Extracellular-Superoxide Dismutase Type C (EC-SOD C) Reduces Myocardial Damage in Rats Subjected to Coronary Occlusion and 24 Hours of Reperfusion

References

• Werns S. W., Simpson P. J., Mickelson J. K., Shea M. J., Pitt B., Lucchesi B. R. Sustained limitation by superoxide dismutase of canine myocardial injury due to regional ischemia followed by reperfusion. Journal of Cardiovascular Pharmacology 1988; 11: 36–44
   PubMed Web of Science ®Google Scholar
• Burton K. P. Evidence of direct toxic effects of free radicals on the myocardium. Free Radical Biology Medicine 1988; 4: 15–24
   PubMed Web of Science ®Google Scholar
• Ytrehus K., Gunnes S., Myklebust R., Mjøs O. D. Protection by superoxide dismutase and catalase in the isolated rat heart reperfused after prolonged cardioplegia: a combined study of metabolic, functional and morphometric ultrastructural variables. Cardiovascular Research 1987; 21: 492–499
   PubMed Web of Science ®Google Scholar
• Ambrosio G., Becker L. C., Hutchin G. M., Weisman H. F., Weisfelt M. L. Reduction in experimental infarct size by recombinant human superoxide dismutase; insights into the pathophysiology of reperfusion injury. Circulation 1986; 6: 1424–1433
   Google Scholar
• Burton K. P. Superoxide dismutase enhances recovery following myocardial ischemia. American Journal of Physiology 1985; 248: H637–643
   PubMedGoogle Scholar
• Jolly S. R., Kane W. J., Bailie M. B., Abrams G. D., Lucchesi B. R. Canine myocardial reperfusion injury: its reduction by the combined administration of superoxide dismutase and catalase. Circulation Research 1984; 54: 277–285
   PubMed Web of Science ®Google Scholar
• Engler R., Gilpin E. Can superoxide dismutase alter infarct size?. Circulation 1989; 79: 1137–1142
   PubMed Web of Science ®Google Scholar
• Ferrari R., Ceconi C., Curello S., Ghielmi S., Albertini A. Superoxide dismutase: Possible therapeutic use in cardiovascular disease. Pharmacological Research Communications 1989; 21(suppl 2)57–65
   Google Scholar
• Kloner R. A., Przyklenk K., Whittaker P. Deleterious effects of oxygen radicals in ischemia/reperfusion. Circulation 1989; 80: 1115–1127
   PubMed Web of Science ®Google Scholar
• Gallagher K. P., Buda A. J., Pace D., Gerren R. A., Shlafer M. Failure of superoxide dimutase and catalase to alter size of infarction in conscious dogs after 3 hours of occlusion followed by reperfusion. Circulation 1986; 73: 1065–1076
   PubMed Web of Science ®Google Scholar
• Miura T., Downey J. G., Hotta D., Imura O. Effects of superoxide dismutase plus catalase on myocardial infarct size in rabbits. Canadian Journal of Cardiology 1988; 4: 407–411
   PubMed Web of Science ®Google Scholar
• Odlind B., L-Appelgren E., Bayati A., Wolgast M. Tissue distribution of 125I-labelled bovine superoxide dismutase (SOD) in the rat. Pharmacology and Toxicology 1988; 62: 95–100
   PubMedGoogle Scholar
• Marklund S. L. Human copper-containing superoxide dismutase of high molecular weight. Proceedings of the National Academy of Sciences of the United States of America 1982; 79: 7634–7638
   PubMed Web of Science ®Google Scholar
• Tibell L., Hjalmarsson K., Edlund T., Skogman G., Ængstr R., ömMarklund S. L. Expression of human extracellular-superoxide dismutase in Chinese hamster ovary cells and characterization of the product. Proceedings of the National Academy of Sciences of the United States of America 1987; 84: 6634, 6638
   PubMed Web of Science ®Google Scholar
• Karlsson K., Marklund S. L. Plasma clearance of human extracellular-superoxide dismutase C in rabbits. Journal of Clinical Investigation 1988; 82: 762–786
   PubMed Web of Science ®Google Scholar
• Marklund S. L., Karlsson K. Binding of human extracellular-superoxide dismutase C to cultured cell lines and to blood cells. Laboratory Investigation 1989; 60: 659–666
   PubMed Web of Science ®Google Scholar
• Aoki N., Bitterman H., Brezinski M. E., Lefer A. M. Cardioprotective actions of human superoxide dismutase in two reperfusion models of myocardial ischaemia in the rat. British Journal of Pharmacology 1988; 95: 735–740
   PubMed Web of Science ®Google Scholar
• Omar B. A., Gad N. M., Jordan M. C., Striplin S. P., Russel W. J., Downey J. M., McCord J. M. Cardioprotection by CuZn-superoxide dismutase is lost at high doses in the reoxygenated heart. Free Radical Biology and Medicine 1990; 9: 465–471
   PubMed Web of Science ®Google Scholar
• Schaper W. Experimental infarcts and the microcirculation. Therapeutic Approaches to Myocardial Infarct Size Limitation, D. J. Hearse, D. M. Yellon. Raven Press, New York 1984; 79–90
   Google Scholar
• Hock C. E., Ribeiro L. G.T., Lefer A. M. Preservation of ischemic myocardium by a new converting enzyme inhibitor, enalaprilic acid, in acute myocardial infarction. American Heart Journal 1985; 109: 222–228
   PubMed Web of Science ®Google Scholar
• Marklund S. L. Direct assay with potassium superoxide. CRC-Handbook of Methods for Oxygen Radical Research, R. A. Greenwald. CRC Press, Boca Raton, Florida 1985; 249–255
   Google Scholar
• McCord J. M., Fridovich I. Superoxide dismutase, an enzymic function for eryhtrocuprein. Journal of Biological Chemistry 1969; 244: 6049–6055
   PubMed Web of Science ®Google Scholar
• Kramer J. H., Arroyo C. M., Dickens B. F., Weglicki W. B. Spin trapping evidence that graded myocardial ischemia alters post-ischemic superoxide production. Free Radical Biology Medicine 1987; 3: 153–159
   PubMed Web of Science ®Google Scholar
• Johansson M. H., Deinum J., Marklund S. L., P-Sjöquist O. Recombinant human extracellular superoxide dismutase reduces concentration of oxygen free radicals in the reperfused rat heart. Cardiovascular Research 1990; 24: 500–503
   PubMed Web of Science ®Google Scholar
• Bolli R., Jeroudi M. O., Patel B. S., DuBose C. M., Lai E. K., Robert R., McCay P. B. Direct evidence that oxygen-derived free radicals contribute to postischemic myocardial dysfunction in the intact dog. Proceedings of the National Academy of Sciences of the United States of America 1989; 86: 4695–4699
   PubMed Web of Science ®Google Scholar
• Downey J. M., Hearse D. J., Yellon D. M. The role of xanthine oxidase during myocardial ischemia in several species including man. Journal of Molecular and Cellular Cardiology 1988; 20(suppl 2)55–63
   PubMedGoogle Scholar
• Lucchesi B. R., Werns S. W., Fantone J. C. The role of the neutrophil and free radicals in ischemic myocardial injury. Journal of Molecular and Cellular Cardiology 1989; 21: 1241–1251
   PubMed Web of Science ®Google Scholar
• Suzuki M., Inauen W., Kvietys P., Grisham M. B., Meninger C., Schelling M. E., Granger H. J., Granger D. N. Superoxide mediates reperfusion-induced leukocyte-endothelial cell interactions. American Journal of Physiology 1989; 257: H1740–1745
   PubMed Web of Science ®Google Scholar
• Grisham M. B., Hernandez L. A., Granger N. Xanthine oxidase and neutrophil infiltration in intestinal ischemia. American Journal of Physiology 1986; 14: G567–G574
   Google Scholar
• Nakazawa H., Ban K., Ichimori K., Minezaki K., Okino H., Masuda T., Aoki N., Hori S. The link between free radicals and myocardial injury. Japanese Circulation Journal 1988; 52: 645–654
   Google Scholar
• Werns S. W., Shea M. J., Driscoll E. M., Cohen C., Abrams G. D., Pitt B., Lucchesi B. R. The independent effects of oxygen radical scavengers on canine infarct size: Reduction by superoxide dismutase but not catalase. Circulation Research 1985; 56: 895–898
   PubMed Web of Science ®Google Scholar
• Chambers D. E., Parks D. A., Patterson G., Roy R., McCord J. M., Yoshida S., Parmley L. F., Downey J. M. Xanthine oxidase as a source of free radical damage in myocardial ischemia. Journal of Molecular and Cellular Cardiology 1985; 17: 145–152
   PubMed Web of Science ®Google Scholar
• Hatori N., Miyazaki A., Tadokoro H., Rydén L., Moll J., Rajagopalan R. E., Fishbein M. C., Meerbaum S., Corday E., Drury J. K. Beneficial effects of coronary venous retroinfusion of superoxide dismutase and catalase on reperfusion arrhythmias, myocardial function and infarct size in dogs. Journal of Cardiovascular Pharmacology 1989; 14: 396–404
   PubMed Web of Science ®Google Scholar
• Przyklenk K., Kloner R. A. Reperfusion injury by oxygen-derived free radicals: Effect of superoxide dismutase plus catalase, given at the time of reperfusion, on myocardial infarct size contractile function coronary microvasculature and regional myocardial blood flow. Circulation Research 1989; 64: 86–96
   PubMed Web of Science ®Google Scholar
• Downey J. M., Miura T., Eddy J. L., Chambers D. E., Mellert T., Hearse D. J., Yellon D. M. Xanthine oxidase is not a source of free radicals in the ischemic rabbit heart. Journal of Molecular Cellular Cardiology 1987; 19: 1053–1060
   PubMed Web of Science ®Google Scholar
• Patel B. S., Jeroudi M. O., O'Neill P. G., Robert R., Bolli R. Effect of human recombinant superoxide dismutase on canine myocardial infarction. American Journal of Physiology 1990; 258: H369–H380
   PubMedGoogle Scholar
• Uraizee A., Reimer K. A., Murry C. E., Jennings R. B. Failure of superoxide dismutase to limit size of myocardial infarction after 40 minutes of ischemia and 4 days of reperfusion in dogs. Circulation 1987; 75: 1237–1248
   PubMed Web of Science ®Google Scholar
• Gallagher K. P., Buda A. J., Pace D., Gerren R. A., Shlafer M. Failure of superoxide dismutase and catalase to alter size of infarction in conscious dogs after 3 hours of occlusion followed by reperfusion. Circulation 1986; 73: 1065–1076
   PubMed Web of Science ®Google Scholar
• Richard V. J., Murry C. E., Jennings R. B., Reimer K. A. Therapy to reduce free radicals during early reperfusion does not limit the size of myocardial infarcts caused by 90 minutes of ischemia in dogs. Circulation 1988; 78: 473–480
   PubMed Web of Science ®Google Scholar
• Tamura Y., Chi L., Driscoll E. M., Hoff P. T., Freeman B. A., Gallagher K. P., Lucchesi B. R. Superoxide dismutase conjugated to polyethylene glycol provides sustained protection against myocardialischemia/reperfusion injury in canine heart. Circulation Research 1988; 63: 944–959
   PubMed Web of Science ®Google Scholar
• Tanaka M., Stoler R. C., Fitz Harris G. P., Jennings R. B., Reimer K. A. Evidence against the “early protection-delayed death” hypothesis of superoxide dismutase therapy in experimental myocardial infarction – Polyethylene glycol-superoxide dismutase plus catalase does not limit myocardial infarct size in dogs. Circulation Research 1990; 67: 636–644
   PubMed Web of Science ®Google Scholar
• P-Sjöquist O., Carlsson L., Jonasson G., Marklund S. L., Abrahamsson T. Cardioprotective effects of recombinant human extracellular-superoxide dismutase type C in rat isolated heart subjected to ischemia and reperfusion. Journal of Cardiovascular Pharmacology 1991; 17: 678–683
   PubMed Web of Science ®Google Scholar
• Erlansson M., Bergqvist D., Marklund S. L., Persson N. H., Svensjö E. Superoxide dismutase as an inhibitor of postischemic microvascular permeability increase in the hamster. Free Radical Biology Medicine 1990; 9: 59–65
   PubMed Web of Science ®Google Scholar
• P-Sjöquist O., Marklund S. L. Endothelium bound extracellular superoxide dismutase type C reduces damage in reperfused ischaemic rat hearts. Cardiovascular Research 1992; 26: 347–350
   PubMed Web of Science ®Google Scholar
• Hale S. H., Vivaldi M. T., Kloner R. A. Fluorescent microspheres: a new tool for visualization of ischemic myocardium in rats. American Journal of Physiology 1986; 20: H863–H868
   Google Scholar