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Original Article

Exogenous Glutathione Attenuates Stunning Following Intermittent Hypoxia in Isolated Rat Hearts

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Pages 115-122 | Received 04 Apr 1995, Accepted 03 Jul 1995, Published online: 07 Jul 2009

References

  • Braunwald E., Kloner R. A. The stunned myocardium: prolonged postischemic ventricular dysfunction. Circulation 1982; 66: 1146–1149
  • Opie L. H. Reperfusion injury and its pharmacologic modification. Circulation 1989; 80: 1049–1062
  • Bolli R. Mechanism of myocardial stunning. Circulation 1990; 82: 723–735
  • Shan X., Aw T. Y., Jones D. P. Glutathione-dependent protection against oxidative injury. Pharmacology Therapeutics 1990; 47: 61–71
  • Curello S., Ceconi C., Bigoli C., Ferrari R., Albertini A., Guamieri C. Changes in the cardiac glutathione status after ischemia and reperfusion. Experientia 1985; 41: 42–43
  • Park Y., Kanekal S., Kehrer J. P. Oxidative changes in hypoxic heart tissue. American Journal of Physiology 1991; 29: H1395–H1405
  • Darley-Usmar V. M., O'Leary V. O., Stone D. The glutathione status of perfused rat hearts subjected to hypoxia and reoxygenation: the oxygen paradox. Free Radical Research Communications 1989; 6: 261–267
  • Lesnefsky E. J., Dauber I. M., Horwitz L. D. Myocardial sulfhydryl pool alterations occur during reperfusion after brief and prolonged myocardial ischemia in vivo. Circulation Research 1991; 68: 605–613
  • Garlick P. B., Davies M. J., Hearse D. J., Slater T. F. Direct detection of free radicals in the reperfused rat heart using electron spin resonance spectroscopy. Circulation Research 1987; 61: 757–760
  • Zweier J. L. Measurement of superoxide-derived free radicals in the reperfused heart. Journal of Biological Chemistry 1988; 263: 1353–1358
  • Blaustein A., Deneke S. M., Stolz R. I., Baxter D., Healey N., Fanburg B. L. Myocardial glutathione depletion impairs recovery after short periods of ischemia. Circulation 1989; 80: 1449–1457
  • Singh A., Lee K. J., Lee C. Y., Goldfarb R. D., Tsan M. Relation between myocardial glutathione content and extent of ischemia/reperfusion injury. Circulation 1989; 80: 1796–1804
  • Tani M. Effects of anti-free radical agents on Na+, Ca+, and function in reperfused rat hearts. American Journal of Physiology 1990; 259: H137–H143
  • Akerboom J. P.M., Sies H. Assay of glutathione, glutathione dissulfide, and gluttathione mixed disulfides in biological samples. Methods of Enzymology 1981; 77: 373–382
  • Tietze F. Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Annals of Biochemistry 1969; 27: 502–522
  • Wems S. W., Fantone J. C., Ventura A., Lucchesi B. R. Myocardial glutathione depletion impairs recovery of isolated blood-perfused hearts after global ischemia. Journal of Molecular and Cellular Cardiology 1992; 24: 1215–1220
  • Anderson M. E., Powrie F., Puri R. N., Meister A. Glutathione monoethyl ester: preparation, uptake by tissues, and conversion to glutathione. Archives of Biochemistry and Biophysics 1985; 239: 538–548
  • Aw T. Y., Wierbicka G., Jones D. P. Oral glutathione increases tissue glutathione in vitro. Chemico-Biological Interactions 1991; 80: 89–97
  • Puri R. N., Meister A. Transport of g-glutamylcysteinylglycylester, into liver and kidney. Proceedings of National Academy of Science, USA, 80: 5258–5260
  • Richman P. G., Meister A. Regulation of g-glutamyl-cysteine synthetase by nonallosteric feedback inhibition by glutathione. Journal of Biological Chemistry 1975; 250: 1422–1426
  • Kaneko M., Hayashi H., Kobayashi A., Yamazaki N., Dalla N. S. Stunned myocardium and oxygen free radicals-sarcolemmal membrane damage due to oxygen free radicals. Japanese Circulation Journal 1991; 55: 885–892
  • Matsuola T., Kato M., Kako K. J. Effect of oxidants on Na, K, ATPase and its reversal. Basic. Research in Cardiology 1990; 85: 330–341
  • Meij J. T., Susoki S., Panagia V., Dalla N. S. Oxidative stress modifies the activity of cardiac sarco-lemmal phospholipase C. Biochimica et Biophysica Acta 1994; 1199: 6–12

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