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Original Article

Synergistic Effects of Cu(II) and Dimethylammonium 2,4-Dichlorophenoxyacetate (U46 D Fluid) on PM2 DNA and Mechanism of Dna Damage

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Pages 123-130 | Received 01 Mar 1991, Published online: 07 Jul 2009

References

  • Jacobi H., Witte I. Synergistic effects of U46 D Fluid (dimethylammonium salt of 2,4-D) and CuCl2 on cytotoxicity and DNA repair in human fibroblasts. Toxicology Letters 1991; 58: 159–167
  • Zimmer C., Luck G., Fritzsche H., Triebel H. DNA-copper(II) complex and the DNA conformation. Biopolymers 1971; 10: 441–463
  • Pezzano H., Podo F. Structure of binary complexes of mono- and polynucleotides with metal ions of the first transition group. Chemical Reviews 1980; 80: 365–401
  • Tajmir-Riahi H.A., Langlais M., Savoie R. A laser Raman spectroscopic study of the interaction of calf thymus DNA with Cu(II) and Pb(II) ions: metal ion binding and DNA conformational changes. Nucleic Acids Research 1988; 16: 751–762
  • Kornilova S.V., Blagoi Y.P., Moskalenko LP., Nikiforova N.A., Gladchenko N.A. Effect of metal ions on DNA conformation and their biological action on genetic structures of cells. Studia Biophysica 1988; 123: 77–84
  • Aronovitch J., Godinger D., Samuni A., Czapski G. Ascorbic acid oxidation and DNA scission catalyzed by iron and copper chelates. Free Radical Research Communications 1987; 2: 241–258
  • Rahman A., Hadi S.M., Parish J.H., Ainly K. Strand scission in DNA induced by quercetin and Cu(H): role of Cu(I) and oxygen free radicals. Carcinogenesis 1989; 10: 1833–1839
  • Ehrenfeld G.M., Shipley J.B., Heimbrook D.C., Sugiyama H., Long E.C., van Boom J.H., van der Marel G.A., Oppenheimer N.J., Hecht S.M. Copper-dependent cleavage of DNA by bleomycin. Biochemistry 1987; 26: 931–942
  • Halliwell B., Gutteridge J.M.C. Oxygen toxicity, oxygen radicals, transition metals and disease. Biochemical Journal 1984; 219: 1–14
  • Meneghini R. Genotoxicity of active oxygen species in mammalian cells. Mutation Research 1988; 195: 215–230
  • Hutchinson F. Chemical changes in DNA by ionizing radiation. Progress in Nucleic Acid Research and Molecular Biology 1985; 32: 115–155
  • Aebi H. Catalase in vitro. Methods in Enzymology 1984; 105: 121–126
  • Petering D.H., Antholine W.E. Copper toxicity: speciation and reactions of copper in biological systems. Reviews in Biochemical Toxicology 1988; 9: 225–270
  • Kumar K.S., Rowse C., Hochstein P. Copper-induced generation of superoxide in human red cell membrane. Biochemical and Biophysical Research Communications 1978; 83: 587–592
  • Chevion M. A site-specific mechanism for free radical induced biological damage: the essential role of redox active transition metals. Free Radicals in Biology and Medicine 1988; 5: 27–37
  • Davison A.J., Kettle A.J., Fatur D.J. Mechanism of inhibition of catalase by ascorbate. The Journal of Biological Chemistry 1986; 261: 1193–1200
  • Chiou S.-H. DNA- and protein-scission activities of ascorbate in the presence of copper ion and a copper peptide complex. Journal of Biochemistry 1983; 94: 1259–1267
  • Kochi J.K. Organometallic mechanisms and catalysis. Academic Press, New York, San Francisco and London 1978; 99–106
  • Metzger J.O. Herstellung (Erzeugung) von Radikalen. Methoden der organischen Chemie (Houben-Weyl), M. Regitz, G. Giese. Thieme, Stuttgart 1989; vol. E10a: 143

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