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Original Article

Linear and Non Linear Competition Plots in the Deoxyribose Assay for Determination of Rate Constants for Reaction of non Steroidal Antiinflammatory Drugs with Hydroxyl Radicals

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Pages 571-579 | Received 16 Jan 1995, Published online: 07 Jul 2009

References

  • Vapaatalo H. Free radicals and antiinflammatory drugs. Medical Biology 1986; 64: 1–7
  • Farber J. H., Kyle M. E., Coleman J. B. Biology of diseases, mechanisms of cell injury by activated oxygen species. Laboratory Investigation 1990; 62, 670M579
  • Blake D. R., Hall N. D., Treby D. A., Halliwell B., Gutteridge J. M.C. Protection against superoxide and hydrogen peroxide in synovial fluid from rheumatoid patients. Clinical Science 1981; 61: 483–486
  • Minta J. O., Williams D. Some nonsteroidal antiinflammatory drugs inhibit the generation of superoxide anions by activated polymorphs by blocking ligand-receptor interactions. Journal of Rheumatology 1985; 12: 751–757
  • Halliwell B., Gutteridge J. M.C. Free radicals in biology andmedicine. 2nd edition. Clarendon Press, Oxford 1989
  • Halliwell B., Gutteridge J. M.C., Aruoma O. I. The deoxyribose method: a simple test tube assay for determination of the rate constants for reactions of hydroxyl radicals. Analytical Biochemistry 1987; 165: 215–219
  • Aruoma O. I. Deoxyribose assay for detecting hydroxyl radicals. Methods in Enzymology 1994; 233: 57–66
  • Laughton M. J., Halliwell B., Evans P. J., Hoult J. R.S. Antioxidant and pro-oxidant actions of the plant phenolics quercetin, gossipol and myricetin. Biochemical Pharmacology 1989; 38: 2859–2865
  • Aruoma O. I., Evans P. J., Kaur H., Sutcliffe L., Halliwell B. An evaluation of the antioxidant and potential pro-oxidant properties of food additives and Trolox C, vitamin E and probucol. Free Radical Research Communications 1990; 10: 143–157
  • Aruoma O. I., Halliwell B., Aeschbach R., Löligers J. Antioxidant and pro-oxidant properties of active rosemary constituents: carnosol and carnosic acid. Xenobiotica 1992; 22: 257–268
  • Aruoma O. I., Halliwell B. The iron binding and hydroxyl radical scavenging action of anti-inflammatory drugs. Xenobiotica 1988; 18: 459–470
  • Winterbourn C. Factors that influence the deoxyribose oxidation assay for Fenton reaction products. Free Radical Biology and Medicine 1991; 11: 353–360
  • Aruoma O. I., Grootveld M., Halliwell B. The role of iron in ascorbate-dependent deoxyribose degradation. Evidence with a site-specific hydroxyl radical generation caused by iron ions bound to the deoxyribose molecule. Journal of Inorganic Biochemistry 1987; 29: 289–299
  • Aruoma O. I., Chaudhary S. S., Grootveld M., Halliwell B. Binding of iron (II) ions to the pentose sugar 2-Deoxyribose. Journal of Inorganic Biochemistry 1989; 35: 149–155
  • Cheeseman K. H., Beavis A., Esterbauer H. Hydroxyl-radical-induced iron-catalysed degradation of 2-deoxyribose. Quantitative determination of malondialdehyde. Biochemical Journal 1988; 252: 649–653
  • Halliwell B., Gutteridge J. M.C. Formation of a thiobarbituric-acid-reactive substance from deoxyribose in the presence of iron salts. The role of superoxide and hydroxyl radicals. FEBS Letters 1981; 128: 347–352
  • Gutteridge J. M.C. Reactivity of hydroxyl and hydroxyl-like radicals discreminated by release of thiobarbituric acid-reactive material from deoxy sugars, nucleosides and benzoate. Biochemical Journal 1984; 224: 761–767
  • Zhao M. J., Jung L., Tanelian C., Mechin R. Kinetics of the competitive degradation of deoxyribose and other biomolecules by hydroxyl radicals produced by the Fenton reaction. Free Radical Research 1994; 20: 345–363
  • Aruoma O. I., Murcia A., Butler J., Halliwell B. Evaluation of the antioxidant and prooxidant actions of gallic acid and its derivates. Journal of Agriculture and Food Chemistry 1993; 41: 1880–1885

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