against indomethacin-induced gastric ulceration and mechanism of action. Eur J Pharmacol 2008;578:300–312.
   PubMed Web of Science ®Google Scholar
• Hlavackova L, Janegova A, Ulicna O, Janega P, Cerna A, Babal P. Spice up the hypertension diet – curcumin and piperine prevent remodeling of aorta in experimental L-NAME induced hypertension. Nutr Metab (Lond) 2011;8:72. doi: 10.1186/1743-7075-8-72.
   PubMed Web of Science ®Google Scholar
• Han P, Shen FM, Xie HH, Chen YY, Miao CY, Mehta JL, Sassard J, Feng Su D. The combination of atenolol and amlodipine is better than their monotherapy for preventing end-organ damage in different types of hypertension in rats. J Cell Mol Med 2009;13:726–734.
   PubMed Web of Science ®Google Scholar
• Fenning A, Harrison G, Rose'meyer R, Hoey A, Brown L. L-Arginine attenuates cardiovascular impairment in DOCA-salt hypertensive rats. Am J Physiol Heart Circ Physiol 2005;289:H1408–H1416.
   PubMed Web of Science ®Google Scholar
• Chan V, Hoey A, Brown L. Improved cardiovascular function with aminoguanidine in DOCA-salt hypertensive rats. Br J Pharmacol 2006;148:902–908.
   PubMed Web of Science ®Google Scholar
• Folkow B. Physiological aspects of primary hypertension. Physiol Rev 1982;62:347–354.
   PubMed Web of Science ®Google Scholar
• Karam H, Heudes D, Gonzales MF, Loffler BM, Clozel M, Clozel JP. Respective role of humoral factors and blood pressure in aortic remodeling of DOCA hypertensive rats. Am J Hypertens 1996;9:991–998.
   PubMed Web of Science ®Google Scholar
• Pepine CJ, Handberg EM. The vascular biology of hypertension and atherosclerosis and intervention with calcium antagonists and angiotensin-converting enzyme inhibitors. Clin Cardiol 2001;24:V1–V5.
   Google Scholar
• Zhu Z. Window period for oxidative stress attenuating intervention (WPOS Theory). Am J Biomed Sci 2009;1:250–259.
   Google Scholar
• Manning RD, Tian N, Meng S. Oxidative stress and antioxidant treatment in hypertension and the associated renal damage. Am J Nephrol 2005;25:311–317.
   PubMed Web of Science ®Google Scholar
• McEniery CM. Novel therapeutic strategies for reducing arterial stiffness. Br J Pharmacol 2006;148:881–883.
   PubMed Web of Science ®Google Scholar
• Hughes AK, Stricklett P, Padilla E, Kohan DE. Effect of reactive oxygen species on endothelin-1 production by human mesangial cells. Kidney Int 1996;49:181–189.
   PubMed Web of Science ®Google Scholar
• Li L, Fink GD, Watts SW, Northcott CA, Galligan JJ, Pagano PJ, Chen AF. Endothelin-1 increases vascular superoxide via endothelinA–NADPH oxidase pathway in low-renin hypertension. Circulation 2003;107:1053–1058.
   PubMed Web of Science ®Google Scholar
• Ma XL, Gao F, Nelson AH, Lopez BL, Christopher TA, Yue TL, Barone FC. Oxidative inactivation of nitric oxide and endothelial dysfunction in stroke-prone spontaneous hypertensive rats. J Pharmacol Exp Ther 2001;298:879–885.
   PubMed Web of Science ®Google Scholar
• Zicha J, Kunes J, Lebl M, Pohlova I, Slaninova J, Jelinek J. Antidiuretic and pressor actions of vasopressin in age-dependent DOCA-salt hypertension. Am J Physiol Regul Integr Comp Physiol 1989;256:R138–R145.
   PubMed Web of Science ®Google Scholar
• Yu M, Gopalakrishnan V, McNeill JR. Hemodynamic effects of a selective endothelin-a receptor antagonist in deoxycorticosterone acetate-salt hypertensive rats. J Cardiovasc Pharmacol 1998;31:S262–S264.
   Google Scholar
• Quehenberger P, Bierhaus A, Fasching P, Muellner C, Klevesath M, Hong M, et al. Endothelin-1 transcription is controlled by nuclear factor-kB in AGE-stimulated cultured endothelial cells. Diabetes 2000;49:1561–1570.
   PubMed Web of Science ®Google Scholar
• Maity B, Yadav SK, Patro BS, Bandyopadhyay SK, Chattopadhyay S. Molecular mechanism of the anti-inflammatory activity of a natural diarylnonanoid, malabaricone C. Free Radic Biol Med 2012;52:1680–1691.
   PubMed Web of Science ®Google Scholar
• Deng LY, Schiffrin EL. Effects of endothelin on resistance arteries of DOCA-salt hypertensive rats. Am J Physiol 1992;262:H1782–H1787.
   PubMed Web of Science ®Google Scholar
• Uehara Y, Numabe A, Hirawa N, Ishimitsu T, Takada S, Sugimoto T, Yagi S. Alterations to the vascular vasodepressor prostaglandin system in DOCA-salt hypertensive rats and their enzymatic analysis. J Hypertens Suppl 1988;6:S392–394.
   Google Scholar
• Van de Voorde J, Leusen I. Endothelium dependent and independent relaxation of aortic rings from hypertensive rats. Am J Physiol 1986;250:H711–H717.
   PubMed Web of Science ®Google Scholar
• Perez-Vizcaino F, Duarte J, Andriantsitohaina R. Endothelial function and cardiovascular disease: effects of quercetin and wine polyphenols. Free Radic Res 2006;40:1054–1065.
   PubMed Web of Science ®Google Scholar
• Seifi B, Kadkhodaee M, Karimian SM, Zahmatkesh M, Xu J, Soleimani M. Evaluation of renal oxidative stress in the development of DOCA-salt induced hypertension and its renal damage. Clin Exp Hypertens 2010;32:90–97.
   PubMed Web of Science ®Google Scholar
• Mason RP, Kubant R, Jacob RF, Walter MF, Boychuk B, Malinski T. Effect of nebivolol on endothelial nitric oxide and peroxynitrite release in hypertensive animals: role of antioxidant activity. J Cardiovasc Pharmacol 2006;48:862–869.
   PubMed Web of Science ®Google Scholar
• Deoghare S, Kantharia ND. Effect of atenolol and enalapril treatment on oxidative stress parameters in patients with essential hypertension. Int J Basic Clin Pharmacol 2013;2:252–256.
   Google Scholar