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Original Article

The One-Electron Reduction Potential of 3-Amino-1, 2, 4-benzotriazine 1, 4-dioxide (Tirapazamine): A Hypoxia-Selective Bioreductive Drug

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Pages 393-399 | Received 19 Mar 1996, Published online: 07 Jul 2009

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  • Laderoute K., Wardman P., Rauth A. M. Molecular mechanisms for the hypoxia-dependent activation of 3-amino-l, 2, 4-benzotriazine-1, 4-dioxide (SR4233). Biochemical Pharmacology 1988; 37: 1487–95
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