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Original Paper

Preparation of camptothecin-loaded targeting nanoparticles and their antitumor effects on hepatocellular carcinoma cell line H22

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Pages 1699-1706 | Received 05 Jun 2014, Accepted 29 Jul 2014, Published online: 22 Aug 2014

References

  • Bahadur RKC, Chandrashekaran V, Cheng B, et al. (2014). Redox potential ultrasensitive nanoparticle for the targeted delivery of camptothecin to HER2-positive cancer cells. Mol Pharmaceut 11:1897–905
  • Bildstein L, Dubernet C, Couvreur P. (2011). Prodrug-based intracellular delivery of anticancer agents. Adv Drug Deliv Rev 63:3–23
  • Byrne JD, Betancourt T, Brannon-Peppas L. (2008). Active targeting schemes for nanoparticle systems in cancer therapeutics. Adv Drug Deliv Rev 60:1615–26
  • Chen H, Gao J, Lu Y, et al. (2008). Preparation and characterization of PE38KDEL-loaded anti-HER2 nanoparticles for targeted cancer therapy. J Control Release 128:209–16
  • Cırpanlı Y, Allard E, Passirani C, et al. (2011). Antitumoral activity of camptothecin-loaded nanoparticles in 9L rat glioma model. Int J Pharm 403:201–6
  • Çirpanli Y, Bilensoy E, Dogan AL, Çalis S. (2009). Comparative evaluation of polymeric and amphiphilic cyclodextrin nanoparticles for effective camptothecin delivery. Eur J Pharm Biopharm 73:82–9
  • Cirstoiu-Hapca A, Buchegger F, Lange N, et al. (2010). Benefit of anti-HER2-coated paclitaxel-loaded immuno-nanoparticles in the treatment of disseminated ovarian cancer: therapeutic efficacy and biodistribution in mice. J Control Release 144:324–31
  • Fan HL, Huang J, Li YP, et al. (2010). Fabrication of reduction degradable micelle based on disulfide-linked graft copolymer-camptothecin conjugate for enhancing solubility and stability of camptothecin. Polymer 515:107–14
  • Fay F, McLaughlin KM, Small DM, et al. (2011). Conatumumab (AMG 655) coated nanoparticles for targeted pro-apoptotic drug delivery. Biomaterials 32: 8645–53
  • Ferlay J, Shin HR, Bray F, et al. (2010). Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 127:2893–917
  • Garcia-Carbonero R, Supko JG. (2002). Current perspectives on the clinical experience, pharmacology, and continued development of the camptothecins. Clin Cancer Res 8:641–61
  • Guo Q, Luo P, Luo Y, et al. (2012). Fabrication of biodegradable micelles with sheddable poly(ethylene glycol) shells as the carrier of 7-ethyl-10-hydroxy-camptothecin. Colloid Surface B 100:138–45
  • Heldin CH, Rubin K, Pietras K, Ostman A. (2004). High interstitial fluid pressure – an obstacle in cancer therapy. Nat Rev Cancer 4:806–13
  • Hong M, Zhu S, Jiang Y, et al. (2010). Novel anti-tumor strategy: PEG-hydroxycamptothecin conjugate loaded transferring-PEG-nanoparticles. J Control Release 141:22–9
  • Jia LJ, Zhang DR, Li ZY, et al. (2010). Nanostructured lipid carriers for parenteral delivery of silybin: biodistribution and pharmacokinetic studies. Colloids Surf B 80:213–18
  • Kocbek P, Obermajer N, Cegnar M, et al. (2007). Targeting cancer cells using PLGA nanoparticles surface modified with monoclonal antibody. J Control Release 120:18–26
  • Kunii R, Onishi H, Machida Y. (2007). Preparation and antitumor characteristics of PLA/(PEG-PPG-PEG) nanoparticles loaded with camptothecin. Eur J Pharm Sci 67:9–17
  • Lei TJ, Srinivasan S, Tang Y, et al. (2011). Comparing cellular uptake and cytotoxicity of targeted drug carriers in cancer cell lines with different drug resistance mechanisms. Nanomed Nanotechnol 7:324–32
  • Li ZL, Xiong XY, Li YP, et al. (2010). Synthesis and self-assembling behaviors of biotinylated pluronic/poly(lactic acid) biocompatible block copolymers in aqueous solutions. J Appl Polym Sci 115:1573–80
  • Liang FY, Zhang SH, Pan Y, et al. (1999). Use of monoclonal antibody norcantharidin conjugate in experimental targeting therapy of tumor. Chin J Zoology 34:18–22
  • Luo ZL, Jiang JW. (2012). pH-sensitive drug loading/releasing in amphiphilic copolymer PAE-PEG: Integrating molecular dynamics and dissipative particle dynamics simulations. J Control Release 162:185–93
  • McCarron PA, Marouf WM, Quinn DJ, et al. (2008). Antibody targeting of camptothecin-loaded PLGA nanoparticles to tumor cells. Bioconjugate Chem 19:1561–9
  • Modi S, Xiang TX, Anderson BD. (2012). Enhanced active liposomal loading of a poorly soluble ionizable drug using supersaturated drug solutions. J Control Release 162:330–9
  • Okamura K, Koike H, Sekine Y, et al. (2009). Survivin and its spliced isoform gene expression is associated with proliferation of renal cancer cells and clinical stage of renal cancer. Cancer Epidemiol 33:137–41
  • Paranjpe PV, Chen Y, Kholodovych V, et al. (2004). Tumor-targeted bioconjugate based delivery of camptothecin: design, synthesis and in vitro evaluation. J Control Release 100:275–92
  • Pardridge WM. (2007). Drug targeting to the brain. Pharm Res 24:1733–44
  • Pulkkinen M, Pikkarainen J, Wirth T, et al. (2008). Three-step tumor targeting of paclitaxel using biotinylated PLA-PEG nanoparticles and avidin-biotin technology: formulation development and in vitro anticancer activity. Eur J Pharm Biopharm 70:66–74
  • Shenderova A, Burke TG, Schwendeman SP. (1999). The acidic microclimate in poly(lactide-co-glycolide) microspheres stabilizes camptothecins. Pharm Res 16:241–8
  • Shukla R, Thomas TP, Peters JL, et al. (2006). HER2 specific tumor targeting with dendrimer conjugated anti-HER2 mAb. Bioconjugate Chem 17:1109–15
  • Stauber RH, Mann W, Knauer SK. (2007). Nuclear and cytoplasmic Survivin: molecular mechanism, prognostic, and the therapeutic potential. Cancer Res 67:5999–6002
  • Sun B, Ranganathan B, Feng SS. (2008). Multifunctional poly(D, L-lactide-co-glycolide)/montmorillonite (PLGA/MMT) nanoparticles decorated by Trastuzumab for targeted chemotherapy of breast cancer. Biomaterials 29:475–86
  • Swaminathan S, Pastero L, Serpe L, et al. (2010). Cyclodextrin-based nanosponges encapsulating camptothecin: physicochemical characterization, stability and cytotoxicity. Eur J Pharm Biopharm 74:193–201
  • Topcu Z. (2001). DNA topoisomerases as targets for anticancer drugs. J Clin Pharm Therap 26:405–16
  • Venditto VJ, Simanek EE. (2010). Cancer therapies utilizing the camptothecins: a review of the in vivo literature. Mol Pharm 7:307–49
  • Xiong XY, Guo L, Gong YC, et al. (2012). In vitro & in vivo targeting behaviors of biotinylated Pluronic F127/poly(lactic acid) nanoparticles through biotin-avidin interaction. Eur J Pharm Sci 46:537–44
  • Yang AS, Yang L, Liu W, et al. (2007). Tumor necrosis factor alpha blocking peptide loaded PEG-PLGA nanoparticles: preparation and in vitro evaluation. Int J Pharm 331:123–32

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