1,245
Views
11
CrossRef citations to date
0
Altmetric
Research Article

Ethinylestradiol liposome preparation and its effects on ovariectomized rats’ osteoporosis

, , , , &
Pages 468-477 | Received 31 Jan 2011, Accepted 15 May 2011, Published online: 20 Jun 2011

References

  • Ali MH, Kirby DJ, Mohammed AR, Perrie Y. 2010. Solubilisation of drugs within liposomal bilayers: alternatives to cholesterol as a membrane stabilizing agent. J Pharm Pharmacol 62:1–10.
  • Barenholz Y. 2001. Liposome application: problems and prospects. Current Opinion in Colloid & Interface Science 6:66–77.
  • Black DM, Eastell R, Boonen S, Bucci-Rechtweg C, Mesenbrink P. 2009. Time to onset of anti-fracture efficacy and persistence of effect of zoledronic acid 5 mg in women with osteoporosis or recent hip fracture. Bone 44: S234–S252
  • Boivin G, Vedi S, Purdie DW, Compston JE, Meunier PJ. 2005. Influence of estrogen therapy at conventional and high doses on the degree of mineralization of iliac bone tissue: a quantitative microradiographic analysis in postmenopausal women. Bone 36: 562–567.
  • Bonewald LF, Johnson ML. 2008. Osteocytes, mechanosensing and Wnt signaling. Bone 42: 606–615.
  • Breitman PL, Fonseca D, Cheung AM, Ward WE. 2003. Isoflavones with supplemental calcium provide greater protection against the loss of bone mass and strength after ovariectomy compared to isoflavones alone. Bone 33: 597–605.
  • Cederroth CR, Nef S. 2009. Soy, Phytoestrogens and metabolism: A review. Mol Cell Endocrinol 304: 30–42.
  • Cuzick J. 2008. Hormone replacement therapy,and the risk of breast cancer. European J Cancer 44: 2344–2349.
  • De Laet C, Kanis JA, Oden A, Johanson H, Johnell O, Delmas P. 2005. Body mass index as a predictor of fracture risk: a meta-analysis. Osteoporos Int 16: 1330–1338.
  • Demir B, Haberal A, Geyik P, Baskan B, Ozturkoglu E, Karacay O, Deveci S. 2008. Identification of the risk factors for osteoporosis among postmenopausal women. Maturitas 60:253–256.
  • Eskridge SL, Morton DJ. 2010. Estrogen Therapy and Bone Mineral Density in African-American and Caucasian Women. Am J Epidemiol 171: 808–816.
  • Feng YJ, Wang C, Liu JF, Zhang ZH. 2010. Electrochemical degradation of 17-alpha-ethinylestradiol (EE2) and estrogenic activity changes. J Environ Monit 12: 404–408.
  • Fonseca D, Ward WE. 2004. Daidzein together with high calcium preserve bone mass and biomechanical strength at multiple sites in ovariectomized mice. Bone 35: 489–497.
  • Garg M, Mishra D, Agashe H, Jain NK. 2006. Ethinylestradiol-loaded ultraflexible liposomes: pharmacokinetics and pharmacodynamics. J Pharm Pharmacol 58, 459–468.
  • Gobbi S, Cavalli A, Negri M, Schewe KE, Belluti F, Piazzi L, Hartmann RW, Recanatini M, Bisi A. 2007. Imidazolylmethylbenzophenones as highly potent aromatase inhibitors. J Med Chem 50:3420–3422.
  • Gregoriadis G, Davis C. 1979. Stability of liposomes in vivo and in vitro is promoted by their cholesterol content in the presence of blood cells. Biochim Biophys Res Commun 90: 1287–1293.
  • Hagino H, Nishizawa Y, Sone T, Morii H, Taketani Y, Nakamura T, Itabashi A, Mizunuma H, Ohashi Y, Shiraki M, Minamide T, Matsumoto T. 2009. A double-blinded head-to-head trial of minodronate and alendronate in women with postmenopausal osteoporosis. Bone 44: 1078–1084.
  • Hathout RM, Mansour S, Mortada ND, Guinedi AS. 2007. Liposomes as an ocular delivery system for acetazolamide: in vitro and in vivo studies. AAPS PharmSciTech 8(1):E1–E12.
  • Hengst V, Oussoren C, Kissel T, Storm G. 2007. Bone targeting potential of bisphosphonate-targeted liposomes Preparation, characterization and hydroxyapatite binding in vitro. Int J Pharm 331: 224–227.
  • Hughes GA. 2005. Nanostructure-mediated drug delivery. Nanomedicine: Nanotechnol Biol Med 1: 22–30.
  • Kateb NE, Cynober L, Chaumeil JC, Dumortier G. 2008. L-cysteine encapsulation in liposomes: Effect of phospholipids nature on entrapment efficiency and stability. J Microencapsulation 25(6): 399–413.
  • Kirby C, Gregoriadis G. 1980. Effect of the cholesterol content of small unilamellar liposomes on their stability in vivo and in vitro. Biochem J 186: 591–598.
  • Kita M, Kondo M, Koyama T, Yamada K, Matsumoto T, Lee K, Woo J, Uemura D. 2004. Symbioimine exhibiting inhibitory effect of osteoclast differentiation, from the symbiotic marine dinoflagellate symbiodinium sp. J Am Chem Soc 126: 4794–4795.
  • Lindenfeld EA, Langer RD. 2002. Bleeding patterns of the hormone replacement therapies in the postmenopausal estrogen and progestin interventions trial. Obstet Gynecol 100: 853–863.
  • Makras P, Hamdy NAT, Zwinderman AH, Ballieux BEPB, Papapoulos SE. 2009. Bisphosphonate dose and incidence of fractures in postmenopausal osteoporosis. Bone 44: 766–771.
  • Mamot C, Drummond DC, Hong K, Kirpotin D, Park JW. 2003. Liposome-based approaches to overcome anticancer drug resistance. Drug Resist Updat 6:271–279.
  • Mohammed AR, Weston N, Coombes AGA, Fitzgerald M, Perrie Y. 2004. Liposome formulation of poorly water soluble drugs: optimisation of drug loading and ESEM analysis of stability. Int J Pharmaceutics 285: 23–34.
  • Nounou MM, EL-Khordagui LK, Khalafalla NA, Khalil SA. 2006. In vitro release of hydrophilic and hydrophobic drugs from liposomal dispersions and gels. Acta Pharm 56: 311–324.
  • Otsuka M, Oshinbe A, LeGeros RZ, Tokudome Y, Ito A, Otsuka K, Higuchi WI. 2008. Efficacy of the injectable calcium phosphate ceramics suspensions containing magnesium, zinc and fluoride on the bone mineral deficiency in ovariectomized rats. J Pharm Sci 97: 421–432.
  • Pasco JA, Henry MJ, Nicholson GC, Brennan SL, Kotowicz MA. 2009. Behavioural and physical characteristics associated with vitamin D status in women. Bone 44: 1085–1091.
  • Peng KW, Wang HL, Qin ZH, Wijewickrama GT, Lu ML, Wang ZC, Bolton JL, Thatcher GRJ. 2009. Selective Estrogen Receptor Modulator Delivery of Quinone Warheads to DNA Triggering Apoptosis in Breast Cancer Cells. ACS Chem. Biol. 4: 1039–1049
  • Peng KW, Chang MS, Wang YT, Wang ZC, Qin ZH, Bolton JL, Thatcher GRJ. 2010. Unexpected Hormonal Activity of a Catechol Equine Estrogen Metabolite Reveals Reversible Glutathione Conjugation. Chem. Res. Toxicol. 23: 1374–1383
  • Poiana C, Carsote M, Neacsu E, Barbu C, Gruia A, Samoila R, Ene C. 2009. Vitamin D levels and bone mineral density in 174 postmenopausal. Bone 44: S398.
  • Quadir MA, Radowski MR, Kratz F, Licha K, Hauff P, Haag R. 2008. Dendritic multishell architectures for drug and dye transport. J Control Release 132: 289–294.
  • Raudaskoski T, Tapanainen J, Tomás E, Luotola H, Pekonen F, Ronni-Sivula H, Timonen H, Riphagen F, Laatikainen T. 2002. Intrauterine 10μg and 20μg levonorgestrel systems in postmenopausal women receiving oral oestrogen replacement therapy: clinical, endometrial and metabolic response. BJOG: An Int J Obstet Gynaecol 109: 136–144.
  • Renoir J, Stella B, Ameller T, Connault E, Opolon P, Marsaud V. 2006. Improved anti-tumoral capacity of mixed and pure anti-oestrogens in breast cancer cell xenografts after their administration by entrapment in colloidal nanosystems. J Steroid Biochem Mol Biol 102: 114–127.
  • Riera-Espinoza GS, Ramos J, Belzares E. 2009. Vitamin D deficiency in postmenopausal women with osteoporosis in Venezuela. Bone 44: S359.
  • Rizzoli R, Felsenberg D, Laroche M, Seeman E, Krieg M, Frieling I, Thomas T, Delmas P. 2009. Strontium ranelate has a more positive influence than alendronate on distal tibia cortical and trabecular bone microstructure in women with postmenopausal osteoporosis. Bone 44: S211–S226.
  • Schindeler A, Little DG. 2007. Bisphosphonate action: Revelations and deceptions from in vitro studies. J Pharm Sci 96: 1872–1878.
  • Schmidt JM, Tremblay GB, Plastina MA, Ma F, Bhal S, Feher M, Dunn-Dufault R., Redden PR. 2005. In vitro evaluation of the anti-estrogenic activity of hydroxyl substituted diphenylnaphthyl alkene ligands for the estrogen receptor. Bioorg Med Chem 13: 1819–1828.
  • Setchell KDR, Brzezinski A, Brown NM, Desai PB, Melhem M, Meredith T, Zimmer-Nechimias L, Wolfe B, Cohen Y, Blatt Y. 2005. Pharmacokinetics of a slow-release formulation of soybean isoflavones in healthy postmenopausal women. J Agric Food Chem 53:1938–1944.
  • Shargorodsky M, Boaz M, Luckish A, Matas Z, Gavish D, Mashavi M. 2009. Osteoprotegerin as an independent marker of subclinical atherosclerosis in osteoporotic postmenopausal women. Atherosclerosis 204: 608–611.
  • Suzuki Y, Nagase Y, Iga K, Kawase M, Oka M, Yanai S, Matsumoto Y, Nakagawa S, Fukuda T, Adachi H, Higo N, Ogawa Y. 2002. Prevention of bone loss in ovariectomized rats by pulsatile transdermal iontophoretic administration of human PTH(1-34). J Pharm Sci 91: 350–361.
  • Tabasum Parvez MD, 2004. Postmenopausal osteoporosis. JK-Practitioner 11(4): 281–283
  • Timmer MHM, Samson MM, Monninkhof EM, Ree BD, Verhaar HJJ. 2009. Predicting osteoporosis in patients with a low-energy fracture. Arch Gerontol Geriatr 49: e32–e35
  • Tyler CR, Filby AL, Bickley LK, Cumming RI, Gibson R, Labadie P, Katsu Y, Liney KE, Shears JA, Silva-Castro V, Urushitani H, Lange A, Winter MJ, Iguchi T, Hill EM. 2009. Environmental health impacts of equine estrogens derived from hormone replacement therapy. Environ Sci Technol 43: 3897–3904.
  • Uusi-Rasi K, Rauhio A, Kannus P, Pasanen M, Kukkonen-Harjula K, Fogelholm M, Sievänen H. 2010. Three-month weight reduction does not compromise bone strength in obese premenopausal women. Bone 46:1286–1293.
  • Vangala A, Kirby D, Rosenkrands I, Agger EM, Andersen P, Perrie Y. 2006. A comparative study of cationic liposome and niosome-based adjuvent systems for protein subunit vaccines: characterisation, environmental scanning electron microscopy and immunisation studies in mice. J Pharm Pharmacol 58:787–799.
  • Widler L, Jaeggi KA, Glatt M, Müller K, Bachmann R, Bisping M, Born A, Cortesi R, Guiglia G, Jeker H, Klein R, Ramseier U, Schmid J, Schreiber G, Seltenmeyer Y, Green JR. 2002. Highly potent geminal bisphosphonates. From pamidronate disodium (aredia) to zoledronic acid (zometa). J Med Chem 45: 3721–3738.
  • Zhou Y, Zhu Z, Guan XU, Hou W, Yu H. 2009. Reciprocal roles between caffeine and estrogen on bone via differently regulating cAMP/PKA pathway: The possible mechanism for caffeine-induced osteoporosis in women and estrogen’s antagonistic effects. Med Hypotheses 73: 83–85.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.