12
Views
4
CrossRef citations to date
0
Altmetric
Original Article

Methylprednisolone Attenuates Airway and Vascular Responses Induced by Reactive Oxygen Species in Isolated, Plasma-Perfused Rat Lungs

, , , &
Pages 407-414 | Received 26 Jan 1996, Published online: 07 Jul 2009

References

  • Demling R. Role of oxygen radicals in acute lung injury. Adult Respiratory Distress Syndrome., A. Artigas, F. Lemaire, P. M. Suter, W. M. Zapol. Churchill Livingstone, Edinburgh-London-New York 1992; 121–140
  • Ryrfeldt A., Bannenberg G., Moldéus P. Free radicals and lung disease. British Medical Bulletin 1993; 49: 589–603
  • Adult Respiratory Distress Syndrome, A. Artigas, F. Lemaire, P. M. Suter, W. M. Zapol. Churchill Livingstone, Edinburgh-London-New York 1992
  • Sibbald W. J., Anderson R. R., Reid B., Holliday R. L. Alveolocapillary permeability in human septic ARDS. Effect of high-dose corticosteroid therapy. Chest 1981; 79: 133–142
  • Bernard G. R., Luce J. M., Sprung C. L., Rinaldo J. E., Tate R. M., Sibbald W. J., Kariman K., Higgins S., Bradley R., Metz C. A., Harris T. R., Brigham K. L. High-dose corticosteroids in patients with the adult respiratory distress syndrome. New England Journal of Medicine 1987; 317: 1565–1570
  • Svennevig J. L., Bugge-Asperheim B., Vaage J., Geiran O., Birkeland S. Corticosteroids in the treatment of blunt injury of the chest. Injury 1984; 16: 80–84
  • Tate R. M., Van Benthuysen K. M., Shasby D. M., McMurtry I. F., Repine J. E. Oxygen radical-mediated permeability edema and vasoconstriction in isolated perfused rabbit lungs. American Review of Respiratory Disease 1982; 126: 802–806
  • Burghuber O. C., Strife R. J., Zirrolli J., Henson P. M., Henson J. E., Mathias M. M., Reeves J. T., Myrphy R. C., Voelkel N. F. Leukotriene inhibitors attenuate rat lung injury induced by hydrogen peroxide. American Review of Respiratory Disease 1985; 131: 778–785
  • Kjæve J., Vaage J., Bjertnæs L. Reactive oxygen intermediates reduce inactivation of serotonin in isolated, perfused rat lungs. Circulatory Shock 1989; 28: 79–87
  • Kjæve J., Vaage J., Bjertnæs L. Increased microvascular permeability caused by toxic oxygen metabolites is partly reversed by exhanging the perfusate in isolated rat lungs. Acta Anaesthesiologica Scandinavica 1989; 33: 605–609
  • Kjæve J., Vaage J., Bjertnæs L. Toxic oxygen metabolites reduce inactivation of PG2 in isolated, perfused rat lungs. International Journal of Microcirculation.: Clinical and Experimental 1992; 11: 85–93
  • Kjæve J., Vaage J., Bjertnæs L. Toxic oxygen metabolites induce vasoconstriction and bronchoconstriction in isolated, plasma-perfused rat lungs. Acta Anaesthesiologica Scandinavica 1991; 35: 65–70
  • Olafsdottir K., Åyrfeldt R., Atzori L., Berggren M., Moldeus P. Hydroperoxide-induced broncho- and vasoconstriction in the isolated rat lung. Experimental Lung Research 1991; 17: 615–627
  • Olafsdottir K., Atzori L., Åyrfeldt R., Berggren M., Kumlin M., Moldeus P. Mechanisms of hydroperoxide-induced broncho- and vasoconstriction in isolated and perfused rat lung. Pharmacology and Toxicology 1991; 68: 191–186
  • Blackwell G. J., Flower R. J., Nijkamp F. P., Vane J. R. Phospholipase A2 activity of guinea-pig isolated perfused lungs: stimulation and inhibition by antiinflammatory steroids. British Journal of Pharmacology 1978; 62: 79–89
  • Hall E. D. The neuroprotective pharmacology of methylprednisolone. Journal of Neurosurgery 1992; 76: 13–22
  • Anderson D. K., Dugan L. L., Means E. D., Horrocks L. A. Methylprednisolone and membrane properties of primary cultures of mouse spinal cord. Brain Research 1994; 637: 119–125
  • Kjæve J., Naess L., Ingebrigtsen T., Vaage J., Bjertnæs L. Toxic oxygen metabolites increase microvascular permeability in isolated perfused rat lungs: The effect of methylprednisolone. Circulatory Shock 1991; 33: 228–232
  • Ytrehus K., Myklebust R., Mjøs O. D. Influence of oxygen radicals generated by xanthine oxidase in the isolated perfused rat heart. Cardiovascular Research 1986; 20: 597–603
  • Valen G., Semb A. G., Vaage J. Inhibition of lipooxygenase and cyclooxygenase augments cardiac injury by H2O2. Free Radical Biology & Medicine 1993; 15: 27–35
  • Kjæve J. Lungs and toxic oxygen metabolites. An experimental study. Thesis, University of Tromsø, TromsøNorway 1991; 24
  • Hauge A., Bö G., Aarseth P. Hydrostatic pulmonary edema in the cat. Effects on pulmonary blood and water volumes and on lung compliance. Acta Anaesthesiologica Scandinavica 1977; 21: 413–422
  • Goldstein I. M., Roos D., Weissman G., Kaplan H. B. Influence of corticosteroids on human polymorphonuclear leukocyte function in vitro. Inflammation 1976; 1: 305–315
  • Stromme-Hansen L., Bjertnæs L., Vaage J. Methylprednisolone reduces vascular resistance in hypoxic and atelectatic lungs. Acta Anaesthesiologica Scandinavica 1985; 29: 446–452
  • Braude A. C., Rebuck A. S. Prednisone and methylprednisolone disposition in the lung. Lancet 1983; 2: 995–997
  • Wilson J. W. Cellular localization of 3H-labelled corticosteroid by electron microscopic autoradiography after hemorragic shock. Steroids and Shock, T. M. Glenn. University park Press, Baltimore 1974; 275–289
  • Lefer A. M. Corticosteroid and circulatory function. Handbook of Physiology, Endocrinology VI. The American Physiological Society. 1976; 191–207
  • Vaage J. Effects of high-dose corticosteroids on the pulmonary circulation. Acta Chirurgica Scandinavica 1985; 73–82, Suppl. 526
  • Hall E. D., Braughler J. M. Glucocorticoid mechanisms in acute spinal cord injury: a review and therapeutic rationale. Journal of Neurosurgery 1982; 18: 320–327
  • Kawamura T., Yoshioka T., Bills T., Fogo A., Ichikawa I. Glucocorticoid activates glomerular antioxidant enzymes and protects glomeruli from antioxidant injuries. Kidney International 1991; 40: 291–301
  • Macconi D., Zanoli A. F., Orisio S., Longaretti L., Magrini L., Rota S., Radice A., Pozzi C., Remuzzi G. Methylprednisolone normalizes superoxide anion production by polymorphs from patients with ANCA-positive vasculitidis. Kidney International 1993; 44: 215–220
  • Yoshioka T., Kawamura T., Meyrick B. O., Beckman J. K., Hoover R. L., Yoshida H., Ichikawa I. Induction of manganese superoxide dismutase by glucocorticoids in glomerular cells. Kidney International 1994; 45: 211–219
  • Newman J. H., Fulkerson W. J., Kobayashi T., English D., Meyrick B., Brigham K. Effects of methylprednisolone on lung oxygen toxicity in awake sheep. Journal of Applied Physiology 1986; 60: 1386–1392
  • Critchley J. A., Beeley J. M., Clark R. J., Summerfield M., Bell S., Spurlock M. S., Edginton J. A., Buchanan J. D. Evaluation of N-acetylcysteine and methylprednisolone as therapies for oxygen and acrolein-induced lung damage. Environmental Health Perspectives 1990; 85: 89–94

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.