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Original Article

Failure of Electron Paramagnetic Resonance Spectroscopy Studies to Detect Elevated Free Radical Signals in Liver Biopsy Specimens from Patients with Alcoholic Liver Disease

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Pages 99-107 | Received 09 Jun 1994, Published online: 07 Jul 2009

References

  • Barry R., McGivan J. Acetaldehyde alone may initiate hepatocellular damage in acute alcoholic liver disease. Gut 1985; 26: 1065–1069
  • French S., Burbige E., Tarder G. Lymphocyte sequestration by the liver in alcoholic hepatitis. Archives of Patholoy and Laboratory Medicine 1979; 103: 146–152
  • Lieber C. Alcohol, protein metabolism and liver injury. Gastroenterology 1980; 79: 373–390
  • Winston G., Cederbaum A. NADPH production of oxy radicals by purified components of the rat liver mixed-function oxidase system. Role in microsomal oxidation of ethanol. Journal of Biological Chemistry 1983; 258: 1514–1519
  • Ohnishi K., Lieber C. Respective role of superoxide and hydroxyl radical in the activity of the reconstituted microsomal ethanol oxidising system. Archives of Biochemistry and Biophysics 1978; 91: 798–803
  • Cederbaum A., Dicker E., Cohen G. Effect of hydroxyl radical scavengers on microsomal oxidation of alcohols and on associated microsomal reactions. Biochemistry 1978; 17: 3058–3064
  • Wolff S., Garner A., Dean R. Protein denaturation by hydrogen peroxid. Trends in Biochemical Sciences 1986; 11: 27–31
  • Ward J., Evans J., Limoli C., Calabro-Jones P. Radiation and hydrogen peroxide induced free radical damage to DNA. British Journal of Cancer 1987; 55S8: 105–112
  • Klein S., Lieber C. Increased microsomal oxidation of hydroxyl radical scavenging agents and ethanol after chronic consumption of ethanol. Archives of Biochemistry and Biophysics 1983; 273: 425–43
  • Iversen S., Dormandy T. Identification of a diene conjugated component of human lipid as octadeca-9,11 dienoic acid. Federation of European Biochemical Societies Letters 1984; 171/2: 320–324
  • Fink R., Marjot D., Cawood P., Iversen S., Clemens M., Patsalos, Norden A., Dormandy T. Increased free radical activity in alcoholics. Lancet 1985; Aug: 291–294
  • Yamazaki I. Free radicals in Biology, W. Pryor. Academic Press, New York 1987; 183–218
  • Slater T. Free radical mechanisms in tissue injury. Pion Ltd., London 1972
  • Symons M. C.R. Chemical and biochemical aspects of ESR spectroscopy. Van Nostrand Reinhold, Wokingham 1978
  • Borg D. Free radicals in biology, W. Pryor. Academic Press, New York 1976
  • Iversen S., Cawood P., Dormandy T. A method for the measurement of a diene-conjugated derivative of linoleic acid, 18:2(9, 11), in serum phospholipid, and possible origins. Annals of Clinical Biochemistry 1985; 22: 137–140
  • Dodd N. Some EPR signals in tumour tissue. British Journal of Cancer 1973; 28: 257–262
  • Elek G., Rockenbauer A., Jokay L. A study of free radicals in paraffin embedded and deparaffinized human heart muscle tissue using electron spin resonance. Histochemistry 1987; 87: 499–504
  • Ambari L., Hung J., Edelstein L., Van Woerst M. Quantification of melanin in cardiac and hepatic lipofuscin. Experieenta 1977; 33: 296–298
  • Knecht K., Bradford B., Mason R., Thurman R. In vivo formation of a free radical metabolite of ethanol. Molecular Pharmacology 1990; 38: 26–30
  • Reinke L., Rau J., McCay P. Possible roles of free radicals in alcoholic tissue damage. Free Radical Research Communications 1990; 9: 205–211
  • McCay P. B., Reinke L. A., Rau J. M. Hydroxyl radicals are genera ed by hepatic microsomes during NADPH oxidation: relationship to ethanol metabolism. Free Radical Research Communications 1992; 15(6): 335–346
  • Knecht K. T., Thurman R. G., Mason R. P. Role of superoxide and trace transition metals in the production of alpha-hydroxyethyl radical from ethanol by microsomes from alcohol dehydrogenase-deficient deermice. Archives of Biochemistry and Biophysics 1993; 303: 339–348
  • Taiwo F. A., Symons M. C.R. Interaction of ethanol with haemoglobin: implications for alcohol abuse. Free Radical Research Communications 1993; 19(2): 121–4
  • Butcher G. P., Deighton N., Batt R. M., Ding B., Haywood S., Hoffman J., Jackson M. J., Symons M. C.R., Rhodes J. M. Electron paramagnetic resonance spectroscopy of stable free radicals in the liver compared with ultrastructural and functional damage in a model of alcohol and iron overload. Clinical Science 1993; 84: 339–348
  • Comporti M., Hartman A., Di Luzio N. Effect of in vivo and in vitro ethanol administration on liver lipid peroxidation. Laboratory investigation 1967; 16: 616–624
  • Moscarella S., Laffi G., Coletta D., Arena U., Cappelini A., Gentilini P. Volatile hydrocarbons in the breath of patients with chronic alcoholic liver disease: a possible marker of ethanol-induced lipoperoxidation. Frontiers of gastrointestinal research Vol. 8, P. Gentilini, M. M. Dianzini. P. Rozen Tel Aviv. 1984; 208–216
  • Letteron P., Duchatelle V., Berson A., Fromenty B., Fisch C., Degott C., Benhamou J. P., Pessayre D. Increased ethane exhalation, an in vivo index of lipid peroxidation, in alcohol abusers. Gut 1993; 34: 409–414
  • Wickens D., Davies S., Fairbank J., Tay S., Slater T., Dormandy T. Studies on cervical intraepithelial neoplasia: the level of octadeca-9,11-dienoic acid and measurement of free radical content by electron spin resonance spectroscopy. American Journal of Obstetrics and Gynecology 1990; 162(3): 854–8
  • Britton M., Fong C., Wickens D., Yudkin J. Diet as a source of phopsholipid esterified 9,11-octadecadienoic acid in humans. Clinical Science 1992; 83: 97–101
  • Mazzanti R., Moscarella S., Bensi G., Altavilla E., Gentiline P. Hepatic lipid peroxidation and aldehyde dehydrogenase activity in alcoholic and non-alcoholic liver disease. Alcohol and Alcoholism 1989; 24: 121–128

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