24
Views
23
CrossRef citations to date
0
Altmetric
Original Article

Induction of Granulocytic Maturation in HL-60 Human Leukemia Cells by Free Radicals: A Hypothesis of Cell Differentiation Involving Hydroxyl Radicals

, , &
Pages 1-15 | Received 15 Feb 1993, Published online: 07 Jul 2009

References

  • Collins S. J., Gallo R. C., Gallagher R. E. Continuous growth and differentiation of human myeloid leukemic cells in suspension culture. Nature 1977; 270: 347–349
  • Gallagher R., Collins S., Trujillo J., McCredie K., Ahearn M., Tsai S., Metzgar R., Aulakh G., Ting R., Ruscetti F., Gallo R. C. Characterization of the continuous, differentiating myeloid cell line (HL-60) from a patient with acute promyelocytic leukemia. Blood 1979; 54: 713–733
  • Collins S. J., Ruscetti F. W., Gallagher R. E., Gallo R. C. Terminal differentiation of human promyelocytic leukemia cells induced by dimethylsulfoxide and other polar compounds. Proceedings of the National Academy of Sciences, USA 1978; 75: 2458–2462
  • Collins S. J., Ruscetti F. W., Gallagher R. E., Gallo R. C. Normal functional characteristics of cultured human promyelocytic leukemia cells (HL-60) after induction of differentiation by DMSO. Journal of Experimental Medicine 1979; 149: 969–974
  • Blair O. C., Carbone R., Sartorelli A. C. Differentiation of HL-60 promyelocytic leukemia cells: Simultaneous determination of phagocytic activity and cell cycle distribution by flow cytometry. Cytometry 1986; 7: 171–177
  • Ross D. W. Measurement of myeloid maturation by flow cytochemistry in HL-60 leukemia: Esterase is inducible, myeloperoxidase is not. Cytochemistry 1986; 7: 263–267
  • Wersto R. P., Herz F., Gallagher R. E., Koss L. G. Cell cycle-dependent reactivity with the monoclonal antibody Ki-67 during myeloid cell differentiation. Experimental Cell Research 1988; 179: 79–88
  • Huberman E., Callaham M. F. Induction of terminal differentiation in human promyelocytic leukemia cells induced by tumor promoting agents. Proceedings of the National Academy of Sciences, USA 1979; 76: 1293–1297
  • Rovera G., Santoli D., Damsky C. Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol ester. Proceedings of the National Academy of Sciences, USA 1979; 76: 2779–2783
  • Rovera G., Ferrero D., Pagliardi G. L., Vartikar J., Pessano S., Bottero L., Abraham S., Lebman D. Induction of differentiation of human myeloid leukemias by phorbol diesters: phenotypic changes and mode of action. Annals of the New York Academy of Sciences 1982; 397: 211–220
  • Lotem J., Sachs L. Regulation of normal differentiation in mouse and human myeloid leukemic cells by phorbol esters and the mechanism of tumor promotion. Proceedings of the National Academy of Sciences, USA 1979; 76: 5158–5162
  • Breitman T. R., Selonick S. E., Collins S. J. Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid. Proceedings of the National Academy of Sciences 1980; 77: 2936–2940
  • Barker K. A., Newburger P. E. Relationships between the cell cycle and the expression of c-myc and transferrin receptor genes during induced myeloid differentiation. Experimental Cell Research 1990; 186: 1–5
  • Bodner A. J., Ting R. C., Gallo R. C. Induction of differentiation of human promyelocytic leukemia cells (HL-60) by nucleosides and methotrexate. Journal of the National Cancer Institute 1981; 67: 1025–1030
  • Tasaka K., Nakaya N., Nonaka T. Effects of histamine, granulocyte colony-stimulating factor and db-cAMP on the differentiation of HL-60 cells. Agents and Actions 1990; 30: 240–243
  • Miyaura C., Abe E., Kuribayashi T., Tanaka H., Konno K., Nishii Y., Suda T. 1α,25-Dihydroxyvitamin D3 induces differentiation of human myeloid leukemia cells. Biochemical and Biophysical Research Communications 1981; 102: 937–943
  • Tanaka H., Abe E., Miyaura C., Kuribayashi T., Nishii Y., Suda T. 1,25-dihydroxychole-calciferol and a human myeloid leukemia line (HL-60); the presence of a cytosol receptor and induction of differentiation. Biochemical Journal 1982; 204: 713–719
  • Tanaka H., Abe E., Miyaura C., Shina Y., Suda T. 1,25-Dihydroxyvitamin D3 induces differentiation of human promyelocytic leukemia cells (HL-60) into monocyte-macrophages but not into granulocytes. Biochemical and Biophysical Research Communications 1983; 117: 86–92
  • McCarthy D. M., San Miguel J. F., Freake H. C., Green P. M., Zola H., Catovsky D., Goldman J. M. 1,25-Dihydroxyvitamin D3 inhibits proliferation of human promyelocytic leukemia (HL-60) cells and induces monocyte macrophage differentiation in HL-60 and normal human bone marrow cells. Leukemia Research 1983; 7: 51–55
  • Schwartz E. L., Sartorelli A. C. Structure-activity relationships for the induction of differentiation of HL-60 human acute promyelocytic leukemia cells by anthracyclines. Cancer Research 1982; 42: 2651–2655
  • Morin M. J., Sartorelli A. C. Inhibition of glycoprotein biosynthesis by the inducers of HL-60 cell differentiation, aclacinomycin A and marcellomycin. Cancer Research 1984; 44: 2807–2812
  • Schwartz E. L., Blair O. C., Sartorelli A. C. Cell cycle events associated with the termination of proliferation by cytotoxic and differentiation-inducing actions of 6-thioguanine on HL-60 cells. Cancer Research 1984; 44: 3907–3910
  • Ball E. D., Guyre P. M., Shen L., Glynn M., Maliszewski C. R., Baker P. E., Fanger M. W. Gamma interferon induces monocytoid differentiation in the HL-60 cell line. Journal of Clinical Investigations 1984; 73: 1072–1077
  • Speier Ch., Newburger P. E. Changes in superoxide dismutase, catalase and the glutathione cycle during induced myeloid differentiation. Archives of Biochemistry and Biophysics 1986; 251: 551–557
  • C-Yeh J. G., Papamicheal M., Faulk W. P. Loss of transferrin receptors following induced differentiation of HL-60 promyelocytic leukemia cells. Experimental Cell Research 1982; 138: 429–433
  • Mendelsohn N., Gilbert H. S., Christman J. K., Ács G. Effect of maturation on the response of human promyelocytic leukemia cells (HL-60) to the tumor promoter 12-O-tetradecanoylphorbol-13-acetate. Cancer Research 1980; 40: 1469–1474
  • Harris P., Ralph P. Human leukemic models of myelomonocytic development: A review of HL-60 and U937 cell lines. Journal of Leukocyte Biology 1985; 37: 407–422
  • Thompson B. Y., Sivam G., Britigan B. E., Rosen G. M., Cohen M. S. Oxygen metabolism of the HL-60 cell line: Comparison of the effects of monocytoid and neutrophilic differentiation. Journal of Leukocyte Biology 1988; 43: 140–147
  • May W. S., Jacobs S., Cuatrecasas P. Association of phorbol ester-induced hyper-phosphorylation and reversible regulation of transferrin membrane receptors in HL-60 cells. Proceedings of the National Academy of Sciences, USA 1984; 81: 2016–2020
  • Pelicci P. G., Testa U., Thomopoulos P., Tabilio A., Vainchenka W., Titeux M., Gourdin M. F., Rochant H. Inhibition of transferrin binding and iron uptake of hematopoietic cell lines by phorbol esters. Leukemia Research 1984; 8: 597–609
  • Ho P. T.C., Ishiguro K., Sartorelli A. C. Regulation of transferrin receptor in myeloid and monocytic differentiation of HL-60 leukemia cells. Cancer Research 1989; 49: 1989–1995
  • Trayner I. D., Clemens M. J. Phorbol ester-induced macrophage-like differentiation of human promyelocytic leukemia (HL-60) cells occurs independently of transferrin availability. Cancer Research 1990; 50: 7221–7225
  • Oberley L. W., Oberley T. D. Free radicals, cancer and aging. Free Radicals, Aging, and Degenerative Diseases, J. E. Johnson, R. Walford, D. Harman, J. Miquel. Alan R. Liss, New York 1986; 325–371
  • Oberley L. W., Ridnour L. R., Sierra-Rivera E., Oberley T. D., Guernsey D. L. Superoxide dismutase activities of differentiating clones from an immortal cell line. Journal of Cellular Physiology 1989; 138: 50–60
  • Sohal R. S., Allen R. G. Oxidative stress as a causal factor in differentiation and aging: a unifying hypothesis. Experimental Gerontology 1990; 25: 499–522
  • Saito H., Kuroki T., Nose K. Decrease in CuZn-superoxide dismutase mRNA level during differentiation of human monocytic and promyelocytic leukemia cells. Federation of European Biochemical Societies (FEBS) Letters 1989; 249: 253–256
  • Auwerx J. H., Chait A., Wolfbauer G., Deeb S. S. Loss of Copper-Zinc superoxide dismutase gene expression in differentiated cells of myelo-monocytic origin. Blood 1989; 74: 1807–1810
  • Zs-Nagy I. The horizons of an interdisciplinary synthesis in experimental gerontology. Archives of Gerontology and Geriatrics 1991; 12: 329–349
  • Zs-Nagy I. A proposal for reconsideration of the role of oxygen free radicals in cell differentiation and aging. Annals of the New York Academy of Sciences 1992; 673: 142–148
  • Walling C. Fenton's reagent revisited. Accounts of Chemical Research 1975; 8: 125–131
  • Czapski G. On the use of OH scavengers in biological systems. Israel Journal of Chemistry 1984; 24: 29–32
  • Zs-Nagy I. Functional consequences of free radical damage to cell membranes. CRC Handbook of Free Radicals and Antioxidants in Biomedicine, J. Miquel, A. T. Quintanilha, H. Weber. CRC Press, Boca Raton, Florida 1989; Vol. I: 199–207
  • Floyd R. A. Role of oxygen free radicals in carcinogenesis and brain ischemia. Federation of American Societies for Experimental Biology (FASEB) Journal 1990; 4: 2587–2597
  • Fenton H. J.H. Oxidation of tartaric acid in presence of iron. Journal of Chemical Society 1894; 65: 899–910
  • Zs-Nagy I., Floyd R. A. Hydroxyl free radical reactions with amino acids and proteins studied by electron spin resonance spectroscopy and spin trapping. Biochimica et Biophysica Acta 1984; 790: 238–250
  • Floyd R. A., Zs-Nagy I. Formation of long-lived hydroxyl free radical adducts of proline and hydroxyproline in a Fenton reaction. Biochimica et Biophysica Acta 1984; 790: 94–97
  • Nagy K., Pásti G., Bene L., Zs-Nagy I. Induction of erythroid differentiation of K562 human leukemia cells by OH free radicals generated through Fenton reaction under physiological conditions in vitro. 1993, (submitted)
  • Lozzio C. B., Lozzio B. B. Human chronic myelogenous leukemia cell line with positive Philadelphia chromosome. Blood 1975; 45: 321–334
  • Floyd R. A., Lewis C. A. Hydroxyl free radical formation from hydrogen peroxide by ferrous iron-nucleotide complexes. Biochemistry 1983; 22: 2645–2649
  • Becton D. L., Roberts B. Antileukemic effects of deferoxamine on human myeloid leukemia cell lines. Cancer Research 1989; 49: 4809–4812
  • Mizuhashi F., Murata K., Kitagaki T., Nezu M., Sano M., Tomita I. Antitumor activities of IKP-104, a 4(1H)-pyrizinone derivative, on cultured and implanted tumors. Japanese Journal of Cancer Research 1990; 81: 1300–1306
  • Markwell M. A.K., Haas S. M., Bieber L. L., Tolbert N. E. A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. Analytical Biochemistry 1978; 87: 206–210
  • Flohé L., Ötting F. Superoxide dismutase assays. Methods in Enzymology 1984; 105: 93–104
  • Gaunt G. L., De Duve C. Subcellular distribution of D-amino acid oxidase and catalase in rat brain. Journal of Neuro-chemistry 1976; 26: 749–759
  • Gutteridge J. M.C., Zs-Nagy I., Maidt L., Floyd R. A. ADP-iron as a Fenton reactant: radical reactions detected by spin trapping, hydrogen abstraction and aromatic hydroxylation. Archives of Biochemistry and Biophysics 1990; 277: 422–428
  • Rush J. D., Maskos Z., Koppenol W. H. Reactions of iron(II) nucleotide complexes with hydrogen peroxide. Federation of European Biochemical Societies (FEBS) Letters 1990; 261: 121–123
  • Haber F., Weiss J. The catalytic decomposition of hydrogen peroxide by iron salts. Proceedings of the Royal Society of London 1934; 147: 332–351
  • Bridges K. R., Hoffman K. E. The effect of ascorbic acid on the intracellular metabolism of iron and ferritin. Journal of Biological Chemistry 1986; 261: 14273–14277
  • Jonas S. K., Riley P. A., Willson R. L. Hydrogen peroxide cytotoxicity. Low-temperature enhancement by ascorbate or reduced lipoate. Biochemical Journal 1989; 264: 651–655
  • Klug D., Rabani J., Fridovich I. A direct demonstration of the catalytic action of superoxide dismutase through the use of pulse radiolysis. Journal of Biological Chemistry 1972; 247: 4839–4842
  • McAdam M. E., Fox R. A., Lavelle F., Fielden M. A pulse radiolysis study of the manganese-containing superoxide dismutase from Bacillus stearothermophilus. A kinetic model for the enzyme action. Biochemical Journal 1977; 165: 71–79
  • McAdam M. E., Lavelle F., Fox R. A., Fielden M. A pulse radiolysis study of the manganese-containing superoxide dismutase from Bacillus stearothermophilus. Further studies on the properties of the enzyme. Biochemical Journal 1977; 165: 81–87
  • Halliwell B., Gutteridge J. M.C. Oxygen free radicals and iron in relation to biology and medicine: Some problems and concepts. Archives of Biochemistry and Biophysics 1986; 246: 501–514
  • Saran M., Bors W. Oxygen radicals acting as chemical messengers: hypothesis. Free Radical Research Communications 1989; 7: 213–220
  • Schreck R., Bauerle P. A. A role for oxygen radicals as second messengers. Trends in Cell Biology 1991; 1: 39–42

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.